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Volumn 187, Issue 4, 2011, Pages 1835-1844

Selection of individual VH genes occurs at the Pro-B to Pre-B cell transition

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE RECEPTOR; CELL DNA; BCR PROTEIN, MOUSE; BREAKPOINT CLUSTER REGION PROTEIN; DNA;

EID: 80051939065     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1100207     Document Type: Article
Times cited : (16)

References (70)
  • 1
    • 0020534965 scopus 로고
    • Somatic generation of antibody diversity
    • Tonegawa, S. 1983. Somatic generation of antibody diversity. Nature 302: 575-581.
    • (1983) Nature , vol.302 , pp. 575-581
    • Tonegawa, S.1
  • 2
    • 0019428994 scopus 로고
    • Identification and nucleotide sequence of a diversity DNA segment (D) of immunoglobulin heavy-chain genes
    • DOI 10.1038/290562a0
    • Sakano, H., Y. Kurosawa, M. Weigert, and S. Tonegawa. 1981. Identification and nucleotide sequence of a diversity DNA segment (D) of immunoglobulin heavychain genes. Nature 290: 562-565. (Pubitemid 11092364)
    • (1981) Nature , vol.290 , Issue.5807 , pp. 562-565
    • Sakano, H.1    Kurosawa, Y.2    Weigert, M.3    Tonegawa, S.4
  • 3
    • 0041689676 scopus 로고    scopus 로고
    • Predominant autoantibody production by early human B cell precursors
    • DOI 10.1126/science.1086907
    • Wardemann, H., S. Yurasov, A. Schaefer, J. W. Young, E. Meffre, and M. C. Nussenzweig. 2003. Predominant autoantibody production by early human B cell precursors. Science 301: 1374-1377. (Pubitemid 37075812)
    • (2003) Science , vol.301 , Issue.5638 , pp. 1374-1377
    • Wardemann, H.1    Yurasov, S.2    Schaefer, A.3    Young, J.W.4    Meffre, E.5    Nussenzweig, M.C.6
  • 4
    • 33748992038 scopus 로고    scopus 로고
    • Receptor editing in lymphocyte development and central tolerance
    • DOI 10.1038/nri1939, PII NRI1939
    • Nemazee, D. 2006. Receptor editing in lymphocyte development and central tolerance. Nat. Rev. Immunol. 6: 728-740. (Pubitemid 44453459)
    • (2006) Nature Reviews Immunology , vol.6 , Issue.10 , pp. 728-740
    • Nemazee, D.1
  • 5
    • 21844445331 scopus 로고    scopus 로고
    • The pre-B-cell receptor: Selector of fitting immunoglobulin heavy chains for the B-cell repertoire
    • DOI 10.1038/nri1649
    • Melchers, F. 2005. The pre-B-cell receptor: Selector of fitting immunoglobulin heavy chains for the B-cell repertoire. Nat. Rev. Immunol. 5: 578-584. (Pubitemid 40961335)
    • (2005) Nature Reviews Immunology , vol.5 , Issue.7 , pp. 578-584
    • Melchers, F.1
  • 6
    • 61349179407 scopus 로고    scopus 로고
    • Regulation of B-cell proliferation and differentiation by pre-B-cell receptor signalling
    • Herzog, S., M. Reth, and H. Jumaa. 2009. Regulation of B-cell proliferation and differentiation by pre-B-cell receptor signalling. Nat. Rev. Immunol. 9: 195-205.
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 195-205
    • Herzog, S.1    Reth, M.2    Jumaa, H.3
  • 7
    • 0025868702 scopus 로고
    • Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow
    • Hardy, R. R., C. E. Carmack, S. A. Shinton, J. D. Kemp, and K. Hayakawa. 1991. Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow. J. Exp. Med. 173: 1213-1225.
    • (1991) J. Exp. Med. , vol.173 , pp. 1213-1225
    • Hardy, R.R.1    Carmack, C.E.2    Shinton, S.A.3    Kemp, J.D.4    Hayakawa, K.5
  • 8
    • 0036776756 scopus 로고    scopus 로고
    • The pre-B cell receptor and its role in proliferation and Ig heavy chain allelic exclusion
    • DOI 10.1016/S1044-5323(02)00066-0
    • Mårtensson, I. L., A. Rolink, F. Melchers, C. Mundt, S. Licence, and T. Shimizu. 2002. The pre-B cell receptor and its role in proliferation and Ig heavy chain allelic exclusion. Semin. Immunol. 14: 335-342. (Pubitemid 35015079)
    • (2002) Seminars in Immunology , vol.14 , Issue.5 , pp. 335-342
    • Martensson, I.-L.1    Rolink, A.2    Melchers, F.3    Mundt, C.4    Licence, S.5    Shimizu, T.6
  • 9
    • 0030765923 scopus 로고    scopus 로고
    • Changes in the V(H) gene repertoire of developing precursor B lymphocytes in mouse bone marrow mediated by the pre-B cell receptor
    • DOI 10.1016/S1074-7613(00)80357-X
    • ten Boekel, E., F. Melchers, and A. G. Rolink. 1997. Changes in the V(H) gene repertoire of developing precursor B lymphocytes in mouse bone marrow mediated by the pre-B cell receptor. Immunity 7: 357-368. (Pubitemid 27446010)
    • (1997) Immunity , vol.7 , Issue.3 , pp. 357-368
    • Ten, B.E.1    Melchers, F.2    Rolink, A.G.3
  • 10
    • 0036790940 scopus 로고    scopus 로고
    • Galectin-1 is a stromal cell ligand of the pre-B cell receptor (BCR) implicated in synapse formation between pre-B and stromal cells and in pre-BCR triggering
    • Gauthier, L., B. Rossi, F. Roux, E. Termine, and C. Schiff. 2002. Galectin-1 is a stromal cell ligand of the pre-B cell receptor (BCR) implicated in synapse formation between pre-B and stromal cells and in pre-BCR triggering. Proc. Natl. Acad. Sci. USA 99: 13014-13019.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 13014-13019
    • Gauthier, L.1    Rossi, B.2    Roux, F.3    Termine, E.4    Schiff, C.5
  • 11
    • 67651102911 scopus 로고    scopus 로고
    • Impaired B-cell development at the pre-BII-cell stage in galectin-1-deficient mice due to inefficient pre-BII/stromal cell interactions
    • Espeli, M., S. J. C. Mancini, C. Breton, F. Poirier, and C. Schiff. 2009. Impaired B-cell development at the pre-BII-cell stage in galectin-1-deficient mice due to inefficient pre-BII/stromal cell interactions. Blood 113: 5878-5886.
    • (2009) Blood , vol.113 , pp. 5878-5886
    • Espeli, M.1    Mancini, S.J.C.2    Breton, C.3    Poirier, F.4    Schiff, C.5
  • 12
    • 34247354176 scopus 로고    scopus 로고
    • Structural insight into pre-B cell receptor function
    • DOI 10.1126/science.1139412
    • Bankovich, A. J., S. Raunser, Z. S. Juo, T. Walz, M. M. Davis, and K. C. Garcia. 2007. Structural insight into pre-B cell receptor function. Science 316: 291-294. (Pubitemid 46633108)
    • (2007) Science , vol.316 , Issue.5822 , pp. 291-294
    • Bankovich, A.J.1    Raunser, S.2    Juo, Z.S.3    Walz, T.4    Davis, M.M.5    Garcia, K.C.6
  • 13
    • 32544435585 scopus 로고    scopus 로고
    • Powered by pairing: The surrogate light chain amplifies immunoglobulin heavy chain signaling and pre-selects the antibody repertoire
    • DOI 10.1016/j.smim.2006.01.001, PII S1044532306000030, The Origin of Dignals Predicting Life and Development of B Cell Precursors: Inside Out or Outside In?
    • Vettermann, C., K. Herrmann, and H.-M. Jäck. 2006. Powered by pairing: The surrogate light chain amplifies immunoglobulin heavy chain signaling and preselects the antibody repertoire. Semin. Immunol. 18: 44-55. (Pubitemid 43238336)
    • (2006) Seminars in Immunology , vol.18 , Issue.1 , pp. 44-55
    • Vettermann, C.1    Herrmann, K.2    Jack, H.-M.3
  • 14
    • 77954957121 scopus 로고    scopus 로고
    • N-linked glycosylation selectively regulates autonomous precursor BCR function
    • Ubelhart, R., M. P. Bach, C. Eschbach, T. Wossning, M. Reth, and H. Jumaa. 2010. N-linked glycosylation selectively regulates autonomous precursor BCR function. Nat. Immunol. 11: 759-765.
    • (2010) Nat. Immunol. , vol.11 , pp. 759-765
    • Ubelhart, R.1    Bach, M.P.2    Eschbach, C.3    Wossning, T.4    Reth, M.5    Jumaa, H.6
  • 17
    • 57449084323 scopus 로고    scopus 로고
    • Autoreactive B cell receptors mimic autonomous pre-B cell receptor signaling and induce proliferation of early B cells
    • Köhler, F., E. Hug, C. Eschbach, S. Meixlsperger, E. Hobeika, J. Kofer, H. Wardemann, and H. Jumaa. 2008. Autoreactive B cell receptors mimic autonomous pre-B cell receptor signaling and induce proliferation of early B cells. Immunity 29: 912-921.
    • (2008) Immunity , vol.29 , pp. 912-921
    • Köhler, F.1    Hug, E.2    Eschbach, C.3    Meixlsperger, S.4    Hobeika, E.5    Kofer, J.6    Wardemann, H.7    Jumaa, H.8
  • 18
    • 0035017470 scopus 로고    scopus 로고
    • Negative selection at the pre-BCR checkpoint elicited by human mu heavy chains with unusual CDR3 regions
    • DOI 10.1016/S1074-7613(01)00131-5
    • Minegishi, Y., and M. E. Conley. 2001. Negative selection at the pre-BCR checkpoint elicited by human mu heavy chains with unusual CDR3 regions. Immunity 14: 631-641. (Pubitemid 32520873)
    • (2001) Immunity , vol.14 , Issue.5 , pp. 631-641
    • Minegishi, Y.1    Conley, M.E.2
  • 19
    • 0025758239 scopus 로고
    • H element reading frames
    • Gu, H., D. Kitamura, and K. Rajewsky. 1991. B cell development regulated by gene rearrangement: Arrest of maturation by membrane-bound D mu protein and selection of DH element reading frames. Cell 65: 47-54. (Pubitemid 121001212)
    • (1991) Cell , vol.65 , Issue.1 , pp. 47-54
    • Gu, H.1    Kitamura, D.2    Rajewsky, K.3
  • 21
    • 20444394778 scopus 로고    scopus 로고
    • Development of the expressed Ig CDR-H3 repertoire is marked by focusing of constraints in length, amino acid use, and charge that are first established in early B cell progenitors
    • Ivanov, I. I., R. L. Schelonka, Y. Zhuang, G. L. Gartland, M. Zemlin, and H. W. Schroeder Jr. 2005. Development of the expressed Ig CDR-H3 repertoire is marked by focusing of constraints in length, amino acid use, and charge that are first established in early B cell progenitors. J. Immunol. 174: 7773-7780. (Pubitemid 40806284)
    • (2005) Journal of Immunology , vol.174 , Issue.12 , pp. 7773-7780
    • Ivanov, I.I.1    Schelonka, R.L.2    Zhuang, Y.3    Gartland, G.L.4    Zemlin, M.5    Schroeder Jr., H.W.6
  • 22
    • 0142211139 scopus 로고    scopus 로고
    • Selection of Ig mu Heavy Chains by Complementarity-Determining Region 3 Length and Amino Acid Composition
    • Martin, D. A., H. Bradl, T. J. Collins, E. Roth, H. M. Jäck, and G. E. Wu. 2003. Selection of Ig mu heavy chains by complementarity-determining region 3 length and amino acid composition. J. Immunol. 171: 4663-4671. (Pubitemid 37310583)
    • (2003) Journal of Immunology , vol.171 , Issue.9 , pp. 4663-4671
    • Martin, D.A.1    Bradl, H.2    Collins, T.J.3    Roth, E.4    Jack, H.-M.5    Wu, G.E.6
  • 23
    • 0035413351 scopus 로고    scopus 로고
    • H12 transgenic mouse exhibits defects in pre-B cell development and is unable to make IgM+ B cells
    • H12 transgenic mouse exhibits defects in pre-B cell development and is unable to make IgM+ B cells. J. Immunol. 167: 1254-1262.
    • (2001) J. Immunol. , vol.167 , pp. 1254-1262
    • Wang, H.1    Ye, J.2    Arnold, L.W.3    McCray, S.K.4    Clarke, S.H.5
  • 26
    • 0031132875 scopus 로고    scopus 로고
    • H Repertoire Maturation during B Cell Development in Vitro: Differential Selection of Ig Heavy Chains by Fetal and Adult B Cell Progenitors
    • Marshall, A. J., C. J. Paige, and G. E. Wu. 1997. V(H) repertoire maturation during B cell development in vitro: Differential selection of Ig heavy chains by fetal and adult B cell progenitors. J. Immunol. 158: 4282-4291. (Pubitemid 127483929)
    • (1997) Journal of Immunology , vol.158 , Issue.9 , pp. 4282-4291
    • Marshall, A.J.1    Paige, C.J.2    Wu, G.E.3
  • 28
    • 3242890386 scopus 로고    scopus 로고
    • Many levels of control of V gene rearrangement frequency
    • DOI 10.1111/j.0105-2896.2004.00163.x
    • Feeney, A. J., P. Goebel, and C. R. Espinoza. 2004. Many levels of control of V gene rearrangement frequency. Immunol. Rev. 200: 44-56. (Pubitemid 38998192)
    • (2004) Immunological Reviews , vol.200 , pp. 44-56
    • Feeney, A.J.1    Goebel, P.2    Espinoza, C.R.3
  • 29
    • 0025808214 scopus 로고
    • H81X gene segments evidences a dependence of B cell clonal maturation on the structure of nascent H chains
    • H81X gene segments evidences a dependence of B cell clonal maturation on the structure of nascent H chains. J. Immunol. 147: 1406-1411.
    • (1991) J. Immunol. , vol.147 , pp. 1406-1411
    • Decker, D.J.1    Boyle, N.E.2    Klinman, N.R.3
  • 30
    • 0029031129 scopus 로고
    • Heavy chain V gene-specific elimination of B cells during the pre-B cell to B cell transition
    • Decker, D. J., G. H. Kline, T. A. Hayden, S. N. Zaharevitz, and N. R. Klinman. 1995. Heavy chain V gene-specific elimination of B cells during the pre-B cell to B cell transition. J. Immunol. 154: 4924-4935.
    • (1995) J. Immunol. , vol.154 , pp. 4924-4935
    • Decker, D.J.1    Kline, G.H.2    Hayden, T.A.3    Zaharevitz, S.N.4    Klinman, N.R.5
  • 31
    • 0037103232 scopus 로고    scopus 로고
    • H)81X heavy chains in adult mice with an assessment of complementarity-determining region 3 diversity and capacity to form pre-B cell receptor
    • H)81X heavy chains in adult mice with an assessment of complementarity-determining region 3 diversity and capacity to form pre-B cell receptor. J. Immunol. 169: 1970-1977.
    • (2002) J. Immunol. , vol.169 , pp. 1970-1977
    • Hayden, T.A.1    Riegert, P.2    Kline, G.H.3
  • 32
    • 7444256675 scopus 로고    scopus 로고
    • The evolutionary and structural 'logic' of antigen receptor diversity
    • DOI 10.1016/j.smim.2004.08.003, PII S1044532304000363, The Evolution of Rearranging Receptor Families
    • Davis, M. M. 2004. The evolutionary and structural 'logic' of antigen receptor diversity. Semin. Immunol. 16: 239-243. (Pubitemid 39445622)
    • (2004) Seminars in Immunology , vol.16 , Issue.4 , pp. 239-243
    • Davis, M.M.1
  • 33
    • 74049110516 scopus 로고    scopus 로고
    • Checkpoints in lymphocyte development and autoimmune disease
    • Von Boehmer, H., and F. Melchers. 2010. Checkpoints in lymphocyte development and autoimmune disease. Nat. Immunol. 11: 14-20.
    • (2010) Nat. Immunol. , vol.11 , pp. 14-20
    • Von Boehmer, H.1    Melchers, F.2
  • 36
    • 0022502863 scopus 로고
    • + B-cell lymphoma
    • Kleinfield, R., R. R. Hardy, D. Tarlinton, J. Dangl, L. A. Herzenberg, and M. Weigert. 1986. Recombination between an expressed immunoglobulin heavychain gene and a germline variable gene segment in a Ly 1+ B-cell lymphoma. Nature 322: 843-846. (Pubitemid 16055258)
    • (1986) Nature , vol.322 , Issue.6082 , pp. 843-846
    • Kleinfield, R.1    Hardy, R.R.2    Tarlinton, D.3
  • 37
    • 0022557584 scopus 로고
    • A novel V(H) to V(H)DJ(H) joining mechanism in heavy-chain-negative (null) pre-B cells results in heavy-chain production
    • Reth, M., P. Gehrmann, E. Petrac, and P. Wiese. 1986. A novel VH to VHDJH joining mechanism in heavy-chain-negative (null) pre-B cells results in heavy-chain production. Nature 322: 840-842. (Pubitemid 16055257)
    • (1986) Nature , vol.322 , Issue.6082 , pp. 840-842
    • Reth, M.1    Gehrmann, P.2    Petrac, E.3    Wiese, P.4
  • 38
    • 0029553058 scopus 로고
    • Immunoglobulin heavy chain gene replacement: A mechanism of receptor editing
    • DOI 10.1016/1074-7613(95)90064-0
    • Chen, C., Z. Nagy, E. T. Luning. Prak, and M. Weigert. 1995. Immunoglobulin heavy chain gene replacement: A mechanism of receptor editing. Immunity 3: 747-755. (Pubitemid 26091148)
    • (1995) Immunity , vol.3 , Issue.6 , pp. 747-755
    • Chen, C.1    Nagy, Z.2    Prak, E.L.3    Weigert, M.4
  • 39
    • 0001506104 scopus 로고    scopus 로고
    • Modulation of nontemplated nucleotide addition by Taq DNA polymerase: Primer modifications that facilitate genotyping
    • Brownstein, M. J., J. D. Carpten, and J. R. Smith. 1996. Modulation of nontemplated nucleotide addition by Taq DNA polymerase: Primer modifications that facilitate genotyping. Biotechniques 20: 1004-1006, 1008-1010.
    • (1996) Biotechniques , vol.20
    • Brownstein, M.J.1    Carpten, J.D.2    Smith, J.R.3
  • 41
    • 70350714115 scopus 로고    scopus 로고
    • Structural basis of the cross-reactivity of genetically related human anti-HIV-1 mAbs: Implications for design of V3-based immunogens
    • Burke, V., C. Williams, M. Sukumaran, S. S. Kim, H. Li, X. H. Wang, M. K. Gorny, S. Zolla-Pazner, and X. P. Kong. 2009. Structural basis of the cross-reactivity of genetically related human anti-HIV-1 mAbs: Implications for design of V3-based immunogens. Structure 17: 1538-1546.
    • (2009) Structure , vol.17 , pp. 1538-1546
    • Burke, V.1    Williams, C.2    Sukumaran, M.3    Kim, S.S.4    Li, H.5    Wang, X.H.6    Gorny, M.K.7    Zolla-Pazner, S.8    Kong, X.P.9
  • 42
    • 0036498602 scopus 로고    scopus 로고
    • Epitope recognition by diverse antibodies suggests conformational convergence in an antibody response
    • Nair, D. T., K. Singh, Z. Siddiqui, B. P. Nayak, K. V. Rao, and D. M. Salunke. 2002. Epitope recognition by diverse antibodies suggests conformational convergence in an antibody response. J. Immunol. 168: 2371-2382. (Pubitemid 34171840)
    • (2002) Journal of Immunology , vol.168 , Issue.5 , pp. 2371-2382
    • Nair, D.T.1    Singh, K.2    Siddiqui, Z.3    Nayak, B.P.4    Rao, K.V.S.5    Salunke, D.M.6
  • 43
    • 33646071250 scopus 로고    scopus 로고
    • Complete sequence assembly and characterization of the C57BL/6 mouse Ig heavy chain V region
    • Johnston, C. M., A. L. Wood, D. J. Bolland, and A. E. Corcoran. 2006. Complete sequence assembly and characterization of the C57BL/6 mouse Ig heavy chain V region. J. Immunol. 176: 4221-4234. (Pubitemid 44264401)
    • (2006) Journal of Immunology , vol.176 , Issue.7 , pp. 4221-4234
    • Johnston, C.M.1    Wood, A.L.2    Bolland, D.J.3    Corcoran, A.E.4
  • 44
    • 0141918821 scopus 로고    scopus 로고
    • Molecular signatures of anti-nuclear antibodies - Contribution of heavy chain framework residues
    • DOI 10.1016/S0161-5890(03)00223-2
    • Sedrak, P., K. Hsu, and C. Mohan. 2003. Molecular signatures of anti-nuclear antibodies - contribution of heavy chain framework residues. Mol. Immunol. 40: 491-499. (Pubitemid 37244025)
    • (2003) Molecular Immunology , vol.40 , Issue.8 , pp. 491-499
    • Sedrak, P.1    Hsu, K.2    Mohan, C.3
  • 45
    • 5344240282 scopus 로고    scopus 로고
    • The immunoglobulin IGHD locus in C57BL/6 mice
    • DOI 10.1007/s00251-004-0712-z
    • Ye, J. 2004. The immunoglobulin IGHD gene locus in C57BL/6 mice. Immunogenetics 56: 399-404. (Pubitemid 39349882)
    • (2004) Immunogenetics , vol.56 , Issue.6 , pp. 399-404
    • Ye, J.1
  • 46
    • 0031202813 scopus 로고    scopus 로고
    • Family-Specific Differences in Transcription Efficiency of Ig Heavy Chain Promoters
    • Buchanan, K. L., E. A. Smith, S. Dou, L. M. Corcoran, and C. F. Webb. 1997. Family-specific differences in transcription efficiency of Ig heavy chain promoters. J. Immunol. 159: 1247-1254. (Pubitemid 127484102)
    • (1997) Journal of Immunology , vol.159 , Issue.3 , pp. 1247-1254
    • Buchanan, K.L.1    Smith, E.A.2    Dou, S.3    Corcoran, L.M.4    Webb, C.F.5
  • 47
    • 33748141968 scopus 로고    scopus 로고
    • B-1 B cells: development, selection, natural autoantibody and leukemia
    • DOI 10.1016/j.coi.2006.07.010, PII S0952791506001464, Innate Lymphocytes/Transplantation/Immunogenetics
    • Hardy, R. R. 2006. B-1 B cells: Development, selection, natural autoantibody and leukemia. Curr. Opin. Immunol. 18: 547-555. (Pubitemid 44311455)
    • (2006) Current Opinion in Immunology , vol.18 , Issue.5 , pp. 547-555
    • Hardy, R.R.1
  • 48
    • 0026040197 scopus 로고
    • Natural auto- And polyreactive antibodies differing from antigen-induced antibodies in the H chain CDR3
    • Chen, C., M. P. Stenzel-Poore, and M. B. Rittenberg. 1991. Natural auto- and polyreactive antibodies differing from antigen-induced antibodies in the H chain CDR3. J. Immunol. 147: 2359-2367.
    • (1991) J. Immunol. , vol.147 , pp. 2359-2367
    • Chen, C.1    Stenzel-Poore, M.P.2    Rittenberg, M.B.3
  • 49
    • 33746503135 scopus 로고    scopus 로고
    • Role of B-1a cells in autoimmunity
    • DOI 10.1016/j.autrev.2005.10.007, PII S1568997205002077
    • Duan, B., and L. Morel. 2006. Role of B-1a cells in autoimmunity. Autoimmun. Rev. 5: 403-408. (Pubitemid 44143033)
    • (2006) Autoimmunity Reviews , vol.5 , Issue.6 , pp. 403-408
    • Duan, B.1    Morel, L.2
  • 51
    • 16344380083 scopus 로고    scopus 로고
    • Inherent specificities in natural antibodies: A key to immune defense against pathogen invasion
    • DOI 10.1007/s00281-004-0182-2
    • Baumgarth, N., J. W. Tung, and L. A. Herzenberg. 2005. Inherent specificities in natural antibodies: A key to immune defense against pathogen invasion. Springer Semin. Immunopathol. 26: 347-362. (Pubitemid 40468889)
    • (2005) Springer Seminars in Immunopathology , vol.26 , Issue.4 , pp. 347-362
    • Baumgarth, N.1    Tung, J.W.2    Herzenberg, L.A.3
  • 52
    • 0042430496 scopus 로고    scopus 로고
    • Interaction of murine precursor B cell receptor with stroma cells is controlled by the unique tail of l 5 and stroma cell-associated heparan sulfate
    • Bradl, H., J. Wittmann, D. Milius, C. Vettermann, and H.-M. Jäck. 2003. Interaction of murine precursor B cell receptor with stroma cells is controlled by the unique tail of l 5 and stroma cell-associated heparan sulfate. J. Immunol. 171: 2338-2348. (Pubitemid 37025540)
    • (2003) Journal of Immunology , vol.171 , Issue.5 , pp. 2338-2348
    • Bradl, H.1    Wittmann, J.2    Milius, D.3    Vettermann, C.4    Jack, H.-M.5
  • 53
    • 0033177903 scopus 로고    scopus 로고
    • The murine clan V(H) III related 7183, J606 and S107 and DNA4 families commonly encode for binding to a bacterial B cell superantigen
    • DOI 10.1016/S0161-5890(99)00085-1, PII S0161589099000851
    • Cary, S., M. Krishnan, T. N. Marion, and G. J. Silverman. 1999. The murine clan V(H) III related 7183, J606 and S107 and DNA4 families commonly encode for binding to a bacterial B cell superantigen. Mol. Immunol. 36: 769-776. (Pubitemid 29526919)
    • (1999) Molecular Immunology , vol.36 , Issue.11-12 , pp. 769-776
    • Cary, S.1    Krishnan, M.2    Marion, T.N.3    Silverman, G.J.4
  • 54
    • 0035696023 scopus 로고    scopus 로고
    • Editors and editing of anti-DNA receptors
    • DOI 10.1016/S1074-7613(01)00251-5
    • Li, H., Y. Jiang, E. T. Luning Prak, M. Radic, and M. Weigert. 2001. Editors and editing of anti-DNA receptors. Immunity 15: 947-957. (Pubitemid 34075375)
    • (2001) Immunity , vol.15 , Issue.6 , pp. 947-957
    • Li, H.1    Jiang, Y.2    Prak, E.L.3    Radic, M.4    Weigert, M.5
  • 58
    • 0032127299 scopus 로고    scopus 로고
    • Self-reactive B lymphocytes overexpressing Bcl-x(L) escape negative selection and are tolerized by clonal anergy and receptor editing
    • DOI 10.1016/S1074-7613(00)80586-5
    • Fang, W., B. C. Weintraub, B. Dunlap, P. Garside, K. A. Pape, M. K. Jenkins, C. C. Goodnow, D. L. Mueller, and T. W. Behrens. 1998. Self-reactive B lymphocytes overexpressing Bcl-xL escape negative selection and are tolerized by clonal anergy and receptor editing. Immunity 9: 35-45. (Pubitemid 28361293)
    • (1998) Immunity , vol.9 , Issue.1 , pp. 35-45
    • Fang, W.1    Weintraub, B.C.2    Dunlap, B.3    Garside, P.4    Pape, K.A.5    Jenkins, M.K.6    Goodnow, C.C.7    Mueller, D.L.8    Behrens, T.W.9
  • 59
    • 0028794466 scopus 로고
    • Analysis of homology-directed recombination in VDJ junctions from cytoplasmic Ig- pre-B cells of newborn mice
    • Chukwuocha, R. U., B. Nadel, and A. J. Feeney. 1995. Analysis of homology-directed recombination in VDJ junctions from cytoplasmic Ig- pre-B cells of newborn mice. J. Immunol. 154: 1246-1255.
    • (1995) J. Immunol. , vol.154 , pp. 1246-1255
    • Chukwuocha, R.U.1    Nadel, B.2    Feeney, A.J.3
  • 61
    • 0020026383 scopus 로고
    • Heterogeneity of the BALB/c IgM anti-phosphorylcholine antibody response
    • Owen, J. A., N. H. Sigal, and N. R. Klinman. 1982. Heterogeneity of the BALB/c IgM anti-phosphorylcholine antibody response. Nature 295: 347-348. (Pubitemid 12159274)
    • (1982) Nature , vol.295 , Issue.5847 , pp. 347-348
    • Owen, J.A.1    Sigal, N.H.2    Klinman, N.R.3
  • 66
    • 0037103361 scopus 로고    scopus 로고
    • Genetic analysis of autoantibodies in idiopathic thrombocytopenic purpura reveals evidence of clonal expansion and somatic mutation
    • Roark, J. H., J. B. Bussel, D. B. Cines, and D. L. Siegel. 2002. Genetic analysis of autoantibodies in idiopathic thrombocytopenic purpura reveals evidence of clonal expansion and somatic mutation. Blood 100: 1388-1398. (Pubitemid 34864296)
    • (2002) Blood , vol.100 , Issue.4 , pp. 1388-1398
    • Roark, J.H.1    Bussel, J.B.2    Cines, D.B.3    Siegel, D.L.4
  • 68
    • 0032146032 scopus 로고    scopus 로고
    • Autoreactivity of human VH domains from cDNA libraries: Analysis with a bacterial expression system
    • Lecerf, J. M., Y. Chen, P. Richalet-Sécordel, X. Wang, and B. D. Stollar. 1998. Autoreactivity of human VH domains from cDNA libraries: Analysis with a bacterial expression system. J. Immunol. 161: 1274-1283. (Pubitemid 28380554)
    • (1998) Journal of Immunology , vol.161 , Issue.3 , pp. 1274-1283
    • Lecerf, J.-M.1    Chen, Y.2    Richalet-Secordel, P.3    Wang, X.4    David, S.B.5
  • 69
    • 0024477105 scopus 로고
    • V(H) sequence of a human anti-Sm autoantibody. Evidence that autoantibodies can be unmutated copies of germline genes
    • Sanz, I., H. Dang, M. Takei, N. Talal, and J. D. Capra. 1989. VH sequence of a human anti-Sm autoantibody. Evidence that autoantibodies can be unmutated copies of germline genes. J. Immunol. 142: 883-887. (Pubitemid 19093922)
    • (1989) Journal of Immunology , vol.142 , Issue.3 , pp. 883-887
    • Sanz, I.1    Dang, H.2    Takei, M.3    Talal, N.4    Capra, J.D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.