메뉴 건너뛰기




Volumn 220, Issue 1, 2011, Pages 30-41

Protection of cholinergic and antioxidant system contributes to the effect of berberine ameliorating memory dysfunction in rat model of streptozotocin-induced diabetes

Author keywords

Berberine; Dementia; Diabetes; Donepezil; Metformin; Morris water maze; Oxidative stress; Vitamin C

Indexed keywords

ASCORBIC ACID; BERBERINE; CHOLINESTERASE; DONEPEZIL; GLUTATHIONE; METFORMIN;

EID: 79952758240     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2011.01.022     Document Type: Article
Times cited : (194)

References (77)
  • 1
    • 69549138878 scopus 로고    scopus 로고
    • Impairment of synaptic plasticity and memory formation in GLP-1 receptor KO mice: interaction between type 2 diabetes and Alzheimer's disease
    • Abbas T., Faivre E., Hölscher C. Impairment of synaptic plasticity and memory formation in GLP-1 receptor KO mice: interaction between type 2 diabetes and Alzheimer's disease. Behav Brain Res 2009, 205:265-271.
    • (2009) Behav Brain Res , vol.205 , pp. 265-271
    • Abbas, T.1    Faivre, E.2    Hölscher, C.3
  • 2
    • 0028947093 scopus 로고
    • Pharmacology of memory: cholinergic-glutamatergic interactions
    • Aigner T.G. Pharmacology of memory: cholinergic-glutamatergic interactions. Curr Opin Neurobiol 1995, 5:155-160.
    • (1995) Curr Opin Neurobiol , vol.5 , pp. 155-160
    • Aigner, T.G.1
  • 3
    • 0028105940 scopus 로고
    • Non-cholinergic functions of acetylcholinesterase
    • Appleyard M.E. Non-cholinergic functions of acetylcholinesterase. Biochem Soc Trans 1994, 22:749-755.
    • (1994) Biochem Soc Trans , vol.22 , pp. 749-755
    • Appleyard, M.E.1
  • 4
    • 2442424380 scopus 로고    scopus 로고
    • Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function
    • Arvanitakis Z., Wilson R.S., Bienias J.L., Evans D.A., Bennett D.A. Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function. Arch Neurol 2004, 61:661-666.
    • (2004) Arch Neurol , vol.61 , pp. 661-666
    • Arvanitakis, Z.1    Wilson, R.S.2    Bienias, J.L.3    Evans, D.A.4    Bennett, D.A.5
  • 5
    • 0031916984 scopus 로고    scopus 로고
    • The free radical theory of aging matures
    • Beckman K.B., Ames B.N. The free radical theory of aging matures. Physiol Rev 1998, 78:547-581.
    • (1998) Physiol Rev , vol.78 , pp. 547-581
    • Beckman, K.B.1    Ames, B.N.2
  • 6
    • 77957223169 scopus 로고    scopus 로고
    • Ameliorative effect of quercetin on memory dysfunction in streptozotocin-induced diabetic rats
    • Bhutada P., Mundhada Y., Bansod K., Bhutada C., Tawari S., Dixit P., et al. Ameliorative effect of quercetin on memory dysfunction in streptozotocin-induced diabetic rats. Neurobiol Learn Mem 2010, 94:293-302.
    • (2010) Neurobiol Learn Mem , vol.94 , pp. 293-302
    • Bhutada, P.1    Mundhada, Y.2    Bansod, K.3    Bhutada, C.4    Tawari, S.5    Dixit, P.6
  • 7
    • 0037134269 scopus 로고    scopus 로고
    • Ageing and diabetes: implications for brain function
    • Biessels G.J., Heide L.P., Kamal A. Ageing and diabetes: implications for brain function. Eur J Pharmacol 2002, 441:1-14.
    • (2002) Eur J Pharmacol , vol.441 , pp. 1-14
    • Biessels, G.J.1    Heide, L.P.2    Kamal, A.3
  • 8
    • 0029821906 scopus 로고    scopus 로고
    • Place learning and hippocampal synaptic plasticity in streptozotocin-induced diabetic rats
    • Biessels G.J., Kamal A., Ramakers G.M., Urban I.J., Spruijt B.M., Erkelens D.W., et al. Place learning and hippocampal synaptic plasticity in streptozotocin-induced diabetic rats. Diabetes 1996, 45:1259-1266.
    • (1996) Diabetes , vol.45 , pp. 1259-1266
    • Biessels, G.J.1    Kamal, A.2    Ramakers, G.M.3    Urban, I.J.4    Spruijt, B.M.5    Erkelens, D.W.6
  • 9
    • 0032572613 scopus 로고    scopus 로고
    • Water maze learning and hippocampal synaptic plasticity in streptozotocin-diabetic rats: effects of insulin treatment
    • Biessels G.J., Kamal A., Urban I.J., Spruijt B.M., Erkelens D.W., Gispen W.H. Water maze learning and hippocampal synaptic plasticity in streptozotocin-diabetic rats: effects of insulin treatment. Brain Res 1998, 800:125-135.
    • (1998) Brain Res , vol.800 , pp. 125-135
    • Biessels, G.J.1    Kamal, A.2    Urban, I.J.3    Spruijt, B.M.4    Erkelens, D.W.5    Gispen, W.H.6
  • 12
    • 33744815213 scopus 로고    scopus 로고
    • Place learning in Morris water task: making the memory stick
    • Bolding K., Rudy J.W. Place learning in Morris water task: making the memory stick. Learning & Memory 2006, 13:278-286.
    • (2006) Learning & Memory , vol.13 , pp. 278-286
    • Bolding, K.1    Rudy, J.W.2
  • 14
  • 15
    • 0035195970 scopus 로고    scopus 로고
    • Vascular factors and metabolic interactions in the pathogenesis of diabetic neuropathy
    • Cameron N.E., Eaton S.E.M., Cotter M.A., Tesfaye S. Vascular factors and metabolic interactions in the pathogenesis of diabetic neuropathy. Diabetologia 2001, 44:1450-1458.
    • (2001) Diabetologia , vol.44 , pp. 1450-1458
    • Cameron, N.E.1    Eaton, S.E.M.2    Cotter, M.A.3    Tesfaye, S.4
  • 16
    • 65049091228 scopus 로고    scopus 로고
    • Cognitive decline and dementia in diabetes-systematic overview of prospective observational studies
    • Cukierman T., Gerstein H.C., Williamson J.D. Cognitive decline and dementia in diabetes-systematic overview of prospective observational studies. J Diabet 2005, 48:12-19.
    • (2005) J Diabet , vol.48 , pp. 12-19
    • Cukierman, T.1    Gerstein, H.C.2    Williamson, J.D.3
  • 17
    • 0141461415 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 receptor is involved in learning and neuroprotection
    • During M.J., Cao L., Zuzga D.S., Francis J.S., Fitzsimons H.L., Jiao X., et al. Glucagon-like peptide-1 receptor is involved in learning and neuroprotection. Nat Med 2003, 9:1173-1179.
    • (2003) Nat Med , vol.9 , pp. 1173-1179
    • During, M.J.1    Cao, L.2    Zuzga, D.S.3    Francis, J.S.4    Fitzsimons, H.L.5    Jiao, X.6
  • 18
    • 3042934967 scopus 로고
    • Tissue sulfhydryl groups
    • Ellman G.L. Tissue sulfhydryl groups. Arch Biochem Biophys 1959, 82:70-77.
    • (1959) Arch Biochem Biophys , vol.82 , pp. 70-77
    • Ellman, G.L.1
  • 20
    • 0036796875 scopus 로고    scopus 로고
    • Oxidative stress and tress activated signaling pathways: a unifying hypothesis of type 2 diabetes
    • Evans J.L., Goldfine I.D., Maddux B.A., Grodsky G.M. Oxidative stress and tress activated signaling pathways: a unifying hypothesis of type 2 diabetes. Endocr Rev 2002, 23:599-622.
    • (2002) Endocr Rev , vol.23 , pp. 599-622
    • Evans, J.L.1    Goldfine, I.D.2    Maddux, B.A.3    Grodsky, G.M.4
  • 21
    • 0035032925 scopus 로고    scopus 로고
    • Impairment of learning and memory in rats caused by oxidative stress and aging, and changes in antioxidative defense systems
    • Fukui K., Onodera K., Shinkai T., Suzuki S., Urano S. Impairment of learning and memory in rats caused by oxidative stress and aging, and changes in antioxidative defense systems. Ann NY Acad Sci 2001, 928:168-175.
    • (2001) Ann NY Acad Sci , vol.928 , pp. 168-175
    • Fukui, K.1    Onodera, K.2    Shinkai, T.3    Suzuki, S.4    Urano, S.5
  • 22
    • 0028947094 scopus 로고
    • Ageing: the cholinergic hypothesis of cognitive decline
    • Gallagher M., Colombo P.J. Ageing: the cholinergic hypothesis of cognitive decline. Curr Opin Neurobiol 1995, 5:161-168.
    • (1995) Curr Opin Neurobiol , vol.5 , pp. 161-168
    • Gallagher, M.1    Colombo, P.J.2
  • 23
    • 0034333018 scopus 로고    scopus 로고
    • Cognition and synaptic plasticity in diabetes mellitus
    • Gispen W.H., Biessels G.J. Cognition and synaptic plasticity in diabetes mellitus. Trends Neurosci 2000, 23:542-549.
    • (2000) Trends Neurosci , vol.23 , pp. 542-549
    • Gispen, W.H.1    Biessels, G.J.2
  • 24
    • 77949336458 scopus 로고    scopus 로고
    • Effect of traditional Chinese medicine berberine on type 2 diabetes based on comprehensive metabonomics
    • Gu Y., Zhang Y., Shi X., Li X., Hong J., Chen J., et al. Effect of traditional Chinese medicine berberine on type 2 diabetes based on comprehensive metabonomics. Talanta 2010, 81:766-772.
    • (2010) Talanta , vol.81 , pp. 766-772
    • Gu, Y.1    Zhang, Y.2    Shi, X.3    Li, X.4    Hong, J.5    Chen, J.6
  • 25
    • 77952550377 scopus 로고    scopus 로고
    • Effects of combined treatment with vitamins C and E on passive avoidance learning and memory in diabetic rats
    • Hasanein P., Shahidi S. Effects of combined treatment with vitamins C and E on passive avoidance learning and memory in diabetic rats. Neurobiol Learn Mem 2010, 93:472-478.
    • (2010) Neurobiol Learn Mem , vol.93 , pp. 472-478
    • Hasanein, P.1    Shahidi, S.2
  • 26
    • 0031928535 scopus 로고    scopus 로고
    • Is sporadic Alzheimer disease the brain type of non-insulin dependent diabetes mellitus? A challenging hypothesis
    • Hoyer S. Is sporadic Alzheimer disease the brain type of non-insulin dependent diabetes mellitus? A challenging hypothesis. J Neural Transm 1998, 105:412-422.
    • (1998) J Neural Transm , vol.105 , pp. 412-422
    • Hoyer, S.1
  • 27
    • 75149165246 scopus 로고    scopus 로고
    • Synthesis, biological evaluation, and molecular modeling of berberine derivatives as potent acetylcholinesterase inhibitors
    • Huang L., Shi A., He F., Li X. Synthesis, biological evaluation, and molecular modeling of berberine derivatives as potent acetylcholinesterase inhibitors. Bioorg Med Chem 2010, 18(3):1244-1251.
    • (2010) Bioorg Med Chem , vol.18 , Issue.3 , pp. 1244-1251
    • Huang, L.1    Shi, A.2    He, F.3    Li, X.4
  • 28
    • 50149108987 scopus 로고    scopus 로고
    • Pharmacological and therapeutic effects of Berberis vulgaris and its active constituent, berberine
    • Imanshahidi M., Hosseinzadeh H. Pharmacological and therapeutic effects of Berberis vulgaris and its active constituent, berberine. Phytother Res 2008, 22:999-1012.
    • (2008) Phytother Res , vol.22 , pp. 999-1012
    • Imanshahidi, M.1    Hosseinzadeh, H.2
  • 29
    • 2342536173 scopus 로고    scopus 로고
    • Learning and hippocampal synaptic plasticity in streptozotocin-diabetic rats: interaction of diabetes and ageing
    • Kamal A., Biessels G.J., Duis S.E., Gispen W.H. Learning and hippocampal synaptic plasticity in streptozotocin-diabetic rats: interaction of diabetes and ageing. Diabetologia 2000, 43:500-506.
    • (2000) Diabetologia , vol.43 , pp. 500-506
    • Kamal, A.1    Biessels, G.J.2    Duis, S.E.3    Gispen, W.H.4
  • 30
    • 16644385507 scopus 로고    scopus 로고
    • Acetylcholinesterase inhibitors from the aerial parts of Corydalis speciosa
    • Kim D.K., Lee K.T., Baek N.I., Kim S.H., Park H.W., Lim J.P., et al. Acetylcholinesterase inhibitors from the aerial parts of Corydalis speciosa. Arch Pharm Res 2004, 27:1127-1131.
    • (2004) Arch Pharm Res , vol.27 , pp. 1127-1131
    • Kim, D.K.1    Lee, K.T.2    Baek, N.I.3    Kim, S.H.4    Park, H.W.5    Lim, J.P.6
  • 31
    • 0037224041 scopus 로고    scopus 로고
    • Treadmill exercise increase cell proliferation in dentate gyrus of rats with streptozotocin-induced diabetes
    • Kim H.B., Jang M.H., Shin M., Lim B.V., Kim Y.P., Kim K.J., et al. Treadmill exercise increase cell proliferation in dentate gyrus of rats with streptozotocin-induced diabetes. J Diabetes Complications 2003, 17:23-29.
    • (2003) J Diabetes Complications , vol.17 , pp. 23-29
    • Kim, H.B.1    Jang, M.H.2    Shin, M.3    Lim, B.V.4    Kim, Y.P.5    Kim, K.J.6
  • 32
    • 0035830396 scopus 로고    scopus 로고
    • Cardiovascular risk factors and cognitive decline in middle-aged adults
    • Knopman D.S., Boland L.L., Mosley T., Howard G., Liao D., Szklo M., et al. Cardiovascular risk factors and cognitive decline in middle-aged adults. Neurology 2001, 56:42-48.
    • (2001) Neurology , vol.56 , pp. 42-48
    • Knopman, D.S.1    Boland, L.L.2    Mosley, T.3    Howard, G.4    Liao, D.5    Szklo, M.6
  • 33
    • 46449094796 scopus 로고    scopus 로고
    • Lycopene attenuates diabetes-associated cognitive decline in rats
    • Kuhad A., Sethi R., Chopra K. Lycopene attenuates diabetes-associated cognitive decline in rats. Life Sci 2008, 83:128-134.
    • (2008) Life Sci , vol.83 , pp. 128-134
    • Kuhad, A.1    Sethi, R.2    Chopra, K.3
  • 34
    • 77349115762 scopus 로고    scopus 로고
    • Berberine: a plant alkaloid with therapeutic potential for central nervous system disorders
    • Kulkarni S.K., Dhir A. Berberine: a plant alkaloid with therapeutic potential for central nervous system disorders. Phytother Res 2010, 24:317-324.
    • (2010) Phytother Res , vol.24 , pp. 317-324
    • Kulkarni, S.K.1    Dhir, A.2
  • 35
    • 0032856319 scopus 로고    scopus 로고
    • Glucose transport in brain and retina: implications in the management and complications of diabetes
    • Kumagai A.K. Glucose transport in brain and retina: implications in the management and complications of diabetes. Diabetes Metab Res Rev 1999, 15:261-273.
    • (1999) Diabetes Metab Res Rev , vol.15 , pp. 261-273
    • Kumagai, A.K.1
  • 36
    • 33749336146 scopus 로고    scopus 로고
    • Berberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin-resistant states
    • Lee Y.S., Kim W.S., Kim K.H., Yoon M.J., Cho H.J., Shen Y., et al. Berberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin-resistant states. Diabetes 2006, 55:2256-2264.
    • (2006) Diabetes , vol.55 , pp. 2256-2264
    • Lee, Y.S.1    Kim, W.S.2    Kim, K.H.3    Yoon, M.J.4    Cho, H.J.5    Shen, Y.6
  • 37
    • 1842708890 scopus 로고    scopus 로고
    • Therapeutic effects of berberine in impaired glucose tolerance rats and its influence on insulin secretion
    • Leng S.H., Lu F.E., Xu L.J. Therapeutic effects of berberine in impaired glucose tolerance rats and its influence on insulin secretion. Acta Pharmacol Sin 2004, 4:496-502.
    • (2004) Acta Pharmacol Sin , vol.4 , pp. 496-502
    • Leng, S.H.1    Lu, F.E.2    Xu, L.J.3
  • 38
    • 36448936053 scopus 로고    scopus 로고
    • Common pathological processes in Alzheimer disease and type 2 diabetes: a review
    • Li L., Hölscher C. Common pathological processes in Alzheimer disease and type 2 diabetes: a review. Brain Res Rev 2007, 56:384-402.
    • (2007) Brain Res Rev , vol.56 , pp. 384-402
    • Li, L.1    Hölscher, C.2
  • 39
    • 44949179681 scopus 로고    scopus 로고
    • Berberine inhibits aldose reductase and oxidative stress in rat mesangial cells cultured under high glucose
    • Liu W., Liu P., Tao S., Deng Y., Li X., Lan T., et al. Berberine inhibits aldose reductase and oxidative stress in rat mesangial cells cultured under high glucose. Arch Biochem Biophys 2008, 475:128-134.
    • (2008) Arch Biochem Biophys , vol.475 , pp. 128-134
    • Liu, W.1    Liu, P.2    Tao, S.3    Deng, Y.4    Li, X.5    Lan, T.6
  • 41
    • 0037459810 scopus 로고    scopus 로고
    • Angiotensin converting enzyme inhibition partially prevents deficits in water maze performance, hippocampal synaptic plasticity and cerebral blood flow in streptozotocin-diabetic rats
    • Manschot S.M., Biessels J.G., Cameron N.E., Cotter M.A., Kamal A., Kappelle L.J., et al. Angiotensin converting enzyme inhibition partially prevents deficits in water maze performance, hippocampal synaptic plasticity and cerebral blood flow in streptozotocin-diabetic rats. Brain Res 2003, 966:274-282.
    • (2003) Brain Res , vol.966 , pp. 274-282
    • Manschot, S.M.1    Biessels, J.G.2    Cameron, N.E.3    Cotter, M.A.4    Kamal, A.5    Kappelle, L.J.6
  • 43
    • 1842684425 scopus 로고    scopus 로고
    • Cerebral glucose metabolism in diabetes mellitus
    • McCall A.L. Cerebral glucose metabolism in diabetes mellitus. Eur J Pharmacol 2004, 490:147-158.
    • (2004) Eur J Pharmacol , vol.490 , pp. 147-158
    • McCall, A.L.1
  • 44
    • 0027749479 scopus 로고
    • The neuropharmacological and neurochemical basis of place learning in the Morris water maze
    • McNamara R.K., Skelton R.W. The neuropharmacological and neurochemical basis of place learning in the Morris water maze. Brain Res Brain Res Rev 1993, 59:193-204.
    • (1993) Brain Res Brain Res Rev , vol.59 , pp. 193-204
    • McNamara, R.K.1    Skelton, R.W.2
  • 45
    • 28444433338 scopus 로고    scopus 로고
    • Impact of impaired glucose tolerance and type 2 diabetes on cognitive aging
    • 26S
    • Messier C. Impact of impaired glucose tolerance and type 2 diabetes on cognitive aging. Neurobiol Aging 2005, S26-S30. 26S.
    • (2005) Neurobiol Aging
    • Messier, C.1
  • 46
    • 0019957779 scopus 로고
    • Place navigation impaired in rats with hippocampal lesions
    • Morris R.G., Garrud P., Rawlins J.N., O'Keefe J. Place navigation impaired in rats with hippocampal lesions. Nature 1982, 297:681-683.
    • (1982) Nature , vol.297 , pp. 681-683
    • Morris, R.G.1    Garrud, P.2    Rawlins, J.N.3    O'Keefe, J.4
  • 47
    • 0034643340 scopus 로고    scopus 로고
    • Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage
    • Nishikawa T., Edelstein D., Du X.L., Yamagishi S., Matsumura T., Kaneda Y., et al. Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage. Nature 2000, 404:787-790.
    • (2000) Nature , vol.404 , pp. 787-790
    • Nishikawa, T.1    Edelstein, D.2    Du, X.L.3    Yamagishi, S.4    Matsumura, T.5    Kaneda, Y.6
  • 48
    • 32244434961 scopus 로고    scopus 로고
    • Therapy insight: the impact of type 1 diabetes on brain development and function
    • Northam E., Rankins D., Cameron F.J. Therapy insight: the impact of type 1 diabetes on brain development and function. Nat Clin Pract Neurol 2006, 2:78-86.
    • (2006) Nat Clin Pract Neurol , vol.2 , pp. 78-86
    • Northam, E.1    Rankins, D.2    Cameron, F.J.3
  • 49
    • 64749088646 scopus 로고    scopus 로고
    • Central nervous system functions in youth with type 1 diabetes 12 years after disease onset
    • Northam E.A., Rankins D., Lin A., Wellard R.M., Pell G.S., Finch S.J., et al. Central nervous system functions in youth with type 1 diabetes 12 years after disease onset. Diabetes Care 2009, 32:445-450.
    • (2009) Diabetes Care , vol.32 , pp. 445-450
    • Northam, E.A.1    Rankins, D.2    Lin, A.3    Wellard, R.M.4    Pell, G.S.5    Finch, S.J.6
  • 50
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
    • Ohkawa H., Ohishi N., Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979, 95:351-358.
    • (1979) Anal Biochem , vol.95 , pp. 351-358
    • Ohkawa, H.1    Ohishi, N.2    Yagi, K.3
  • 51
    • 0030856703 scopus 로고    scopus 로고
    • Effect of long-term administration of berberine on scopolamine-induced amnesia in rats
    • Peng W.H., Hsieh M.T., Wu C.R. Effect of long-term administration of berberine on scopolamine-induced amnesia in rats. Jpn J Pharmacol 1997, 74:261-266.
    • (1997) Jpn J Pharmacol , vol.74 , pp. 261-266
    • Peng, W.H.1    Hsieh, M.T.2    Wu, C.R.3
  • 52
    • 0034939115 scopus 로고    scopus 로고
    • The role of oxidative stress in the onset and progression of diabetes and its complications: a summary of a congress series sponsored by UNESCO-MCBN, the American diabetes association, and the German diabetes society
    • R̈oosen P., Nawroth P.P., King G., M̈oller W., Tritschler H.J., Packer L. The role of oxidative stress in the onset and progression of diabetes and its complications: a summary of a congress series sponsored by UNESCO-MCBN, the American diabetes association, and the German diabetes society. Diabetes Metab Res Rev 2001, 17:189-212.
    • (2001) Diabetes Metab Res Rev , vol.17 , pp. 189-212
    • R̈oosen, P.1    Nawroth, P.P.2    King, G.3    M̈oller, W.4    Tritschler, H.J.5    Packer, L.6
  • 53
    • 77953056996 scopus 로고    scopus 로고
    • Morning cortisol levels and cognitive abilities in people with type 2 diabetes: the Edinburgh Type 2 Diabetes Study
    • Reynolds R.M., Strachan M.W., Labad J., Lee A.J., Frier B.M., Fowkes F.G., et al. Morning cortisol levels and cognitive abilities in people with type 2 diabetes: the Edinburgh Type 2 Diabetes Study. Diabetes Care 2010, 33:714-720.
    • (2010) Diabetes Care , vol.33 , pp. 714-720
    • Reynolds, R.M.1    Strachan, M.W.2    Labad, J.3    Lee, A.J.4    Frier, B.M.5    Fowkes, F.G.6
  • 56
    • 0343962228 scopus 로고    scopus 로고
    • Effect of streptozotocin-induced diabetes on activities of cholinesterases in the rat retina
    • Sánchez-Chávez G., Salceda R. Effect of streptozotocin-induced diabetes on activities of cholinesterases in the rat retina. IUBMB Life 2000, 49:283-287.
    • (2000) IUBMB Life , vol.49 , pp. 283-287
    • Sánchez-Chávez, G.1    Salceda, R.2
  • 57
    • 65049090141 scopus 로고    scopus 로고
    • Resveratrol prevents memory deficits and the increase in acetylcholinesterase activity in streptozotocin-induced diabetic rats
    • Schmatz R., Mazzanti C.M., Spanevello R., Stefanello N., Gutierres J., Corrêa M., et al. Resveratrol prevents memory deficits and the increase in acetylcholinesterase activity in streptozotocin-induced diabetic rats. Eur J Pharmacol 2009, 610:42-48.
    • (2009) Eur J Pharmacol , vol.610 , pp. 42-48
    • Schmatz, R.1    Mazzanti, C.M.2    Spanevello, R.3    Stefanello, N.4    Gutierres, J.5    Corrêa, M.6
  • 58
    • 1842785176 scopus 로고    scopus 로고
    • Insulin C-peptide, hyperglycemia, and central nervous system complications in diabetes
    • Sima A.A.F., Kamiya H., Lia Z.G. Insulin C-peptide, hyperglycemia, and central nervous system complications in diabetes. Eur J Pharmacol 2004, 490:187-197.
    • (2004) Eur J Pharmacol , vol.490 , pp. 187-197
    • Sima, A.A.F.1    Kamiya, H.2    Lia, Z.G.3
  • 59
    • 33646118236 scopus 로고    scopus 로고
    • Soluble semicarbazide-sensitive amine oxidase (SSAO) activity is related to oxidative stress and subchronic inflammation in streptozotocin-induced diabetic rats
    • Somfai G.M., Knippel B., Ruzicska E., Stadler K., Tóth M., Salacz G., et al. Soluble semicarbazide-sensitive amine oxidase (SSAO) activity is related to oxidative stress and subchronic inflammation in streptozotocin-induced diabetic rats. Neurochem Int 2006, 48:746-752.
    • (2006) Neurochem Int , vol.48 , pp. 746-752
    • Somfai, G.M.1    Knippel, B.2    Ruzicska, E.3    Stadler, K.4    Tóth, M.5    Salacz, G.6
  • 61
    • 33749327046 scopus 로고    scopus 로고
    • Effects of berberine on diabetes induced by alloxan and a high-fat/high-cholesterol diet in rats
    • Tang L.Q., Wei W., Chen L.M., Liu S. Effects of berberine on diabetes induced by alloxan and a high-fat/high-cholesterol diet in rats. J Ethnopharmacol 2006, 108:109-115.
    • (2006) J Ethnopharmacol , vol.108 , pp. 109-115
    • Tang, L.Q.1    Wei, W.2    Chen, L.M.3    Liu, S.4
  • 62
    • 67649295306 scopus 로고    scopus 로고
    • Chronic treatment with tocotrienol, an isoform of vitamin E, prevents intracerebroventricular streptozotocin-induced cognitive impairment and oxidative-nitrosative stress in rats
    • Tiwari V., Kuhad A., Bishnoi M., Chopra K. Chronic treatment with tocotrienol, an isoform of vitamin E, prevents intracerebroventricular streptozotocin-induced cognitive impairment and oxidative-nitrosative stress in rats. Pharmacol Biochem Behav 2009, 93:183-189.
    • (2009) Pharmacol Biochem Behav , vol.93 , pp. 183-189
    • Tiwari, V.1    Kuhad, A.2    Bishnoi, M.3    Chopra, K.4
  • 63
    • 33646161716 scopus 로고    scopus 로고
    • Effect of melatonin and vitamin E on diabetes-induced learning and memory impairment in rats
    • Tuzcu M., Baydas G. Effect of melatonin and vitamin E on diabetes-induced learning and memory impairment in rats. Eur J Pharmacol 2006, 537:106-110.
    • (2006) Eur J Pharmacol , vol.537 , pp. 106-110
    • Tuzcu, M.1    Baydas, G.2
  • 64
    • 59349087727 scopus 로고    scopus 로고
    • Gastrointestinal dysfunction in diabetic rats relates with a decline in tissue l-arginine content and consequent low levels of nitric oxide
    • Umathe S.N., Kochar N.I., Jain N.S., Dixit P.V. Gastrointestinal dysfunction in diabetic rats relates with a decline in tissue l-arginine content and consequent low levels of nitric oxide. Nitric Oxide 2009, 20:129-133.
    • (2009) Nitric Oxide , vol.20 , pp. 129-133
    • Umathe, S.N.1    Kochar, N.I.2    Jain, N.S.3    Dixit, P.V.4
  • 65
    • 64249141005 scopus 로고    scopus 로고
    • Type 2 diabetes mellitus, hypertension, dyslipidemia and obesity: a systematic comparison of their impact on cognition
    • van den Berg E., Kloppenborg R.P., Kessels R.P.C., Kappelle L.J., Biessels G.J. Type 2 diabetes mellitus, hypertension, dyslipidemia and obesity: a systematic comparison of their impact on cognition. Biochim et Biophys Acta 2009, 1792:470-481.
    • (2009) Biochim et Biophys Acta , vol.1792 , pp. 470-481
    • van den Berg, E.1    Kloppenborg, R.P.2    Kessels, R.P.C.3    Kappelle, L.J.4    Biessels, G.J.5
  • 67
    • 0030963670 scopus 로고    scopus 로고
    • Recent progress in advanced glycation end products and diabetic complications
    • Vlassara H. Recent progress in advanced glycation end products and diabetic complications. Diabetes 1997, 46:S19-S37.
    • (1997) Diabetes , vol.46
    • Vlassara, H.1
  • 68
    • 70349157209 scopus 로고    scopus 로고
    • Ameliorative effect of berberine on endothelial dysfunction in diabetic rats induced by high-fat diet and streptozotocin
    • Wang C., Li J., Lu X., Zhang M., Song Y., Chen L., et al. Ameliorative effect of berberine on endothelial dysfunction in diabetic rats induced by high-fat diet and streptozotocin. Eur J Pharmacol 2009, 620:131-137.
    • (2009) Eur J Pharmacol , vol.620 , pp. 131-137
    • Wang, C.1    Li, J.2    Lu, X.3    Zhang, M.4    Song, Y.5    Chen, L.6
  • 69
    • 0028884081 scopus 로고
    • Protein ligand interactions Part 5: isoquinoline alkaloids as inhibitors of acetylcholinesterase from Electrophorus electricus
    • Whiteley C.G., Daya S. Protein ligand interactions Part 5: isoquinoline alkaloids as inhibitors of acetylcholinesterase from Electrophorus electricus. J Enzyme Inhib 1995, 9:285-294.
    • (1995) J Enzyme Inhib , vol.9 , pp. 285-294
    • Whiteley, C.G.1    Daya, S.2
  • 70
    • 0037014581 scopus 로고    scopus 로고
    • Cerebral white matter lesions, retinopathy, and incident clinical stroke
    • Wong T.Y., Klein R., Sharrett A.R., Couper D.J., Klein B.E.K., Liao D.P., et al. Cerebral white matter lesions, retinopathy, and incident clinical stroke. JAMA 2002, 288:67-74.
    • (2002) JAMA , vol.288 , pp. 67-74
    • Wong, T.Y.1    Klein, R.2    Sharrett, A.R.3    Couper, D.J.4    Klein, B.E.K.5    Liao, D.P.6
  • 71
    • 64249121164 scopus 로고    scopus 로고
    • A look inside the diabetic brain: contributors to diabetes-induced brain aging
    • Wrighten S.A., Piroli G.G., Grillo C.A., Reagan L.P. A look inside the diabetic brain: contributors to diabetes-induced brain aging. Biochim et Biophys Acta 2009, 1792:444-453.
    • (2009) Biochim et Biophys Acta , vol.1792 , pp. 444-453
    • Wrighten, S.A.1    Piroli, G.G.2    Grillo, C.A.3    Reagan, L.P.4
  • 72
    • 42949145899 scopus 로고    scopus 로고
    • Efficacy of berberine in patients with type 2 diabetes mellitus
    • Yin J., Xing H., Ye J Efficacy of berberine in patients with type 2 diabetes mellitus. Metabolism 2008, 57:712-717.
    • (2008) Metabolism , vol.57 , pp. 712-717
    • Yin, J.1    Xing, H.2    Ye, J.3
  • 73
    • 77449089475 scopus 로고    scopus 로고
    • Modulation of glucagon-like peptide-1 release by berberine: in vivo and in vitro studies
    • Yu Y., Liu L., Wang X., Liu X., Liu X., Xie L., et al. Modulation of glucagon-like peptide-1 release by berberine: in vivo and in vitro studies. Biochem Pharmacol 2010, 79:1000-1006.
    • (2010) Biochem Pharmacol , vol.79 , pp. 1000-1006
    • Yu, Y.1    Liu, L.2    Wang, X.3    Liu, X.4    Liu, X.5    Xie, L.6
  • 74
    • 47549100864 scopus 로고    scopus 로고
    • Treatment of type 2 diabetes and dyslipidemia with the natural plant alkaloid berberine
    • Zhang Y., Li X., Zou D., Liu W., Yang J., Zhu N., et al. Treatment of type 2 diabetes and dyslipidemia with the natural plant alkaloid berberine. J Clin Endocrinol Metab 2008, 93:2559-2565.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 2559-2565
    • Zhang, Y.1    Li, X.2    Zou, D.3    Liu, W.4    Yang, J.5    Zhu, N.6
  • 75
    • 60949108484 scopus 로고    scopus 로고
    • Protective effect of berberine on beta cells in streptozotocin- and high-carbohydrate/high-fat diet-induced diabetic rats
    • Zhou J., Zhou S., Tang J., Zhang K., Guang L., Huang Y., et al. Protective effect of berberine on beta cells in streptozotocin- and high-carbohydrate/high-fat diet-induced diabetic rats. Eur J Pharmacol 2009, 606:262-268.
    • (2009) Eur J Pharmacol , vol.606 , pp. 262-268
    • Zhou, J.1    Zhou, S.2    Tang, J.3    Zhang, K.4    Guang, L.5    Huang, Y.6
  • 76
    • 54249167953 scopus 로고    scopus 로고
    • Neuroprotective effects of berberine on stroke models in vitro and in vivo
    • Zhou X., Zeng X., Kong H., Sun X. Neuroprotective effects of berberine on stroke models in vitro and in vivo. Neurosci Lett 2008, 447:31-36.
    • (2008) Neurosci Lett , vol.447 , pp. 31-36
    • Zhou, X.1    Zeng, X.2    Kong, H.3    Sun, X.4
  • 77
    • 33845602246 scopus 로고    scopus 로고
    • Berberine chloride can ameliorate the spatial memory impairment and increase the expression of interleukin-1beta and inducible nitric oxide synthase in the rat model of Alzheimer's disease
    • Zhu F., Qian C. Berberine chloride can ameliorate the spatial memory impairment and increase the expression of interleukin-1beta and inducible nitric oxide synthase in the rat model of Alzheimer's disease. BMC Neurosci 2006, 7:78.
    • (2006) BMC Neurosci , vol.7 , pp. 78
    • Zhu, F.1    Qian, C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.