Antibody repertoire deep sequencing reveals antigen-independent selection in maturing B cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 25, 2014, Pages

  Kaplinsky, Joseph ^a,b   Li, Anthony ^a,b   Sun, Amy ^c   Coffre, Maryaline ^c   Koralov, Sergei B ^c   Arnaout, Ramy ^a,b  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Development; Immunomics; Principal component analysis

Indexed keywords

ANTIBODY;

AMINO ACID SEQUENCE; ANIMAL CELL; ANTIGEN BINDING; ARTICLE; B LYMPHOCYTE; BONE MARROW; CELL MATURATION; CELL SELECTION; COMPLEMENTARITY DETERMINING REGION; FEMALE; GENE SEQUENCE; HEAVY CHAIN; MOUSE; NONHUMAN; PRE B LYMPHOCYTE; PRIORITY JOURNAL; SPLEEN;

DEVELOPMENT; IMMUNOMICS; PRINCIPAL COMPONENT ANALYSIS;

ANIMALS; B-LYMPHOCYTES; COMPLEMENTARITY DETERMINING REGIONS; FEMALE; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; IMMUNOGLOBULIN HEAVY CHAINS; MICE;

EID: 84903436924     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1403278111     Document Type: Article

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