Identification of licopyranocoumarin and glycyrurol from herbal medicines as neuroprotective compounds for Parkinson's disease

PLoS ONE

Volumn 9, Issue 6, 2014, Pages

  Fujimaki, Takahiro ^a   Saiki, Shinji ^b   Tashiro, Etsu ^a   Yamada, Daisuke ^b   Kitagawa, Mitsuhiro ^a   Hattori, Nobutaka ^b   Imoto, Masaya ^a  

^a KEIO UNIVERSITY   (Japan)

^b JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCYRUROL; KAEMPFEROL; LICOPYRANOCOUMARIN; PLANT MEDICINAL PRODUCT; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; ANTIOXIDANT; COUMARIN DERIVATIVE; NEUROPROTECTIVE AGENT; PHENOL DERIVATIVE; PLANT EXTRACT;

ANTIOXIDANT ACTIVITY; ARTICLE; CELL CYCLE G1 PHASE; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; CRYOPROTECTION; DOSE RESPONSE; DPPH RADICAL SCAVENGING ASSAY; DRUG EFFICACY; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG SCREENING; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVITY; GLYCYRRHIZA; IC 50; MITOCHONDRIAL MEMBRANE POTENTIAL; NERVE CELL; NEUROPROTECTION; PARKINSON DISEASE; ANIMAL; APOPTOSIS; CELL SURVIVAL; CHEMISTRY; DISEASE MODEL; DRUG EFFECTS; HERBAL MEDICINE; ISOLATION AND PURIFICATION; MEDICINAL PLANT; METABOLISM; PC12 CELL LINE; RAT;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; CELL SURVIVAL; COUMARINS; DISEASE MODELS, ANIMAL; DRUG EVALUATION, PRECLINICAL; HERBAL MEDICINE; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MEMBRANE POTENTIAL, MITOCHONDRIAL; NEUROPROTECTIVE AGENTS; PARKINSON DISEASE; PC12 CELLS; PHENOLS; PLANT EXTRACTS; PLANTS, MEDICINAL; RATS; REACTIVE OXYGEN SPECIES;

EID: 84903539435     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0100395     Document Type: Article

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