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Volumn 13, Issue 2, 2014, Pages 94-104

Reciprocity in microbiome and immune system interactions and its implications in disease and health

Author keywords

Adaptive and innate immunity; Autoimmunity; Helper T cells; Immune regulation; Immune system; Microbial diversity; Microbiome; Probiotics

Indexed keywords

ANTIBIOTIC AGENT; ANTIGEN; AROMATIC HYDROCARBON RECEPTOR; CD103 ANTIGEN; CD4 ANTIGEN; CHEMOKINE RECEPTOR CCR6; CHEMOKINE RECEPTOR CX3CR1; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 43; GAMMA INTERFERON; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 22; INTERLEUKIN 23; INTERLEUKIN 4; LYMPHOTOXIN BETA RECEPTOR; MYELOID DIFFERENTIATION FACTOR 88; POLYSACCHARIDE ANTIGEN; PROBIOTIC AGENT; SECRETORY IMMUNOGLOBULIN; SHORT CHAIN FATTY ACID; TESTOSTERONE; TOLL LIKE RECEPTOR 2; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTION FACTOR T BET; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; IMMUNOGLOBULIN RECEPTOR; IMMUNOLOGIC FACTOR; ADENOSINE TRIPHOSPHATE; BIOLOGICAL MARKER; HISTONE DEACETYLASE; IMMUNE RECEPTOR; IMMUNOGLOBULIN A; INTERLEUKIN 12; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; MESSENGER RNA; NITRIC OXIDE; RECEPTOR; TRANSFORMING GROWTH FACTOR BETA;

EID: 84903691818     PISSN: 18715281     EISSN: None     Source Type: Journal    
DOI: 10.2174/1871528113666140330201056     Document Type: Article
Times cited : (27)

References (127)
  • 3
    • 84879564304 scopus 로고    scopus 로고
    • Specific gut commensal flora locally alters T cell tuning to endogenous ligands
    • Chappert, P.; Bouladoux, N.; Naik, S.; Schwartz, R. H. Specific gut commensal flora locally alters T cell tuning to endogenous ligands. Immunity, 2013, 38 (6), 1198-1210.
    • (2013) Immunity , vol.38 , Issue.6 , pp. 1198-1210
    • Chappert, P.1    Bouladoux, N.2    Naik, S.3    Schwartz, R.H.4
  • 4
    • 53349173070 scopus 로고    scopus 로고
    • Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine
    • Ivanov, I. I.; Frutos, R. L.; Manel, N.; Yoshinaga, K.; Rifkin, D. B.; Sartor, R. B.; Finlay, B. B.; Littman, D. R. Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine. Cell Host. Microbe, 2008, 4 (4), 337-349.
    • (2008) Cell Host. Microbe , vol.4 , Issue.4 , pp. 337-349
    • Ivanov, I.I.1    Frutos, R.L.2    Manel, N.3    Yoshinaga, K.4    Rifkin, D.B.5    Sartor, R.B.6    Finlay, B.B.7    Littman, D.R.8
  • 6
    • 0037112050 scopus 로고    scopus 로고
    • Critical roles of activation-induced cytidine deaminase in the homeostasis of gut flora
    • Fagarasan, S.; Muramatsu, M.; Suzuki, K.; Nagaoka, H.; Hiai, H.; Honjo, T. Critical roles of activation-induced cytidine deaminase in the homeostasis of gut flora. Science, 2002, 298 (5597), 1424-1427.
    • (2002) Science , vol.298 , Issue.5597 , pp. 1424-1427
    • Fagarasan, S.1    Muramatsu, M.2    Suzuki, K.3    Nagaoka, H.4    Hiai, H.5    Honjo, T.6
  • 7
    • 22144490199 scopus 로고    scopus 로고
    • An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system
    • Mazmanian, S. K.; Liu, C. H.; Tzianabos, A. O.; Kasper, D. L. An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system. Cell, 2005, 122 (1), 107-118.
    • (2005) Cell , vol.122 , Issue.1 , pp. 107-118
    • Mazmanian, S.K.1    Liu, C.H.2    Tzianabos, A.O.3    Kasper, D.L.4
  • 8
    • 44449106055 scopus 로고    scopus 로고
    • A microbial symbiosis factor prevents intestinal inflammatory disease
    • Mazmanian, S. K.; Round, J. L.; Kasper, D. L. A microbial symbiosis factor prevents intestinal inflammatory disease. Nature, 2008, 453 (7195), 620-625.
    • (2008) Nature , vol.453 , Issue.7195 , pp. 620-625
    • Mazmanian, S.K.1    Round, J.L.2    Kasper, D.L.3
  • 9
    • 77954738601 scopus 로고    scopus 로고
    • Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota
    • Round, J. L.; Mazmanian, S. K. Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota. Proc. Natl. Acad. Sci. U. S. A, 2010, 107 (27), 12204-12209.
    • (2010) Proc. Natl. Acad. Sci. U. S. A , vol.107 , Issue.27 , pp. 12204-12209
    • Round, J.L.1    Mazmanian, S.K.2
  • 10
    • 79956311926 scopus 로고    scopus 로고
    • The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota
    • Round, J. L.; Lee, S. M.; Li, J.; Tran, G.; Jabri, B.; Chatila, T. A.; Mazmanian, S. K. The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota. Science, 2011, 332 (6032), 974-977.
    • (2011) Science , vol.332 , Issue.6032 , pp. 974-977
    • Round, J.L.1    Lee, S.M.2    Li, J.3    Tran, G.4    Jabri, B.5    Chatila, T.A.6    Mazmanian, S.K.7
  • 13
    • 77958119730 scopus 로고    scopus 로고
    • Central nervous system demyelinating disease protection by the human commensal Bacteroides fragilis depends on polysaccharide A expression
    • Ochoa-Reparaz, J.; Mielcarz, D. W.; Ditrio, L. E.; Burroughs, A. R.; Begum-Haque, S.; Dasgupta, S.; Kasper, D. L.; Kasper, L. H. Central nervous system demyelinating disease protection by the human commensal Bacteroides fragilis depends on polysaccharide A expression. J. Immunol., 2010, 185 (7), 4101-4108.
    • (2010) J. Immunol , vol.185 , Issue.7 , pp. 4101-4108
    • Ochoa-Reparaz, J.1    Mielcarz, D.W.2    Ditrio, L.E.3    Burroughs, A.R.4    Begum-Haque, S.5    Dasgupta, S.6    Kasper, D.L.7    Kasper, L.H.8
  • 16
    • 84866461477 scopus 로고    scopus 로고
    • Familial transmission rather than defective innate immunity shapes the distinct intestinal microbiota of TLR-deficient mice
    • Ubeda, C.; Lipuma, L.; Gobourne, A.; Viale, A.; Leiner, I.; Equinda, M.; Khanin, R.; Pamer, E. G. Familial transmission rather than defective innate immunity shapes the distinct intestinal microbiota of TLR-deficient mice. J. Exp. Med., 2012, 209 (8), 1445-1456.
    • (2012) J. Exp. Med , vol.209 , Issue.8 , pp. 1445-1456
    • Ubeda, C.1    Lipuma, L.2    Gobourne, A.3    Viale, A.4    Leiner, I.5    Equinda, M.6    Khanin, R.7    Pamer, E.G.8
  • 17
    • 56749146467 scopus 로고    scopus 로고
    • Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis
    • Bouskra, D.; Brezillon, C.; Berard, M.; Werts, C.; Varona, R.; Boneca, I. G.; Eberl, G. Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis. Nature, 2008, 456 (7221), 507-510.
    • (2008) Nature , vol.456 , Issue.7221 , pp. 507-510
    • Bouskra, D.1    Brezillon, C.2    Berard, M.3    Werts, C.4    Varona, R.5    Boneca, I.G.6    Eberl, G.7
  • 20
    • 84891714236 scopus 로고    scopus 로고
    • Modulation of autoimmune diseases by interleukin (IL)-17 producing regulatory T helper (Th17) cells
    • Singh, B.; Schwartz, J. A.; Sandrock, C.; Bellemore, S. M.; Nikoopour, E. Modulation of autoimmune diseases by interleukin (IL)-17 producing regulatory T helper (Th17) cells. Indian J. Med. Res., 2013, 138 (5), 591-594.
    • (2013) Indian. J. Med. Res , vol.138 , Issue.5 , pp. 591-594
    • Singh, B.1    Schwartz, J.A.2    Sandrock, C.3    Bellemore, S.M.4    Nikoopour, E.5
  • 24
    • 79960983258 scopus 로고    scopus 로고
    • Naturally transmitted segmented filamentous bacteria segregate with diabetes protection in nonobese diabetic mice
    • Kriegel, M. A.; Sefik, E.; Hill, J. A.; Wu, H. J.; Benoist, C.; Mathis, D. Naturally transmitted segmented filamentous bacteria segregate with diabetes protection in nonobese diabetic mice. Proc. Natl. Acad. Sci. U. S. A, 2011, 108 (28), 11548-11553.
    • (2011) Proc. Natl. Acad. Sci. U. S. A , vol.108 , Issue.28 , pp. 11548-11553
    • Kriegel, M.A.1    Sefik, E.2    Hill, J.A.3    Wu, H.J.4    Benoist, C.5    Mathis, D.6
  • 25
    • 84860145932 scopus 로고    scopus 로고
    • Research highlights: Highlights from the latest articles in immunotherapy
    • Summers, K. L.; Singh, B. Research highlights: highlights from the latest articles in immunotherapy. Immunotherapy, 2012, 4 (4), 363-364.
    • (2012) Immunotherapy , vol.4 , Issue.4 , pp. 363-364
    • Summers, K.L.1    Singh, B.2
  • 27
    • 79952748674 scopus 로고    scopus 로고
    • Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitis
    • Lee, Y. K.; Menezes, J. S.; Umesaki, Y.; Mazmanian, S. K. Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitis. Proc. Natl. Acad. Sci. U. S. A, 2011, 108 (Suppl 1) 4615-4622.
    • (2011) Proc. Natl. Acad. Sci. U. S. A , vol.108 , Issue.SUPPL. 1 , pp. 4615-4622
    • Lee, Y.K.1    Menezes, J.S.2    Umesaki, Y.3    Mazmanian, S.K.4
  • 29
    • 0033004028 scopus 로고    scopus 로고
    • Segmented filamentous bacteria are potent stimuli of a physiologically normal state of the murine gut mucosal immune system
    • Talham, G. L.; Jiang, H. Q.; Bos, N. A.; Cebra, J. J. Segmented filamentous bacteria are potent stimuli of a physiologically normal state of the murine gut mucosal immune system. Infect. Immun., 1999, 67 (4), 1992-2000.
    • (1999) Infect. Immun , vol.67 , Issue.4 , pp. 1992-2000
    • Talham, G.L.1    Jiang, H.Q.2    Bos, N.A.3    Cebra, J.J.4
  • 31
    • 84870243802 scopus 로고    scopus 로고
    • Functional flexibility of intestinal IgA-broadening the fine line
    • Slack, E.; Balmer, M. L.; Fritz, J. H.; Hapfelmeier, S. Functional flexibility of intestinal IgA-broadening the fine line. Front Immunol., 2012, 3, 100.
    • (2012) Front Immunol , vol.3 , pp. 100
    • Slack, E.1    Balmer, M.L.2    Fritz, J.H.3    Hapfelmeier, S.4
  • 32
    • 1542618118 scopus 로고    scopus 로고
    • Induction of protective IgA by intestinal dendritic cells carrying commensal bacteria
    • Macpherson, A. J.; Uhr, T. Induction of protective IgA by intestinal dendritic cells carrying commensal bacteria. Science, 2004, 303 (5664), 1662-1665.
    • (2004) Science , vol.303 , Issue.5664 , pp. 1662-1665
    • Macpherson, A.J.1    Uhr, T.2
  • 34
    • 79951602552 scopus 로고    scopus 로고
    • Mice carrying a knock-in mutation of Aicda resulting in a defect in somatic hypermutation have impaired gut homeostasis and compromised mucosal defense
    • Wei, M.; Shinkura, R.; Doi, Y.; Maruya, M.; Fagarasan, S.; Honjo, T. Mice carrying a knock-in mutation of Aicda resulting in a defect in somatic hypermutation have impaired gut homeostasis and compromised mucosal defense. Nat. Immunol., 2011, 12 (3), 264-270.
    • (2011) Nat. Immunol , vol.12 , Issue.3 , pp. 264-270
    • Wei, M.1    Shinkura, R.2    Doi, Y.3    Maruya, M.4    Fagarasan, S.5    Honjo, T.6
  • 35
    • 77949911050 scopus 로고    scopus 로고
    • Enteric flora expands gut lamina propria CX3CR1+ dendritic cells supporting inflammatory immune responses under normal and inflammatory conditions
    • Niess, J. H.; Adler, G. Enteric flora expands gut lamina propria CX3CR1+ dendritic cells supporting inflammatory immune responses under normal and inflammatory conditions. J. Immunol., 2010, 184 (4), 2026-2037.
    • (2010) J. Immunol , vol.184 , Issue.4 , pp. 2026-2037
    • Niess, J.H.1    Adler, G.2
  • 36
    • 34547788180 scopus 로고    scopus 로고
    • A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism
    • Coombes, J. L.; Siddiqui, K. R.; rancibia-Carcamo, C. V.; Hall, J.; Sun, C. M.; Belkaid, Y.; Powrie, F. A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism. J. Exp. Med., 2007, 204 (8), 1757-1764.
    • (2007) J. Exp. Med , vol.204 , Issue.8 , pp. 1757-1764
    • Coombes, J.L.1    Siddiqui, K.R.2    Rancibia-Carcamo, C.V.3    Hall, J.4    Sun, C.M.5    Belkaid, Y.6    Powrie, F.7
  • 37
    • 44349132270 scopus 로고    scopus 로고
    • Epithelial-cell recognition of commensal bacteria and maintenance of immune homeostasis in the gut
    • Artis, D. Epithelial-cell recognition of commensal bacteria and maintenance of immune homeostasis in the gut. Nat. Rev. Immunol., 2008, 8 (6), 411-420.
    • (2008) Nat. Rev. Immunol , vol.8 , Issue.6 , pp. 411-420
    • Artis, D.1
  • 43
    • 3242664636 scopus 로고    scopus 로고
    • Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis
    • Rakoff-Nahoum, S.; Paglino, J.; Eslami-Varzaneh, F.; Edberg, S.; Medzhitov, R. Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis. Cell, 2004, 118 (2), 229-241.
    • (2004) Cell , vol.118 , Issue.2 , pp. 229-241
    • Rakoff-Nahoum, S.1    Paglino, J.2    Eslami-Varzaneh, F.3    Edberg, S.4    Medzhitov, R.5
  • 45
    • 51349099975 scopus 로고    scopus 로고
    • Effect of antibiotic therapy on human fecal microbiota and the relation to the development of Clostridium difficile
    • de La Cochetiere, M. F.; Durand, T.; Lalande, V.; Petit, J. C.; Potel, G.; Beaugerie, L. Effect of antibiotic therapy on human fecal microbiota and the relation to the development of Clostridium difficile. Microb. Ecol., 2008, 56 (3), 395-402.
    • (2008) Microb. Ecol , vol.56 , Issue.3 , pp. 395-402
    • de la Cochetiere, M.F.1    Durand, T.2    Lalande, V.3    Petit, J.C.4    Potel, G.5    Beaugerie, L.6
  • 47
    • 0034252293 scopus 로고    scopus 로고
    • Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteria
    • Ayabe, T.; Satchell, D. P.; Wilson, C. L.; Parks, W. C.; Selsted, M. E.; Ouellette, A. J. Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteria. Nat. Immunol., 2000, 1 (2), 113-118.
    • (2000) Nat Immunol , vol.1 , Issue.2 , pp. 113-118
    • Ayabe, T.1    Satchell, D.P.2    Wilson, C.L.3    Parks, W.C.4    Selsted, M.E.5    Ouellette, A.J.6
  • 48
    • 58549111588 scopus 로고    scopus 로고
    • Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface
    • Vaishnava, S.; Behrendt, C. L.; Ismail, A. S.; Eckmann, L.; Hooper, L. V. Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface. Proc. Natl. Acad. Sci. U. S. A, 2008, 105 (52), 20858-20863.
    • (2008) Proc. Natl. Acad. Sci. U. S. A , vol.105 , Issue.52 , pp. 20858-20863
    • Vaishnava, S.1    Behrendt, C.L.2    Ismail, A.S.3    Eckmann, L.4    Hooper, L.V.5
  • 49
    • 84886795788 scopus 로고    scopus 로고
    • Microbiota-mediated colonization resistance against intestinal pathogens
    • Buffie, C. G.; Pamer, E. G. Microbiota-mediated colonization resistance against intestinal pathogens. Nat. Rev. Immunol., 2013, 13 (11), 790-801.
    • (2013) Nat. Rev. Immunol , vol.13 , Issue.11 , pp. 790-801
    • Buffie, C.G.1    Pamer, E.G.2
  • 50
    • 84861972274 scopus 로고    scopus 로고
    • Regulated virulence controls the ability of a pathogen to compete with the gut microbiota
    • Kamada, N.; Kim, Y. G.; Sham, H. P.; Vallance, B. A.; Puente, J. L.; Martens, E. C.; Nunez, G. Regulated virulence controls the ability of a pathogen to compete with the gut microbiota. Science, 2012, 336 (6086), 1325-1329.
    • (2012) Science , vol.336 , Issue.6086 , pp. 1325-1329
    • Kamada, N.1    Kim, Y.G.2    Sham, H.P.3    Vallance, B.A.4    Puente, J.L.5    Martens, E.C.6    Nunez, G.7
  • 51
    • 33748039462 scopus 로고    scopus 로고
    • Symbiotic bacteria direct expression of an intestinal bactericidal lectin
    • Cash, H. L.; Whitham, C. V.; Behrendt, C. L.; Hooper, L. V. Symbiotic bacteria direct expression of an intestinal bactericidal lectin. Science, 2006, 313 (5790), 1126-1130.
    • (2006) Science , vol.313 , Issue.5790 , pp. 1126-1130
    • Cash, H.L.1    Whitham, C.V.2    Behrendt, C.L.3    Hooper, L.V.4
  • 52
    • 80054122238 scopus 로고    scopus 로고
    • The antibacterial lectin RegIIIgamma promotes the spatial segregation of microbiota and host in the intestine
    • Vaishnava, S.; Yamamoto, M.; Severson, K. M.; Ruhn, K. A.; Yu, X.; Koren, O.; Ley, R.; Wakeland, E. K.; Hooper, L. V. The antibacterial lectin RegIIIgamma promotes the spatial segregation of microbiota and host in the intestine. Science, 2011, 334 (6053), 255-258.
    • (2011) Science , vol.334 , Issue.6053 , pp. 255-258
    • Vaishnava, S.1    Yamamoto, M.2    Severson, K.M.3    Ruhn, K.A.4    Yu, X.5    Koren, O.6    Ley, R.7    Wakeland, E.K.8    Hooper, L.V.9
  • 53
    • 34547762705 scopus 로고    scopus 로고
    • MyD88-mediated signals induce the bactericidal lectin RegIII gamma and protect mice against intestinal Listeria monocytogenes infection
    • Brandl, K.; Plitas, G.; Schnabl, B.; DeMatteo, R. P.; Pamer, E. G. MyD88-mediated signals induce the bactericidal lectin RegIII gamma and protect mice against intestinal Listeria monocytogenes infection. J. Exp. Med., 2007, 204 (8), 1891-1900.
    • (2007) J. Exp. Med , vol.204 , Issue.8 , pp. 1891-1900
    • Brandl, K.1    Plitas, G.2    Schnabl, B.3    Dematteo, R.P.4    Pamer, E.G.5
  • 58
    • 79960843789 scopus 로고    scopus 로고
    • Helicobacter pylori infection prevents allergic asthma in mouse models through the induction of regulatory T cells
    • Arnold, I. C.; Dehzad, N.; Reuter, S.; Martin, H.; Becher, B.; Taube, C.; Muller, A. Helicobacter pylori infection prevents allergic asthma in mouse models through the induction of regulatory T cells. J. Clin. Invest., 2011, 121 (8), 3088-3093.
    • (2011) J. Clin. Invest , vol.121 , Issue.8 , pp. 3088-3093
    • Arnold, I.C.1    Dehzad, N.2    Reuter, S.3    Martin, H.4    Becher, B.5    Taube, C.6    Muller, A.7
  • 59
    • 0035554904 scopus 로고    scopus 로고
    • Sex differences in autoimmune disease
    • Whitacre, C. C. Sex differences in autoimmune disease. Nat. Immunol., 2001, 2 (9), 777-780.
    • (2001) Nat. Immunol , vol.2 , Issue.9 , pp. 777-780
    • Whitacre, C.C.1
  • 62
    • 0026536483 scopus 로고
    • Androgen treatment prevents diabetes in nonobese diabetic mice
    • Fox, H. S. Androgen treatment prevents diabetes in nonobese diabetic mice. J. Exp. Med., 1992, 175 (5), 1409-1412.
    • (1992) J. Exp. Med , vol.175 , Issue.5 , pp. 1409-1412
    • Fox, H.S.1
  • 63
    • 0019550128 scopus 로고
    • Effect of castration on the appearance of diabetes in NOD mouse
    • Makino, S.; Kunimoto, K.; Muraoka, Y.; Katagiri, K. Effect of castration on the appearance of diabetes in NOD mouse. Jikken Dobutsu, 1981, 30 (2), 137-140.
    • (1981) Jikken Dobutsu , vol.30 , Issue.2 , pp. 137-140
    • Makino, S.1    Kunimoto, K.2    Muraoka, Y.3    Katagiri, K.4
  • 65
    • 79952142398 scopus 로고    scopus 로고
    • The incidence of type-1 diabetes in NOD mice is modulated by restricted flora not germ-free conditions
    • King, C.; Sarvetnick, N. The incidence of type-1 diabetes in NOD mice is modulated by restricted flora not germ-free conditions. PLoS One, 2011, 6 (2), e17049
    • (2011) PLoS One , vol.6 , Issue.2
    • King, C.1    Sarvetnick, N.2
  • 66
    • 0027314785 scopus 로고
    • Complete Freund's adjuvant-induced T cells prevent the development and adoptive transfer of diabetes in nonobese diabetic mice
    • Qin, H. Y.; Sadelain, M. W.; Hitchon, C.; Lauzon, J.; Singh, B. Complete Freund's adjuvant-induced T cells prevent the development and adoptive transfer of diabetes in nonobese diabetic mice. J. Immunol., 1993, 150 (5), 2072-2080.
    • (1993) J. Immunol , vol.150 , Issue.5 , pp. 2072-2080
    • Qin, H.Y.1    Sadelain, M.W.2    Hitchon, C.3    Lauzon, J.4    Singh, B.5
  • 67
    • 10844224524 scopus 로고    scopus 로고
    • In vivo apoptosis of diabetogenic T cells in NOD mice by IFN-gamma/TNF-alpha
    • Qin, H. Y.; Chaturvedi, P.; Singh, B. In vivo apoptosis of diabetogenic T cells in NOD mice by IFN-gamma/TNF-alpha. Int. Immunol., 2004, 16 (12), 1723-1732.
    • (2004) Int. Immunol , vol.16 , Issue.12 , pp. 1723-1732
    • Qin, H.Y.1    Chaturvedi, P.2    Singh, B.3
  • 68
    • 0035863721 scopus 로고    scopus 로고
    • Th1 to Th2 cytokine shifts in nonobese diabetic mice: Sometimes an outcome, rather than the cause, of diabetes resistance elicited by immunostimulation
    • Serreze, D. V.; Chapman, H. D.; Post, C. M.; Johnson, E. A.; Suarez-Pinzon, W. L.; Rabinovitch, A. Th1 to Th2 cytokine shifts in nonobese diabetic mice: sometimes an outcome, rather than the cause, of diabetes resistance elicited by immunostimulation. J. Immunol., 2001, 166 (2), 1352-1359.
    • (2001) J. Immunol , vol.166 , Issue.2 , pp. 1352-1359
    • Serreze, D.V.1    Chapman, H.D.2    Post, C.M.3    Johnson, E.A.4    Suarez-Pinzon, W.L.5    Rabinovitch, A.6
  • 69
    • 80054698474 scopus 로고    scopus 로고
    • Immunomodulation and regeneration of islet Beta cells by cytokines in autoimmune type 1 diabetes
    • Singh, B.; Nikoopour, E.; Huszarik, K.; Elliott, J. F.; Jevnikar, A. M. Immunomodulation and regeneration of islet Beta cells by cytokines in autoimmune type 1 diabetes. J. Interferon Cytokine Res., 2011, 31 (10), 711-719.
    • (2011) J. Interferon Cytokine Res , vol.31 , Issue.10 , pp. 711-719
    • Singh, B.1    Nikoopour, E.2    Huszarik, K.3    Elliott, J.F.4    Jevnikar, A.M.5
  • 70
    • 0036849492 scopus 로고    scopus 로고
    • Gamma interferon paradoxically inhibits the development of diabetes in the NOD mouse
    • Sobel, D. O.; Han, J.; Williams, J.; Yoon, J. W.; Jun, H. S.; Ahvazi, B. Gamma interferon paradoxically inhibits the development of diabetes in the NOD mouse. J. Autoimmun., 2002, 19 (3), 129-137.
    • (2002) J. Autoimmun , vol.19 , Issue.3 , pp. 129-137
    • Sobel, D.O.1    Han, J.2    Williams, J.3    Yoon, J.W.4    Jun, H.S.5    Ahvazi, B.6
  • 73
    • 84877839153 scopus 로고    scopus 로고
    • IL-22 deficiency alters colonic microbiota to be transmissible and colitogenic
    • Zenewicz, L. A.; Yin, X.; Wang, G.; Elinav, E.; Hao, L.; Zhao, L.; Flavell, R. A. IL-22 deficiency alters colonic microbiota to be transmissible and colitogenic. J. Immunol., 2013, 190 (10), 5306-5312.
    • (2013) J. Immunol , vol.190 , Issue.10 , pp. 5306-5312
    • Zenewicz, L.A.1    Yin, X.2    Wang, G.3    Elinav, E.4    Hao, L.5    Zhao, L.6    Flavell, R.A.7
  • 74
    • 77954518232 scopus 로고    scopus 로고
    • Th17 polarized cells from nonobese diabetic mice following mycobacterial adjuvant immunotherapy delay type 1 diabetes
    • Nikoopour, E.; Schwartz, J. A.; Huszarik, K.; Sandrock, C.; Krougly, O.; Lee-Chan, E.; Singh, B. Th17 polarized cells from nonobese diabetic mice following mycobacterial adjuvant immunotherapy delay type 1 diabetes. J. Immunol., 2010, 184 (9), 4779-4788.
    • (2010) J. Immunol , vol.184 , Issue.9 , pp. 4779-4788
    • Nikoopour, E.1    Schwartz, J.A.2    Huszarik, K.3    Sandrock, C.4    Krougly, O.5    Lee-Chan, E.6    Singh, B.7
  • 75
    • 84855375911 scopus 로고    scopus 로고
    • IL-17 silencing does not protect nonobese diabetic mice from autoimmune diabetes
    • Joseph, J.; Bittner, S.; Kaiser, F. M.; Wiendl, H.; Kissler, S. IL-17 silencing does not protect nonobese diabetic mice from autoimmune diabetes. J. Immunol., 2012, 188 (1), 216-221.
    • (2012) J. Immunol , vol.188 , Issue.1 , pp. 216-221
    • Joseph, J.1    Bittner, S.2    Kaiser, F.M.3    Wiendl, H.4    Kissler, S.5
  • 76
    • 77953302950 scopus 로고    scopus 로고
    • Inflammatory tendencies and overproduction of IL-17 in the colon of young NOD mice are counteracted with diet change
    • Alam, C.; Valkonen, S.; Palagani, V.; Jalava, J.; Eerola, E.; Hanninen, A. Inflammatory tendencies and overproduction of IL-17 in the colon of young NOD mice are counteracted with diet change. Diabetes, 2010, 59 (9), 2237-2246.
    • (2010) Diabetes , vol.59 , Issue.9 , pp. 2237-2246
    • Alam, C.1    Valkonen, S.2    Palagani, V.3    Jalava, J.4    Eerola, E.5    Hanninen, A.6
  • 77
    • 80052517464 scopus 로고    scopus 로고
    • Effects of a germ-free environment on gut immune regulation and diabetes progression in non-obese diabetic (NOD) mice
    • Alam, C.; Bittoun, E.; Bhagwat, D.; Valkonen, S.; Saari, A.; Jaakkola, U.; Eerola, E.; Huovinen, P.; Hanninen, A. Effects of a germ-free environment on gut immune regulation and diabetes progression in non-obese diabetic (NOD) mice. Diabetologia, 2011, 54 (6), 1398-1406.
    • (2011) Diabetologia , vol.54 , Issue.6 , pp. 1398-1406
    • Alam, C.1    Bittoun, E.2    Bhagwat, D.3    Valkonen, S.4    Saari, A.5    Jaakkola, U.6    Eerola, E.7    Huovinen, P.8    Hanninen, A.9
  • 79
    • 35348857386 scopus 로고    scopus 로고
    • Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases
    • Frank, D. N.; St Amand, A. L.; Feldman, R. A.; Boedeker, E. C.; Harpaz, N.; Pace, N. R. Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases. Proc. Natl. Acad. Sci. U. S. A, 2007, 104 (34), 13780-13785.
    • (2007) Proc. Natl. Acad. Sci. U. S. A , vol.104 , Issue.34 , pp. 13780-13785
    • Frank, D.N.1    St Amand, A.L.2    Feldman, R.A.3    Boedeker, E.C.4    Harpaz, N.5    Pace, N.R.6
  • 85
    • 84893859801 scopus 로고    scopus 로고
    • The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition
    • Chang, P. V.; Hao, L.; Offermanns, S.; Medzhitov, R. The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition. Proc. Natl. Acad. Sci. U. S. A, 2014, 111(6), 2247-52.
    • (2014) Proc. Natl. Acad. Sci. U. S. A , vol.111 , Issue.6 , pp. 2247-2252
    • Chang, P.V.1    Hao, L.2    Offermanns, S.3    Medzhitov, R.4
  • 86
    • 77950002937 scopus 로고    scopus 로고
    • The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis
    • Zaki, M. H.; Boyd, K. L.; Vogel, P.; Kastan, M. B.; Lamkanfi, M.; Kanneganti, T. D. The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis. Immunity, 2010, 32 (3), 379-391.
    • (2010) Immunity , vol.32 , Issue.3 , pp. 379-391
    • Zaki, M.H.1    Boyd, K.L.2    Vogel, P.3    Kastan, M.B.4    Lamkanfi, M.5    Kanneganti, T.D.6
  • 90
    • 33747114270 scopus 로고    scopus 로고
    • Role of toll-like receptors in spontaneous commensal-dependent colitis
    • Rakoff-Nahoum, S.; Hao, L.; Medzhitov, R. Role of toll-like receptors in spontaneous commensal-dependent colitis. Immunity., 2006, 25 (2), 319-329.
    • (2006) Immunity , vol.25 , Issue.2 , pp. 319-329
    • Rakoff-Nahoum, S.1    Hao, L.2    Medzhitov, R.3
  • 98
    • 77954827808 scopus 로고    scopus 로고
    • Induction of a regulatory B cell population in experimental allergic encephalomyelitis by alteration of the gut commensal microflora
    • Ochoa-Reparaz, J.; Mielcarz, D. W.; Haque-Begum, S.; Kasper, L. H. Induction of a regulatory B cell population in experimental allergic encephalomyelitis by alteration of the gut commensal microflora. Gut Microbes., 2010, 1 (2), 103-108.
    • (2010) Gut Microbes , vol.1 , Issue.2 , pp. 103-108
    • Ochoa-Reparaz, J.1    Mielcarz, D.W.2    Haque-Begum, S.3    Kasper, L.H.4
  • 99
    • 77749322389 scopus 로고    scopus 로고
    • A novel probiotic mixture exerts a therapeutic effect on experimental autoimmune encephalomyelitis mediated by IL-10 producing regulatory T cells
    • Lavasani, S.; Dzhambazov, B.; Nouri, M.; Fak, F.; Buske, S.; Molin, G.; Thorlacius, H.; Alenfall, J.; Jeppsson, B.; Westrom, B. A novel probiotic mixture exerts a therapeutic effect on experimental autoimmune encephalomyelitis mediated by IL-10 producing regulatory T cells. PLoS One, 2010, 5 (2), e9009
    • (2010) PLoS One , vol.5 , Issue.2
    • Lavasani, S.1    Dzhambazov, B.2    Nouri, M.3    Fak, F.4    Buske, S.5    Molin, G.6    Thorlacius, H.7    Alenfall, J.8    Jeppsson, B.9    Westrom, B.10
  • 100
    • 58749099141 scopus 로고    scopus 로고
    • Mycobacterium bovis bacille Calmette-Guerin infection in the CNS suppresses experimental autoimmune encephalomyelitis and Th17 responses in an IFN-gamma-independent manner
    • Lee, J.; Reinke, E. K.; Zozulya, A. L.; Sandor, M.; Fabry, Z. Mycobacterium bovis bacille Calmette-Guerin infection in the CNS suppresses experimental autoimmune encephalomyelitis and Th17 responses in an IFN-gamma-independent manner. J. Immunol., 2008, 181 (9), 6201-6212.
    • (2008) J. Immunol , vol.181 , Issue.9 , pp. 6201-6212
    • Lee, J.1    Reinke, E.K.2    Zozulya, A.L.3    Sandor, M.4    Fabry, Z.5
  • 103
    • 84860118160 scopus 로고    scopus 로고
    • Loss of sex and age driven differences in the gut microbiome characterize arthritis-susceptible 0401 mice but not arthritis-resistant 0402 mice
    • Gomez, A.; Luckey, D.; Yeoman, C. J.; Marietta, E. V.; Berg Miller, M. E.; Murray, J. A.; White, B. A.; Taneja, V. Loss of sex and age driven differences in the gut microbiome characterize arthritis-susceptible 0401 mice but not arthritis-resistant 0402 mice. PLoS One, 2012, 7 (4), e36095
    • (2012) PLoS One , vol.7 , Issue.4
    • Gomez, A.1    Luckey, D.2    Yeoman, C.J.3    Marietta, E.V.4    Berg Miller, M.E.5    Murray, J.A.6    White, B.A.7    Taneja, V.8
  • 104
    • 84866146940 scopus 로고    scopus 로고
    • Diversity, stability and resilience of the human gut microbiota
    • Lozupone, C. A.; Stombaugh, J. I.; Gordon, J. I.; Jansson, J. K.; Knight, R. Diversity, stability and resilience of the human gut microbiota. Nature, 2012, 489 (7415), 220-230.
    • (2012) Nature , vol.489 , Issue.7415 , pp. 220-230
    • Lozupone, C.A.1    Stombaugh, J.I.2    Gordon, J.I.3    Jansson, J.K.4    Knight, R.5
  • 108
    • 41849127118 scopus 로고    scopus 로고
    • Dietinduced obesity is linked to marked but reversible alterations in the mouse distal gut microbiome
    • Turnbaugh, P. J.; Backhed, F.; Fulton, L.; Gordon, J. I. Dietinduced obesity is linked to marked but reversible alterations in the mouse distal gut microbiome. Cell Host Microbe, 2008, 3 (4), 213-223.
    • (2008) Cell Host Microbe , vol.3 , Issue.4 , pp. 213-223
    • Turnbaugh, P.J.1    Backhed, F.2    Fulton, L.3    Gordon, J.I.4
  • 113
    • 33845901507 scopus 로고    scopus 로고
    • Microbial ecology: Human gut microbes associated with obesity
    • Ley, R. E.; Turnbaugh, P. J.; Klein, S.; Gordon, J. I. Microbial ecology: human gut microbes associated with obesity. Nature, 2006, 444 (7122), 1022-1023.
    • (2006) Nature , vol.444 , Issue.7122 , pp. 1022-1023
    • Ley, R.E.1    Turnbaugh, P.J.2    Klein, S.3    Gordon, J.I.4
  • 114
    • 33845874101 scopus 로고    scopus 로고
    • An obesity-associated gut microbiome with increased capacity for energy harvest
    • Turnbaugh, P. J.; Ley, R. E.; Mahowald, M. A.; Magrini, V.; Mardis, E. R.; Gordon, J. I. An obesity-associated gut microbiome with increased capacity for energy harvest. Nature, 2006, 444 (7122), 1027-1031.
    • (2006) Nature , vol.444 , Issue.7122 , pp. 1027-1031
    • Turnbaugh, P.J.1    Ley, R.E.2    Mahowald, M.A.3    Magrini, V.4    Mardis, E.R.5    Gordon, J.I.6
  • 116
    • 78650547540 scopus 로고    scopus 로고
    • An endogenous aryl hydrocarbon receptor ligand acts on dendritic cells and T cells to suppress experimental autoimmune encephalomyelitis
    • Quintana, F. J.; Murugaiyan, G.; Farez, M. F.; Mitsdoerffer, M.; Tukpah, A. M.; Burns, E. J.; Weiner, H. L. An endogenous aryl hydrocarbon receptor ligand acts on dendritic cells and T cells to suppress experimental autoimmune encephalomyelitis. Proc. Natl. Acad. Sci. U. S. A, 2010, 107 (48), 20768-20773.
    • (2010) Proc. Natl. Acad. Sci. U. S. A , vol.107 , Issue.48 , pp. 20768-20773
    • Quintana, F.J.1    Murugaiyan, G.2    Farez, M.F.3    Mitsdoerffer, M.4    Tukpah, A.M.5    Burns, E.J.6    Weiner, H.L.7
  • 117
    • 84893582941 scopus 로고    scopus 로고
    • Low incidence of spontaneous type 1 diabetes in non-obese diabetic mice raised on gluten-free diets is associated with changes in the intestinal microbiome
    • Marietta, E. V.; Gomez, A. M.; Yeoman, C.; Tilahun, A. Y.; Clark, C. R.; Luckey, D. H.; Murray, J. A.; White, B. A.; Kudva, Y. C.; Rajagopalan, G. Low incidence of spontaneous type 1 diabetes in non-obese diabetic mice raised on gluten-free diets is associated with changes in the intestinal microbiome. PLoS One, 2013, 8 (11), e78687
    • (2013) PLoS One , vol.8 , Issue.11
    • Marietta, E.V.1    Gomez, A.M.2    Yeoman, C.3    Tilahun, A.Y.4    Clark, C.R.5    Luckey, D.H.6    Murray, J.A.7    White, B.A.8    Kudva, Y.C.9    Rajagopalan, G.10
  • 118
    • 84893089832 scopus 로고    scopus 로고
    • pH of drinking water influences the composition of gut microbiome and type 1 diabetes incidence
    • Sofi, M. H.; Gudi, R. R.; Karumuthil-Melethil, S.; Perez, N.; Johnson, B. M.; Vasu, C. pH of drinking water influences the composition of gut microbiome and type 1 diabetes incidence. Diabetes, 2014, 63(2), 632-44.
    • (2014) Diabetes , vol.63 , Issue.2 , pp. 632-644
    • Sofi, M.H.1    Gudi, R.R.2    Karumuthil-Melethil, S.3    Perez, N.4    Johnson, B.M.5    Vasu, C.6
  • 121
    • 84882668842 scopus 로고    scopus 로고
    • Group 3 innate lymphoid cells inhibit T-cellmediated intestinal inflammation through aryl hydrocarbon receptor signaling and regulation of microflora
    • Qiu, J.; Guo, X.; Chen, Z. M.; He, L.; Sonnenberg, G. F.; Artis, D.; Fu, Y. X.; Zhou, L. Group 3 innate lymphoid cells inhibit T-cellmediated intestinal inflammation through aryl hydrocarbon receptor signaling and regulation of microflora. Immunity, 2013, 39 (2), 386-399.
    • (2013) Immunity , vol.39 , Issue.2 , pp. 386-399
    • Qiu, J.1    Guo, X.2    Chen, Z.M.3    He, L.4    Sonnenberg, G.F.5    Artis, D.6    Fu, Y.X.7    Zhou, L.8
  • 125
    • 57349098169 scopus 로고    scopus 로고
    • Protective effects of Lactobacillus rhamnosus[corrected] and Bifidobacterium infantis in murine models for colitis do not involve the vagus nerve
    • van der, K. H.; O'Mahony, C.; Shanahan, F.; O'Mahony, L.; Bienenstock, J. Protective effects of Lactobacillus rhamnosus[corrected] and Bifidobacterium infantis in murine models for colitis do not involve the vagus nerve. Am. J. Physiol. Regul. Integr. Comp. Physiol., 2008, 295 (4), R1131-R1137-R1137.
    • (2008) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.295 , Issue.4 , pp. 1131-1137
    • van der, K.H.1    O'Mahony, C.2    Shanahan, F.3    O'Mahony, L.4    Bienenstock, J.5
  • 127
    • 84892482218 scopus 로고    scopus 로고
    • Guidance on preparing an investigational new drug application for fecal microbiota transplantation studies
    • Kelly, C. R.; Kunde, S. S.; Khoruts, A. Guidance on preparing an investigational new drug application for fecal microbiota transplantation studies. Clin. Gastroenterol. Hepatol., 2014, 12(2), 283-8.
    • (2014) Clin. Gastroenterol. Hepatol , vol.12 , Issue.2 , pp. 283-288
    • Kelly, C.R.1    Kunde, S.S.2    Khoruts, A.3


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