Ice plant (Mesembryanthemum crystallinum) improves hyperglycaemia and memory impairments in a Wistar rat model of streptozotocin-induced diabetes

Journal of the Science of Food and Agriculture

Volumn 94, Issue 11, 2014, Pages 2266-2273

  Lee, Bao Hong ^a   Lee, Chia Chen ^a   Wu, She Ching ^a  

^a NATIONAL CHIAYI UNIVERSITY   (Taiwan)

Author keywords

Acetylcholinesterase; d pinitol; Ice plant (Mesembryanthemum crystallinum); Memory and learning abilities; Streptozotocin (STZ)

Indexed keywords

MESEMBRYANTHEMUM; MESEMBRYANTHEMUM CRYSTALLINUM; RATTUS; RATTUS NORVEGICUS;

ACETYLCHOLINESTERASE; ANTIDIABETIC AGENT; CHOLINESTERASE INHIBITOR; GLUCOSE BLOOD LEVEL; INOSITOL; MALONALDEHYDE; PINITOL; PLANT EXTRACT; SUPEROXIDE DISMUTASE;

ANALOGS AND DERIVATIVES; ANIMAL; AVOIDANCE BEHAVIOR; BLOOD; BRAIN; CHEMISTRY; COMPLICATION; DIABETES MELLITUS, EXPERIMENTAL; DRUG EFFECTS; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; MALE; MEMORY DISORDERS; MESEMBRYANTHEMUM; METABOLISM; MOUSE; OXIDATIVE STRESS; PHYTOTHERAPY; SHORT TERM MEMORY; WISTAR RAT;

ACETYLCHOLINESTERASE; ANIMALS; AVOIDANCE LEARNING; BLOOD GLUCOSE; BRAIN; CHOLINESTERASE INHIBITORS; DIABETES MELLITUS, EXPERIMENTAL; HYPERGLYCEMIA; HYPOGLYCEMIC AGENTS; INOSITOL; MALE; MALONDIALDEHYDE; MEMORY DISORDERS; MEMORY, SHORT-TERM; MESEMBRYANTHEMUM; MICE; OXIDATIVE STRESS; PHYTOTHERAPY; PLANT EXTRACTS; RATS, WISTAR; SUPEROXIDE DISMUTASE;

EID: 84903582829     PISSN: 00225142     EISSN: 10970010     Source Type: Journal    
DOI: 10.1002/jsfa.6552     Document Type: Article

References (44)

1. Hanen F, Riadh K, Samia O, Sylvain G, Christian M and Chedly A, Interspecific variability of antioxidant activities and phenolic composition in Mesembryanthemum genus. Food Chem Toxicol 47:2308-2313 (2009).
2. Vogt T, Ibdah M, Schmidt J, Wray V, Nimtz M and Strack D, Light-induced betacyanin and flavonol accumulation in bladder cells of Mesembryanthemum crystallinum. Phytochemistry 52:583-592 (1999).
3. Deters AM, Meyer U and Stintzing FC, Time-dependent bioactivity of preparations from cactus pear (Opuntia ficus indica) and ice plant (Mesembryanthemum crystallinum) on human skin fibroblasts and keratinocytes. J Ethnopharmacol 142:438-444 (2012).
4. Lin, TH, Tan TW, Tsai TH, Chen CC, Hsieh TF, Lee SS, et al., d-Pinitol inhibits prostate cancer metastasis through inhibition of alphaVbeta3 integrin by modulating FAK, c-Src and NF-kappaB pathways. Int J Mol Sci 14:9790-9802 (2013).
5. Rengarajan T, Nadakumar N and Balasubramanian MP, d-Pinitol attenuates 7, 12-dimethylbenz-[a]-anthracene induced hazards through modulating protein bound carbohydrates, adenosine triphosphatases and lysosomal enzymes during experimental mammary carcinogenesis. J Exp Ther Oncol 10:39-49 (2012).
6. Sivakumar S and Subramanian SP, Pancreatic tissue protective nature of d-pinitol studied in streptozotocin-mediated oxidative stress in experimental diabetic rats. Eur J Pharmacol 622:65-70 (2009).
7. Geethan PK and Prince PS, Antihyperlipidemic effect of d-pinitol on streptozotocin-induced diabetic Wistar rats. J Biochem Mol Toxicol 22:220-224 (2008).
8. Pitt J, Thorner M, Brautigan D, Larner J and Klein WL, Protection against the synaptic targeting and toxicity of Alzheimer's-associated Abeta oligomers by insulin mimetic chiro-inositols. FASEB J 27:199-207 (2013).
9. Artola A, Kamal A, Ramakers GM, Biessels GJ and Gispen WH, Diabetes mellitus concomitantly facilitates the induction of long-term depression and inhibits that of long-term potentiation in hippocampus. Eur J Neurosci 22:169-178 (2005).
10. Dhingra D, Parle M and Kulkarni SK, Memory enhancing activity of Glycyrrhiza glabra in mice. J Ethnopharmacol 91:361-365 (2004).
11. Sharifi AM, Mousavi SH, Farhadi M and Larijani B, Study of high glucose-induced apoptosis in PC12 cells: Role of bax protein. J Pharmacol Sci 104:258-262 (2007).
12. Delaney CL, Russell JR, Cheng HL and Feldman EL, Insulin like growth factor-I and overexpression of Bcl-xL prevent glucose-mediated apoptosis in Schwann cells. J Neuropathol Exp Neurol 60:147-160 (2001).
13. Kucukatay V, Aǧar A, Gumuslu S and Yargiçoǧlu P, Effect of sulfur dioxide on active and passive avoidance in experimental diabetes mellitus: Relation to oxidant stress and antioxidant enzymes. Int J Neurosci 117:1091-1107 (2007).
14. Lupien SB, Bluhm EJ and Ishii DN, Systemic insulin-like growth factor-I administration prevents cognitive impairment in diabetic rats, and brain IGF regulates learning/memory in normal adult rats. J Neurosci Res 74:512-523 (2003).
15. Ryan CM and Williams TM, Effects of insulin-dependent diabetes on learning and memory efficiency in adults. J Clin Exp Neuropsychol 15:685-700 (1993).
16. Baydas G, Nedzvetskii VS, Nerush PA, Kirichenko SV and Yoldas T, Altered expression of NCAM in hippocampus and cortex may underlie memory and learning deficits in rats with streptozotocin-induced diabetes mellitus. Life Sci 73:1907-1916 (2003).
17. Li ZG, Zhang W, Grunberger G and Sima AAF, Hippocampal neuronal apoptosis in type 1 diabetes. Brain Res 946:221-231 (2002).
18. Tuzcu M and Baydas G, Effect of melatonin and vitamin E on diabetes-induced learning and memory impairment in rats. Eur J Pharmacol 537:106-110 (2006).
19. Zola-Morgan SM and Squire LR, The primate hippocampal formation: evidence for a time-limited role in memory storage. Science 250:288-290 (1990).
20. Courtney SM, Petit L, Maisog JM, Ungerleider LG and Haxby JV, An area specialized for spatial working memory in human frontal cortex. Science 279:1347-1351 (1998).
21. Ma ZA, Zhao Z and Turk J, Mitochondrial dysfunction and beta-cell failure in type 2 diabetes mellitus. Exp Diabetes Res 2012:Article ID 703538 (2012).
22. Baraka A and Abdelgawad H, Targeting apoptosis in the heart of streptozotocin-induced diabetic rats. J Cardiovasc Pharmacol Therapeut 15:175-181 (2010).
23. Lee BH, Hsu WH, Liao TH and Pan TM, The Monascus metabolite monascin against TNF-alpha-induced insulin resistance via suppressing PPARgamma phosphorylation in C2C12 myotubes. Food Chem Toxicol 49:2609-2617 (2011).
24. Shi YC, Liao JW and Pan TM, Antihypertriglyceridemia and anti-inflammatory activities of Monascus-fermented dioscorea in streptozotocin-induced diabetic rats. Exp Diabetes Res 2011:Article ID710635 (2011).
25. Dhar A, Dhar I, Jiang B, Desai KM and Wu L, Chronic methylglyoxal infusion by minipump causes pancreatic β-cell dysfunction and induces type 2 diabetes in Sprague-Dawley rats. Diabetes 60:899-908 (2011).
26. Lee BH, Ho BY, Wang CT and Pan TM, Red mold rice promoted antioxidase activity against oxidative injury and improved the memory ability of zinc-deficient rats. J Agric Food Chem 57:10600-10607 (2009).
27. Morris R, Developments of a water-maze procedure for studying spatial learning in the rat. J Neurosci Method 11:47-60 (1984).
28. Buege AJ and Aus SD, Microsomal lipid peroxidation. Methods Enzymol 52:302-310 (1978).
29. Vera-Estrella R, Barkla BJ, Bohnert HJ and Pantoja O, Salt stress in Mesembryanthemum crystallinum L. cell suspensions activates adaptive mechanisms similar to those observed in the whole plant. Planta 207:426-435 (1999).
30. Sivakumar S, Palsamy P and Subramanian SP, Impact of d-pinitol on the attenuation of proinflammatory cytokines, hyperglycemia-mediated oxidative stress and protection of kidney tissue ultrastructure in streptozotocin-induced diabetic rats. Chem Biol Int 188:237-245 (2010).
31. Dang NT, Mukai R, Yoshida K and Ashida H, d-Pinitol and myo-inositol stimulate translocation of glucose transporter 4 in skeletal muscle of C57BL/6 mice. Biosci Biotechnol Biochem 74:1062-1067 (2010).
32. Morris KA, Chang Q, Mohler EQ and Gold PE, Age-related memory impairments due to reduced blood glucose responses to epinephrine. Neurobiol Aging 31:2136-2145 (2010).
33. Yang Y and Song W, Molecular links between Alzheimer's disease and diabetes mellitus. Neuroscience 250:140-150 (2013).
34. Singh R, Barden A, Mori T and Beilin L, Advanced glycation end-products: A review. Diabetologia 44:129-146 (2001).
35. Lee NH, Hsu WH, Chang YY, Kuo HF, Hsu YW and Pan TM, Ankaflavin: a natural novel PPARgamma agonist upregulates Nrf2 to attenuate methylglyoxal-induced diabetes in vivo. Free Radic Biol Med 53:2008-2016 (2012).
36. Uchida K, Khor OT, Oya T, Osawa T, Yasuda Y and Miyata T, Protein modification by a Maillard reaction intermediate methylglyoxal. Immunochemical detection of fluorescent 5-methylimidazolone derivatives in vivo. FEBS Lett 410:313-318 (1997).
37. Wang H, Meng QH, Gordon JR, Khandwala H and Wu L, Proinflammatory and proapoptotic effects of methylglyoxal on neutrophils from patients with type 2 diabetes mellitus. Clin Biochem 40:1232-1239 (2007).
38. Vincent AM, Russell JW, Low P and Feldman EL, Oxidative stress in the pathogenesis of diabetic neuropathy. Endocr Rev 25:612-628 (2004).
39. Sarter M, Hasselmo ME, Bruno JP and Givens V, Unraveling the attentional functions of cortical cholinergic inputs: Interactions between signal-driven and cognitive modulation of signal detection. Brain Res Rev 48:98-111 (2005).
40. Jazi R, Lalonde R, Qian S and Strazielle C, Regional brain evaluation of acetylcholinesterase activity in PS1/A246E transgenic mice. Neurosci Res 63:106-114 (2009).
41. Bhutada P, Mundhada Y, Bansod K, Tawari S, Patil S, Dixit P, et al., Protection of cholinergic and antioxidant system contributes to the effect of berberine ameliorating memory dysfunction in rat model of streptozotocin-induced diabetes. Behav Brain Res 220:30-41 (2011).
42. Slater TF, Overview of the methods used for detecting lipid peroxidation. Methods Enzymol 105:283-293 (1984).
43. Jafari Anarkooli I, Sankian M, Ahmadpour S, Varasteh AR and Haghir H, Evaluation of Bcl-2 family gene expression and caspase-3 activity in hippocampus STZ-induced diabetic rats. Exp Diabetes Res 2008:Article ID 638467 (2008).
44. Li XJ, Zhao BL, Liu GT and Xin WJ, Scavenging effects on active oxygen radicals by schizandrins with different structures and configurations. Free Radic Biol Med 9:99-104 (1990).