-
1
-
-
33746644724
-
WNK1 and OSR1 regulate the Na+, K+, 2Cl- Cotransporter in HeLa cells
-
Anselmo, A. N., Earnest, S., Chen, W., Juang, Y. C., Kim, S. C., Zhao, Y. and Cobb, M. H. (2006). WNK1 and OSR1 regulate the Na+, K+, 2Cl- cotransporter in HeLa cells. Proc. Natl. Acad. Sci. USA 103, 10883-10888.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 10883-10888
-
-
Anselmo, A.N.1
Earnest, S.2
Chen, W.3
Juang, Y.C.4
Kim, S.C.5
Zhao, Y.6
Cobb, M.H.7
-
2
-
-
36549040859
-
The selectivity of protein kinase inhibitors: A further update
-
Bain, J., Plater, L., Elliott, M., Shpiro, N., Hastie, C. J., McLauchlan, H., Klevernic, I., Arthur, J. S., Alessi, D. R. and Cohen, P. (2007). The selectivity of protein kinase inhibitors: a further update. Biochem. J. 408, 297-315.
-
(2007)
Biochem. J.
, vol.408
, pp. 297-315
-
-
Bain, J.1
Plater, L.2
Elliott, M.3
Shpiro, N.4
Hastie, C.J.5
McLauchlan, H.6
Klevernic, I.7
Arthur, J.S.8
Alessi, D.R.9
Cohen, P.10
-
3
-
-
33745076253
-
WNK4 kinase regulates surface expression of the human sodium chloride cotransporter in mammalian cells
-
Cai, H., Cebotaru, V., Wang, Y. H., Zhang, X. M., Cebotaru, L., Guggino, S. E. and Guggino, W. B. (2006). WNK4 kinase regulates surface expression of the human sodium chloride cotransporter in mammalian cells. Kidney Int. 69, 2162-2170.
-
(2006)
Kidney Int.
, vol.69
, pp. 2162-2170
-
-
Cai, H.1
Cebotaru, V.2
Wang, Y.H.3
Zhang, X.M.4
Cebotaru, L.5
Guggino, S.E.6
Guggino, W.B.7
-
4
-
-
77953203971
-
Localization and functional characterization of the human NKCC2 isoforms
-
Carota, I., Theilig, F., Oppermann, M., Kongsuphol, P., Rosenauer, A., Schreiber, R., Jensen, B. L., Walter, S., Kunzelmann, K. and Castrop, H. (2010) Localization and functional characterization of the human NKCC2 isoforms. Acta Physiol. (Oxf.) 199, 327-338.
-
(2010)
Acta Physiol. (Oxf.)
, vol.199
, pp. 327-338
-
-
Carota, I.1
Theilig, F.2
Oppermann, M.3
Kongsuphol, P.4
Rosenauer, A.5
Schreiber, R.6
Jensen, B.L.7
Walter, S.8
Kunzelmann, K.9
Castrop, H.10
-
5
-
-
57049184164
-
Isoforms of renal Na-K-2Cl cotransporter NKCC2: Expression and functional significance
-
Castrop, H. and Schnermann, J. (2008). Isoforms of renal Na-K-2Cl cotransporter NKCC2: expression and functional significance. Am. J. Physiol. Renal Physiol. 295, F859-F866.
-
(2008)
Am. J. Physiol. Renal Physiol.
, vol.295
-
-
Castrop, H.1
Schnermann, J.2
-
6
-
-
56549094967
-
Dietary salt regulates the phosphorylation of OSR1/SPAK kinases and the sodium chloride cotransporter through aldosterone
-
Chiga, M., Rai, T., Yang, S. S., Ohta, A., Takizawa, T., Sasaki, S. and Uchida, S. (2008). Dietary salt regulates the phosphorylation of OSR1/SPAK kinases and the sodium chloride cotransporter through aldosterone. Kidney Int. 74, 1403-1409.
-
(2008)
Kidney Int.
, vol.74
, pp. 1403-1409
-
-
Chiga, M.1
Rai, T.2
Yang, S.S.3
Ohta, A.4
Takizawa, T.5
Sasaki, S.6
Uchida, S.7
-
7
-
-
65949091159
-
Low salt concentrations activate AMP-activated protein kinase in mouse macula densa cells
-
Cook, N., Fraser, S. A., Katerelos, M., Katsis, F., Gleich, K., Mount, P. F., Steinberg, G. R., Levidiotis, V., Kemp, B. E. and Power, D. A. (2009). Low salt concentrations activate AMP-activated protein kinase in mouse macula densa cells. Am. J. Physiol. Renal Physiol. 296, F801-F809.
-
(2009)
Am. J. Physiol. Renal Physiol.
, vol.296
-
-
Cook, N.1
Fraser, S.A.2
Katerelos, M.3
Katsis, F.4
Gleich, K.5
Mount, P.F.6
Steinberg, G.R.7
Levidiotis, V.8
Kemp, B.E.9
Power, D.A.10
-
8
-
-
0037020145
-
A regulatory locus of phosphorylation in the N terminus of the Na-K-Cl cotransporter, NKCC1
-
Darman, R. B. and Forbush, B. (2002). A regulatory locus of phosphorylation in the N terminus of the Na-K-Cl cotransporter, NKCC1. J. Biol. Chem. 277, 37542-37550.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 37542-37550
-
-
Darman, R.B.1
Forbush, B.2
-
9
-
-
0042847432
-
Pask (proline-alanine-rich STE20-related kinase), a regulatory kinase of the Na-K-Cl cotransporter (NKCC1)
-
DOI 10.1074/jbc.M301899200
-
Dowd, B. F. and Forbush, B. (2003). PASK (proline-alanine-rich STE20-related kinase), a regulatory kinase of the Na-K-Cl cotransporter (NKCC1). J. Biol. Chem. 278, 27347-27353. (Pubitemid 36899915)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.30
, pp. 27347-27353
-
-
Dowd, B.F.X.1
Forbush, B.2
-
10
-
-
0037082158
-
High-level and high-throughput recombinant protein production by transient transfection of suspension-growing human 293-EBNA1 cells
-
Durocher, Y., Perret, S. and Kamen, A. (2002). High-level and high-throughput recombinant protein production by transient transfection of suspension-growing human 293-EBNA1 cells. Nucleic Acids Res. 30, E9.
-
(2002)
Nucleic Acids Res.
, vol.30
-
-
Durocher, Y.1
Perret, S.2
Kamen, A.3
-
11
-
-
39149129333
-
Cotransporters, WNKs and hypertension: An update
-
Flatman, P. W. (2008). Cotransporters, WNKs and hypertension: an update. Curr. Opin. Nephrol. Hypertens. 17, 186-192.
-
(2008)
Curr. Opin. Nephrol. Hypertens.
, vol.17
, pp. 186-192
-
-
Flatman, P.W.1
-
12
-
-
34347248366
-
Regulation of the renal-specific Na+-K+-2Cl- Co-transporter NKCC2 by AMP-activated protein kinase (AMPK)
-
Fraser, S. A., Gimenez, I., Cook, N., Jennings, I., Katerelos, M., Katsis, F., Levidiotis, V., Kemp, B. E. and Power, D. A. (2007). Regulation of the renal-specific Na+-K+-2Cl- co-transporter NKCC2 by AMP-activated protein kinase (AMPK). Biochem. J. 405, 85-93.
-
(2007)
Biochem. J.
, vol.405
, pp. 85-93
-
-
Fraser, S.A.1
Gimenez, I.2
Cook, N.3
Jennings, I.4
Katerelos, M.5
Katsis, F.6
Levidiotis, V.7
Kemp, B.E.8
Power, D.A.9
-
13
-
-
34250785553
-
A single binding motif is required for SPAK activation of the Na-K-2Cl cotransporter
-
DOI 10.1159/000104161
-
Gagnon, K. B., England, R. and Delpire, E. (2007). A single binding motif is required for SPAK activation of the Na-K-2Cl cotransporter. Cell. Physiol. Biochem. 20, 131-142. (Pubitemid 46956819)
-
(2007)
Cellular Physiology and Biochemistry
, vol.20
, Issue.1-4
, pp. 131-142
-
-
Gagnon, K.B.E.1
England, R.2
Delpire, E.3
-
14
-
-
15544384004
-
Molecular physiology and pathophysiology of electroneutral cation-chloride cotransporters
-
Gamba, G. (2005). Molecular physiology and pathophysiology of electroneutral cation-chloride cotransporters. Physiol. Rev. 85, 423-493.
-
(2005)
Physiol. Rev.
, vol.85
, pp. 423-493
-
-
Gamba, G.1
-
15
-
-
0038035205
-
Short-term stimulation of the renal Na-K-Cl cotransporter (NKCC2) by vasopressin involves phosphorylation and membrane translocation of the protein
-
DOI 10.1074/jbc.M303435200
-
Gimenez, I. and Forbush, B. (2003). Short-term stimulation of the renal Na-K-Cl cotransporter (NKCC2) by vasopressin involves phosphorylation and membrane translocation of the protein. J. Biol. Chem. 278, 26946-26951. (Pubitemid 36876847)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.29
, pp. 26946-26951
-
-
Gimenez, I.1
Forbush, B.2
-
16
-
-
27944505600
-
2 terminus of the renal Na-K-Cl cotransporter (NKCC2)
-
DOI 10.1152/ajprenal.00214.2005
-
Gimenez, I. and Forbush, B. (2005). Regulatory phosphorylation sites in the NH2 terminus of the renal Na-K-Cl cotransporter (NKCC2). Am. J. Physiol. Renal Physiol. 289, F1341-F1345. (Pubitemid 41681369)
-
(2005)
American Journal of Physiology - Renal Physiology
, vol.289
, Issue.6
-
-
Gimenez, I.1
Forbush, B.2
-
17
-
-
0037088671
-
Spatially distributed alternative splice variants of the renal Na-K-Cl cotransporter exhibit dramatically different affinities for the transported ions
-
DOI 10.1074/jbc.C200021200
-
Gimenez, I., Isenring, P. and Forbush, B. (2002). Spatially distributed alternative splice variants of the renal Na-K-Cl cotransporter exhibit dramatically different affinities for the transported ions. J. Biol. Chem. 277, 8767-8770. (Pubitemid 34952940)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.11
, pp. 8767-8770
-
-
Gimenez, I.1
Isenring, P.2
Forbush, B.3
-
18
-
-
23244460555
-
A new kindred with pseudohypoaldosteronism type II and a novel mutation (564D>H) in the acidic motif of the WNK4 gene
-
Golbang, A. P., Murthy, M., Hamad, A., Liu, C. H., Cope, G., Van't Hoff, W., Cuthbert, A. and O'Shaughnessy, K. M. (2005). A new kindred with pseudohypoaldosteronism type II and a novel mutation (564D>H) in the acidic motif of the WNK4 gene. Hypertension 46, 295-300.
-
(2005)
Hypertension
, vol.46
, pp. 295-300
-
-
Golbang, A.P.1
Murthy, M.2
Hamad, A.3
Liu, C.H.4
Cope, G.5
Van't Hoff, W.6
Cuthbert, A.7
O'Shaughnessy, K.M.8
-
19
-
-
72149129764
-
Functional expression of the Na-K-2Cl cotransporter NKCC2 in mammalian cells fails to confirm the dominantnegative effect of the AF splice variant
-
Hannemann, A., Christie, J. K. and Flatman, P. W. (2009). Functional expression of the Na-K-2Cl cotransporter NKCC2 in mammalian cells fails to confirm the dominantnegative effect of the AF splice variant. J. Biol. Chem. 284, 35348-35358.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 35348-35358
-
-
Hannemann, A.1
Christie, J.K.2
Flatman, P.W.3
-
20
-
-
22844441657
-
Properties of WNK1 and implications for other family members
-
Lenertz, L. Y., Lee, B. H., Min, X., Xu, B. E., Wedin, K., Earnest, S., Goldsmith, E. J. and Cobb, M. H. (2005). Properties of WNK1 and implications for other family members. J. Biol. Chem. 280, 26653-26658.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 26653-26658
-
-
Lenertz, L.Y.1
Lee, B.H.2
Min, X.3
Xu, B.E.4
Wedin, K.5
Earnest, S.6
Goldsmith, E.J.7
Cobb, M.H.8
-
21
-
-
18844431326
-
Phenotype and genotype analysis in Chinese patients with Gitelman's syndrome
-
Lin, S. H., Shiang, J. C., Huang, C. C., Yang, S. S., Hsu, Y. J. and Cheng, C. J. (2005). Phenotype and genotype analysis in Chinese patients with Gitelman's syndrome. J. Clin. Endocrinol. Metab. 90, 2500-2507.
-
(2005)
J. Clin. Endocrinol. Metab.
, vol.90
, pp. 2500-2507
-
-
Lin, S.H.1
Shiang, J.C.2
Huang, C.C.3
Yang, S.S.4
Hsu, Y.J.5
Cheng, C.J.6
-
22
-
-
3242664214
-
Four novel mutations in the thiazide-sensitive Na-Cl co-transporter gene in Japanese patients with Gitelman's syndrome
-
DOI 10.1093/ndt/gfh239
-
Maki, N., Komatsuda, A., Wakui, H., Ohtani, H., Kigawa, A., Aiba, N., Hamai, K., Motegi, M., Yamaguchi, A., Imai, H. et al. (2004). Four novel mutations in the thiazide-sensitive Na-Cl co-transporter gene in Japanese patients with Gitelman's syndrome. Nephrol. Dial. Transplant. 19, 1761-1766. (Pubitemid 38961384)
-
(2004)
Nephrology Dialysis Transplantation
, vol.19
, Issue.7
, pp. 1761-1766
-
-
Maki, N.1
Komatsuda, A.2
Wakui, H.3
Ohtani, H.4
Kigawa, A.5
Aiba, N.6
Hamai, K.7
Motegi, M.8
Yamaguchi, A.9
Imai, H.10
Sawada, K.-I.11
-
23
-
-
30044442784
-
WNK1 regulates phosphorylation of cation-chloride-coupled cotransporters via the STE20-related kinases, SPAK and OSR1
-
DOI 10.1074/jbc.M510042200
-
Moriguchi, T., Urushiyama, S., Hisamoto, N., Iemura, S., Uchida, S., Natsume, T., Matsumoto, K. and Shibuya, H. (2005). WNK1 regulates phosphorylation of cation-chloride-coupled cotransporters via the STE20-related kinases, SPAK and OSR1. J. Biol. Chem. 280, 42685-42693. (Pubitemid 43049227)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.52
, pp. 42685-42693
-
-
Moriguchi, T.1
Urushiyama, S.2
Hisamoto, N.3
Iemura, S.-I.4
Uchida, S.5
Natsume, T.6
Matsumoto, K.7
Shibuya, H.8
-
25
-
-
33749386424
-
- cotransporter is activated and phosphorylated at the amino-terminal domain upon intracellular chloride depletion
-
DOI 10.1074/jbc.M603773200
-
Pacheco-Alvarez, D., Cristobal, P. S., Meade, P., Moreno, E., Vazquez, N., Munoz, E., Diaz, A., Juarez, M. E., Gimenez, I. and Gamba, G. (2006). The Na+:Cl- cotransporter is activated and phosphorylated at the amino-terminal domain upon intracellular chloride depletion. J. Biol. Chem. 281, 28755-28763. (Pubitemid 44507018)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.39
, pp. 28755-28763
-
-
Pacheco-Alvarez, D.1
San, C.P.2
Meade, P.3
Moreno, E.4
Vazquez, N.5
Munoz, E.6
Diaz, A.7
Juarez, M.E.8
Gimenez, I.9
Gamba, G.10
-
26
-
-
33646584845
-
- transport
-
DOI 10.1152/ajprenal.00071.2005
-
Paredes, A., Plata, C., Rivera, M., Moreno, E., Vazquez, N., Munoz-Clares, R., Hebert, S. C. and Gamba, G. (2006). Activity of the renal Na+-K+-2Cl- cotransporter is reduced by mutagenesis of N-glycosylation sites: role for protein surface charge in Cltransport. Am. J. Physiol. Renal Physiol. 290, F1094-F1102. (Pubitemid 43724908)
-
(2006)
American Journal of Physiology - Renal Physiology
, vol.290
, Issue.5
-
-
Paredes, A.1
Plata, C.2
Rivera, M.3
Moreno, E.4
Vazquez, N.5
Munoz-Clares, R.6
Hebert, S.C.7
Gamba, G.8
-
27
-
-
0028296720
-
Alternatively spliced isoforms of the putative renal Na-K-Cl cotransporter are differentially distributed within the rabbit kidney
-
Payne, J. A. and Forbush, B., III (1994). Alternatively spliced isoforms of the putative renal Na-K-Cl cotransporter are differentially distributed within the rabbit kidney. Proc. Natl. Acad. Sci. USA 91, 4544-4548.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 4544-4548
-
-
Payne, J.A.1
Forbush III, B.2
-
28
-
-
0037184942
-
Cation chloride cotransporters interact with the stress-related kinases Ste20-related proline-alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1)
-
DOI 10.1074/jbc.M208108200
-
Piechotta, K., Lu, J. and Delpire, E. (2002). Cation chloride cotransporters interact with the stress-related kinases Ste20-related proline-alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1). J. Biol. Chem. 277, 50812-50819. (Pubitemid 36042246)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.52
, pp. 50812-50819
-
-
Piechotta, K.1
Lu, J.2
Delpire, E.3
-
29
-
-
0037192808
-
- cotransporter isoforms
-
DOI 10.1074/jbc.M110442200
-
Plata, C., Meade, P., Vazquez, N., Hebert, S. C. and Gamba, G. (2002). Functional properties of the apical Na+-K+-2Cl- cotransporter isoforms. J. Biol. Chem. 277, 11004-11012. (Pubitemid 34952857)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.13
, pp. 11004-11012
-
-
Plata, C.1
Meade, P.2
Vazquez, N.3
Hebert, S.C.4
Gamba, G.5
-
30
-
-
46149116565
-
Regulation of NKCC2 by a chloride-sensing mechanism involving the WNK3 and SPAK kinases
-
DOI 10.1073/pnas.0802966105
-
Ponce-Coria, J., San-Cristobal, P., Kahle, K. T., Vazquez, N., Pacheco-Alvarez, D., de Los Heros, P., Juarez, P., Munoz, E., Michel, G., Bobadilla, N. A. et al. (2008). Regulation of NKCC2 by a chloride-sensing mechanism involving the WNK3 and SPAK kinases. Proc. Natl. Acad. Sci. USA 105, 8458-8463. (Pubitemid 351904778)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.24
, pp. 8458-8463
-
-
Ponce-Coria, J.1
San-Cristobal, P.2
Kahle, K.T.3
Vazquez, N.4
Pacheco-Alvarez, D.5
De Los, H.P.6
Juarez, P.7
Munoz, E.8
Michel, G.9
Bobadilla, N.A.10
Gimenez, I.11
Lifton, R.P.12
Hebert, S.C.13
Gamba, G.14
-
31
-
-
77953459148
-
Role of the WNK-activated SPAK kinase in regulating blood pressure
-
Rafiqi, F. H., Zuber, A. M., Glover, M., Richardson, C., Fleming, S., Jovanovic, S., Jovanovic, A., O'Shaughnessy, K. M. and Alessi, D. R. (2010). Role of the WNK-activated SPAK kinase in regulating blood pressure. EMBO Mol. Med. 2, 63-75.
-
(2010)
EMBO Mol. Med.
, vol.2
, pp. 63-75
-
-
Rafiqi, F.H.1
Zuber, A.M.2
Glover, M.3
Richardson, C.4
Fleming, S.5
Jovanovic, S.6
Jovanovic, A.7
O'Shaughnessy, K.M.8
Alessi, D.R.9
-
32
-
-
56349151939
-
The regulation of salt transport and blood pressure by the WNK-SPAK/OSR1 signalling pathway
-
Richardson, C. and Alessi, D. R. (2008). The regulation of salt transport and blood pressure by the WNK-SPAK/OSR1 signalling pathway. J. Cell Sci. 121, 3293-3304.
-
(2008)
J. Cell Sci.
, vol.121
, pp. 3293-3304
-
-
Richardson, C.1
Alessi, D.R.2
-
33
-
-
42149175531
-
Activation of the thiazide-sensitive Na+-Cl- Cotransporter by the WNK-regulated kinases SPAK and OSR1
-
Richardson, C., Rafiqi, F. H., Karlsson, H. K., Moleleki, N., Vandewalle, A., Campbell, D. G., Morrice, N. A. and Alessi, D. R. (2008). Activation of the thiazide-sensitive Na+-Cl- cotransporter by the WNK-regulated kinases SPAK and OSR1. J. Cell Sci. 121, 675-684.
-
(2008)
J. Cell Sci.
, vol.121
, pp. 675-684
-
-
Richardson, C.1
Rafiqi, F.H.2
Karlsson, H.K.3
Moleleki, N.4
Vandewalle, A.5
Campbell, D.G.6
Morrice, N.A.7
Alessi, D.R.8
-
34
-
-
42549151627
-
Novel SLC12A3 mutations in Chinese patients with Gitelman's syndrome
-
Shao, L., Ren, H., Wang, W., Zhang, W., Feng, X., Li, X. and Chen, N. (2008). Novel SLC12A3 mutations in Chinese patients with Gitelman's syndrome. Nephron Physiol. 108, p29-36.
-
(2008)
Nephron Physiol.
, vol.108
, pp. 29-36
-
-
Shao, L.1
Ren, H.2
Wang, W.3
Zhang, W.4
Feng, X.5
Li, X.6
Chen, N.7
-
35
-
-
0030032699
-
Bartter's syndrome, hypokalaemic alkalosis with hypercalciuria, is caused by mutations in the Na-K-2Cl cotransporter NKCC2
-
Simon, D. B., Karet, F. E., Hamdan, J. M., DiPietro, A., Sanjad, S. A. and Lifton, R. P. (1996a). Bartter's syndrome, hypokalaemic alkalosis with hypercalciuria, is caused by mutations in the Na-K-2Cl cotransporter NKCC2. Nat. Genet. 13, 183-188.
-
(1996)
Nat. Genet.
, vol.13
, pp. 183-188
-
-
Simon, D.B.1
Karet, F.E.2
Hamdan, J.M.3
DiPietro, A.4
Sanjad, S.A.5
Lifton, R.P.6
-
36
-
-
9044235777
-
Gitelman's variant of Bartter's syndrome, inherited hypokalaemic alkalosis, is caused by mutations in the thiazide-sensitive Na-Cl cotransporter
-
DOI 10.1038/ng0196-24
-
Simon, D. B., Nelson-Williams, C., Bia, M. J., Ellison, D., Karet, F. E., Molina, A. M., Vaara, I., Iwata, F., Cushner, H. M., Koolen, M. et al. (1996b). Gitelman's variant of Bartter's syndrome, inherited hypokalaemic alkalosis, is caused by mutations in the thiazide-sensitive Na-Cl cotransporter. Nat. Genet. 12, 24-30. (Pubitemid 26011315)
-
(1996)
Nature Genetics
, vol.12
, Issue.1
, pp. 24-30
-
-
Simon, D.B.1
Nelson-Williams, C.2
Bia, M.J.3
Ellison, D.4
Karet, F.E.5
Molina, A.M.6
Vaara, I.7
Iwata, F.8
Cushner, H.M.9
Koolen, M.10
Gainza, F.J.11
Gitelman, H.J.12
Lifton, R.P.13
-
37
-
-
0037498542
-
Mutations in the human Na-K-2Cl cotransporter (NKCC2) identified in Bartter syndrome type I consistently result in nonfunctional transporters
-
DOI 10.1097/01.ASN.0000064948.39199.A0
-
Starremans, P. G., Kersten, F. F., Knoers, N. V., van den Heuvel, L. P. and Bindels, R. J. (2003). Mutations in the human Na-K-2Cl cotransporter (NKCC2) identified in Bartter syndrome type I consistently result in nonfunctional transporters. J. Am. Soc. Nephrol. 14, 1419-1426. (Pubitemid 36687042)
-
(2003)
Journal of the American Society of Nephrology
, vol.14
, Issue.6
, pp. 1419-1426
-
-
Starremans, P.G.J.F.1
Kersten, F.F.J.2
Knoers, N.V.A.M.3
Van Den, H.L.P.W.J.4
Bindels, R.J.M.5
-
38
-
-
77949654325
-
Effect of angiotensin II on the WNK-OSR1/SPAK-NCC phosphorylation cascade in cultured mpkDCT cells and in vivo mouse kidney
-
Talati, G., Ohta, A., Rai, T., Sohara, E., Naito, S., Vandewalle, A., Sasaki, S. and Uchida, S. (2010). Effect of angiotensin II on the WNK-OSR1/SPAK-NCC phosphorylation cascade in cultured mpkDCT cells and in vivo mouse kidney. Biochem. Biophys. Res. Commun. 393, 844-848.
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.393
, pp. 844-848
-
-
Talati, G.1
Ohta, A.2
Rai, T.3
Sohara, E.4
Naito, S.5
Vandewalle, A.6
Sasaki, S.7
Uchida, S.8
-
39
-
-
0035140930
-
Vasopressin-stimulated chloride transport in transimmortalized mouse cell lines derived from the distal convoluted tubule and cortical and inner medullary collecting ducts
-
Van Huyen, J. P., Bens, M., Teulon, J. and Vandewalle, A. (2001). Vasopressin-stimulated chloride transport in transimmortalized mouse cell lines derived from the distal convoluted tubule and cortical and inner medullary collecting ducts. Nephrol. Dial. Transplant. 16, 238-245. (Pubitemid 32123909)
-
(2001)
Nephrology Dialysis Transplantation
, vol.16
, Issue.2
, pp. 238-245
-
-
Duong, V.H.J.-P.1
Bens, M.2
Teulon, J.3
Vandewalle, A.4
-
40
-
-
26844532768
-
The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases
-
Vitari, A. C., Deak, M., Morrice, N. A. and Alessi, D. R. (2005). The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases. Biochem. J. 391, 17-24.
-
(2005)
Biochem. J.
, vol.391
, pp. 17-24
-
-
Vitari, A.C.1
Deak, M.2
Morrice, N.A.3
Alessi, D.R.4
-
41
-
-
33745530924
-
Functional interactions of the SPAK/OSR1 kinases with their upstream activator WNK1 and downstream substrate NKCC1
-
Vitari, A. C., Thastrup, J., Rafiqi, F. H., Deak, M., Morrice, N. A., Karlsson, H. K. and Alessi, D. R. (2006). Functional interactions of the SPAK/OSR1 kinases with their upstream activator WNK1 and downstream substrate NKCC1. Biochem. J. 397, 223-231.
-
(2006)
Biochem. J.
, vol.397
, pp. 223-231
-
-
Vitari, A.C.1
Thastrup, J.2
Rafiqi, F.H.3
Deak, M.4
Morrice, N.A.5
Karlsson, H.K.6
Alessi, D.R.7
-
42
-
-
17944373014
-
Human hypertension caused by mutations in WNK kinases
-
DOI 10.1126/science.1062844
-
Wilson, F. H., Disse-Nicodeme, S., Choate, K. A., Ishikawa, K., Nelson-Williams, C., Desitter, I., Gunel, M., Milford, D. V., Lipkin, G. W., Achard, J. M. et al. (2001). Human hypertension caused by mutations in WNK kinases. Science 293, 1107-1112. (Pubitemid 32758085)
-
(2001)
Science
, vol.293
, Issue.5532
, pp. 1107-1112
-
-
Wilson, F.H.1
Disse-Nicodeme, S.2
Choate, K.A.3
Ishikawa, K.4
Nelson-Williams, C.5
Desitter, I.6
Gunel, M.7
Milford, D.V.8
Lipkin, G.W.9
Achard, J.-M.10
Feely, M.P.11
Dussol, B.12
Berland, Y.13
Unwin, R.J.14
Mayan, H.15
Simon, D.B.16
Farfel, Z.17
Jeunemaitre, X.18
Lifton, R.P.19
-
43
-
-
0037457965
-
Molecular pathogenesis of inherited hypertension with hyperkalemia: The Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4
-
DOI 10.1073/pnas.242735399
-
Wilson, F. H., Kahle, K. T., Sabath, E., Lalioti, M. D., Rapson, A. K., Hoover, R. S., Hebert, S. C., Gamba, G. and Lifton, R. P. (2003). Molecular pathogenesis of inherited hypertension with hyperkalemia: the Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4. Proc. Natl. Acad. Sci. USA 100, 680-684. (Pubitemid 36126112)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.2
, pp. 680-684
-
-
Wilson, F.H.1
Kahle, K.T.2
Sabath, E.3
Lalioti, M.D.4
Rapson, A.K.5
Hoover, R.S.6
Hebert, S.C.7
Gamba, G.8
Lifton, R.P.9
-
44
-
-
34247617951
-
D561A/+ Knockin Mouse Model
-
DOI 10.1016/j.cmet.2007.03.009, PII S1550413107000721
-
Yang, S. S., Morimoto, T., Rai, T., Chiga, M., Sohara, E., Ohno, M., Uchida, K., Lin, S. H., Moriguchi, T., Shibuya, H. et al. (2007). Molecular pathogenesis of pseudohypoaldosteronism type II: generation and analysis of a Wnk4(D561A/+) knockin mouse model. Cell Metab. 5, 331-344. (Pubitemid 46679517)
-
(2007)
Cell Metabolism
, vol.5
, Issue.5
, pp. 331-344
-
-
Yang, S.-S.1
Morimoto, T.2
Rai, T.3
Chiga, M.4
Sohara, E.5
Ohno, M.6
Uchida, K.7
Lin, S.-H.8
Moriguchi, T.9
Shibuya, H.10
Kondo, Y.11
Sasaki, S.12
Uchida, S.13
-
45
-
-
0034535069
-
2 release and cyclooxygenase-2 expression in a mouse macula densa cell line
-
DOI 10.1074/jbc.M006218200
-
Yang, T., Park, J. M., Arend, L., Huang, Y., Topaloglu, R., Pasumarthy, A., Praetorius, H., Spring, K., Briggs, J. P. and Schnermann, J. (2000). Low chloride stimulation of prostaglandin E2 release and cyclooxygenase-2 expression in a mouse macula densa cell line. J. Biol. Chem. 275, 37922-37929. (Pubitemid 32004912)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.48
, pp. 37922-37929
-
-
Yang, T.1
Park, J.M.2
Arend, L.3
Huang, Y.4
Topaloglu, R.5
Pasumarthy, A.6
Praetorius, H.7
Spring, K.8
Briggs, J.P.9
Schnermann, J.10
-
46
-
-
33845970213
-
Regulation of activity and localization of the WNK1 protein kinase by hyperosmotic stress
-
DOI 10.1083/jcb.200605093
-
Zagorska, A., Pozo-Guisado, E., Boudeau, J., Vitari, A. C., Rafiqi, F. H., Thastrup, J., Deak, M., Campbell, D. G., Morrice, N. A., Prescott, A. R. et al. (2007). Regulation of activity and localization of the WNK1 protein kinase by hyperosmotic stress. J. Cell Biol. 176, 89-100. (Pubitemid 46041683)
-
(2007)
Journal of Cell Biology
, vol.176
, Issue.1
, pp. 89-100
-
-
Zagorska, A.1
Pozo-Guisado, E.2
Boudeau, J.3
Vitari, A.C.4
Rafiqi, F.H.5
Thastrup, J.6
Deak, M.7
Campbell, D.G.8
Morrice, N.A.9
Prescott, A.R.10
Alessi, D.R.11
-
47
-
-
0034773404
-
Role of AMP-activated protein kinase in mechanism of metformin action
-
DOI 10.1172/JCI200113505
-
Zhou, G., Myers, R., Li, Y., Chen, Y., Shen, X., Fenyk-Melody, J., Wu, M., Ventre, J., Doebber, T., Fujii, N. et al. (2001). Role of AMP-activated protein kinase in mechanism of metformin action. J. Clin. Invest. 108, 1167-1174. (Pubitemid 32995375)
-
(2001)
Journal of Clinical Investigation
, vol.108
, Issue.8
, pp. 1167-1174
-
-
Zhou, G.1
Myers, R.2
Li, Y.3
Chen, Y.4
Shen, X.5
Fenyk-Melody, J.6
Wu, M.7
Ventre, J.8
Doebber, T.9
Fujii, N.10
Musi, N.11
Hirshman, M.F.12
Goodyear, L.J.13
Moller, D.E.14
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