The selection of DNA aptamers for two different epitopes of thrombin was not due to different partitioning methods

Nucleic Acid Therapeutics

Volumn 23, Issue 1, 2013, Pages 88-92

  Wilson, Robert ^a   Cossins, Andrew ^a   Nicolau, Dan V ^a   Missailidis, Sotiris ^b  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b OPEN UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

APTAMER; BETA THROMBIN; SIGMA THROMBIN; THROMBIN; UNCLASSIFIED DRUG;

ARTICLE; COMBINATORIAL CHEMISTRY; DNA SEQUENCE; DRUG BINDING SITE; HUMAN; PH; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE; WESTERN BLOTTING;

APTAMERS, NUCLEOTIDE; BASE SEQUENCE; BINDING SITES; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; PROTEIN CONFORMATION; PROTEIN ISOFORMS; SELEX APTAMER TECHNIQUE; THROMBIN;

EID: 84873683979     PISSN: 21593337     EISSN: None     Source Type: Journal    
DOI: 10.1089/nat.2012.0386     Document Type: Article

References (21)

1. BOCK, L.C., GRIFFIN, L.C., LATHAM, J.A., VERMAAS, E.H., and TOOLE, J.J. (1992). Selection of single-stranded DNA molecules that bind and inhibit human thrombin. Nature 355, 564-566
2. CHO, E.J., LEE, J.W., and ELLINGTON, A.D. (2009). Applications of aptamers as sensors. Annu. Rev. Anal. Chem. 2, 241-264
3. DICULESCU, V.C., CHIORCEA-PAQUIM, A.M., ERITJA, R., and OLIVEIRA-BRETT, A.M. (2011). Evaluation of the structure-activity relationship of thrombin binding aptamers by voltammetry and atomic force microscopy. J. Electroanal. Chem. 656, 159-166
4. FAMULOK, M., HARTIG, J.S., and MAYER, G. (2007). Functional aptamers and aptazymes in biotechnology, diagnostics, and therapy. Chem. Revs. 107, 3715-3743
5. FITTER, S., and JAMES, R. (2005). Deconvolution of a complex target using DNA aptamers. J. Biol. Chem. 280, 34193-34201
6. HOON, S., ZHOU, B., JANDA, K.D., BRENNEN, S., and SCOLNICK, J. (2011). Aptamer selection by high-throughput sequencing and informatic analysis. BioTechniques 51, 413-416
7. KRETZ, C.A., STAFFORD, A.R., FREDENBURGH, J.C., and WEITZ, J.I. (2006). HD1, a thrombin-directed aptamer, binds exosite 1 on prothrombin with high affinity and inhibits its activation by prothrombinase. J. Biol. Chem. 281, 37477-37485
8. LEE, J.A., HWANG, S., KWAK, J., PARK, A.I., LEE, S.S., and LEE, K.C. (2008). Sens. Actuators 129, 372-379
9. MACAYA, R.F., SCHULTZE, P., SMITH, F.W., ROE, J.A., and FEIGON, J. (1993). Thrombin-binding DNA aptamer forms a unimolecular quadruplex structure in solution. Proc. Natl. Acad. Sci. U. S. A. 90, 3745-3749
10. MAYER, G. (2009). The chemical biology of aptamers. Angew. Chem. Int. Ed. 48, 2672-2689
11. MIYACHI, Y., SHIMIZU, N., OGINO, C., and KONDO, A. (2010). Selection of DNA aptamers using atomic force microscopy. Nucleic Acids Res. 38, e21
12. STOLTENBURG, R., REINEMANN, C., and STREHLITZ, B. (2007). SELEX: A (r)evolutionary method to generate highaffinity nucleic acid ligands. Biomol. Eng. 24, 381-403
13. TASSET, D.M., KUBIK, M.F., and STEINER, W. (1997). Oligonucleotide inhibitors of human thrombin that bind distinct epitopes. J. Mol. Biol. 272, 688-698
14. WANG, C., HOSSAIN, M., MA, L., MA, Z., HICKMAN, J.J., and SU, M. (2010). Highly sensitive thermal detection of thrombin using aptamer-functionalized phase change nanoparticles. Biosens. Bioelectron. 26, 437-443
15. WANG, K.Y., MCCURDY, S., SHEA, R.G., SWAMINATHAN, S., and BOLTON, P.H. (1993). A DNA aptamer which binds to and inhibits thrombin exhibits a new structural motif for DNA Biochemistry 32, 1899-1904
16. WILSON, R. (2011). Preparationf of single-stranded DNA from PCR products with streptavidin magnetic beads. Nucleic Acid Ther. 21, 437-440
17. WILSON, R., CLAVERING, C., and HUTCHINSON, A. (2003). Electrochemiluminescence enzyme immunoassays for TNT and pentaerythritol tetranitrate. Anal. Chem. 75, 4244-4249
18. WILSON, R., MEHRABI, M., PRIOR, I.A., BECKETT, A., and HUTCHINSON, A. (2009). A reliable method for attaching biological molecules to layer-by-layer self-assemblies. Chem. Commun. 2487-2489
19. WILSON, R., SPILLER, D.G., PRIOR, I.A., BHATT, R., and HUTCHINSON, A. J. (2007A). Magnetic microspheres encoded with photoluminescent quantum dots for multiplexed detection. Mater. Chem. 17, 4400-4406
20. WILSON, R., SPILLER, D.G., PRIOR, I.A., VELTKAMP, K.J., and HUTCHINSON, A. (2007B). A simple method for preparing spectrally encoded magnetic beads for multiplexed detection. ACS Nano 1, 487-493
21. YANG, H., JI, J., LIU, Y., KONG, J., LIU, B. (2009). An aptamerbased biosensor for sensitive thrombin detection. Electrochem. Commun. 11, 38-40