Mammary epithelial-specific disruption of c-Src impairs cell cycle progression and tumorigenesis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 8, 2012, Pages 2808-2813

  Marcotte, Richard ^a,c   Smith, Harvey W ^a   Sanguin Gendreau, Virginie ^a   McDonough, Rosalie V ^b   Muller, William J ^a  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

Conditional gene targeting; Mammary tumor progression; Transgenic models of breast cancer; Tumor cell proliferation; Tyrosine kinase signaling

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR; CYCLINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST EPITHELIUM; CARCINOGENESIS; CELL ADHESION; CELL CYCLE PROGRESSION; CELL PROLIFERATION; GENE SILENCING; MOUSE; NONHUMAN; ONCOGENE SRC; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR CELL; TUMOR GROWTH;

ANIMALS; ANTIGENS, POLYOMAVIRUS TRANSFORMING; CELL ADHESION; CELL CYCLE; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; CYCLIN-DEPENDENT KINASE INHIBITOR PROTEINS; CYCLINS; DISEASE PROGRESSION; EPITHELIUM; FEMALE; GENE DELETION; GENE SILENCING; HUMANS; MAMMARY GLANDS, ANIMAL; MAMMARY TUMOR VIRUS, MOUSE; MICE; MICE, NUDE; ORGAN SPECIFICITY; PHOSPHORYLATION; SRC-FAMILY KINASES;

EID: 84857402960     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1018861108     Document Type: Article

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