The roles of blood-derived macrophages and resident microglia in the neuroinflammatory response to implanted Intracortical microelectrodes

Biomaterials

Volumn 35, Issue 28, 2014, Pages 8049-8064

  Ravikumar, Madhumitha ^a,c   Sunil, Smrithi ^a,c   Black, James ^a   Barkauskas, Deborah S ^a,b   Haung, Alex Y ^b   Miller, Robert H ^b   Selkirk, Stephen M ^b,c   Capadona, Jeffrey R ^a,c  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c LOUIS STOKES CLEVELAND VA MEDICAL CENTER   (United States)

Author keywords

Macrophage; Microelectrode; Microglia; Neuroinflammation

Indexed keywords

BLOOD; CELL CULTURE; CELL PROLIFERATION; MACROPHAGES; NEURAL PROSTHESES; NEURONS;

CELL POPULATIONS; CELLULAR MARKERS; MICROGLIA; NEURODEGENERATION; NEUROINFLAMMATION; NEURON POPULATION; NEURONAL SURVIVAL; POST-IMPLANTATION;

MICROELECTRODES;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD; BONE MARROW; BRAIN TISSUE; CELL DENSITY; CELL POPULATION; CELL SURVIVAL; CELL TYPE; CONTROLLED STUDY; CORTICAL ELECTRODE; ELECTRODE IMPLANT; IMPLANTATION; MACROPHAGE; MICROELECTRODE; MICROGLIA; MOUSE; NERVE CELL; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; TISSUE SECTION; ANIMAL; ASTROCYTE; BLOOD BRAIN BARRIER; C57BL MOUSE; CELL MOTION; CHEMISTRY; CYTOLOGY; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MALE; METABOLISM; PATHOLOGY; PROSTHESES AND ORTHOSES;

CYAN FLUORESCENT PROTEIN; GREEN FLUORESCENT PROTEIN; IMMUNOGLOBULIN G;

ANIMALS; ASTROCYTES; BLOOD-BRAIN BARRIER; CELL MOVEMENT; ELECTRODES, IMPLANTED; GREEN FLUORESCENT PROTEINS; IMMUNOGLOBULIN G; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICROELECTRODES; MICROGLIA; NEURONS; PROSTHESES AND IMPLANTS;

EID: 84903696391     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2014.05.084     Document Type: Article

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