Single-step selection of bivalent aptamers validated by comparison with SELEX using high-throughput sequencing

PLoS ONE

Volumn 9, Issue 6, 2014, Pages

  Wilson, Robert ^a   Bourne, Christian ^a   Chaudhuri, Roy R ^a,b   Gregory, Richard ^a   Kenny, John ^a   Cossins, Andrew ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

APTAMER; THROMBIN;

ANALYTIC METHOD; ARTICLE; COMBINATORIAL CHEMISTRY; CONTROLLED STUDY; DNA LIBRARY; HIGH THROUGHPUT SEQUENCING; INTERMETHOD COMPARISON; NUCLEOTIDE SEQUENCE; SEQUENCE ANALYSIS; SINGLE STEP SELECTION; VALIDATION STUDY; BIOLOGY; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; DNA SEQUENCE; ENZYME ACTIVE SITE; GENETICS; HUMAN; METABOLISM; NUCLEOTIDE MOTIF; PROCEDURES; SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENT APTAMER TECHNIQUE;

APTAMERS, NUCLEOTIDE; BASE SEQUENCE; CATALYTIC DOMAIN; COMPUTATIONAL BIOLOGY; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; MODELS, MOLECULAR; NUCLEOTIDE MOTIFS; SELEX APTAMER TECHNIQUE; SEQUENCE ANALYSIS, DNA; THROMBIN;

EID: 84903532430     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0100572     Document Type: Article

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