PCTAIRE kinase 3/cyclin-dependent kinase 18 is activated through association with cyclin a and/or phosphorylation by protein kinase a

Journal of Biological Chemistry

Volumn 289, Issue 26, 2014, Pages 18387-18400

  Matsuda, Shinya ^a   Kominato, Kyohei ^a   Koide Yoshida, Shizuyo ^a   Miyamoto, Kenji ^a   Isshiki, Kinuka ^a   Tsuji, Akihiko ^a   Yuasa, Keizo ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ASSAYS; CHEMICAL ACTIVATION; CYTOLOGY; PHOSPHORYLATION; PROTEINS;

AMINO ACID SEQUENCE ANALYSIS; CATALYTIC ACTIVATION; IMMUNOCYTOCHEMISTRY; PHOSPHORYLATION SITES; PHYSIOLOGICAL FUNCTIONS; PROTEIN KINASE; PROTEIN KINASE A; RETINOBLASTOMA PROTEIN;

ENZYMES;

COFILIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIN A2; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE 18; CYCLIN E; CYCLIN E1; PCTAIRE KINASE 3; RETINOBLASTOMA PROTEIN; SERINE; SERINE 109; SERINE 12; SERINE 66; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CATALYSIS; CELL METABOLISM; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME LOCALIZATION; ENZYME MECHANISM; ENZYME PHOSPHORYLATION; ENZYME SPECIFICITY; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN PROTEIN INTERACTION; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION;

COFILIN; CYCLIN; CYCLIN-DEPENDENT KINASE (CDK); CYTOSKELETON; PROTEIN KINASE A (PKA);

ANIMALS; CELL LINE; CYCLIC AMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNITS; CYCLIN A2; CYCLIN-DEPENDENT KINASES; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MICE; PHOSPHORYLATION; PROTEIN BINDING;

EID: 84903541739     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.542936     Document Type: Article

References (51)

1. Malumbres, M., and Barbacid, M. (2005) Mammalian cyclin-dependent kinases. Trends Biochem. Sci. 30, 630-641
2. Kaldis, P. (1999) The cdk-activating kinase (CAK): from yeast to mammals. Cell. Mol. Life Sci. 55, 284-296
3. Nakayama, K. I., and Nakayama, K. (2006) Ubiquitin ligases: cell-cycle control and cancer. Nat. Rev. Cancer 6, 369-381
4. Morgan, D. O. (1997) Cyclin-dependent kinases: engines, clocks, and microprocessors. Annu. Rev. Cell Dev. Biol. 13, 261-291
5. Cole A. R. (2009) PCTK proteins: the forgotten brain kinases? Neurosignals 17, 288-297
6. Graeser, R., Gannon, J., Poon, R. Y., Dubois, T., Aitken, A., and Hunt, T. (2002) Regulation of the CDK-related protein kinase PCTAIRE-1 and its possible role in neurite outgrowth in Neuro-2A cells. J. Cell Sci. 115, 3479-3490
7. Palmer, K. J., Konkel, J. E., and Stephens, D. J. (2005) PCTAIRE protein kinases interact directly with the COPII complex and modulate secretory cargo transport. J. Cell Sci. 118, 3839-3847
8. Liu, Y., Cheng, K., Gong, K., Fu, A. K., and Ip, N. Y. (2006) Pctaire1 phosphorylates N-ethylmaleimide-sensitive fusion protein: implications in the regulation of its hexamerization and exocytosis. J. Biol. Chem. 281, 9852-9858
9. Ou, C. Y., Poon, V. Y., Maeder, C. I., Watanabe, S., Lehrman, E. K., Fu, A. K., Park, M., Fu, W. Y., Jorgensen, E. M., Ip, N. Y., and Shen, K. (2010) Two cyclin-dependent kinase pathways are essential for polarized trafficking of presynaptic components. Cell 141, 846-858
10. Mikolcevic, P., Sigl, R., Rauch, V., Hess, M. W., Pfaller, K., Barisic, M., Pelliniemi, L. J., Boesl, M., and Geley, S. (2012) Cyclin-dependent kinase 16/PCTAIRE kinase 1 is activated by cyclin Y and is essential for spermatogenesis. Mol. Cell Biol. 32, 868-879
11. Hirose, T., Kawabuchi, M., Tamaru, T., Okumura, N, Nagai, K., Okada, M. (2000) Identification of tudor repeat associator with PCTAIRE 2 (Trap). A novel protein that interacts with the N-terminal domain of PCTAIRE 2 in rat brain. Eur. J. Biochem. 267, 2113-2121
12. Yamochi, T., Nishimoto, I., Okuda, T., and Matsuoka, M. (2001) ik3-1/Cables is associated with Trap and Pctaire2. Biochem. Biophys. Res. Commun. 286, 1045-1050
13. Liu, D., Matzuk, M. M., Sung, W. K., Guo, Q., Wang, P., and Wolgemuth, D. J. (1998) Cyclin A1 is required for meiosis in the male mouse. Nat. Genet. 20, 377-380
14. Tsang, W. Y., Wang, L., Chen, Z., Sänchez, I., and Dynlacht, B. D. (2007) SCAPER, a novel cyclin A: interacting protein that regulates cell cycle progression. J. Cell Biol. 178, 621-633
15. Arsic, N, Bendris, N, Peter, M., Begon-Pescia, C, Rebouissou, C, Gadéa, G., Bouquier, N, Bibeau, F., Lemmers, B., and Blanchard, J. M. (2012) A novel function for cyclin A2: control of cell invasion via RhoA signaling. J. Cell Biol. 196, 147-162
16. Pearce, L. R., Komander, D., and Alessi, D. R. (2010) The nuts and bolts of AGC protein kinases. Nat. Rev. Mol. Cell Biol. 11, 9-22
17. 2/M transition in Xenopus oocytes by the cAMP-dependent protein kinase. J. Biol. Chem. 280, 24339-24346
18. 2 cell cycle arrest: a direct link between PKA and Cdc25C. Cell Cycle 2, 39-41
19. Han, S. J., and Conti, M. (2006) New pathways from PKA to the Cdc2/cyclin B complex in oocytes: Wee1B as a potential PKA substrate. Cell Cycle 5, 227-231
20. Parker, L. L., and Piwnica-Worms, H. (1992) Inactivation of the p34cdc2-cyclin B complex by the human WEE1 tyrosine kinase. Science. 257, 1955-1957
21. Nilsson, I., and Hoffmann, I. (2000) Cell cycle regulation by the Cdc25 phosphatase family. Prog. Cell Cycle Res. 4, 107-114
22. Yuasa, K., Michibata, H, Omori, K., and Yanaka N. (1999) A novel interaction of cGMP-dependent protein kinase I with troponin T. J. Biol. Chem. 274, 37429-37434
23. Yuasa, K., Matsuda, T., and Tsuji, A. (2011) Functional regulation of transient receptor potential canonical 7 by cGMP-dependent protein kinase Ia. Cell Signal. 23, 1179-1187
24. Shehata, S. N, Hunter, R. W., Ohta, E., Peggie, M. W., Lou, H. J., Sicheri, F., Zeqiraj, E., Turk, B. E., and Sakamoto, K. (2012) Analysis of substrate specificity and cyclin Y binding of PCTAIRE-1 kinase. Cell. Signal. 24, 2085-2094
25. Rual, J. F., Venkatesan, K., Hao, T., Hirozane-Kishikawa, T., Dricot, A., Li, N., Berriz, G. F., Gibbons, F. D., Dreze, M., Ayivi-Guedehoussou, N, Klitgord, N, Simon, C, Boxem, M., Milstein, S., Rosenberg, J., Goldberg, D. S., Zhang, L. V., Wong, S. L., Franklin, G., Li, S., Albala, J. S., Lim, J., Fraughton, C, Llamosas, E., Cevik, S., Bex, C, Lamesch, P., Sikorski, R. S., Vandenhaute, J., Zoghbi, H. Y., Smolyar, A., Bosak, S., Sequerra, R., Doucette-Stamm, L., Cusick, M. E., Hill, D. E., Roth, F. P., and Vidal, M. (2005) Towards a proteome-scale map of the human protein-protein interaction network. Nature 437, 1173-1178
26. Shu, F., Lv, S., Qin, Y., Ma, X., Wang, X., Peng, X., Luo, Y., Xu, B. E., Sun, X., and Wu, J. (2007) Functional characterization of human PFTK1 as a cyclin-dependent kinase. Proc. Natl. Acad. Sci. U. S. A. 104, 9248-9253
27. Jiang, M., Gao, Y., Yang, T., Zhu, X., and Chen, J. (2009) Cyclin Y, a novel membrane-associated cyclin, interacts with PFTK1. FEBS Lett. 583, 2171-2178
28. Adams, P. D., Li, X., Sellers, W. R., Baker, K. B., Leng, X., Harper, J. W., Taya, Y., and Kaelin, W. G. Jr. (1999) Retinoblastoma protein contains a C-terminal motif that targets it for phosphorylation by cyclin-cdk complexes. Mol. Cell Biol. 19, 1068-1080
29. Meyerson, M., Enders, G. H, Wu, C. L., Su, L. K., Gorka, C, Nelson, C, Harlow, E., and Tsai, L. H. (1992) A family of human cdc2-related protein kinases. EMBOJ. 11, 2909-2917
30. Jackman, M., Kubota, Y., Den Elzen, N., Hagting, A., and Pines, J. (2002) Cyclin A- and cyclin E-Cdk complexes shuttle between the nucleus and the cytoplasm. Mol. Biol. Cell 13, 1030-1045
31. Den Elzen, N., and Pines, J. (2001) Cyclin A is destroyed in prometaphase and can delay chromosome alignment and anaphase. J. Cell Biol. 153, 121-136
32. Clurman, B. E., Sheaff, R. J., Thress, K., Groudine, M., and Roberts, J. M. (1996) Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation. Genes Dev. 10, 1979-1990
33. Moon, A., and Drubin, D. G. (1995) The ADF/cofilin proteins: stimulusresponsive modulators of actin dynamics. Mol. Biol. Cell 6, 1423-1431
34. Moriyama, K., Iida, K., and Yahara, I. (1996) Phosphorylation of Ser-3 of cofilin regulates its essential function on actin. Genes Cells 1, 73-86
35. Jeffrey, P. D., Russo, A. A., Polyak, K., Gibbs, E., Hurwitz, J., Massagué, J., and Pavletich, N. P. (1995) Mechanism of CDK activation revealed by the structure of a cyclin A-CDK2 complex. Nature 376, 313-320
36. Brown, N. R., Noble, M. E., Endicott, J. A., and Johnson, L. N. (1999) The structural basis for specificity of substrate and recruitment peptides for cyclin-dependent kinases. Nat. Cell Biol. 1, 438-443
37. Peeper, D. S., Parker, L. L., Ewen, M. E., Toebes, M., Hall, F. L., Xu, M., Zantema, A., Van Der Eb, A. J., and Piwnica-Worms, H. (1993) A- and B-type cyclins differentially modulate substrate specificity of cyclin-cdk complexes. EMBO J. 12, 1947-1954
38. Sarcevic, B., Lilischkis, R., and Sutherland, R. L. (1997) Differential phosphorylation of T-47D human breast cancer cell substrates by D1-, D3-, E-, and A-type cyclin-CDK complexes. J. Biol. Chem. 272, 33327-33337
39. Horton, L. E., and Templeton, D. J. (1997) The cyclin box and C terminus of cyclins A and E specify CDK activation and substrate specificity. Oncogene 14, 491-498
40. Odajima, J., Wills, Z. P., Ndassa, Y. M., Terunuma, M., Kretschmannova, K., Deeb, T. Z., Geng, Y., Gawrzak, S., Quadros, I. M., Newman, J., Das, M., Jecrois, M. E., Yu, Q., Li, N., Bienvenu, F., Moss, S. J., Greenberg, M. E., Marto, J. A., and Sicinski, P. (2011) Cyclin E constrains Cdk5 activity to regulate synaptic plasticity and memory formation. Dev. Cell 21, 655-668
41. Classon, M., and Harlow, E. (2002) The retinoblastoma tumour suppressor in development and cancer. Nat. Rev. Cancer 2, 910-917
42. Zacksenhaus, E., Jiang, Z., Hei, Y. J., Phillips, R. A., and Gallie, B. L. (1999) Nuclear localization conferred by the pocket domain of the retinoblastoma gene product. Biochim. Biophys. Acta 1451, 288-296
43. Maridor, G., Gallant, P., Golsteyn, R., and Nigg, E. A. (1993) Nuclear localization of vertebrate cyclin A correlates with its ability to form complexes with cdk catalytic subunits. J. Cell Sci. 106, 535-544
44. Fu, H., Subramanian, R. R., and Masters, S. C. (2000) 14-3-3 proteins: structure, function, and regulation. Annu. Rev. Pharmacol. Toxicol. 40, 617-647
45. Meek, S. E., Lane, W. S., and Piwnica-Worms, H. (2004) Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins. J. Biol. Chem. 279, 32046-32054
46. Shabb, J. B. (2001) Physiological substrates of cAMP-dependent protein kinase. Chem. Rev. 101, 2381-2411
47. Liu, F., Verin, A. D., Borbiev, T., and Garcia, J. G. (2001) Role of cAMP-dependent protein kinase A activity in endothelial cell cytoskeleton rearrangement. Am. J. Physiol. Lung Cell. Mol. Physiol. 280, L1309-L1317
48. Nadella, K. S., Saji, M., Jacob, N. K., Pavel, E., Ringel, M. D., and Kirschner, L. S. (2009) Regulation of actin function by protein kinase A-mediated phosphorylation of Limk1. EMBO Rep. 10, 599-605
49. Dhavan, R., and Tsai, L. H. (2001) A decade of CDK5. Nat. Rev. Mol. Cell Biol. 2, 749-759
50. Rashid, T., Banerjee, M., and Nikolic, M. (2001) Phosphorylation of Pak1 by the p35/Cdk5 kinase affects neuronal morphology. J. Biol. Chem. 276, 49043-49052
51. Hanna, S., and El-Sibai, M. (2013) Signaling networks of Rho GTPases in cell motility. Cell. Signal. 25, 1955-1961