메뉴 건너뛰기




Volumn 193, Issue 1, 2014, Pages 285-294

IL-27 limits central nervous system viral clearance by promoting IL-10 and enhances demyelination

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 27; TRANSCRIPTION FACTOR FOXP3;

EID: 84903648169     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1400058     Document Type: Article
Times cited : (37)

References (58)
  • 1
    • 34247523141 scopus 로고    scopus 로고
    • Discovery and biology of IL-23 and IL-27: Related but functionally distinct regulators of inflammation
    • Kastelein, R. A., C. A. Hunter, and D. J. Cua. 2007. Discovery and biology of IL-23 and IL-27: related but functionally distinct regulators of inflammation. Annu. Rev. Immunol. 25: 221-242.
    • (2007) Annu. Rev. Immunol , vol.25 , pp. 221-242
    • Kastelein, R.A.1    Hunter, C.A.2    Cua, D.J.3
  • 3
    • 0038326688 scopus 로고    scopus 로고
    • Cutting edge: Role of IL-27/WSX-1 signaling for induction of T-bet through activation of STAT1 during initial Th1 commitment
    • Takeda, A., S. Hamano, A. Yamanaka, T. Hanada, T. Ishibashi, T. W. Mak, A. Yoshimura, and H. Yoshida. 2003. Cutting edge: role of IL-27/WSX-1 signaling for induction of T-bet through activation of STAT1 during initial Th1 commitment. J. Immunol. 170: 4886-4890.
    • (2003) J. Immunol , vol.170 , pp. 4886-4890
    • Takeda, A.1    Hamano, S.2    Yamanaka, A.3    Hanada, T.4    Ishibashi, T.5    Mak, T.W.6    Yoshimura, A.7    Yoshida, H.8
  • 4
    • 3142709474 scopus 로고    scopus 로고
    • Understanding the pro-and anti-inflammatory properties of IL-27
    • Villarino, A. V., E. Huang, and C. A. Hunter. 2004. Understanding the pro-and anti-inflammatory properties of IL-27. J. Immunol. 173: 715-720.
    • (2004) J. Immunol , vol.173 , pp. 715-720
    • Villarino, A.V.1    Huang, E.2    Hunter, C.A.3
  • 7
    • 52049111828 scopus 로고    scopus 로고
    • How interferon-g keeps autoimmune diseases in check
    • Kelchtermans, H., A. Billiau, and P. Matthys. 2008. How interferon-g keeps autoimmune diseases in check. Trends Immunol. 29: 479-486.
    • (2008) Trends Immunol , vol.29 , pp. 479-486
    • Kelchtermans, H.1    Billiau, A.2    Matthys, P.3
  • 11
  • 16
    • 14844355133 scopus 로고    scopus 로고
    • The IL-27 receptor chain WSX-1 differentially regulates antibacterial immunity and survival during experimental tuberculosis
    • Hölscher, C., A. Hölscher, D. Rückerl, T. Yoshimoto, H. Yoshida, T. Mak, C. Saris, and S. Ehlers. 2005. The IL-27 receptor chain WSX-1 differentially regulates antibacterial immunity and survival during experimental tuberculosis. J. Immunol. 174: 3534-3544.
    • (2005) J. Immunol , vol.174 , pp. 3534-3544
    • Hölscher, C.1    Hölscher, A.2    Rückerl, D.3    Yoshimoto, T.4    Yoshida, H.5    Mak, T.6    Saris, C.7    Ehlers, S.8
  • 18
    • 70349251863 scopus 로고    scopus 로고
    • Interleukin-27 inhibition of HIV-1 involves an intermediate induction of type i interferon
    • Greenwell-Wild, T., N. Vázquez, W. Jin, Z. Rangel, P. J. Munson, and S. M. Wahl. 2009. Interleukin-27 inhibition of HIV-1 involves an intermediate induction of type I interferon. Blood 114: 1864-1874.
    • (2009) Blood , vol.114 , pp. 1864-1874
    • Greenwell-Wild, T.1    Vázquez, N.2    Jin, W.3    Rangel, Z.4    Munson, P.J.5    Wahl, S.M.6
  • 21
    • 79952994082 scopus 로고    scopus 로고
    • CD4+ T cell help and innate-derived IL-27 induce Blimp-1-dependent IL-10 production by antiviral CTLs
    • Sun, J., H. Dodd, E. K. Moser, R. Sharma, and T. J. Braciale. 2011. CD4+ T cell help and innate-derived IL-27 induce Blimp-1-dependent IL-10 production by antiviral CTLs. Nat. Immunol. 12: 327-334.
    • (2011) Nat. Immunol , vol.12 , pp. 327-334
    • Sun, J.1    Dodd, H.2    Moser, E.K.3    Sharma, R.4    Braciale, T.J.5
  • 23
    • 79953222926 scopus 로고    scopus 로고
    • Highly activated cytotoxic CD8 T cells express protective IL-10 at the peak of coronavirus-induced encephalitis
    • Trandem, K., J. Zhao, E. Fleming, and S. Perlman. 2011. Highly activated cytotoxic CD8 T cells express protective IL-10 at the peak of coronavirus-induced encephalitis. J. Immunol. 186: 3642-3652.
    • (2011) J. Immunol , vol.186 , pp. 3642-3652
    • Trandem, K.1    Zhao, J.2    Fleming, E.3    Perlman, S.4
  • 24
    • 62049085168 scopus 로고    scopus 로고
    • Effector T cells control lung inflammation during acute influenza virus infection by producing IL-10
    • Sun, J., R. Madan, C. L. Karp, and T. J. Braciale. 2009. Effector T cells control lung inflammation during acute influenza virus infection by producing IL-10. Nat. Med. 15: 277-284.
    • (2009) Nat. Med , vol.15 , pp. 277-284
    • Sun, J.1    Madan, R.2    Karp, C.L.3    Braciale, T.J.4
  • 25
    • 77954085011 scopus 로고    scopus 로고
    • Interleukin-27 expression following infection with the murine gammaherpesvirus 68
    • Nelson, D. A., M. D. Tolbert, M. G. Clemens, and K. L. Bost. 2010. Interleukin-27 expression following infection with the murine gammaherpesvirus 68. Cytokine 51: 184-194.
    • (2010) Cytokine , vol.51 , pp. 184-194
    • Nelson, D.A.1    Tolbert, M.D.2    Clemens, M.G.3    Bost, K.L.4
  • 26
    • 84884351419 scopus 로고    scopus 로고
    • Cell-intrinsic IL-27 and gp130 cytokine receptor signaling regulates virus-specific CD4+ T cell responses and viral control during chronic infection
    • Harker, J. A., A. Dolgoter, and E. I. Zuniga. 2013. Cell-intrinsic IL-27 and gp130 cytokine receptor signaling regulates virus-specific CD4+ T cell responses and viral control during chronic infection. Immunity 39: 548-559.
    • (2013) Immunity , vol.39 , pp. 548-559
    • Harker, J.A.1    Dolgoter, A.2    Zuniga, E.I.3
  • 27
    • 33747588291 scopus 로고    scopus 로고
    • Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells
    • Batten, M., J. Li, S. Yi, N. M. Kljavin, D. M. Danilenko, S. Lucas, J. Lee, F. J. de Sauvage, and N. Ghilardi. 2006. Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells. Nat. Immunol. 7: 929-936.
    • (2006) Nat. Immunol , vol.7 , pp. 929-936
    • Batten, M.1    Li, J.2    Yi, S.3    Kljavin, N.M.4    Danilenko, D.M.5    Lucas, S.6    Lee, J.7    De Sauvage, F.J.8    Ghilardi, N.9
  • 28
    • 33747593830 scopus 로고    scopus 로고
    • Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system
    • Stumhofer, J. S., A. Laurence, E. H. Wilson, E. Huang, C. M. Tato, L. M. Johnson, A. V. Villarino, Q. Huang, A. Yoshimura, D. Sehy, et al. 2006. Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system. Nat. Immunol. 7: 937-945.
    • (2006) Nat. Immunol , vol.7 , pp. 937-945
    • Stumhofer, J.S.1    Laurence, A.2    Wilson, E.H.3    Huang, E.4    Tato, C.M.5    Johnson, L.M.6    Villarino, A.V.7    Huang, Q.8    Yoshimura, A.9    Sehy, D.10
  • 29
    • 36248970702 scopus 로고    scopus 로고
    • Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells
    • Fitzgerald, D. C., G. X. Zhang, M. El-Behi, Z. Fonseca-Kelly, H. Li, S. Yu, C. J. Saris, B. Gran, B. Ciric, and A. Rostami. 2007. Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells. Nat. Immunol. 8: 1372-1379.
    • (2007) Nat. Immunol , vol.8 , pp. 1372-1379
    • Fitzgerald, D.C.1    Zhang, G.X.2    El-Behi, M.3    Fonseca-Kelly, Z.4    Li, H.5    Yu, S.6    Saris, C.J.7    Gran, B.8    Ciric, B.9    Rostami, A.10
  • 30
    • 31544476315 scopus 로고    scopus 로고
    • Coronavirus infection of the central nervous system: Host-virus stand-off
    • Bergmann, C. C., T. E. Lane, and S. A. Stohlman. 2006. Coronavirus infection of the central nervous system: host-virus stand-off. Nat. Rev. Microbiol. 4: 121-132.
    • (2006) Nat. Rev. Microbiol , vol.4 , pp. 121-132
    • Bergmann, C.C.1    Lane, T.E.2    Stohlman, S.A.3
  • 31
    • 77955981696 scopus 로고    scopus 로고
    • Pathogenesis of murine coronavirus in the central nervous system
    • Bender, S. J., and S. R. Weiss. 2010. Pathogenesis of murine coronavirus in the central nervous system. J. Neuroimmune Pharmacol. 5: 336-354.
    • (2010) J. Neuroimmune Pharmacol , vol.5 , pp. 336-354
    • Bender, S.J.1    Weiss, S.R.2
  • 32
    • 84874075232 scopus 로고    scopus 로고
    • Intrathecal humoral immunity to encephalitic RNA viruses
    • Phares, T. W., S. A. Stohlman, and C. C. Bergmann. 2013. Intrathecal humoral immunity to encephalitic RNA viruses. Viruses 5: 732-752.
    • (2013) Viruses , vol.5 , pp. 732-752
    • Phares, T.W.1    Stohlman, S.A.2    Bergmann, C.C.3
  • 33
    • 44449096726 scopus 로고    scopus 로고
    • IL-10: The master regulator of immunity to infection
    • Couper, K. N., D. G. Blount, and E. M. Riley. 2008. IL-10: the master regulator of immunity to infection. J. Immunol. 180: 5771-5777.
    • (2008) J. Immunol , vol.180 , pp. 5771-5777
    • Couper, K.N.1    Blount, D.G.2    Riley, E.M.3
  • 34
    • 80052071493 scopus 로고    scopus 로고
    • Shifting hierarchies of interleukin-10-producing T cell populations in the central nervous system during acute and persistent viral encephalomyelitis
    • Puntambekar, S. S., C. C. Bergmann, C. Savarin, C. L. Karp, T. W. Phares, G. I. Parra, D. R. Hinton, and S. A. Stohlman. 2011. Shifting hierarchies of interleukin-10-producing T cell populations in the central nervous system during acute and persistent viral encephalomyelitis. J. Virol. 85: 6702-6713.
    • (2011) J. Virol , vol.85 , pp. 6702-6713
    • Puntambekar, S.S.1    Bergmann, C.C.2    Savarin, C.3    Karp, C.L.4    Phares, T.W.5    Parra, G.I.6    Hinton, D.R.7    Stohlman, S.A.8
  • 35
    • 60649110015 scopus 로고    scopus 로고
    • Role of regulatory T cells in coronavirus-induced acute encephalitis
    • Anghelina, D., J. Zhao, K. Trandem, and S. Perlman. 2009. Role of regulatory T cells in coronavirus-induced acute encephalitis. Virology 385: 358-367.
    • (2009) Virology , vol.385 , pp. 358-367
    • Anghelina, D.1    Zhao, J.2    Trandem, K.3    Perlman, S.4
  • 37
    • 84871707047 scopus 로고    scopus 로고
    • Epstein-Barr virus-induced gene 3 negatively regulates neuroinflammation and T cell activation following coronavirus-induced encephalomyelitis
    • Tirotta, E., P. Duncker, J. Oak, S. Klaus, M. R. Tsukamoto, L. Gov, and T. E. Lane. 2013. Epstein-Barr virus-induced gene 3 negatively regulates neuroinflammation and T cell activation following coronavirus-induced encephalomyelitis. J. Neuroimmunol. 254: 110-116.
    • (2013) J. Neuroimmunol , vol.254 , pp. 110-116
    • Tirotta, E.1    Duncker, P.2    Oak, J.3    Klaus, S.4    Tsukamoto, M.R.5    Gov, L.6    Lane, T.E.7
  • 38
    • 66149158158 scopus 로고    scopus 로고
    • Interleukin-12 (IL-12), but not IL-23, deficiency ameliorates viral encephalitis without affecting viral control
    • Kapil, P., R. Atkinson, C. Ramakrishna, D. J. Cua, C. C. Bergmann, and S. A. Stohlman. 2009. Interleukin-12 (IL-12), but not IL-23, deficiency ameliorates viral encephalitis without affecting viral control. J. Virol. 83: 5978-5986.
    • (2009) J. Virol , vol.83 , pp. 5978-5986
    • Kapil, P.1    Atkinson, R.2    Ramakrishna, C.3    Cua, D.J.4    Bergmann, C.C.5    Stohlman, S.A.6
  • 39
    • 0022446017 scopus 로고
    • Pathogenicity of antigenic variants of murine coronavirus JHM selected with monoclonal antibodies
    • Fleming, J. O., M. D. Trousdale, F. A. el-Zaatari, S. A. Stohlman, and L. P. Weiner. 1986. Pathogenicity of antigenic variants of murine coronavirus JHM selected with monoclonal antibodies. J. Virol. 58: 869-875.
    • (1986) J. Virol , vol.58 , pp. 869-875
    • Fleming, J.O.1    Trousdale, M.D.2    El-Zaatari, F.A.3    Stohlman, S.A.4    Weiner, L.P.5
  • 42
    • 84865321249 scopus 로고    scopus 로고
    • Oligodendroglia are limited in type i interferon induction and responsiveness in vivo
    • Kapil, P., N. B. Butchi, S. A. Stohlman, and C. C. Bergmann. 2012. Oligodendroglia are limited in type I interferon induction and responsiveness in vivo. Glia 60: 1555-1566.
    • (2012) Glia , vol.60 , pp. 1555-1566
    • Kapil, P.1    Butchi, N.B.2    Stohlman, S.A.3    Bergmann, C.C.4
  • 44
    • 36249017932 scopus 로고    scopus 로고
    • IFN-a regulates Tolllike receptor-mediated IL-27 gene expression in human macrophages
    • Pirhonen, J., J. Sirén, I. Julkunen, and S. Matikainen. 2007. IFN-a regulates Tolllike receptor-mediated IL-27 gene expression in human macrophages. J. Leukoc. Biol. 82: 1185-1192.
    • (2007) J. Leukoc. Biol , vol.82 , pp. 1185-1192
    • Pirhonen, J.1    Sirén, J.2    Julkunen, I.3    Matikainen, S.4
  • 45
    • 84857826936 scopus 로고    scopus 로고
    • CD4 T cells promote CD8 T cell immunity at the priming and effector site during viral encephalitis
    • Phares, T. W., S. A. Stohlman, M. Hwang, B. Min, D. R. Hinton, and C. C. Bergmann. 2012. CD4 T cells promote CD8 T cell immunity at the priming and effector site during viral encephalitis. J. Virol. 86: 2416-2427.
    • (2012) J. Virol , vol.86 , pp. 2416-2427
    • Phares, T.W.1    Stohlman, S.A.2    Hwang, M.3    Min, B.4    Hinton, D.R.5    Bergmann, C.C.6
  • 46
    • 0028824901 scopus 로고
    • CD8+ T-cell epitopes within the surface glycoprotein of a neurotropic coronavirus and correlation with pathogenicity
    • Castro, R. F., and S. Perlman. 1995. CD8+ T-cell epitopes within the surface glycoprotein of a neurotropic coronavirus and correlation with pathogenicity. J. Virol. 69: 8127-8131.
    • (1995) J. Virol , vol.69 , pp. 8127-8131
    • Castro, R.F.1    Perlman, S.2
  • 47
    • 0030025203 scopus 로고    scopus 로고
    • The JHM strain of mouse hepatitis virus induces a spike protein-specific Db-restricted cytotoxic T cell response
    • Bergmann, C. C., Q. Yao, M. Lin, and S. A. Stohlman. 1996. The JHM strain of mouse hepatitis virus induces a spike protein-specific Db-restricted cytotoxic T cell response. J. Gen. Virol. 77: 315-325.
    • (1996) J. Gen. Virol , vol.77 , pp. 315-325
    • Bergmann, C.C.1    Yao, Q.2    Lin, M.3    Stohlman, S.A.4
  • 48
    • 77955594335 scopus 로고    scopus 로고
    • The family of IL-10-secreting CD4+ T cells
    • Fujio, K., T. Okamura, and K. Yamamoto. 2010. The family of IL-10-secreting CD4+ T cells. Adv. Immunol. 105: 99-130.
    • (2010) Adv. Immunol , vol.105 , pp. 99-130
    • Fujio, K.1    Okamura, T.2    Yamamoto, K.3
  • 49
    • 81155160952 scopus 로고    scopus 로고
    • Type 1 regulatory T cells (Tr1) in autoimmunity
    • Pot, C., L. Apetoh, and V. K. Kuchroo. 2011. Type 1 regulatory T cells (Tr1) in autoimmunity. Semin. Immunol. 23: 202-208.
    • (2011) Semin. Immunol , vol.23 , pp. 202-208
    • Pot, C.1    Apetoh, L.2    Kuchroo, V.K.3
  • 50
    • 0037320017 scopus 로고    scopus 로고
    • Kinetics of virus-specific CD8+-T-cell expansion and trafficking following central nervous system infection
    • Marten, N. W., S. A. Stohlman, J. Zhou, and C. C. Bergmann. 2003. Kinetics of virus-specific CD8+-T-cell expansion and trafficking following central nervous system infection. J. Virol. 77: 2775-2778.
    • (2003) J. Virol , vol.77 , pp. 2775-2778
    • Marten, N.W.1    Stohlman, S.A.2    Zhou, J.3    Bergmann, C.C.4
  • 52
    • 84856554638 scopus 로고    scopus 로고
    • New directions in the basic and translational biology of interleukin-27
    • Wojno, E. D., and C. A. Hunter. 2012. New directions in the basic and translational biology of interleukin-27. Trends Immunol. 33: 91-97.
    • (2012) Trends Immunol , vol.33 , pp. 91-97
    • Wojno, E.D.1    Hunter, C.A.2
  • 54
    • 77953627758 scopus 로고    scopus 로고
    • IL-35 stimulation of CD39+ regulatory T cells confers protection against collagen II-induced arthritis via the production of IL-10
    • Kochetkova, I., S. Golden, K. Holderness, G. Callis, and D. W. Pascual. 2010. IL-35 stimulation of CD39+ regulatory T cells confers protection against collagen II-induced arthritis via the production of IL-10. J. Immunol. 184: 7144-7153.
    • (2010) J. Immunol , vol.184 , pp. 7144-7153
    • Kochetkova, I.1    Golden, S.2    Holderness, K.3    Callis, G.4    Pascual, D.W.5
  • 55
    • 79960434330 scopus 로고    scopus 로고
    • Airway inflammation and IgE production induced by dust mite allergen-specific memory/effector Th2 cell line can be effectively attenuated by IL-35
    • Huang, C. H., E. X. Loo, I. C. Kuo, G. H. Soh, D. L. Goh, B. W. Lee, and K. Y. Chua. 2011. Airway inflammation and IgE production induced by dust mite allergen-specific memory/effector Th2 cell line can be effectively attenuated by IL-35. J. Immunol. 187: 462-471.
    • (2011) J. Immunol , vol.187 , pp. 462-471
    • Huang, C.H.1    Loo, E.X.2    Kuo, I.C.3    Soh, G.H.4    Goh, D.L.5    Lee, B.W.6    Chua, K.Y.7
  • 56
    • 79953030082 scopus 로고    scopus 로고
    • Detectable expression of IL-35 in CD4+ T cells from peripheral blood of chronic hepatitis B patients
    • Liu, F., F. Tong, Y. He, and H. Liu. 2011. Detectable expression of IL-35 in CD4+ T cells from peripheral blood of chronic hepatitis B patients. Clin. Immunol. 139: 1-5.
    • (2011) Clin. Immunol , vol.139 , pp. 1-5
    • Liu, F.1    Tong, F.2    He, Y.3    Liu, H.4
  • 57
    • 79960141235 scopus 로고    scopus 로고
    • Use of cytokine immunotherapy to block CNS demyelination induced by a recombinant HSV-1 expressing IL-2
    • Zandian, M., K. R. Mott, S. J. Allen, O. Dumitrascu, J. Z. Kuo, and H. Ghiasi. 2011. Use of cytokine immunotherapy to block CNS demyelination induced by a recombinant HSV-1 expressing IL-2. Gene Ther. 18: 734-742.
    • (2011) Gene Ther , vol.18 , pp. 734-742
    • Zandian, M.1    Mott, K.R.2    Allen, S.J.3    Dumitrascu, O.4    Kuo, J.Z.5    Ghiasi, H.6
  • 58
    • 79951957824 scopus 로고    scopus 로고
    • Virus expanded regulatory T cells control disease severity in the Theiler's virus mouse model of MS
    • Richards, M. H., M. T. Getts, J. R. Podojil, Y. H. Jin, B. S. Kim, and S. D. Miller. 2011. Virus expanded regulatory T cells control disease severity in the Theiler's virus mouse model of MS. J. Autoimmun. 36: 142-154.
    • (2011) J. Autoimmun , vol.36 , pp. 142-154
    • Richards, M.H.1    Getts, M.T.2    Podojil, J.R.3    Jin, Y.H.4    Kim, B.S.5    Miller, S.D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.