메뉴 건너뛰기




Volumn 13, Issue 1, 2012, Pages 17-26

Mechanisms linking obesity to hypertension

Author keywords

Hypertension; Metabolic syndrome; Obesity; Obesity related hypertension

Indexed keywords

ADIPONECTIN; ALDOSTERONE; ALDOSTERONE ANTAGONIST; ANTIHYPERTENSIVE AGENT; COLONY STIMULATING FACTOR 1; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENDOTHELIAL NITRIC OXIDE SYNTHASE; FATTY ACID; INSULIN; INTERLEUKIN 6; LEPTIN; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; RESISTIN; THIAZOLIDINE DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA;

EID: 83855164132     PISSN: 14677881     EISSN: 1467789X     Source Type: Journal    
DOI: 10.1111/j.1467-789X.2011.00914.x     Document Type: Review
Times cited : (168)

References (113)
  • 1
    • 33646006404 scopus 로고    scopus 로고
    • Diagnosis and management of hypertension in obesity
    • Narkiewicz K. Diagnosis and management of hypertension in obesity. Obes Rev 2006; 7: 155-162.
    • (2006) Obes Rev , vol.7 , pp. 155-162
    • Narkiewicz, K.1
  • 2
    • 77958088160 scopus 로고    scopus 로고
    • Obesity-related hypertension: epidemiology, pathophysiology, and clinical management
    • Kotchen TA. Obesity-related hypertension: epidemiology, pathophysiology, and clinical management. Am J Hypertens 2010; 23: 1170-1178.
    • (2010) Am J Hypertens , vol.23 , pp. 1170-1178
    • Kotchen, T.A.1
  • 3
    • 34547615709 scopus 로고    scopus 로고
    • 2007 Guidelines for the management of arterial hypertension: the task force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC)
    • Mancia G, De Backer G, Dominiczak A, Cifkova R, Fagard R, Germano G etal. 2007 Guidelines for the management of arterial hypertension: the task force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). Eur Heart J 2007; 28: 1462-1536.
    • (2007) Eur Heart J , vol.28 , pp. 1462-1536
    • Mancia, G.1    De Backer, G.2    Dominiczak, A.3    Cifkova, R.4    Fagard, R.5    Germano, G.6
  • 4
    • 61649119049 scopus 로고    scopus 로고
    • Metabolic syndrome and salt sensitivity of blood pressure in non-diabetic people in China: a dietary intervention study
    • Chen J, Gu D, Huang J, Rao DC, Jaquish CE, Hixson JE etal. Metabolic syndrome and salt sensitivity of blood pressure in non-diabetic people in China: a dietary intervention study. Lancet 2009; 373: 829-835.
    • (2009) Lancet , vol.373 , pp. 829-835
    • Chen, J.1    Gu, D.2    Huang, J.3    Rao, D.C.4    Jaquish, C.E.5    Hixson, J.E.6
  • 5
    • 70349249634 scopus 로고    scopus 로고
    • Effects of dietary sodium reduction on blood pressure in subjects with resistant hypertension: results from a randomized trial
    • Pimenta E, Gaddam KK, Oparil S, Aban I, Husain S, Dell'Italia LJ etal. Effects of dietary sodium reduction on blood pressure in subjects with resistant hypertension: results from a randomized trial. Hypertension 2009; 54: 475-481.
    • (2009) Hypertension , vol.54 , pp. 475-481
    • Pimenta, E.1    Gaddam, K.K.2    Oparil, S.3    Aban, I.4    Husain, S.5    Dell'Italia, L.J.6
  • 6
    • 0242525141 scopus 로고    scopus 로고
    • Influence of weight reduction on blood pressure: a meta-analysis of randomized controlled trials
    • Neter JE, Stam BE, Kok FJ, Grobbee DE, Geleijnse JM. Influence of weight reduction on blood pressure: a meta-analysis of randomized controlled trials. Hypertension 2003; 42: 878-884.
    • (2003) Hypertension , vol.42 , pp. 878-884
    • Neter, J.E.1    Stam, B.E.2    Kok, F.J.3    Grobbee, D.E.4    Geleijnse, J.M.5
  • 7
    • 79959334521 scopus 로고    scopus 로고
    • Resistant hypertension: diagnosis, evaluation, and treatment: a scientific statement from the American Heart Association Professional Education Committee of the Council for High Blood Pressure Research
    • Calhoun DA, Jones D, Textor S, Goff DC, Murphy TP, Toto RD etal. Resistant hypertension: diagnosis, evaluation, and treatment: a scientific statement from the American Heart Association Professional Education Committee of the Council for High Blood Pressure Research. Circulation 2008; 117: e510-e526.
    • (2008) Circulation , vol.117
    • Calhoun, D.A.1    Jones, D.2    Textor, S.3    Goff, D.C.4    Murphy, T.P.5    Toto, R.D.6
  • 8
    • 74549140993 scopus 로고    scopus 로고
    • Prevalence and trends in obesity among US adults, 1999-2008
    • Flegal KM, Carroll MD, Ogden CL, Curtin LR. Prevalence and trends in obesity among US adults, 1999-2008. JAMA 2010; 303: 235-241.
    • (2010) JAMA , vol.303 , pp. 235-241
    • Flegal, K.M.1    Carroll, M.D.2    Ogden, C.L.3    Curtin, L.R.4
  • 9
    • 55949118380 scopus 로고    scopus 로고
    • Association of hypertension, diabetes, dyslipidemia, and metabolic syndrome with obesity: findings from the National Health and Nutrition Examination Survey, 1999 to 2004
    • Nguyen NT, Magno CP, Lane KT, Hinojosa MW, Lane JS. Association of hypertension, diabetes, dyslipidemia, and metabolic syndrome with obesity: findings from the National Health and Nutrition Examination Survey, 1999 to 2004. J Am Coll Surg 2008; 207: 928-934.
    • (2008) J Am Coll Surg , vol.207 , pp. 928-934
    • Nguyen, N.T.1    Magno, C.P.2    Lane, K.T.3    Hinojosa, M.W.4    Lane, J.S.5
  • 10
    • 0023204243 scopus 로고
    • Incidence and precursors of hypertension in young adults: the Framingham Offspring Study
    • Garrison RJ, Kannel WB, Stokes J 3rd, Castelli WP. Incidence and precursors of hypertension in young adults: the Framingham Offspring Study. Prev Med 1987; 16: 235-251.
    • (1987) Prev Med , vol.16 , pp. 235-251
    • Garrison, R.J.1    Kannel, W.B.2    Stokes 3rd, J.3    Castelli, W.P.4
  • 11
    • 67649855154 scopus 로고    scopus 로고
    • Does greater adiposity increase blood pressure and hypertension risk?: Mendelian randomization using the FTO/MC4R genotype
    • Timpson NJ, Harbord R, Davey Smith G, Zacho J, Tybjaerg-Hansen A, Nordestgaard BG. Does greater adiposity increase blood pressure and hypertension risk?: Mendelian randomization using the FTO/MC4R genotype. Hypertension 2009; 54: 84-90.
    • (2009) Hypertension , vol.54 , pp. 84-90
    • Timpson, N.J.1    Harbord, R.2    Davey Smith, G.3    Zacho, J.4    Tybjaerg-Hansen, A.5    Nordestgaard, B.G.6
  • 14
    • 44649092702 scopus 로고    scopus 로고
    • Indices of abdominal obesity are better discriminators of cardiovascular risk factors than BMI: a meta-analysis
    • Lee CM, Huxley RR, Wildman RP, Woodward M. Indices of abdominal obesity are better discriminators of cardiovascular risk factors than BMI: a meta-analysis. J Clin Epidemiol 2008; 61: 646-653.
    • (2008) J Clin Epidemiol , vol.61 , pp. 646-653
    • Lee, C.M.1    Huxley, R.R.2    Wildman, R.P.3    Woodward, M.4
  • 15
    • 0025589490 scopus 로고
    • Body fat distribution, blood pressure, and hypertension. A prospective cohort study of men in the normative aging study
    • Cassano PA, Segal MR, Vokonas PS, Weiss ST. Body fat distribution, blood pressure, and hypertension. A prospective cohort study of men in the normative aging study. Ann Epidemiol 1990; 1: 33-48.
    • (1990) Ann Epidemiol , vol.1 , pp. 33-48
    • Cassano, P.A.1    Segal, M.R.2    Vokonas, P.S.3    Weiss, S.T.4
  • 16
    • 70449711238 scopus 로고    scopus 로고
    • Cardiovascular and metabolic predictors of progression of prehypertension into hypertension: the Strong Heart Study
    • De Marco M, de Simone G, Roman MJ, Chinali M, Lee ET, Russell M etal. Cardiovascular and metabolic predictors of progression of prehypertension into hypertension: the Strong Heart Study. Hypertension 2009; 54: 974-980.
    • (2009) Hypertension , vol.54 , pp. 974-980
    • De Marco, M.1    de Simone, G.2    Roman, M.J.3    Chinali, M.4    Lee, E.T.5    Russell, M.6
  • 18
    • 0035904776 scopus 로고    scopus 로고
    • Assessment of frequency of progression to hypertension in non-hypertensive participants in the Framingham Heart Study: a cohort study
    • Vasan RS, Larson MG, Leip EP, Kannel WB, Levy D. Assessment of frequency of progression to hypertension in non-hypertensive participants in the Framingham Heart Study: a cohort study. Lancet 2001; 358: 1682-1686.
    • (2001) Lancet , vol.358 , pp. 1682-1686
    • Vasan, R.S.1    Larson, M.G.2    Leip, E.P.3    Kannel, W.B.4    Levy, D.5
  • 19
    • 20044373510 scopus 로고    scopus 로고
    • Change in body mass index and its impact on blood pressure: a prospective population study
    • Droyvold WB, Midthjell K, Nilsen TI, Holmen J. Change in body mass index and its impact on blood pressure: a prospective population study. Int J Obes (Lond) 2005; 29: 650-655.
    • (2005) Int J Obes (Lond) , vol.29 , pp. 650-655
    • Droyvold, W.B.1    Midthjell, K.2    Nilsen, T.I.3    Holmen, J.4
  • 20
    • 60349087302 scopus 로고    scopus 로고
    • Effect of weight loss through laparoscopic gastric banding on blood pressure, plasma renin activity and aldosterone levels in morbid obesity
    • Dall'Asta C, Vedani P, Manunta P, Pizzocri P, Marchi M, Paganelli M etal. Effect of weight loss through laparoscopic gastric banding on blood pressure, plasma renin activity and aldosterone levels in morbid obesity. Nutr Metab Cardiovasc Dis 2009; 19: 110-114.
    • (2009) Nutr Metab Cardiovasc Dis , vol.19 , pp. 110-114
    • Dall'Asta, C.1    Vedani, P.2    Manunta, P.3    Pizzocri, P.4    Marchi, M.5    Paganelli, M.6
  • 21
    • 58049219012 scopus 로고    scopus 로고
    • Adipose tissue dysfunction in obesity, diabetes, and vascular diseases
    • Hajer GR, van Haeften TW, Visseren FL. Adipose tissue dysfunction in obesity, diabetes, and vascular diseases. Eur Heart J 2008; 29: 2959-2971.
    • (2008) Eur Heart J , vol.29 , pp. 2959-2971
    • Hajer, G.R.1    van Haeften, T.W.2    Visseren, F.L.3
  • 22
    • 43549114292 scopus 로고    scopus 로고
    • Mechanisms of leptin action and leptin resistance
    • Myers MG, Cowley MA, Munzberg H. Mechanisms of leptin action and leptin resistance. Annu Rev Physiol 2008; 70: 537-556.
    • (2008) Annu Rev Physiol , vol.70 , pp. 537-556
    • Myers, M.G.1    Cowley, M.A.2    Munzberg, H.3
  • 24
    • 62949144844 scopus 로고    scopus 로고
    • The adipose renin-angiotensin system: role in cardiovascular disease
    • Thatcher S, Yiannikouris F, Gupte M, Cassis L. The adipose renin-angiotensin system: role in cardiovascular disease. Mol Cell Endocrinol 2009; 302: 111-117.
    • (2009) Mol Cell Endocrinol , vol.302 , pp. 111-117
    • Thatcher, S.1    Yiannikouris, F.2    Gupte, M.3    Cassis, L.4
  • 26
    • 37349086128 scopus 로고    scopus 로고
    • Adiponectin, cardiovascular function, and hypertension
    • Wang ZV, Scherer PE. Adiponectin, cardiovascular function, and hypertension. Hypertension 2008; 51: 8-14.
    • (2008) Hypertension , vol.51 , pp. 8-14
    • Wang, Z.V.1    Scherer, P.E.2
  • 28
    • 59149084060 scopus 로고    scopus 로고
    • Endothelial dysfunction in adiponectin deficiency and its mechanisms involved
    • Cao Y, Tao L, Yuan Y, Jiao X, Lau WB, Wang Y etal. Endothelial dysfunction in adiponectin deficiency and its mechanisms involved. J Mol Cell Cardiol 2009; 46: 413-419.
    • (2009) J Mol Cell Cardiol , vol.46 , pp. 413-419
    • Cao, Y.1    Tao, L.2    Yuan, Y.3    Jiao, X.4    Lau, W.B.5    Wang, Y.6
  • 29
    • 0037020170 scopus 로고    scopus 로고
    • Role of adiponectin in preventing vascular stenosis. The missing link of adipo-vascular axis
    • Matsuda M, Shimomura I, Sata M, Arita Y, Nishida M, Maeda N etal. Role of adiponectin in preventing vascular stenosis. The missing link of adipo-vascular axis. J Biol Chem 2002; 277: 37487-37491.
    • (2002) J Biol Chem , vol.277 , pp. 37487-37491
    • Matsuda, M.1    Shimomura, I.2    Sata, M.3    Arita, Y.4    Nishida, M.5    Maeda, N.6
  • 30
    • 34249900491 scopus 로고    scopus 로고
    • Adiponectin deficiency increases leukocyte-endothelium interactions via upregulation of endothelial cell adhesion molecules in vivo
    • Ouedraogo R, Gong Y, Berzins B, Wu X, Mahadev K, Hough K etal. Adiponectin deficiency increases leukocyte-endothelium interactions via upregulation of endothelial cell adhesion molecules in vivo. J Clin Invest 2007; 117: 1718-1726.
    • (2007) J Clin Invest , vol.117 , pp. 1718-1726
    • Ouedraogo, R.1    Gong, Y.2    Berzins, B.3    Wu, X.4    Mahadev, K.5    Hough, K.6
  • 31
    • 1442327754 scopus 로고    scopus 로고
    • Hypoadiponectinemia is associated with impaired endothelium-dependent vasodilation
    • Tan KC, Xu A, Chow WS, Lam MC, Ai VH, Tam SC etal. Hypoadiponectinemia is associated with impaired endothelium-dependent vasodilation. J Clin Endocrinol Metab 2004; 89: 765-769.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 765-769
    • Tan, K.C.1    Xu, A.2    Chow, W.S.3    Lam, M.C.4    Ai, V.H.5    Tam, S.C.6
  • 32
    • 20944436777 scopus 로고    scopus 로고
    • Free fatty acid impairment of nitric oxide production in endothelial cells is mediated by IKKbeta
    • Kim F, Tysseling KA, Rice J, Pham M, Haji L, Gallis BM etal. Free fatty acid impairment of nitric oxide production in endothelial cells is mediated by IKKbeta. Arterioscler Thromb Vasc Biol 2005; 25: 989-994.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 989-994
    • Kim, F.1    Tysseling, K.A.2    Rice, J.3    Pham, M.4    Haji, L.5    Gallis, B.M.6
  • 33
    • 0033944950 scopus 로고    scopus 로고
    • Free fatty acid elevation impairs insulin-mediated vasodilation and nitric oxide production
    • Steinberg HO, Paradisi G, Hook G, Crowder K, Cronin J, Baron AD. Free fatty acid elevation impairs insulin-mediated vasodilation and nitric oxide production. Diabetes 2000; 49: 1231-1238.
    • (2000) Diabetes , vol.49 , pp. 1231-1238
    • Steinberg, H.O.1    Paradisi, G.2    Hook, G.3    Crowder, K.4    Cronin, J.5    Baron, A.D.6
  • 34
    • 77953788470 scopus 로고    scopus 로고
    • Resistin decreases expression of endothelial nitric oxide synthase through oxidative stress in human coronary artery endothelial cells
    • Chen C, Jiang J, Lu JM, Chai H, Wang X, Lin PH etal. Resistin decreases expression of endothelial nitric oxide synthase through oxidative stress in human coronary artery endothelial cells. Am J Physiol Heart Circ Physiol 2010; 299: H193-H201.
    • (2010) Am J Physiol Heart Circ Physiol , vol.299
    • Chen, C.1    Jiang, J.2    Lu, J.M.3    Chai, H.4    Wang, X.5    Lin, P.H.6
  • 35
    • 0043164953 scopus 로고    scopus 로고
    • Resistin promotes endothelial cell activation: further evidence of adipokine-endothelial interaction
    • Verma S, Li SH, Wang CH, Fedak PW, Li RK, Weisel RD etal. Resistin promotes endothelial cell activation: further evidence of adipokine-endothelial interaction. Circulation 2003; 108: 736-740.
    • (2003) Circulation , vol.108 , pp. 736-740
    • Verma, S.1    Li, S.H.2    Wang, C.H.3    Fedak, P.W.4    Li, R.K.5    Weisel, R.D.6
  • 37
    • 1242313298 scopus 로고    scopus 로고
    • Correlation between serum resistin level and adiposity in obese individuals
    • Azuma K, Katsukawa F, Oguchi S, Murata M, Yamazaki H, Shimada A etal. Correlation between serum resistin level and adiposity in obese individuals. Obes Res 2003; 11: 997-1001.
    • (2003) Obes Res , vol.11 , pp. 997-1001
    • Azuma, K.1    Katsukawa, F.2    Oguchi, S.3    Murata, M.4    Yamazaki, H.5    Shimada, A.6
  • 38
    • 0035487109 scopus 로고    scopus 로고
    • Resistin/Fizz3 expression in relation to obesity and peroxisome proliferator-activated receptor-gamma action in humans
    • Savage DB, Sewter CP, Klenk ES, Segal DG, Vidal-Puig A, Considine RV etal. Resistin/Fizz3 expression in relation to obesity and peroxisome proliferator-activated receptor-gamma action in humans. Diabetes 2001; 50: 2199-2202.
    • (2001) Diabetes , vol.50 , pp. 2199-2202
    • Savage, D.B.1    Sewter, C.P.2    Klenk, E.S.3    Segal, D.G.4    Vidal-Puig, A.5    Considine, R.V.6
  • 39
    • 34948902196 scopus 로고    scopus 로고
    • Visceral and subcutaneous adipose tissue volumes are cross-sectionally related to markers of inflammation and oxidative stress: the Framingham Heart Study
    • Pou KM, Massaro JM, Hoffmann U, Vasan RS, Maurovich-Horvat P, Larson MG etal. Visceral and subcutaneous adipose tissue volumes are cross-sectionally related to markers of inflammation and oxidative stress: the Framingham Heart Study. Circulation 2007; 116: 1234-1241.
    • (2007) Circulation , vol.116 , pp. 1234-1241
    • Pou, K.M.1    Massaro, J.M.2    Hoffmann, U.3    Vasan, R.S.4    Maurovich-Horvat, P.5    Larson, M.G.6
  • 40
    • 77956232053 scopus 로고    scopus 로고
    • Increased visceral adipose tissue mass is associated with increased C-reactive protein in patients with manifest vascular diseases
    • Faber DR, van der Graaf Y, Westerink J, Visseren FL. Increased visceral adipose tissue mass is associated with increased C-reactive protein in patients with manifest vascular diseases. Atherosclerosis 2010; 212: 274-280.
    • (2010) Atherosclerosis , vol.212 , pp. 274-280
    • Faber, D.R.1    van der Graaf, Y.2    Westerink, J.3    Visseren, F.L.4
  • 42
    • 60849129493 scopus 로고    scopus 로고
    • Loss of total and visceral adipose tissue mass predicts decreases in oxidative stress after weight-loss surgery
    • Gletsu-Miller N, Hansen JM, Jones DP, Go YM, Torres WE, Ziegler TR etal. Loss of total and visceral adipose tissue mass predicts decreases in oxidative stress after weight-loss surgery. Obesity (Silver Spring) 2009; 17: 439-446.
    • (2009) Obesity (Silver Spring) , vol.17 , pp. 439-446
    • Gletsu-Miller, N.1    Hansen, J.M.2    Jones, D.P.3    Go, Y.M.4    Torres, W.E.5    Ziegler, T.R.6
  • 43
    • 45849149991 scopus 로고    scopus 로고
    • Relations of inflammatory biomarkers and common genetic variants with arterial stiffness and wave reflection
    • Schnabel R, Larson MG, Dupuis J, Lunetta KL, Lipinska I, Meigs JB etal. Relations of inflammatory biomarkers and common genetic variants with arterial stiffness and wave reflection. Hypertension 2008; 51: 1651-1657.
    • (2008) Hypertension , vol.51 , pp. 1651-1657
    • Schnabel, R.1    Larson, M.G.2    Dupuis, J.3    Lunetta, K.L.4    Lipinska, I.5    Meigs, J.B.6
  • 44
    • 0035571399 scopus 로고    scopus 로고
    • Blood pressure and inflammation in apparently healthy men
    • Chae CU, Lee RT, Rifai N, Ridker PM. Blood pressure and inflammation in apparently healthy men. Hypertension 2001; 38: 399-403.
    • (2001) Hypertension , vol.38 , pp. 399-403
    • Chae, C.U.1    Lee, R.T.2    Rifai, N.3    Ridker, P.M.4
  • 45
    • 67651146363 scopus 로고    scopus 로고
    • Inflammatory cytokines in vascular dysfunction and vascular disease
    • Sprague AH, Khalil RA. Inflammatory cytokines in vascular dysfunction and vascular disease. Biochem Pharmacol 2009; 78: 539-552.
    • (2009) Biochem Pharmacol , vol.78 , pp. 539-552
    • Sprague, A.H.1    Khalil, R.A.2
  • 46
    • 0034704893 scopus 로고    scopus 로고
    • C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women
    • Ridker PM, Hennekens CH, Buring JE, Rifai N. C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. N Engl J Med 2000; 342: 836-843.
    • (2000) N Engl J Med , vol.342 , pp. 836-843
    • Ridker, P.M.1    Hennekens, C.H.2    Buring, J.E.3    Rifai, N.4
  • 47
    • 34047155003 scopus 로고    scopus 로고
    • Visceral fat adipokine secretion is associated with systemic inflammation in obese humans
    • Fontana L, Eagon JC, Trujillo ME, Scherer PE, Klein S. Visceral fat adipokine secretion is associated with systemic inflammation in obese humans. Diabetes 2007; 56: 1010-1013.
    • (2007) Diabetes , vol.56 , pp. 1010-1013
    • Fontana, L.1    Eagon, J.C.2    Trujillo, M.E.3    Scherer, P.E.4    Klein, S.5
  • 48
    • 33748314535 scopus 로고    scopus 로고
    • Increased infiltration of macrophages in omental adipose tissue is associated with marked hepatic lesions in morbid human obesity
    • Cancello R, Tordjman J, Poitou C, Guilhem G, Bouillot JL, Hugol D etal. Increased infiltration of macrophages in omental adipose tissue is associated with marked hepatic lesions in morbid human obesity. Diabetes 2006; 55: 1554-1561.
    • (2006) Diabetes , vol.55 , pp. 1554-1561
    • Cancello, R.1    Tordjman, J.2    Poitou, C.3    Guilhem, G.4    Bouillot, J.L.5    Hugol, D.6
  • 49
    • 0347004641 scopus 로고    scopus 로고
    • Direct reciprocal effects of resistin and adiponectin on vascular endothelial cells: a new insight into adipocytokine-endothelial cell interactions
    • Kawanami D, Maemura K, Takeda N, Harada T, Nojiri T, Imai Y etal. Direct reciprocal effects of resistin and adiponectin on vascular endothelial cells: a new insight into adipocytokine-endothelial cell interactions. Biochem Biophys Res Commun 2004; 314: 415-419.
    • (2004) Biochem Biophys Res Commun , vol.314 , pp. 415-419
    • Kawanami, D.1    Maemura, K.2    Takeda, N.3    Harada, T.4    Nojiri, T.5    Imai, Y.6
  • 50
    • 0034641647 scopus 로고    scopus 로고
    • Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-kappaB signaling through a cAMP-dependent pathway
    • Ouchi N, Kihara S, Arita Y, Okamoto Y, Maeda K, Kuriyama H etal. Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-kappaB signaling through a cAMP-dependent pathway. Circulation 2000; 102: 1296-1301.
    • (2000) Circulation , vol.102 , pp. 1296-1301
    • Ouchi, N.1    Kihara, S.2    Arita, Y.3    Okamoto, Y.4    Maeda, K.5    Kuriyama, H.6
  • 52
    • 0033158374 scopus 로고    scopus 로고
    • Visceral obesity and insulin resistance are associated with plasma aldosterone levels in women
    • Goodfriend TL, Kelley DE, Goodpaster BH, Winters SJ. Visceral obesity and insulin resistance are associated with plasma aldosterone levels in women. Obes Res 1999; 7: 355-362.
    • (1999) Obes Res , vol.7 , pp. 355-362
    • Goodfriend, T.L.1    Kelley, D.E.2    Goodpaster, B.H.3    Winters, S.J.4
  • 53
    • 64349083373 scopus 로고    scopus 로고
    • Circulating angiotensin II is associated with body fat accumulation and insulin resistance in obese subjects with type 2 diabetes mellitus
    • Saiki A, Ohira M, Endo K, Koide N, Oyama T, Murano T etal. Circulating angiotensin II is associated with body fat accumulation and insulin resistance in obese subjects with type 2 diabetes mellitus. Metabolism 2009; 58: 708-713.
    • (2009) Metabolism , vol.58 , pp. 708-713
    • Saiki, A.1    Ohira, M.2    Endo, K.3    Koide, N.4    Oyama, T.5    Murano, T.6
  • 54
    • 77956626874 scopus 로고    scopus 로고
    • Adipose tissue-specific dysregulation of angiotensinogen by oxidative stress in obesity
    • Okada S, Kozuka C, Masuzaki H, Yasue S, Ishii-Yonemoto T, Tanaka T etal. Adipose tissue-specific dysregulation of angiotensinogen by oxidative stress in obesity. Metabolism 2010; 59: 1241-1251.
    • (2010) Metabolism , vol.59 , pp. 1241-1251
    • Okada, S.1    Kozuka, C.2    Masuzaki, H.3    Yasue, S.4    Ishii-Yonemoto, T.5    Tanaka, T.6
  • 55
    • 0035650575 scopus 로고    scopus 로고
    • Adipose angiotensinogen is involved in adipose tissue growth and blood pressure regulation
    • Massiera F, Bloch-Faure M, Ceiler D, Murakami K, Fukamizu A, Gasc JM etal. Adipose angiotensinogen is involved in adipose tissue growth and blood pressure regulation. FASEB J 2001; 15: 2727-2729.
    • (2001) FASEB J , vol.15 , pp. 2727-2729
    • Massiera, F.1    Bloch-Faure, M.2    Ceiler, D.3    Murakami, K.4    Fukamizu, A.5    Gasc, J.M.6
  • 56
    • 77949654518 scopus 로고    scopus 로고
    • Adipose tissue-specific regulation of angiotensinogen in obese humans and mice: impact of nutritional status and adipocyte hypertrophy
    • Yasue S, Masuzaki H, Okada S, Ishii T, Kozuka C, Tanaka T etal. Adipose tissue-specific regulation of angiotensinogen in obese humans and mice: impact of nutritional status and adipocyte hypertrophy. Am J Hypertens 2010; 23: 425-431.
    • (2010) Am J Hypertens , vol.23 , pp. 425-431
    • Yasue, S.1    Masuzaki, H.2    Okada, S.3    Ishii, T.4    Kozuka, C.5    Tanaka, T.6
  • 57
    • 0026740639 scopus 로고
    • Tissue-specific nutritional regulation of angiotensinogen in adipose tissue
    • Frederich RC Jr, Kahn BB, Peach MJ, Flier JS. Tissue-specific nutritional regulation of angiotensinogen in adipose tissue. Hypertension 1992; 19: 339-344.
    • (1992) Hypertension , vol.19 , pp. 339-344
    • Frederich Jr., R.C.1    Kahn, B.B.2    Peach, M.J.3    Flier, J.S.4
  • 58
    • 34548207763 scopus 로고    scopus 로고
    • Multimarker approach to evaluate the incidence of the metabolic syndrome and longitudinal changes in metabolic risk factors: the Framingham Offspring Study
    • Ingelsson E, Pencina MJ, Tofler GH, Benjamin EJ, Lanier KJ, Jacques PF etal. Multimarker approach to evaluate the incidence of the metabolic syndrome and longitudinal changes in metabolic risk factors: the Framingham Offspring Study. Circulation 2007; 116: 984-992.
    • (2007) Circulation , vol.116 , pp. 984-992
    • Ingelsson, E.1    Pencina, M.J.2    Tofler, G.H.3    Benjamin, E.J.4    Lanier, K.J.5    Jacques, P.F.6
  • 59
    • 0346157984 scopus 로고    scopus 로고
    • Aldosterone antagonism attenuates obesity-induced hypertension and glomerular hyperfiltration
    • de Paula RB, da Silva AA, Hall JE. Aldosterone antagonism attenuates obesity-induced hypertension and glomerular hyperfiltration. Hypertension 2004; 43: 41-47.
    • (2004) Hypertension , vol.43 , pp. 41-47
    • de Paula, R.B.1    da Silva, A.A.2    Hall, J.E.3
  • 60
    • 0026506195 scopus 로고
    • In vitro effects of insulin on aldosterone production in rat zona glomerulosa cells
    • Petrasek D, Jensen G, Tuck M, Stern N. In vitro effects of insulin on aldosterone production in rat zona glomerulosa cells. Life Sci 1992; 50: 1781-1787.
    • (1992) Life Sci , vol.50 , pp. 1781-1787
    • Petrasek, D.1    Jensen, G.2    Tuck, M.3    Stern, N.4
  • 61
    • 34548419736 scopus 로고    scopus 로고
    • Insulin resistance and hyperinsulinemia are related to plasma aldosterone levels in hypertensive patients
    • Colussi G, Catena C, Lapenna R, Nadalini E, Chiuch A, Sechi LA. Insulin resistance and hyperinsulinemia are related to plasma aldosterone levels in hypertensive patients. Diabetes Care 2007; 30: 2349-2354.
    • (2007) Diabetes Care , vol.30 , pp. 2349-2354
    • Colussi, G.1    Catena, C.2    Lapenna, R.3    Nadalini, E.4    Chiuch, A.5    Sechi, L.A.6
  • 65
    • 63849107748 scopus 로고    scopus 로고
    • Aldosterone inhibits insulin-induced glucose uptake by degradation of insulin receptor substrate (IRS) 1 and IRS2 via a reactive oxygen species-mediated pathway in 3T3-L1 adipocytes
    • Wada T, Ohshima S, Fujisawa E, Koya D, Tsuneki H, Sasaoka T. Aldosterone inhibits insulin-induced glucose uptake by degradation of insulin receptor substrate (IRS) 1 and IRS2 via a reactive oxygen species-mediated pathway in 3T3-L1 adipocytes. Endocrinology 2009; 150: 1662-1669.
    • (2009) Endocrinology , vol.150 , pp. 1662-1669
    • Wada, T.1    Ohshima, S.2    Fujisawa, E.3    Koya, D.4    Tsuneki, H.5    Sasaoka, T.6
  • 67
    • 27744591354 scopus 로고    scopus 로고
    • Effects of dietary weight loss on sympathetic activity and cardiac risk factors associated with the metabolic syndrome
    • Straznicky NE, Lambert EA, Lambert GW, Masuo K, Esler MD, Nestel PJ. Effects of dietary weight loss on sympathetic activity and cardiac risk factors associated with the metabolic syndrome. J Clin Endocrinol Metab 2005; 90: 5998-6005.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 5998-6005
    • Straznicky, N.E.1    Lambert, E.A.2    Lambert, G.W.3    Masuo, K.4    Esler, M.D.5    Nestel, P.J.6
  • 68
    • 0028920105 scopus 로고
    • Renal denervation attenuates the sodium retention and hypertension associated with obesity
    • Kassab S, Kato T, Wilkins FC, Chen R, Hall JE, Granger JP. Renal denervation attenuates the sodium retention and hypertension associated with obesity. Hypertension 1995; 25: 893-897.
    • (1995) Hypertension , vol.25 , pp. 893-897
    • Kassab, S.1    Kato, T.2    Wilkins, F.C.3    Chen, R.4    Hall, J.E.5    Granger, J.P.6
  • 69
    • 10244267463 scopus 로고    scopus 로고
    • Effect of central and peripheral body fat distribution on sympathetic and baroreflex function in obese normotensives
    • Grassi G, Dell'Oro R, Facchini A, Quarti Trevano F, Bolla GB, Mancia G. Effect of central and peripheral body fat distribution on sympathetic and baroreflex function in obese normotensives. J Hypertens 2004; 22: 2363-2369.
    • (2004) J Hypertens , vol.22 , pp. 2363-2369
    • Grassi, G.1    Dell'Oro, R.2    Facchini, A.3    Quarti Trevano, F.4    Bolla, G.B.5    Mancia, G.6
  • 70
    • 57349086211 scopus 로고    scopus 로고
    • Influences of gender on the interaction between sympathetic nerve traffic and central adiposity
    • Tank J, Heusser K, Diedrich A, Hering D, Luft FC, Busjahn A etal. Influences of gender on the interaction between sympathetic nerve traffic and central adiposity. J Clin Endocrinol Metab 2008; 93: 4974-4978.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 4974-4978
    • Tank, J.1    Heusser, K.2    Diedrich, A.3    Hering, D.4    Luft, F.C.5    Busjahn, A.6
  • 71
    • 9644281403 scopus 로고    scopus 로고
    • Sympathetic neural activation in nondiabetic metabolic syndrome and its further augmentation by hypertension
    • Huggett RJ, Burns J, Mackintosh AF, Mary DA. Sympathetic neural activation in nondiabetic metabolic syndrome and its further augmentation by hypertension. Hypertension 2004; 44: 847-852.
    • (2004) Hypertension , vol.44 , pp. 847-852
    • Huggett, R.J.1    Burns, J.2    Mackintosh, A.F.3    Mary, D.A.4
  • 73
    • 0025029039 scopus 로고
    • Insulin and hypertension. Relationship to obesity and glucose intolerance in Pima Indians
    • Saad MF, Knowler WC, Pettitt DJ, Nelson RG, Mott DM, Bennett PH. Insulin and hypertension. Relationship to obesity and glucose intolerance in Pima Indians. Diabetes 1990; 39: 1430-1435.
    • (1990) Diabetes , vol.39 , pp. 1430-1435
    • Saad, M.F.1    Knowler, W.C.2    Pettitt, D.J.3    Nelson, R.G.4    Mott, D.M.5    Bennett, P.H.6
  • 74
    • 0033775113 scopus 로고    scopus 로고
    • Ethnic differences in insulinemia and sympathetic tone as links between obesity and blood pressure
    • Weyer C, Pratley RE, Snitker S, Spraul M, Ravussin E, Tataranni PA. Ethnic differences in insulinemia and sympathetic tone as links between obesity and blood pressure. Hypertension 2000; 36: 531-537.
    • (2000) Hypertension , vol.36 , pp. 531-537
    • Weyer, C.1    Pratley, R.E.2    Snitker, S.3    Spraul, M.4    Ravussin, E.5    Tataranni, P.A.6
  • 75
    • 33947498960 scopus 로고    scopus 로고
    • Adiponectin and resistin in human cerebrospinal fluid and expression of adiponectin receptors in the human hypothalamus
    • Kos K, Harte AL, da Silva NF, Tonchev A, Chaldakov G, James S etal. Adiponectin and resistin in human cerebrospinal fluid and expression of adiponectin receptors in the human hypothalamus. J Clin Endocrinol Metab 2007; 92: 1129-1136.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 1129-1136
    • Kos, K.1    Harte, A.L.2    da Silva, N.F.3    Tonchev, A.4    Chaldakov, G.5    James, S.6
  • 77
    • 21344432100 scopus 로고    scopus 로고
    • Role of selective leptin resistance in diet-induced obesity hypertension
    • Rahmouni K, Morgan DA, Morgan GM, Mark AL, Haynes WG. Role of selective leptin resistance in diet-induced obesity hypertension. Diabetes 2005; 54: 2012-2018.
    • (2005) Diabetes , vol.54 , pp. 2012-2018
    • Rahmouni, K.1    Morgan, D.A.2    Morgan, G.M.3    Mark, A.L.4    Haynes, W.G.5
  • 79
    • 42049103266 scopus 로고    scopus 로고
    • Endogenous melanocortin system activity contributes to the elevated arterial pressure in spontaneously hypertensive rats
    • da Silva AA, do Carmo JM, Kanyicska B, Dubinion J, Brandon E, Hall JE. Endogenous melanocortin system activity contributes to the elevated arterial pressure in spontaneously hypertensive rats. Hypertension 2008; 51: 884-890.
    • (2008) Hypertension , vol.51 , pp. 884-890
    • da Silva, A.A.1    do Carmo, J.M.2    Kanyicska, B.3    Dubinion, J.4    Brandon, E.5    Hall, J.E.6
  • 80
    • 79954701326 scopus 로고    scopus 로고
    • Ablation of the leptin receptor in the hypothalamic arcuate nucleus abrogates leptin-induced sympathetic activation
    • Harlan SM, Morgan DA, Agassandian K, Guo DF, Cassell MD, Sigmund CD etal. Ablation of the leptin receptor in the hypothalamic arcuate nucleus abrogates leptin-induced sympathetic activation. Circ Res 2011; 108: 808-812.
    • (2011) Circ Res , vol.108 , pp. 808-812
    • Harlan, S.M.1    Morgan, D.A.2    Agassandian, K.3    Guo, D.F.4    Cassell, M.D.5    Sigmund, C.D.6
  • 81
    • 2342620868 scopus 로고    scopus 로고
    • Ghrelin acts at the nucleus of the solitary tract to decrease arterial pressure in rats
    • Lin Y, Matsumura K, Fukuhara M, Kagiyama S, Fujii K, Iida M. Ghrelin acts at the nucleus of the solitary tract to decrease arterial pressure in rats. Hypertension 2004; 43: 977-982.
    • (2004) Hypertension , vol.43 , pp. 977-982
    • Lin, Y.1    Matsumura, K.2    Fukuhara, M.3    Kagiyama, S.4    Fujii, K.5    Iida, M.6
  • 82
    • 0038460863 scopus 로고    scopus 로고
    • Neural regulation of blood pressure by leptin and the related peptides
    • Matsumura K, Tsuchihashi T, Fujii K, Iida M. Neural regulation of blood pressure by leptin and the related peptides. Regul Pept 2003; 114: 79-86.
    • (2003) Regul Pept , vol.114 , pp. 79-86
    • Matsumura, K.1    Tsuchihashi, T.2    Fujii, K.3    Iida, M.4
  • 83
    • 0027953187 scopus 로고
    • Intracerebroventricular insulin produces nonuniform regional increases in sympathetic nerve activity
    • Muntzel MS, Morgan DA, Mark AL, Johnson AK. Intracerebroventricular insulin produces nonuniform regional increases in sympathetic nerve activity. Am J Physiol 1994; 267: R1350-R1355.
    • (1994) Am J Physiol , vol.267
    • Muntzel, M.S.1    Morgan, D.A.2    Mark, A.L.3    Johnson, A.K.4
  • 84
    • 33745476668 scopus 로고    scopus 로고
    • Chronic central nervous system hyperinsulinemia and regulation of arterial pressure and food intake
    • Liu J, da Silva AA, Tallam LS, Hall JE. Chronic central nervous system hyperinsulinemia and regulation of arterial pressure and food intake. J Hypertens 2006; 24: 1391-1395.
    • (2006) J Hypertens , vol.24 , pp. 1391-1395
    • Liu, J.1    da Silva, A.A.2    Tallam, L.S.3    Hall, J.E.4
  • 85
    • 0035003698 scopus 로고    scopus 로고
    • Hyperinsulinemia superimposed on insulin resistance does not elevate blood pressure
    • Verma S, Leung YM, Yao L, Battell M, Dumont AS, McNeill JH. Hyperinsulinemia superimposed on insulin resistance does not elevate blood pressure. Am J Hypertens 2001; 14: 429-432.
    • (2001) Am J Hypertens , vol.14 , pp. 429-432
    • Verma, S.1    Leung, Y.M.2    Yao, L.3    Battell, M.4    Dumont, A.S.5    McNeill, J.H.6
  • 87
    • 0029793976 scopus 로고    scopus 로고
    • Sympathetic-nerve activity before and after resection of an insulinoma
    • Scherrer U, Owlya R, Trueb L. Sympathetic-nerve activity before and after resection of an insulinoma. N Engl J Med 1996; 335: 1240-1242.
    • (1996) N Engl J Med , vol.335 , pp. 1240-1242
    • Scherrer, U.1    Owlya, R.2    Trueb, L.3
  • 88
    • 0025942184 scopus 로고
    • Effects of intravenous infusions of angiotensin II on muscle sympathetic nerve activity in humans
    • Matsukawa T, Gotoh E, Minamisawa K, Kihara M, Ueda S, Shionoiri H etal. Effects of intravenous infusions of angiotensin II on muscle sympathetic nerve activity in humans. Am J Physiol 1991; 261: R690-R696.
    • (1991) Am J Physiol , vol.261
    • Matsukawa, T.1    Gotoh, E.2    Minamisawa, K.3    Kihara, M.4    Ueda, S.5    Shionoiri, H.6
  • 89
    • 77149161113 scopus 로고    scopus 로고
    • Chronic angiotensin II infusion causes differential responses in regional sympathetic nerve activity in rats
    • Yoshimoto M, Miki K, Fink GD, King A, Osborn JW. Chronic angiotensin II infusion causes differential responses in regional sympathetic nerve activity in rats. Hypertension 2010; 55: 644-651.
    • (2010) Hypertension , vol.55 , pp. 644-651
    • Yoshimoto, M.1    Miki, K.2    Fink, G.D.3    King, A.4    Osborn, J.W.5
  • 91
    • 0041885190 scopus 로고    scopus 로고
    • Comparative effects of candesartan and hydrochlorothiazide on blood pressure, insulin sensitivity, and sympathetic drive in obese hypertensive individuals: results of the CROSS study
    • Grassi G, Seravalle G, Dell'Oro R, Trevano FQ, Bombelli M, Scopelliti F etal. Comparative effects of candesartan and hydrochlorothiazide on blood pressure, insulin sensitivity, and sympathetic drive in obese hypertensive individuals: results of the CROSS study. J Hypertens 2003; 21: 1761-1769.
    • (2003) J Hypertens , vol.21 , pp. 1761-1769
    • Grassi, G.1    Seravalle, G.2    Dell'Oro, R.3    Trevano, F.Q.4    Bombelli, M.5    Scopelliti, F.6
  • 92
    • 59649099952 scopus 로고    scopus 로고
    • Adiponectin acts in the nucleus of the solitary tract to decrease blood pressure by modulating the excitability of neuropeptide Y neurons
    • Hoyda TD, Smith PM, Ferguson AV. Adiponectin acts in the nucleus of the solitary tract to decrease blood pressure by modulating the excitability of neuropeptide Y neurons. Brain Res 2009; 1256: 76-84.
    • (2009) Brain Res , vol.1256 , pp. 76-84
    • Hoyda, T.D.1    Smith, P.M.2    Ferguson, A.V.3
  • 93
    • 33847391123 scopus 로고    scopus 로고
    • Effects of adiponectin on the renal sympathetic nerve activity and blood pressure in rats
    • Tanida M, Shen J, Horii Y, Matsuda M, Kihara S, Funahashi T etal. Effects of adiponectin on the renal sympathetic nerve activity and blood pressure in rats. Exp Biol Med (Maywood) 2007; 232: 390-397.
    • (2007) Exp Biol Med (Maywood) , vol.232 , pp. 390-397
    • Tanida, M.1    Shen, J.2    Horii, Y.3    Matsuda, M.4    Kihara, S.5    Funahashi, T.6
  • 95
    • 67650251902 scopus 로고    scopus 로고
    • Apelin gene transfer into the rostral ventrolateral medulla induces chronic blood pressure elevation in normotensive rats
    • Zhang Q, Yao F, Raizada MK, O'Rourke ST, Sun C. Apelin gene transfer into the rostral ventrolateral medulla induces chronic blood pressure elevation in normotensive rats. Circ Res 2009; 104: 1421-1428.
    • (2009) Circ Res , vol.104 , pp. 1421-1428
    • Zhang, Q.1    Yao, F.2    Raizada, M.K.3    O'Rourke, S.T.4    Sun, C.5
  • 96
    • 19944373052 scopus 로고    scopus 로고
    • The endogenous peptide apelin potently improves cardiac contractility and reduces cardiac loading in vivo
    • Ashley EA, Powers J, Chen M, Kundu R, Finsterbach T, Caffarelli A etal. The endogenous peptide apelin potently improves cardiac contractility and reduces cardiac loading in vivo. Cardiovasc Res 2005; 65: 73-82.
    • (2005) Cardiovasc Res , vol.65 , pp. 73-82
    • Ashley, E.A.1    Powers, J.2    Chen, M.3    Kundu, R.4    Finsterbach, T.5    Caffarelli, A.6
  • 97
    • 34250812741 scopus 로고    scopus 로고
    • Apelin, an APJ receptor ligand, regulates body adiposity and favors the messenger ribonucleic acid expression of uncoupling proteins in mice
    • Higuchi K, Masaki T, Gotoh K, Chiba S, Katsuragi I, Tanaka K etal. Apelin, an APJ receptor ligand, regulates body adiposity and favors the messenger ribonucleic acid expression of uncoupling proteins in mice. Endocrinology 2007; 148: 2690-2697.
    • (2007) Endocrinology , vol.148 , pp. 2690-2697
    • Higuchi, K.1    Masaki, T.2    Gotoh, K.3    Chiba, S.4    Katsuragi, I.5    Tanaka, K.6
  • 98
    • 0038460302 scopus 로고    scopus 로고
    • The seventh report of the Joint National Committee on prevention, detection, evaluation, and treatment of high blood pressure: the JNC 7 report
    • Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL etal. The seventh report of the Joint National Committee on prevention, detection, evaluation, and treatment of high blood pressure: the JNC 7 report. JAMA 2003; 289: 2560-2572.
    • (2003) JAMA , vol.289 , pp. 2560-2572
    • Chobanian, A.V.1    Bakris, G.L.2    Black, H.R.3    Cushman, W.C.4    Green, L.A.5    Izzo, J.L.6
  • 99
    • 16544378384 scopus 로고    scopus 로고
    • Effect of longer-term modest salt reduction on blood pressure
    • He FJ, MacGregor GA. Effect of longer-term modest salt reduction on blood pressure. Cochrane Database Syst Rev 2004; (3): CD004937.
    • (2004) Cochrane Database Syst Rev , Issue.3
    • He, F.J.1    MacGregor, G.A.2
  • 102
    • 1042303480 scopus 로고    scopus 로고
    • Nical in the prevention of diabetes in obese subjects (XENDOS) study: a randomized study of orlistat as an adjunct to lifestyle changes for the prevention of type 2 diabetes in obese patients
    • Torgerson JS, Hauptman J, Boldrin MN, Xe SL. Nical in the prevention of diabetes in obese subjects (XENDOS) study: a randomized study of orlistat as an adjunct to lifestyle changes for the prevention of type 2 diabetes in obese patients. Diabetes Care 2004; 27: 155-161.
    • (2004) Diabetes Care , vol.27 , pp. 155-161
    • Torgerson, J.S.1    Hauptman, J.2    Boldrin, M.N.3    Xe, S.L.4
  • 103
    • 34247222737 scopus 로고    scopus 로고
    • Optimal treatment of obesity-related hypertension: the Hypertension-Obesity-Sibutramine (HOS) study
    • Scholze J, Grimm E, Herrmann D, Unger T, Kintscher U. Optimal treatment of obesity-related hypertension: the Hypertension-Obesity-Sibutramine (HOS) study. Circulation 2007; 115: 1991-1998.
    • (2007) Circulation , vol.115 , pp. 1991-1998
    • Scholze, J.1    Grimm, E.2    Herrmann, D.3    Unger, T.4    Kintscher, U.5
  • 104
    • 32644441249 scopus 로고    scopus 로고
    • Effect of rimonabant, a cannabinoid-1 receptor blocker, on weight and cardiometabolic risk factors in overweight or obese patients: RIO-North America: a randomized controlled trial
    • Pi-Sunyer FX, Aronne LJ, Heshmati HM, Devin J, Rosenstock J. Effect of rimonabant, a cannabinoid-1 receptor blocker, on weight and cardiometabolic risk factors in overweight or obese patients: RIO-North America: a randomized controlled trial. JAMA 2006; 295: 761-775.
    • (2006) JAMA , vol.295 , pp. 761-775
    • Pi-Sunyer, F.X.1    Aronne, L.J.2    Heshmati, H.M.3    Devin, J.4    Rosenstock, J.5
  • 105
    • 17144382751 scopus 로고    scopus 로고
    • Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study
    • Van Gaal LF, Rissanen AM, Scheen AJ, Ziegler O, Rossner S. Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study. Lancet 2005; 365: 1389-1397.
    • (2005) Lancet , vol.365 , pp. 1389-1397
    • Van Gaal, L.F.1    Rissanen, A.M.2    Scheen, A.J.3    Ziegler, O.4    Rossner, S.5
  • 107
    • 34247867955 scopus 로고    scopus 로고
    • Direct Renin inhibition with aliskiren in obese patients with arterial hypertension
    • Jordan J, Engeli S, Boye SW, Le Breton S, Keefe DL. Direct Renin inhibition with aliskiren in obese patients with arterial hypertension. Hypertension 2007; 49: 1047-1055.
    • (2007) Hypertension , vol.49 , pp. 1047-1055
    • Jordan, J.1    Engeli, S.2    Boye, S.W.3    Le Breton, S.4    Keefe, D.L.5
  • 108
    • 67649763542 scopus 로고    scopus 로고
    • Aliskiren-based therapy lowers blood pressure more effectively than hydrochlorothiazide-based therapy in obese patients with hypertension: sub-analysis of a 52-week, randomized, double-blind trial
    • Schmieder RE, Philipp T, Guerediaga J, Gorostidi M, Bush C, Keefe DL. Aliskiren-based therapy lowers blood pressure more effectively than hydrochlorothiazide-based therapy in obese patients with hypertension: sub-analysis of a 52-week, randomized, double-blind trial. J Hypertens 2009; 27: 1493-1501.
    • (2009) J Hypertens , vol.27 , pp. 1493-1501
    • Schmieder, R.E.1    Philipp, T.2    Guerediaga, J.3    Gorostidi, M.4    Bush, C.5    Keefe, D.L.6
  • 109
    • 38549162093 scopus 로고    scopus 로고
    • Should we target the sympathetic nervous system in the treatment of obesity-associated hypertension?
    • Biaggioni I. Should we target the sympathetic nervous system in the treatment of obesity-associated hypertension? Hypertension 2008; 51: 168-171.
    • (2008) Hypertension , vol.51 , pp. 168-171
    • Biaggioni, I.1
  • 110
    • 33646250676 scopus 로고    scopus 로고
    • Selective imidazoline agonist moxonidine in obese hypertensive patients
    • Sanjuliani AF, de Abreu VG, Francischetti EA. Selective imidazoline agonist moxonidine in obese hypertensive patients. Int J Clin Pract 2006; 60: 621-629.
    • (2006) Int J Clin Pract , vol.60 , pp. 621-629
    • Sanjuliani, A.F.1    de Abreu, V.G.2    Francischetti, E.A.3
  • 111
    • 78649876825 scopus 로고    scopus 로고
    • Renal sympathetic denervation in patients with treatment-resistant hypertension (The Symplicity HTN-2 Trial): a randomised controlled trial
    • Esler MD, Krum H, Sobotka PA, Schlaich MP, Schmieder RE, Bohm M. Renal sympathetic denervation in patients with treatment-resistant hypertension (The Symplicity HTN-2 Trial): a randomised controlled trial. Lancet 2010; 376: 1903-1909.
    • (2010) Lancet , vol.376 , pp. 1903-1909
    • Esler, M.D.1    Krum, H.2    Sobotka, P.A.3    Schlaich, M.P.4    Schmieder, R.E.5    Bohm, M.6
  • 112
    • 79955473943 scopus 로고    scopus 로고
    • Chronic lowering of blood pressure by carotid baroreflex activation: mechanisms and potential for hypertension therapy
    • Lohmeier TE, Iliescu R. Chronic lowering of blood pressure by carotid baroreflex activation: mechanisms and potential for hypertension therapy. Hypertension 2011; 57: 880-886.
    • (2011) Hypertension , vol.57 , pp. 880-886
    • Lohmeier, T.E.1    Iliescu, R.2
  • 113
    • 78149498848 scopus 로고    scopus 로고
    • Mechanisms of adiponectin regulation and use as a pharmacological target
    • Phillips SA, Kung JT. Mechanisms of adiponectin regulation and use as a pharmacological target. Curr Opin Pharmacol 2010; 10: 676-683.
    • (2010) Curr Opin Pharmacol , vol.10 , pp. 676-683
    • Phillips, S.A.1    Kung, J.T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.