Circulation kinetics and biodistribution of dual-labeled polymersomes with modulated surface charge in tumor-bearing mice: Comparison with stealth liposomes

Journal of Controlled Release

Volumn 155, Issue 2, 2011, Pages 282-288

  Lee, Jung Seok ^a   Ankone, Marc ^a   Pieters, Ebel ^b   Schiffelers, Raymond M ^b   Hennink, Wim E ^b   Feijen, Jan ^a  

^a UNIVERSITY OF TWENTE   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Biodegradable polymersomes; Biodistribution; Circulation kinetics; Dual labeling; Poly(ethylene glycol) b poly(D,L lactide); Surface charge

Indexed keywords

BIODISTRIBUTIONS; BLOOD CIRCULATION; CIRCULATION TIME; COLOCALIZATION; D , L-LACTIDE; DUAL LABELING; ENHANCED UPTAKE; HALF LIFETIME; IN-VIVO; MODULATED SURFACES; NEGATIVE SURFACE CHARGES; NEGATIVE ZETA POTENTIALS; PEG BRUSH; POLYMERSOMES; STEALTH LIPOSOMES; TISSUE DISTRIBUTIONS; TUMOR ACCUMULATION;

BEARINGS (STRUCTURAL); BIODEGRADABLE POLYMERS; BLOOD; CHARGED PARTICLES; DEXTRAN; ETHYLENE; GLYCOLS; LIPOSOMES; MAMMALS; PHYSIOLOGY; POLYETHYLENE GLYCOLS; POLYETHYLENES; SURFACE CHARGE; TUMORS; ZETA POTENTIAL;

PHOSPHOLIPIDS; LIPOSOMES;

DEXTRAN 70; DRUG VEHICLE; LIPOSOME; NANOCARRIER; POLY(ETHYLENE GLYCOL)POLY(DEXTRO,LEVO LACTIDE)COPOLYMER; POLYMER; THIOGLYCOLIC ACID; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; CARBON 14; DEXTRAN; MACROGOL; POLYLACTIDE; POLYMERSOME; TRITIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; CIRCULATION; COMPARATIVE STUDY; CONFERENCE PAPER; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG DELIVERY SYSTEM; FEMALE; HALF LIFE TIME; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; TISSUE DISTRIBUTION; ZETA POTENTIAL; BIOACCUMULATION; CIRCULATION TIME; COLLOID; CYTOTOXICITY; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG UPTAKE; EXPERIMENTAL MOUSE; IN VITRO STUDY; IN VIVO STUDY; LIVER; SURFACE CHARGE;

ANIMALS; BLOOD CIRCULATION; CARBON RADIOISOTOPES; CELL SURVIVAL; DEXTRANS; DRUG CARRIERS; FEMALE; HELA CELLS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; KINETICS; LIPOSOMES; LIVER; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; MODELS, MOLECULAR; PARTICLE SIZE; POLYESTERS; POLYETHYLENE GLYCOLS; SURFACE PROPERTIES; THIOGLYCOLATES; TISSUE DISTRIBUTION;

EID: 80054093915     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.07.028     Document Type: Conference Paper

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