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Volumn 16, Issue 12, 2004, Pages 1723-1732

In vivo apoptosis of diabetogenic T cells in NOD mice by IFN-γ/TNF-α

Author keywords

Apoptosis; BCG; Cytokines; Immunoregulation; Mycobacterium; NOD mice; Type 1 diabetes

Indexed keywords

BCG VACCINE; CYTOKINE ANTIBODY; FAS ANTIGEN; FAS LIGAND; FREUND ADJUVANT; GAMMA INTERFERON; INTERLEUKIN 4; NEUTRALIZING ANTIBODY; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR;

EID: 10844224524     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/dxh173     Document Type: Article
Times cited : (61)

References (49)
  • 1
    • 0025293535 scopus 로고
    • Prevention of type I diabetes in NOD mice by adjuvant immunotherapy
    • Sadelain, M. W. J., Qin, H.-Y., Lauzon, J. and Singh, B. 1990. Prevention of type I diabetes in NOD mice by adjuvant immunotherapy. Diabetes 39:583.
    • (1990) Diabetes , vol.39 , pp. 583
    • Sadelain, M.W.J.1    Qin, H.-Y.2    Lauzon, J.3    Singh, B.4
  • 4
    • 0031171726 scopus 로고    scopus 로고
    • BCG Vaccination Prevents Insulin-Dependent Diabetes Mellitus (IDDM) in NOD Mice after Disease Acceleration with Cyclophosphamide
    • Qin, H.-Y. and Singh, B. 1997. BCG Vaccination Prevents Insulin-Dependent Diabetes Mellitus (IDDM) in NOD Mice after Disease Acceleration with Cyclophosphamide. J. Autoimmunity 10:271.
    • (1997) J. Autoimmunity , vol.10 , pp. 271
    • Qin, H.-Y.1    Singh, B.2
  • 5
    • 0026559333 scopus 로고
    • AT cells dominant state in the autoimmune process of nonobese diabetic mice treated with complete Freund's adjuvant
    • Ulaeto, D., Lacy, P. E., Kipnis, D. M., Kanagawa, O. and Unanue, E. R. 1992. AT cells dominant state in the autoimmune process of nonobese diabetic mice treated with complete Freund's adjuvant. Proc. Natl Acad. Sci. USA 89:3927.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 3927
    • Ulaeto, D.1    Lacy, P.E.2    Kipnis, D.M.3    Kanagawa, O.4    Unanue, E.R.5
  • 6
    • 0026502893 scopus 로고
    • Prevention of recurrence of IDDM in islet-transplanted diabetic NOD mice by adjuvant immunotherapy
    • Wang, T., Singh, B., Warnock, G. L. and Rajotte R. V. 1992. Prevention of recurrence of IDDM in islet-transplanted diabetic NOD mice by adjuvant immunotherapy. Diabetes 41:114.
    • (1992) Diabetes , vol.41 , pp. 114
    • Wang, T.1    Singh, B.2    Warnock, G.L.3    Rajotte, R.V.4
  • 7
    • 0028348582 scopus 로고
    • BCG immunotherapy prevents recurrence of diabetes in islet grafts transplanted into spontaneously diabetic NOD mice
    • Lakey, J. R., Singh, B., Warnock, G. L. and Rajotte R. V. 1994. BCG immunotherapy prevents recurrence of diabetes in islet grafts transplanted into spontaneously diabetic NOD mice. Transplantation 57:1213.
    • (1994) Transplantation , vol.57 , pp. 1213
    • Lakey, J.R.1    Singh, B.2    Warnock, G.L.3    Rajotte, R.V.4
  • 8
    • 0027314785 scopus 로고
    • Complete Freund's adjuvant-induced T cells prevent the development and adoptive transfer diabetes in nonobese diabetic mice
    • Qin, H.-Y., Sadelain, M. W. J., Hichon, C., Lauzon, J. and Singh, B. 1993. Complete Freund's adjuvant-induced T cells prevent the development and adoptive transfer diabetes in nonobese diabetic mice. J. Immunol. 150:80.
    • (1993) J. Immunol. , vol.150 , pp. 80
    • Qin, H.-Y.1    Sadelain, M.W.J.2    Hichon, C.3    Lauzon, J.4    Singh, B.5
  • 10
    • 0028989087 scopus 로고
    • IFN-γ gene expression in pancreatic islet-infiltrating mononuclear cells correlates with autoimmune diabetes in nonobese diabetic mice
    • Rabinovitch, A., Suarez-Pinzon, W. L., Sorensen, O., Bleackley, R. C. and Power R. F. 1995. IFN-γ gene expression in pancreatic islet-infiltrating mononuclear cells correlates with autoimmune diabetes in nonobese diabetic mice. J. Immunol. 154:4874.
    • (1995) J. Immunol. , vol.154 , pp. 4874
    • Rabinovitch, A.1    Suarez-Pinzon, W.L.2    Sorensen, O.3    Bleackley, R.C.4    Power, R.F.5
  • 11
    • 0028095152 scopus 로고
    • Analysis of cytokine mRNA expression in syngeneic islet graft of NOD mice: Interleukin 2 and interferon γ mRNA expression correlate with graft rejection and interleukin 10 with graft survival
    • Rabinovitch, A. Sorensen, O., Suarez-Pinzon, W. L., Power, R. F., Rajotte, R. V. and Bleackley, R. C. 1994. Analysis of cytokine mRNA expression in syngeneic islet graft of NOD mice: interleukin 2 and interferon γ mRNA expression correlate with graft rejection and interleukin 10 with graft survival. Diabetologia 37:833.
    • (1994) Diabetologia , vol.37 , pp. 833
    • Rabinovitch, A.1    Sorensen, O.2    Suarez-Pinzon, W.L.3    Power, R.F.4    Rajotte, R.V.5    Bleackley, R.C.6
  • 12
    • 0032414556 scopus 로고    scopus 로고
    • Endogenous immune response to glutamic acid decarboxylase (GAD67) in NOD mice is modulated by adjuvant immunotherapy
    • Qin, H.-Y., Elliott, J. F., Lakey, J. R., Rajotte, R. V. and Singh, B. 1998. Endogenous immune response to glutamic acid decarboxylase (GAD67) in NOD mice is modulated by adjuvant immunotherapy. J. Autoimmunity 11:591.
    • (1998) J. Autoimmunity , vol.11 , pp. 591
    • Qin, H.-Y.1    Elliott, J.F.2    Lakey, J.R.3    Rajotte, R.V.4    Singh, B.5
  • 13
    • 0035863721 scopus 로고    scopus 로고
    • Th1 to Th2 cytokines shifts in Nonobese diabetic mice: Sometimes an outcome, rather than the cause, of diabetes resistance elicited by immunostimulation
    • Serreze, D. V., Chapman, H. D., Post, C. M., Johnson, E. A., Suarez-Pinzon, W. L. and Rabinovitch, A. 2001. Th1 to Th2 cytokines shifts in Nonobese diabetic mice: sometimes an outcome, rather than the cause, of diabetes resistance elicited by immunostimulation. J. Immunol. 166:1352.
    • (2001) J. Immunol. , vol.166 , pp. 1352
    • Serreze, D.V.1    Chapman, H.D.2    Post, C.M.3    Johnson, E.A.4    Suarez-Pinzon, W.L.5    Rabinovitch, A.6
  • 14
    • 0029891231 scopus 로고    scopus 로고
    • Activation of an interleukin-4 mRNA-producing population of peripheral blood mononuclear cells after infection with mycobacterium bovis or vaccination with killed, but not live BCG
    • Hooks, G., Mackintosh. C. and Buchan, G. 1996. Activation of an interleukin-4 mRNA-producing population of peripheral blood mononuclear cells after infection with mycobacterium bovis or vaccination with killed, but not live BCG. Immunology 88:269.
    • (1996) Immunology , vol.88 , pp. 269
    • Hooks, G.1    Mackintosh, C.2    Buchan, G.3
  • 15
    • 0025316338 scopus 로고
    • Strain differences in mouse cellular response to mycobacterium lepraemurium and BCG subcutaneous infections. I. Analysis of cell surface phenotype in local granulomas
    • Roch, F. and Bach, M. A. 1990. Strain differences in mouse cellular response to mycobacterium lepraemurium and BCG subcutaneous infections. I. Analysis of cell surface phenotype in local granulomas. Exp. Immunol. 80:332.
    • (1990) Exp. Immunol. , vol.80 , pp. 332
    • Roch, F.1    Bach, M.A.2
  • 17
    • 0027236482 scopus 로고
    • Cytokine secretion by CD4 T lymphocytes acquired in response to mycobacterium tuberculosis infection
    • Orme, I. M., Roberts, A. D., Griffin, J. P. and Abrams, J. S. 1993. Cytokine secretion by CD4 T lymphocytes acquired in response to mycobacterium tuberculosis infection. J. Immunol. 151:518.
    • (1993) J. Immunol. , vol.151 , pp. 518
    • Orme, I.M.1    Roberts, A.D.2    Griffin, J.P.3    Abrams, J.S.4
  • 18
    • 0034600788 scopus 로고    scopus 로고
    • Interferon γ eliminates responding CD4 T cells during mycobacterial infection by inducing apoptosis of activated CD4 T cells
    • Dalton, D. K., Haynes, L., Chu, C.-Q., Swain, S. L. and Wittmer, S. 2000. Interferon γ eliminates responding CD4 T cells during mycobacterial infection by inducing apoptosis of activated CD4 T cells. J. Exp. Med. 192:117.
    • (2000) J. Exp. Med. , vol.192 , pp. 117
    • Dalton, D.K.1    Haynes, L.2    Chu, C.-Q.3    Swain, S.L.4    Wittmer, S.5
  • 19
    • 0036849492 scopus 로고    scopus 로고
    • Gamma interferon paradoxically inhibits the development of diabetes in the NOD mice
    • Sobel, D. O., Han, J., Williams, J., Yoon, J.-W., Jun, H.-S. and Ahvazi, B. 2002. Gamma interferon paradoxically inhibits the development of diabetes in the NOD mice. J. Autoimmunity 19:129.
    • (2002) J. Autoimmunity , vol.19 , pp. 129
    • Sobel, D.O.1    Han, J.2    Williams, J.3    Yoon, J.-W.4    Jun, H.-S.5    Ahvazi, B.6
  • 20
    • 0034601012 scopus 로고    scopus 로고
    • Failure to suppress the expansion of the activated CD4 T cell population in interferon γ-deficient mice leads to exacerbation of experimental autoimmune encephalomyelitis. J
    • Chu, C.-Q., Wittmer, S. and Dalton, D. K. 2000. Failure to suppress the expansion of the activated CD4 T cell population in interferon γ-deficient mice leads to exacerbation of experimental autoimmune encephalomyelitis. J. Exp. Med. 191:123.
    • (2000) Exp. Med. , vol.191 , pp. 123
    • Chu, C.-Q.1    Wittmer, S.2    Dalton, D.K.3
  • 22
    • 0034939166 scopus 로고    scopus 로고
    • Reversal of established autoimmune diabetes by restoration of endogenous beta cell function
    • Ryu, S., Kodama, S., Ryu, K. and Faustman, D. L. 2001. Reversal of established autoimmune diabetes by restoration of endogenous beta cell function. J. Clin. Invest. 108:63.
    • (2001) J. Clin. Invest. , vol.108 , pp. 63
    • Ryu, S.1    Kodama, S.2    Ryu, K.3    Faustman, D.L.4
  • 23
    • 0025020303 scopus 로고
    • Prevention of Diabetes in nonobese diabetic mice by tumor necrosis factor (TNF): Similarities between TNF-alpha and interleukin 1
    • Jacob, C. O., Aiso, S., Michie, S. A., McDevitt, H. O. and Acha-orbea, H. 1990. Prevention of Diabetes in nonobese diabetic mice by tumor necrosis factor (TNF): similarities between TNF-alpha and interleukin 1. Proc. Natl Acad. Sci. USA 87:968.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 968
    • Jacob, C.O.1    Aiso, S.2    Michie, S.A.3    McDevitt, H.O.4    Acha-Orbea, H.5
  • 24
    • 0025734694 scopus 로고
    • Reduction in insulitis following administration of IFN-γ and TNF-α in the NOD mice
    • Campbell, I. L., Oxbrow, L. and Harrison, L. C. 1991. Reduction in insulitis following administration of IFN-γ and TNF-α in the NOD mice. J. Autoimmunity 4:249.
    • (1991) J. Autoimmunity , vol.4 , pp. 249
    • Campbell, I.L.1    Oxbrow, L.2    Harrison, L.C.3
  • 25
    • 0035877181 scopus 로고    scopus 로고
    • A dual role for TNF-alpha in type 1 diabetes: Islet-specific expression abrogates the ongoing autoimmune process when induced late but not early during pathogenesis
    • Christen, U., Wolfe, T., Mohrle, U., Hughes, A. C., Rodrigo, E., Green, E. A., Flavell, R. A. and Herrath, M. G. 2001. A dual role for TNF-alpha in type 1 diabetes: islet-specific expression abrogates the ongoing autoimmune process when induced late but not early during pathogenesis. J. Immunol. 166:7023.
    • (2001) J. Immunol. , vol.166 , pp. 7023
    • Christen, U.1    Wolfe, T.2    Mohrle, U.3    Hughes, A.C.4    Rodrigo, E.5    Green, E.A.6    Flavell, R.A.7    Herrath, M.G.8
  • 28
    • 0028172588 scopus 로고
    • Differential ability of Th1 and Th2 cells to express Fas ligand and to undergo activation induced cell death
    • Ramsdell, F., Seaman, M. S., Robert, R. E., Picha, K. S., Kennedy, M. K. and Lynch, D. H. 1994. Differential ability of Th1 and Th2 cells to express Fas ligand and to undergo activation induced cell death. Int. Immunol. 6:1545.
    • (1994) Int. Immunol. , vol.6 , pp. 1545
    • Ramsdell, F.1    Seaman, M.S.2    Robert, R.E.3    Picha, K.S.4    Kennedy, M.K.5    Lynch, D.H.6
  • 30
    • 0030200829 scopus 로고    scopus 로고
    • The roles of Fas/APO-1 (CD95) and TNF in antigen-induced programmed cell death in T cell receptor transgenic mice
    • Sytwu, H.-K., Liblau, R. S. and McDevitt H. O. 1996. The roles of Fas/APO-1 (CD95) and TNF in antigen-induced programmed cell death in T cell receptor transgenic mice. Immunity 5:17.
    • (1996) Immunity , vol.5 , pp. 17
    • Sytwu, H.-K.1    Liblau, R.S.2    McDevitt, H.O.3
  • 31
    • 0026772456 scopus 로고
    • Mechanisms of Complete Freund's adjuvant protection against diabetes in BB rat: Induction of non-specific suppressor cells
    • Qin, H.-Y., Suarez-Pinzon, WL., Parfrey, N., Power RF. and Rabinovitch, A. 1992. Mechanisms of Complete Freund's adjuvant protection against diabetes in BB rat: Induction of non-specific suppressor cells. Autoimmunity 12:193.
    • (1992) Autoimmunity , vol.12 , pp. 193
    • Qin, H.-Y.1    Suarez-Pinzon, W.L.2    Parfrey, N.3    Power, R.F.4    Rabinovitch, A.5
  • 32
    • 0031423760 scopus 로고    scopus 로고
    • The nonobese diabetic mouse as a model of autoimmune diabetes: Immune dysregulation gets the NOD
    • Delovitch, T. and Singh, B. 1997. The nonobese diabetic mouse as a model of autoimmune diabetes: immune dysregulation gets the NOD. Immunity 7:727.
    • (1997) Immunity , vol.7 , pp. 727
    • Delovitch, T.1    Singh, B.2
  • 33
    • 0030068383 scopus 로고    scopus 로고
    • low CD4 cells correlated with cytokine profiles in spontaneously autoimmune diabetes mouse
    • low CD4 cells correlated with cytokine profiles in spontaneously autoimmune diabetes mouse. Diabetes 45:71.
    • (1996) Diabetes , vol.45 , pp. 71
    • Shimada, A.1    Rohane, P.2    Fathman, C.G.3    Charlton, B.4
  • 37
    • 0025999761 scopus 로고
    • Possible mechanism of preventative effect of BCG against diabetes mellitus in NOD mouse: I. Generation of suppressor macrophages in spleen cells of BCG-vaccinated mice
    • Yagi, H., Matsumoto, M., Suzuki, S., Misaki, R., Suzuki, R., Makino, S. and Harada, M. 1991. Possible mechanism of preventative effect of BCG against diabetes mellitus in NOD mouse: I. Generation of suppressor macrophages in spleen cells of BCG-vaccinated mice. Cell Immunol. 138:130.
    • (1991) Cell Immunol. , vol.138 , pp. 130
    • Yagi, H.1    Matsumoto, M.2    Suzuki, S.3    Misaki, R.4    Suzuki, R.5    Makino, S.6    Harada, M.7
  • 38
    • 1642454721 scopus 로고    scopus 로고
    • Regulation of autoimmune diabetes by complete Freund's adjuvant is mediated by NK cells
    • Lee, I.-F., Din, H., Trudeau, J., Dutz, J. and Tan, R. 2004. Regulation of autoimmune diabetes by complete Freund's adjuvant is mediated by NK cells. J. Immunol. 172:937.
    • (2004) J. Immunol. , vol.172 , pp. 937
    • Lee, I.-F.1    Din, H.2    Trudeau, J.3    Dutz, J.4    Tan, R.5
  • 40
    • 0027511113 scopus 로고
    • Neutralization of gamma interferon and tumor necrosis factor alpha blocks in vivo synthesis of nitrogen oxides from L-arginine and protection against Francislla tularensis infection in Mycobacterium bovis BCG-treated mice
    • Green, S. J., Nacy, C. A., Schreiber, R. D., Granger, D. L., Crawford, R. M., Meltzer, M. S. and Fortier, A. H. 1993. Neutralization of gamma interferon and tumor necrosis factor alpha blocks in vivo synthesis of nitrogen oxides from L-arginine and protection against Francislla tularensis infection in Mycobacterium bovis BCG-treated mice. Infect. Immun. 61:689.
    • (1993) Infect. Immun. , vol.61 , pp. 689
    • Green, S.J.1    Nacy, C.A.2    Schreiber, R.D.3    Granger, D.L.4    Crawford, R.M.5    Meltzer, M.S.6    Fortier, A.H.7
  • 41
    • 0037327274 scopus 로고    scopus 로고
    • Autoimmune islet destruction in apontaneous type 1 diabetes is not β-cell exclusive
    • Winer, S., Tsui, H., Lau, A. et al. 2003. Autoimmune islet destruction in apontaneous type 1 diabetes is not β-cell exclusive. Nature Med. 9:198.
    • (2003) Nature Med. , vol.9 , pp. 198
    • Winer, S.1    Tsui, H.2    Lau, A.3
  • 42
    • 0024464668 scopus 로고
    • High potential to tumor necrosis factor α (TNF-α) production of thyroid infiltrating lymphocytes in Hasimoto's thyroiditis: A peculiar feature of destructive thyroid autoimmunity
    • Del Prete, G. F., Tiri, A., De Carli, M., Mariotti, S., Pinchera, A., Chretien, S., Romagnani, S. and Ricci, M. 1989. High potential to tumor necrosis factor α (TNF-α) production of thyroid infiltrating lymphocytes in Hasimoto's thyroiditis: A peculiar feature of destructive thyroid autoimmunity. Autoimmunity 4:267.
    • (1989) Autoimmunity , vol.4 , pp. 267
    • Del Prete, G.F.1    Tiri, A.2    De Carli, M.3    Mariotti, S.4    Pinchera, A.5    Chretien, S.6    Romagnani, S.7    Ricci, M.8
  • 43
    • 0026717674 scopus 로고
    • The pathophysiology of tumor necrosis factors
    • Vassalli, P. 1992. The pathophysiology of tumor necrosis factors. Annu. Rev. Immunol. 10:411.
    • (1992) Annu. Rev. Immunol. , vol.10 , pp. 411
    • Vassalli, P.1
  • 44
    • 0032948046 scopus 로고    scopus 로고
    • Macrophages are a significant source of type 1 cytokines during mycobacterial infection
    • Wang, J., Wakeham, J., Harkness, R. and Xing, Z. 1999. Macrophages are a significant source of type 1 cytokines during mycobacterial infection. J. Clin. Investigation 103:1023.
    • (1999) J. Clin. Investigation , vol.103 , pp. 1023
    • Wang, J.1    Wakeham, J.2    Harkness, R.3    Xing, Z.4
  • 45
    • 0030867026 scopus 로고    scopus 로고
    • Gamma interferon induces Fas-dependant apoptosis of peyer's patch T cells in mice following personal infection with Toxoplasma gondii
    • Liesenfeld, O., Kosek, J. and Suzuki, Y. 1997. Gamma interferon induces Fas-dependant apoptosis of peyer's patch T cells in mice following personal infection with Toxoplasma gondii. Infect. Immun. 65:468.
    • (1997) Infect. Immun. , vol.65 , pp. 468
    • Liesenfeld, O.1    Kosek, J.2    Suzuki, Y.3
  • 46
    • 0029834839 scopus 로고    scopus 로고
    • Local expression of transgene encoded TNF alpha in islets prevents autoimmune diabetes in nonobese diabetic (NOD) mice by preventing the development of auto-reactive islet-specific T cells
    • Grewal, I. S., Grewal, K. D., Wong, F. S., Picarella, D. E., Janeway, C. A. and Flavell, R. A. 1996. Local expression of transgene encoded TNF alpha in islets prevents autoimmune diabetes in nonobese diabetic (NOD) mice by preventing the development of auto-reactive islet-specific T cells. J. Exp. Med. 184:1963.
    • (1996) J. Exp. Med. , vol.184 , pp. 1963
    • Grewal, I.S.1    Grewal, K.D.2    Wong, F.S.3    Picarella, D.E.4    Janeway, C.A.5    Flavell, R.A.6
  • 47
    • 0031573621 scopus 로고    scopus 로고
    • TNF-α down-regulates type 1 cytokines and prolongs survival of syngeneic islet grafts in nonobese diabetic mice
    • Rabinovitch, A., Suarez-Pinzon, W. L., Sorensen, O., Rajotte, R. V. and Power, R. F. 1997. TNF-α down-regulates type 1 cytokines and prolongs survival of syngeneic islet grafts in nonobese diabetic mice. J. Immunol. 159:6298.
    • (1997) J. Immunol. , vol.159 , pp. 6298
    • Rabinovitch, A.1    Suarez-Pinzon, W.L.2    Sorensen, O.3    Rajotte, R.V.4    Power, R.F.5
  • 48
    • 0032918788 scopus 로고    scopus 로고
    • Mechanisms of mycobacterium avium-induced resistance against insulin-dependent diabetes mellitus (IDDM) in non-obese diabetic (NOD) mice: Role of Fas and Th1 cells
    • Martins, T. C. and Aguas, A. P. 1999. Mechanisms of mycobacterium avium-induced resistance against insulin-dependent diabetes mellitus (IDDM) in non-obese diabetic (NOD) mice: role of Fas and Th1 cells. Clin. Exp. Immunol. 115:248.
    • (1999) Clin. Exp. Immunol. , vol.115 , pp. 248
    • Martins, T.C.1    Aguas, A.P.2
  • 49
    • 0031033767 scopus 로고    scopus 로고
    • Prevention of autoimmune diabetes mellitus in NOD mice by transgenic expression of soluble tumor necrosis factor receptor p55
    • Hunger, R. E., Carnaud, C., Garcia, I., Vassalli, P. and Mueller, C. 1997. Prevention of autoimmune diabetes mellitus in NOD mice by transgenic expression of soluble tumor necrosis factor receptor p55. Eur. J. Immunol. 27:255.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 255
    • Hunger, R.E.1    Carnaud, C.2    Garcia, I.3    Vassalli, P.4    Mueller, C.5


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