Novel mechanisms of Na+ retention in obesity: Phosphorylation of NKCC2 and regulation of SPAK/OSR1 by AMPK

American Journal of Physiology - Renal Physiology

Volumn 307, Issue 1, 2014, Pages

  Davies, Matthew ^a   Fraser, Scott A ^a   Galic, Sandra ^b   Choy, Suet Wan ^a   Katerelos, Marina ^a   Gleich, Kurt ^a   Kemp, Bruce E ^b   Mount, Peter F ^a   Power, David A ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b ST VINCENT'S INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

AMP activated protein kinase; Oxidative stress responsive 1 kinase; STE 20 SPS1 related proline alaninerich protein kinase

Indexed keywords

BETA TUBULIN; EPITHELIAL SODIUM CHANNEL; FUROSEMIDE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; LEPTIN; OXIDATIVE STRESS RESPONSIVE 1 KINASE; PROTEIN KINASE; SODIUM POTASSIUM CHLORIDE COTRANSPORTER 2; UNCLASSIFIED DRUG;

ABDOMINAL FAT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BASOLATERAL MEMBRANE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; FIBROBLAST; IN VITRO STUDY; INSULIN BLOOD LEVEL; KIDNEY CORTEX; KIDNEY DISTAL TUBULE; KIDNEY MASS; KIDNEY TUBULE ABSORPTION; LIPID STORAGE; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SODIUM RETENTION; SYSTOLIC BLOOD PRESSURE; WEIGHT GAIN; WESTERN BLOTTING;

AMP-ACTIVATED PROTEIN KINASE; NA+-K+-2CL- COTRANSPORTER; OXIDATIVE STRESS RESPONSIVE 1 KINASE; STE-20/SPS1-RELATED PROLINE-ALANINE-RICH PROTEIN KINASE;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; EPITHELIAL SODIUM CHANNELS; KIDNEY; MICE; MICE, INBRED C57BL; OBESITY; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; SODIUM CHLORIDE, DIETARY; SOLUTE CARRIER FAMILY 12, MEMBER 1;

EID: 84903649086     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00524.2013     Document Type: Article

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