Regulation of G6PD acetylation by SIRT2 and KAT9 modulates NADPH homeostasis and cell survival during oxidative stress

EMBO Journal

Volumn 33, Issue 12, 2014, Pages 1304-1320

  Wang, Yi Ping ^a   Zhou, Li Sha ^a   Zhao, Yu Zheng ^b   Wang, Shi Wen ^a   Chen, Lei Lei ^a   Liu, Li Xia ^c   Ling, Zhi Qiang ^d   Hu, Fu Jun ^d   Sun, Yi Ping ^a   Zhang, Jing Ye ^a   Yang, Chen ^c   Yang, Yi ^b   Xiong, Yue ^a,e   Guan, Kun Liang ^a,f   Ye, Dan ^a  

^a FUDAN UNIVERSITY   (China)

^b EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^d ZHEJIANG CANCER HOSPITAL   (China)

^e UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

acetylation; G6PD; nicotinamide adenine dinucleotide phosphate; reactive oxygen species; SIRT2

Indexed keywords

ELP 3 PROTEIN; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; KAT 9 PROTEIN; LYSINE; PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SIRTUIN 2; UNCLASSIFIED DRUG;

ACETYLATION; ANIMAL CELL; ARTICLE; CELL PROTECTION; CELL SURVIVAL; DEACETYLATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ERYTHROCYTE; HEK293 CELL LINE; HOMEOSTASIS; MOUSE; NONHUMAN; OXIDATION REDUCTION POTENTIAL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ACETYLATION; G6PD; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; REACTIVE OXYGEN SPECIES; SIRT2;

ACETYLATION; ANIMALS; CELL SURVIVAL; GENE KNOCKDOWN TECHNIQUES; GLUCOSEPHOSPHATE DEHYDROGENASE; GREEN FLUORESCENT PROTEINS; HEK293 CELLS; HISTONE ACETYLTRANSFERASES; HOMEOSTASIS; HUMANS; MICE; NADP; NERVE TISSUE PROTEINS; OXIDATIVE STRESS; RNA, SMALL INTERFERING; SIRTUIN 2;

EID: 84903317314     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1002/embj.201387224     Document Type: Article

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