Clinical mutants of human glucose 6-phosphate dehydrogenase: Impairment of NADP+ binding affects both folding and stability

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1792, Issue 8, 2009, Pages 804-809

  Wang, Xiao Tao ^a   Engel, Paul C ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

Dissociation constant; Glucose 6 phosphate dehydrogenase deficiency; Refolding; Stability; Structural NADP+

Indexed keywords

CHYMOTRYPSIN; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; RECOMBINANT ENZYME;

ARTICLE; CONTROLLED STUDY; DISSOCIATION CONSTANT; ENZYME DEFICIENCY; ENZYME DENATURATION; HUMAN; MELTING POINT; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN STABILITY; REPRODUCIBILITY; THERMOSTABILITY; WILD TYPE;

ANIMALS; CIRCULAR DICHROISM; ENZYME STABILITY; GLUCOSEPHOSPHATE DEHYDROGENASE; HUMANS; INFANT, NEWBORN; MODELS, MOLECULAR; MUTATION; NADP; PROTEIN CONFORMATION; PROTEIN FOLDING;

EID: 67651111819     PISSN: 09254439     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbadis.2009.05.003     Document Type: Article

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