Attenuation of the cardiovascular and metabolic complications of obesity in CD14 knockout mice

Life Sciences

Volumn 83, Issue 13-14, 2008, Pages 502-510

  Roncon Albuquerque Jr , Roberto ^a   Moreira Rodrigues, Mónica ^a   Faria, Bernardo ^a   Ferreira, Andrea P ^b   Cerqueira, Cátia ^a   Lourenço, André P ^a   Pestana, Manuel ^a   von Hafe, Pedro ^a   Leite Moreira, Adelino F ^a  

^a Institute of Pharmacology and Therapeutics   (Portugal)

^b UNIVERSIDADE CATÓLICA PORTUGUESA   (Portugal)

Author keywords

CD14; CD14 knockout mice; Metabolic syndrome; Obesity; Toll like receptors

Indexed keywords

CD14 ANTIGEN; LIPOPOLYSACCHARIDE; MESSENGER RNA; NORADRENALIN; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA ANTIBODY;

ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE; BODY COMPOSITION; CARBOHYDRATE DIET; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; DISEASE ASSOCIATION; FATTY LIVER; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE; HYPERGLYCEMIA; HYPERTENSION; KNOCKOUT MOUSE; KUPFFER CELL; LIPID DIET; MALE; METABOLIC DISORDER; MOUSE; NONHUMAN; OBESITY; PROTEIN EXPRESSION; SYMPATHETIC TONE;

ADIPOSE TISSUE; ANIMALS; ANTIGENS, CD14; BLOOD PRESSURE; DIETARY FATS; FATTY LIVER; GENE EXPRESSION; GENE SILENCING; GLUCOSE TOLERANCE TEST; LIVER; MACROPHAGES; METABOLIC SYNDROME X; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NOREPINEPHRINE; OBESITY; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4;

MUS;

EID: 52049124227     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2008.07.021     Document Type: Article

References (38)

1. Ahima R.S., and Osei S.Y. Adipokines in obesity. Frontiers of Hormone Research 36 (2008) 182-197
2. Akira S. Toll-like receptor signaling. The Journal of Biological Chemistry 278 40 (2003) 38105-38108
3. Andonegui G., Goyert S.M., and Kubes P. Lipopolysaccharide-induced leukocyte-endothelial cell interactions: a role for CD14 versus toll-like receptor 4 within microvessels. Journal of Immunology 169 4 (2002) 2111-2119
4. Aneja A., El-Atat F., McFarlane S.I., and Sowers J.R. Hypertension and obesity. Recent Progress in Hormone Research 59 (2004) 169-205
5. Batra A., Pietsch J., Fedke I., Glauben R., Okur B., Stroh T., Zeitz M., and Siegmund B. Leptin-dependent toll-like receptor expression and responsiveness in preadipocytes and adipocytes. The American Journal of Pathology 170 6 (2007) 1931-1941
6. Brun P., Castagliuolo I., Di Leo V., Buda A., Pinzani M., Palu G., and Martines D. Increased intestinal permeability in obese mice: new evidence in the pathogenesis of nonalcoholic steatohepatitis. American Journal of Physiology: Gastrointestinal and Liver Physiology 292 2 (2007) G518-G525
7. Cani P.D., Amar J., Iglesias M.A., Poggi M., Knauf C., Bastelica D., Neyrinck A.M., Fava F., Tuohy K.M., Chabo C., Waget A., Delmee E., Cousin B., Sulpice T., Chamontin B., Ferrieres J., Tanti J.F., Gibson G.R., Casteilla L., Delzenne N.M., Alessi M.C., and Burcelin R. Metabolic endotoxemia initiates obesity and insulin resistance. Diabetes 56 7 (2007) 1761-1772
8. Di Gregorio G.B., Yao-Borengasser A., Rasouli N., Varma V., Lu T., Miles L.M., Ranganathan G., Peterson C.A., McGehee R.E., and Kern P.A. Expression of CD68 and macrophage chemoattractant protein-1 genes in human adipose and muscle tissues: association with cytokine expression, insulin resistance, and reduction by pioglitazone. Diabetes 54 8 (2005) 2305-2313
9. Folch J., Lees M., and Sloane Stanley G.H. A simple method for the isolation and purification of total lipides from animal tissues. The Journal of Biological Chemistry 226 1 (1957) 497-509
10. Johnson G.B., Riggs B.L., and Platt J.L. A genetic basis for the "Adonis" phenotype of low adiposity and strong bones. FASEB Journal 18 11 (2004) 1282-1284
11. Kanda H., Tateya S., Tamori Y., Kotani K., Hiasa K., Kitazawa R., Kitazawa S., Miyachi H., Maeda S., Egashira K., and Kasuga M. MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity. The Journal of Clinical Investigation 116 6 (2006) 1494-1505
12. Kirschning C.J., Wesche H., Merrill Ayres T., and Rothe M. Human toll-like receptor 2 confers responsiveness to bacterial lipopolysaccharide. The Journal of Experimental Medicine 188 11 (1998) 2091-2097
13. Kolios G., Valatas V., and Kouroumalis E. Role of Kupffer cells in the pathogenesis of liver disease. World Journal of Gastroenterology 12 46 (2006) 7413-7420
14. Lee J.Y., and Hwang D.H. The modulation of inflammatory gene expression by lipids: mediation through Toll-like receptors. Molecules and Cells 21 2 (2006) 174-185
15. Lee J.Y., Ye J., Gao Z., Youn H.S., Lee W.H., Zhao L., Sizemore N., and Hwang D.H. Reciprocal modulation of Toll-like receptor-4 signaling pathways involving MyD88 and phosphatidylinositol 3-kinase/AKT by saturated and polyunsaturated fatty acids. The Journal of Biological Chemistry 278 39 (2003) 37041-37051
16. Lembo G., Napoli R., Capaldo B., Rendina V., Iaccarino G., Volpe M., Trimarco B., and Sacca L. Abnormal sympathetic overactivity evoked by insulin in the skeletal muscle of patients with essential hypertension. The Journal of Clinical Investigation 90 1 (1992) 24-29
17. Lin Y., Lee H., Berg A.H., Lisanti M.P., Shapiro L., and Scherer P.E. The lipopolysaccharide-activated toll-like receptor (TLR)-4 induces synthesis of the closely related receptor TLR-2 in adipocytes. The Journal of Biological Chemistry 275 32 (2000) 24255-24263
18. Means T.K., Lien E., Yoshimura A., Wang S., Golenbock D.T., and Fenton M.J. The CD14 ligands lipoarabinomannan and lipopolysaccharide differ in their requirement for Toll-like receptors. Journal of Immunology 163 12 (1999) 6748-6755
19. Mills E., Kuhn C.M., Feinglos M.N., and Surwit R. Hypertension in CB57BL/6J mouse model of non-insulin-dependent diabetes mellitus. American Journal of Physiology 264 1 Pt 2 (1993) R73-R78
20. Ota A., Kaneko Y.S., Mori K., Nakashima A., Nagatsu I., and Nagatsu T. Effect of peripherally administered lipopolysaccharide (LPS) on GTP cyclohydrolase I, tetrahydrobiopterin and norepinephrine in the locus coeruleus in mice. Stress 10 2 (2007) 131-136
21. Pestana M., and Soares-da-Silva P. Effect of type A and B monoamine oxidase selective inhibition by Ro 41-1049 and Ro 19-6327 on dopamine outflow in rat kidney slices. British Journal of Pharmacology 113 4 (1994) 1269-1274
22. Pugin J., Heumann I.D., Tomasz A., Kravchenko V.V., Akamatsu Y., Nishijima M., Glauser M.P., Tobias P.S., and Ulevitch R.J. CD14 is a pattern recognition receptor. Immunity 1 6 (1994) 509-516
23. Rogers P., and Webb G.P. Estimation of body fat in normal and obese mice. British Journal of Nutrition 43 1 (1980) 83-86
24. Rossmeisl M., Rim J.S., Koza R.A., and Kozak L.P. Variation in type 2 diabetes-related traits in mouse strains susceptible to diet-induced obesity. Diabetes 52 8 (2003) 1958-1966
25. Semenkovich C.F. Insulin resistance and atherosclerosis. The Journal of Clinical Investigation 116 7 (2006) 1813-1822
26. Senn J.J. Toll-like receptor-2 is essential for the development of palmitate-induced insulin resistance in myotubes. The Journal of Biological Chemistry 281 37 (2006) 26865-26875
27. Shi H., Kokoeva M.V., Inouye K., Tzameli I., Yin H., and Flier J.S. TLR4 links innate immunity and fatty acid-induced insulin resistance. The Journal of Clinical Investigation 116 11 (2006) 3015-3025
28. Song M.J., Kim K.H., Yoon J.M., and Kim J.B. Activation of Toll-like receptor 4 is associated with insulin resistance in adipocytes. Biochemical and Biophysical Research Communications 346 3 (2006) 739-745
29. Surwit R.S., Kuhn C.M., Cochrane C., McCubbin J.A., and Feinglos M.N. Diet-induced type II diabetes in C57BL/6J mice. Diabetes 37 9 (1988) 1163-1167
30. Szabo G., Velayudham A., Romics Jr. L., and Mandrekar P. Modulation of non-alcoholic steatohepatitis by pattern recognition receptors in mice: the role of toll-like receptors 2 and 4. Alcoholism, Clinical and Experimental Research 29 11 Suppl (2005) 140S-145S
31. Tentolouris N., Liatis S., and Katsilambros N. Sympathetic system activity in obesity and metabolic syndrome. Annals of the New York Academy of Sciences 1083 (2006) 129-152
32. Tomita K., Tamiya G., Ando S., Ohsumi K., Chiyo T., Mizutani A., Kitamura N., Toda K., Kaneko T., Horie Y., Han J.Y., Kato S., Shimoda M., Oike Y., Tomizawa M., Makino S., Ohkura T., Saito H., Kumagai N., Nagata H., Ishii H., and Hibi T. Tumour necrosis factor alpha signalling through activation of Kupffer cells plays an essential role in liver fibrosis of non-alcoholic steatohepatitis in mice. Gut 55 3 (2006) 415-424
33. Viriyakosol S., Matthias M.A., Swancutt M.A., Kirkland T.N., and Vinetz J.M. Toll-like receptor 4 protects against lethal Leptospira interrogans serovar icterohaemorrhagiae infection and contributes to in vivo control of leptospiral burden. Infection and Immunity 74 2 (2006) 887-895
34. Weisberg S.P., McCann D., Desai M., Rosenbaum M., Leibel R.L., and Ferrante Jr. A.W. Obesity is associated with macrophage accumulation in adipose tissue. The Journal of Clinical Investigation 112 12 (2003) 1796-1808
35. Weisberg S.P., Hunter D., Huber R., Lemieux J., Slaymaker S., Vaddi K., Charo I., Leibel R.L., and Ferrante Jr. A.W. CCR2 modulates inflammatory and metabolic effects of high-fat feeding. The Journal of Clinical Investigation 116 1 (2006) 115-124
36. Wright S.D., Ramos R.A., Tobias P.S., Ulevitch R.J., and Mathison J.C. CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. Science 249 4975 (1990) 1431-1433
37. Yamaguchi N., Argueta J.G., Masuhiro Y., Kagishita M., Nonaka K., Saito T., Hanazawa S., and Yamashita Y. Adiponectin inhibits Toll-like receptor family-induced signaling. FEBS Letters 579 30 (2005) 6821-6826
38. Yang R.B., Mark M.R., Gray A., Huang A., Xie M.H., Zhang M., Goddard A., Wood W.I., Gurney A.L., and Godowski P.J. Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling. Nature 6699 (1998) 284-288