AMPK couples plasma renin to cellular metabolism by phosphorylation of ACC1

American Journal of Physiology - Renal Physiology

Volumn 305, Issue 5, 2013, Pages

  Fraser, Scott A ^a   Choy, Suet Wan ^a   Pastor Soler, Núria M ^b   Li, Hui ^b   Davies, Matthew R P ^a   Cook, Natasha ^a   Katerelos, Marina ^a   Mount, Peter F ^a   Gleich, Kurt ^a   Mcrae, Jennifer L ^c   Dwyer, Karen M ^c   van Denderen, Bryce J W ^d   Hallows, Kenneth R ^b   Kemp, Bruce E ^d   Power, David A ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c ST VINCENT S HOSPITAL   (Australia)

^d ST VINCENT'S INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

Acetyl CoA carboxylase 1; AMP activated protein kinase; Rennin

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; AMP ACTIVATED PROTEIN KINASE BETA1; CALCIUM ION; CHLORINE; CREATININE; CYCLOOXYGENASE 2; EPITHELIAL SODIUM CHANNEL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MAGNESIUM ION; MESSENGER RNA; POTASSIUM ION; PREPRORENIN; RENIN; SODIUM CHLORIDE; SODIUM ION; SODIUM POTASSIUM CHLORIDE COTRANSPORTER; UNCLASSIFIED DRUG; UREA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCIUM URINE LEVEL; CELL METABOLISM; CHLORIDE BLOOD LEVEL; CHLORIDE URINE LEVEL; CONTROLLED STUDY; ENZYME ACTIVITY; FATTY ACID METABOLISM; GENE DELETION; GENE EXPRESSION REGULATION; GENE TARGETING; HENLE LOOP; KIDNEY CORTEX; MACULA DENSA; MAGNESIUM URINE LEVEL; MOUSE; NONHUMAN; PLASMA RENIN ACTIVITY; POTASSIUM BLOOD LEVEL; POTASSIUM URINE LEVEL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RENIN RELEASE; SALT INTAKE; SODIUM BLOOD LEVEL; SODIUM URINE LEVEL;

EID: 84883315869     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00407.2012     Document Type: Article

References (62)

1. Allen TJ, Cooper ME, Gilbert RE, Winikoff J, Skinni SL, Jerums G. Serum total renin is increased before microalbuminuria in diabetes. Kidney Int 50: 902-907, 1996.
2. + channels through Nedd4-2 and causes an epithelial phenotype when mutated. Pflügers Arch 458: 713-721, 2009.
3. +-ATPase and mediates the adenosine monophosphate-stimulated protein kinase-dependent regulation of sodium pump surface expression. Mol Biol Cell 21: 4400-4408, 2010.
4. + channel through functional regulation of the ubiquitin ligase Nedd4-2. J Biol Chem 281: 26159-26169, 2006.
5. Brenner BM, Rector FC. Brenner & Rector's the Kidney. Philadelphia, PA: Saunders, 2008.
6. Brown D, Lydon J, McLaughlin M, Stuart-Tilley A, Tyszkowski R, Alper S. Antigen retrieval in cryostat tissue sections and cultured cells by treatment with sodium dodecyl sulfate (SDS). Histochem Cell Biol 105: 261-267, 1996.
7. Brownsey RW, Boone AN, Elliott JE, Kulpa JE, Lee WM. Regulation of acetyl-CoA carboxylase. Biochem Soc Trans 34: 223-227, 2006.
8. Butterworth MB. Regulation of the epithelial sodium channel (ENaC) by membrane trafficking. Biochim Biophys Acta 1802: 1166-1177, 2010.
9. Carattino MD, Edinger RS, Grieser HJ, Wise R, Neumann D, Schlattner U, Johnson JP, Kleyman TR, Hallows KR. Epithelial sodium channel inhibition by AMP-activated protein kinase in oocytes and polarized renal epithelial cells. J Biol Chem 280: 17608-17616, 2005.
10. Decleves AE, Mathew AV, Cunard R, Sharma K. AMPK mediates the initiation of kidney disease induced by a high-fat diet. J Am Soc Nephrol 22: 1846-1855, 2011.
11. Deji N, Kume S, Araki S, Isshiki K, Araki H, Chin-Kanasaki M, Tanaka Y, Nishiyama A, Koya D, Haneda M, Kashiwagi A, Maegawa H, Uzu T. Role of angiotensin II-mediated AMPK inactivation on obesityrelated salt-sensitive hypertension. Biochem Biophys Res Commun 418: 559-564, 2012.
12. Dickens F, Simer F. The metabolism of normal and tumour tissue: the respiratory quotient, and the relationship of respiration to glycolysis. Biochem J 24: 1301-1326, 1930.
13. Dzamko N, van Denderen BJ, Hevener AL, Jorgensen SB, Honeyman J, Galic S, Chen ZP, Watt MJ, Campbell DJ, Steinberg GR, Kemp BE. AMPK β1 deletion reduces appetite, preventing obesity and hepatic insulin resistance. J Biol Chem 285: 115-122, 2010.
14. Engeli S, Bohnke J, Gorzelniak K, Janke J, Schling P, Bader M, Luft FC, Sharma AM. Weight loss and the renin-angiotensin-aldosterone system. Hypertension 45: 356-362, 2005.
15. Flemmer AW, Gimenez I, Dowd BF, Darman RB, Forbush B. Activation of the Na-K-Cl cotransporter NKCC1 detected with a phosphospecific antibody. J Biol Chem 277: 37551-37558, 2002.
16. - co-transporter NKCC2 by AMP-activated protein kinase (AMPK). Biochem J 405: 85-93, 2007.
17. Frindt G, Palmer LG. Surface expression of sodium channels and transporters in rat kidney: effects of dietary sodium. Am J Physiol Renal Physiol 297: F1249-F1255, 2009.
18. Galic S, Fullerton MD, Schertzer JD, Sikkema S, Marcinko K, Walkley CR, Izon D, Honeyman J, Chen ZP, van Denderen BJ, Kemp BE, Steinberg GR. Hematopoietic AMPK β1 reduces mouse adipose tissue macrophage inflammation and insulin resistance in obesity. J Clin Invest 121: 4903-4915, 2011.
19. Gao G, Fernandez CS, Stapleton D, Auster AS, Widmer J, Dyck JR, Kemp BE, Witters LA. Non-catalytic β - and γ-subunit isoforms of the 5=-AMP-activated protein kinase. J Biol Chem 271: 8675-8681, 1996.
20. Gimenez I, Forbush B. Regulatory phosphorylation sites in the NH2 terminus of the renal Na-K-Cl cotransporter (NKCC2). Am J Physiol Renal Physiol 289: F1341-F1345, 2005.
21. Gimenez I, Forbush B. Short-term stimulation of the renal Na-K-Cl cotransporter (NKCC2) by vasopressin involves phosphorylation and membrane translocation of the protein. J Biol Chem 278: 26946-26951, 2003.
22. +-ATPase apical accumulation in kidney intercalated cells is regulated by PKA and AMP-activated protein kinase. Am J Physiol Renal Physiol 298: F1162-F1169, 2010.
23. Hardie DG. AMP-activated protein kinase: a cellular energy sensor with a key role in metabolic disorders and in cancer. Biochem Soc Trans 39: 1-13, 2011.
24. Harris RC, Zhang MZ, Cheng HF. Cyclooxygenase-2 and the renal renin-angiotensin system. Acta Physiol Scand 181: 543-547, 2004.
25. Hawley SA, Pan DA, Mustard KJ, Ross L, Bain J, Edelman AM, Frenguelli BG, Hardie DG. Calmodulin-dependent protein kinase kinase-β is an alternative upstream kinase for AMP-activated protein kinase. Cell Metab 2: 9-19, 2005.
26. 2+/calmodulin-dependent protein kinase kinases are AMP-activated protein kinase kinases. J Biol Chem 280: 29060-29066, 2005.
27. Iverson AJ, Bianchi A, Nordlund AC, Witters LA. Immunological analysis of acetyl-CoA carboxylase mass, tissue distribution and subunit composition. Biochem J 269: 365-371, 1990.
28. Jordan J, Engeli S, Boye SW, Le Breton S, Keefe DL. Direct renin inhibition with aliskiren in obese patients with arterial hypertension. Hypertension 49: 1047-1055, 2007.
29. Kahn BB, Alquier T, Carling D, Hardie DG. AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism. Cell Metab 1: 15-25, 2005.
30. Kiil F, Aukland K, Refsum HE. Renal sodium transport and oxygen consumption. Am J Physiol 201: 511-516, 1961.
31. Kim HS, Kim MJ, Kim EJ, Yang Y, Lee MS, Lim JS. Berberineinduced AMPK activation inhibits the metastatic potential of melanoma cells via reduction of ERK activity and COX-2 protein expression. Biochem Pharmacol 83: 385-394, 2012.
32. Kim SM, Mizel D, Huang YG, Briggs JP, Schnermann J. Adenosine as a mediator of macula densa-dependent inhibition of renin secretion. Am J Physiol Renal Physiol 290: F1016-F1023, 2006.
33. Lee JB, Peterhm. Effect of oxygen tension on glucose metabolism in rabbit kidney cortex and medulla. Am J Physiol 217: 1464-1471, 1969.
34. Lee MJ, Feliers D, Mariappan MM, Sataranatarajan K, Mahimainathan L, Musi N, Foretz M, Viollet B, Weinberg JM, Choudhury GG, Kasinath BS. A role for AMP-activated protein kinase in diabetesinduced renal hypertrophy. Am J Physiol Renal Physiol 292: F617-F627, 2007.
35. Lifton RP, Gharavi AG, Geller DS. Molecular mechanisms of human hypertension. Cell 104: 545-556, 2001.
36. +-ATPase activity in the cortical collecting duct (CCD). Am J Physiol Renal Physiol 302: F205-F215, 2012.
37. + transport in H441 lung epithelial cells. J Physiol 586: 4541-4557, 2008.
38. Masilamani S, Wang X, Kim GH, Brooks H, Nielsen J, Nielsen S, Nakamura K, Stokes JB, Knepper MA. Time course of renal Na-KATPase, NHE3, NKCC2, NCC, and ENaC abundance changes with dietary NaCl restriction. Am J Physiol Renal Physiol 283: F648-F657, 2002.
39. Matinlauri IH, Ronnemaa T, Koskinen PJ, Aalto MA, Vukari JS, Irjala KM. Elevated serum total renin is insensitive in detecting incipient diabetic nephropathy. Diabetes Care 18: 1357-1361, 1995.
40. Mendelsohn FA, Johnston CI. A radiochemical renin assay. Biochem J 121: 241-244, 1971.
41. Mount PF, Gleich K, Tam S, Fraser SA, Choy SW, Dwyer KM, Lu B, Denderen BV, Fingerle-Rowson G, Bucala R, Kemp BE, Power DA. The outcome of renal ischemia-reperfusion injury is unchanged in AMPK-β1 deficient mice. PLos One 7: e29887, 2012.
42. Mount PF, Hill RE, Fraser SA, Levidiotis V, Katsis F, Kemp BE, Power DA. Acute renal ischemia rapidly activates the energy sensor AMPK but does not increase phosphorylation of eNOS-Ser1177. Am J Physiol Renal Physiol 289: F1103-F1115, 2005.
43. Mount PF, Lane N, Venkatesan S, Steinberg GR, Fraser SA, Kemp BE, Power DA. Bradykinin stimulates endothelial cell fatty acid oxidation by CaMKK-dependent activation of AMPK. Atherosclerosis 200: 28-36, 2008.
44. Oakhill JS, Steel R, Chen ZP, Scott JW, Ling N, Tam S, Kemp BE. AMPK is a direct adenylate charge-regulated protein kinase. Science 332: 1433-1435, 2011.
45. Oppermann M, Mizel D, Huang G, Li C, Deng C, Theilig F, Bachmann S, Briggs J, Schnermann J, Castrop H. Macula densa control of renin secretion and preglomerular resistance in mice with selective deletion of the B isoform of the Na,K,2Cl co-transporter. J Am Soc Nephrol 17: 2143-2152, 2006.
46. Peti-Peterdi J, Harris RC. Macula densa sensing and signaling mechanisms of renin release. J Am Soc Nephrol 21: 1093-1096, 2010.
47. Pfaffl MW. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 29: e45, 2001.
48. Ponce-Coria J, San-Cristobal P, Kahle KT, Vazquez N, Pacheco- Alvarez D, de Los Heros P, Juarez P, Munoz E, Michel G, Bobadilla NA, Gimenez I, Lifton RP, Hebert SC, Gamba G. Regulation of NKCC2 by a chloride-sensing mechanism involving the WNK3 and SPAK kinases. Proc Natl Acad Sci USA 105: 8458-8463, 2008.
49. - cotransporter by the WNK-regulated kinases SPAK and OSR1. J Cell Sci 121: 675-684, 2008.
50. Saha AK, Ruderman NB. Malonyl-CoA and AMP-activated protein kinase: an expanding partnership. Mol Cell Biochem 253: 65-70, 2003.
51. Schnermann J, Briggs JP. Synthesis and secretion of renin in mice with induced genetic mutations. Kidney Int 81: 529-538, 2012.
52. Schnermann J, Briggs JP. Tubuloglomerular feedback: mechanistic insights from gene-manipulated mice. Kidney Int 74: 418-426, 2008.
53. Soltoff SP. ATP and the regulation of renal cell function. Annu Rev Physiol 48: 9-31, 1986.
54. Stapleton D, Mitchelhill KI, Gao G, Widmer J, Michell BJ, Teh T, House CM, Fernandez CS, Cox T, Witters LA, Kemp BE. Mammalian AMP-activated protein kinase subfamily. J Biol Chem 271: 611-614, 1996.
55. Steinberg GR, Kemp BE. AMPK in Health and Disease. Physiol Rev 89: 1025-1078, 2009.
56. Thatcher RL, Whitworth JA, Casley DG, Johnston CI, Skinner SL. A two-site monoclonal immunoradiometric assay for total renin protein: comparison with an established enzyme kinetic assay. Clin Exp Pharmacol Physiol 15: 285-288, 1988.
57. Tuck ML, Sowers J, Dornfeld L, Kledzik G, Maxwell M. The effect of weight reduction on blood pressure, plasma renin activity, and plasma aldosterone levels in obese patients. N Engl J Med 304: 930-933, 1981.
58. Viollet B, Andreelli F. AMP-activated protein kinase and metabolic control. Handb Exp Pharmacol: 303-330, 2011.
59. Whittam R. Active cation transport as a pace-maker of respiration. Nature 191: 603-604, 1961.
60. 2+/calmodulin-dependent protein kinase kinase-_ acts upstream of AMP-activated protein kinase in mammalian cells. Cell Metab 2: 21-33, 2005.
61. Woods A, Johnstone SR, Dickerson K, Leiper FC, Fryer LG, Neumann D, Schlattner U, Wallimann T, Carlson M, Carling D. LKB1 is the upstream kinase in the AMP-activated protein kinase cascade. Curr Biol 13: 2004-2008, 2003.
62. Yi CO, Jeon BT, Shin HJ, Jeong EA, Chang KC, Lee JE, Lee DH, Kim HJ, Kang SS, Cho GJ, Choi WS, Roh GS. Resveratrol activates AMPK and suppresses LPS-induced NF-κB-dependent COX-2 activation in RAW 264.7 macrophage cells. Anat Cell Biol 44: 194-203, 2011.