Non-autonomous crosstalk between the Jak/Stat and Egfr pathways mediates Apc1-driven intestinal stem cell hyperplasia in the Drosophila adult midgut

Development (Cambridge)

Volumn 139, Issue 24, 2012, Pages 4524-4535

  Cordero, Julia B ^a   Stefanatos, Rhoda K ^b   Myant, Kevin ^a   Vidal, Marcos ^b   Sansom, Owen J ^a  

^a Wnt Signaling and Colorectal Cancer Group   (United Kingdom)

^b BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

Author keywords

Apc; Drosophila midgut; Egfr; Intestinal stem cells; Myc; Stat

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; MYC PROTEIN; STAT PROTEIN; WNT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CLONE; COLON POLYPOSIS; COLORECTAL CANCER; DROSOPHILA; ENZYME ACTIVATION; HISTOLOGY; HYPERPLASIA; INTESTINAL STEM CELL; INTESTINE; LIFESPAN; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STEM CELL;

ADULT STEM CELLS; AGE FACTORS; ANIMALS; ANIMALS, GENETICALLY MODIFIED; DNA REPLICATION; DROSOPHILA; DROSOPHILA PROTEINS; ENTEROCYTES; HYPERPLASIA; INTESTINES; JANUS KINASES; RECEPTOR CROSS-TALK; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTORS, INVERTEBRATE PEPTIDE; SIGNAL TRANSDUCTION; STAT TRANSCRIPTION FACTORS; TRANSCRIPTION FACTORS;

EID: 84870044742     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.078261     Document Type: Article

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