메뉴 건너뛰기




Volumn 155, Issue 7, 2014, Pages 2402-2410

Advanced glycation end product 3 (AGE3) suppresses the mineralization of mouse stromal ST2 cells and human mesenchymal stem cells by increasing TGF-β expression and secretion

Author keywords

[No Author keywords available]

Indexed keywords

2 (5 CHLORO 2 FLUOROPHENYL) 4 (4 PYRIDINYLAMINO)PTERIDINE; ADVANCED GLYCATION END PRODUCT; ADVANCED GLYCATION END PRODUCT 3; OSTEOCALCIN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR RUNX2; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

EID: 84903289572     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2013-1818     Document Type: Article
Times cited : (59)

References (65)
  • 2
    • 33747097918 scopus 로고    scopus 로고
    • Trends in the incidence of type 2 diabetes mellitus from the 1970s to the 1990s: The Framingham Heart Study
    • DOI 10.1161/CIRCULATIONAHA.106.613828, PII 0000301720060627000011
    • Fox CS, Pencina MJ, Meigs JB, Vasan RS, Levitzky YS, D'Agostino RB Sr. Trends in the incidence of type 2 diabetes mellitus from the 1970s to the 1990s: the Framingham Heart Study. Circulation. 2006;113(25):2914-2918. (Pubitemid 44297232)
    • (2006) Circulation , vol.113 , Issue.25 , pp. 2914-2918
    • Fox, C.S.1    Pencina, M.J.2    Meigs, J.B.3    Vasan, R.S.4    Levitzky, Y.S.5    D'Agostino Sr., R.B.6
  • 3
    • 77956277984 scopus 로고    scopus 로고
    • Cohort profile: Research on Osteoarthritis/Osteoporosis Against Disability Study
    • Yoshimura N, Muraki S, Oka H, Kawaguchi H, Nakamura K, Akune T. Cohort profile: research on Osteoarthritis/Osteoporosis Against Disability Study. Int J Epidemiol. 2010;39(4):988-995.
    • (2010) Int J Epidemiol , vol.39 , Issue.4 , pp. 988-995
    • Yoshimura, N.1    Muraki, S.2    Oka, H.3    Kawaguchi, H.4    Nakamura, K.5    Akune, T.6
  • 4
    • 76449094613 scopus 로고    scopus 로고
    • Hip fracture incidence in Japan: Estimates of new patients in 2007 and 20-year trends
    • Orimo H, Yaegashi Y, Onoda T, Fukushima Y, Hosoi T, Sakata K. Hip fracture incidence in Japan: estimates of new patients in 2007 and 20-year trends. Arch Osteoporos. 2009;4(1-2):71-77.
    • (2009) Arch Osteoporos , vol.4 , Issue.1-2 , pp. 71-77
    • Orimo, H.1    Yaegashi, Y.2    Onoda, T.3    Fukushima, Y.4    Hosoi, T.5    Sakata, K.6
  • 5
    • 68949191022 scopus 로고    scopus 로고
    • Prevalence of knee osteoarthritis, lumbar spondylosis, and osteoporosis in Japanese men and women: The research on osteoarthritis/osteoporosis against disability study
    • Yoshimura N, Muraki S, Oka H, et al. Prevalence of knee osteoarthritis, lumbar spondylosis, and osteoporosis in Japanese men and women: the research on osteoarthritis/osteoporosis against disability study. J Bone Miner Metab. 2009;27(5):620-628.
    • (2009) J Bone Miner Metab , vol.27 , Issue.5 , pp. 620-628
    • Yoshimura, N.1    Muraki, S.2    Oka, H.3
  • 7
    • 33847629923 scopus 로고    scopus 로고
    • Discrepancies in bone mineral density and fracture risk in patients with type 1 and type 2 diabetes - A meta-analysis
    • DOI 10.1007/s00198-006-0253-4
    • Vestergaard P. Discrepancies in bone mineral density and fracture risk in patients with type 1 and type 2 diabetes-a meta-analysis. Osteoporos Int. 2007;18(4):427-444. (Pubitemid 46354916)
    • (2007) Osteoporosis International , vol.18 , Issue.4 , pp. 427-444
    • Vestergaard, P.1
  • 8
    • 65549127209 scopus 로고    scopus 로고
    • Diabetic patients have an increased risk of vertebral fractures independent of BMD or diabetic complications
    • Yamamoto M, Yamaguchi T, Yamauchi M, Kaji H, Sugimoto T. Diabetic patients have an increased risk of vertebral fractures independent of BMD or diabetic complications. J Bone Miner Res. 2009;24(4):702-709.
    • (2009) J Bone Miner Res , vol.24 , Issue.4 , pp. 702-709
    • Yamamoto, M.1    Yamaguchi, T.2    Yamauchi, M.3    Kaji, H.4    Sugimoto, T.5
  • 9
    • 0028929539 scopus 로고
    • Influence of age, sex, and insulin on osteoblast function: Osteoblast dysfunction in diabetes mellitus
    • Bouillon R, Bex M, Van Herck E, et al. Influence of age, sex, and insulin on osteoblast function: osteoblast dysfunction in diabetes mellitus. J Clin Endocrinol Metab. 1995;80(4):1194-1202.
    • (1995) J Clin Endocrinol Metab , vol.80 , Issue.4 , pp. 1194-1202
    • Bouillon, R.1    Bex, M.2    Van Herck, E.3
  • 10
    • 69549102956 scopus 로고    scopus 로고
    • Serum osteocalcin/bone-specific alkaline phosphatase ratio is a predictor for the presence of vertebral fractures in men with type 2 diabetes
    • Kanazawa I, Yamaguchi T, Yamamoto M, Yamauchi M, Yano S, Sugimoto T. Serum osteocalcin/bone-specific alkaline phosphatase ratio is a predictor for the presence of vertebral fractures in men with type 2 diabetes. Calcif Tissue Int. 2009;85(3):228-234.
    • (2009) Calcif Tissue Int , vol.85 , Issue.3 , pp. 228-234
    • Kanazawa, I.1    Yamaguchi, T.2    Yamamoto, M.3    Yamauchi, M.4    Yano, S.5    Sugimoto, T.6
  • 11
    • 0035135246 scopus 로고    scopus 로고
    • Advanced glycation end-products: A review
    • DOI 10.1007/s001250051591
    • Singh R, Barden A, Mori T, Beilin L. Advanced glycation end-products: a review. Diabetologia. 2001;44(2):129-146. (Pubitemid 32156196)
    • (2001) Diabetologia , vol.44 , Issue.2 , pp. 129-146
    • Singh, R.1    Barden, A.2    Mori, T.3    Beilin, L.4
  • 13
    • 33748645515 scopus 로고    scopus 로고
    • Role of collagen enzymatic and glycation induced cross-links as a determinant of bone quality in spontaneously diabetic WBN/Kob rats
    • DOI 10.1007/s00198-006-0155-5
    • Saito M, Fujii K, Mori Y, Marumo K. Role of collagen enzymatic and glycation induced cross-links as a determinant of bone quality in spontaneously diabetic WBN/Kob rats. Osteoporos Int. 2006;17(10):1514-1523. (Pubitemid 44387486)
    • (2006) Osteoporosis International , vol.17 , Issue.10 , pp. 1514-1523
    • Saito, M.1    Fujii, K.2    Mori, Y.3    Marumo, K.4
  • 14
    • 40849130165 scopus 로고    scopus 로고
    • Serum pentosidine levels are positively associated with the presence of vertebral fractures in postmenopausal women with type 2 diabetes
    • DOI 10.1210/jc.2007-1270
    • Yamamoto M, Yamaguchi T, Yamauchi M, Yano S, Sugimoto T. Serum pentosidine levels are positively associated with the presence of vertebral fractures in postmenopausal women with type 2 diabetes. J Clin Endocrinol Metab. 2008;93(3):1013-1019. (Pubitemid 351398587)
    • (2008) Journal of Clinical Endocrinology and Metabolism , vol.93 , Issue.3 , pp. 1013-1019
    • Yamamoto, M.1    Yamaguchi, T.2    Yamauchi, M.3    Yano, S.4    Sugimoto, T.5
  • 15
    • 67650263891 scopus 로고    scopus 로고
    • Pentosidine and increased fracture risk in older adults with type 2 diabetes
    • Schwartz AV, Garnero P, Hillier TA, et al. Pentosidine and increased fracture risk in older adults with type 2 diabetes. J Clin Endocrinol Metab. 2009;94(7):2380-2386.
    • (2009) J Clin Endocrinol Metab , vol.94 , Issue.7 , pp. 2380-2386
    • Schwartz, A.V.1    Garnero, P.2    Hillier, T.A.3
  • 16
    • 72249109142 scopus 로고    scopus 로고
    • Low serum level of the endogenous secretory receptor for advanced glycation end products (esRAGE) is a risk factor for prevalent vertebral fractures independent of bone mineral density in patients with type 2 diabetes
    • Yamamoto M, Yamaguchi T, Yamauchi M, Sugimoto T. Low serum level of the endogenous secretory receptor for advanced glycation end products (esRAGE) is a risk factor for prevalent vertebral fractures independent of bone mineral density in patients with type 2 diabetes. Diabetes Care. 2009;32(12):2263-2268.
    • (2009) Diabetes Care , vol.32 , Issue.12 , pp. 2263-2268
    • Yamamoto, M.1    Yamaguchi, T.2    Yamauchi, M.3    Sugimoto, T.4
  • 19
    • 84866009687 scopus 로고    scopus 로고
    • Advanced glycation end products (AGEs), but not high glucose, inhibit the osteoblastic differentiation of mouse stromal ST2 cells through the suppression of osterix expression, and inhibit cell growth and increasing cell apoptosis
    • Okazaki K, Yamaguchi T, Tanaka K, et al. Advanced glycation end products (AGEs), but not high glucose, inhibit the osteoblastic differentiation of mouse stromal ST2 cells through the suppression of osterix expression, and inhibit cell growth and increasing cell apoptosis. Calcif Tissue Int. 2012;91(4):286-296.
    • (2012) Calcif Tissue Int , vol.91 , Issue.4 , pp. 286-296
    • Okazaki, K.1    Yamaguchi, T.2    Tanaka, K.3
  • 20
    • 38149093423 scopus 로고    scopus 로고
    • The combination of high glucose and advanced glycation end-products (AGEs) inhibits the mineralization of osteoblastic MC3T3-E1 cells through glucose-induced increase in the receptor for AGEs
    • Ogawa N, Yamaguchi T, Yano S, Yamauchi M, Yamamoto M, Sugimoto T. The combination of high glucose and advanced glycation end-products (AGEs) inhibits the mineralization of osteoblastic MC3T3-E1 cells through glucose-induced increase in the receptor for AGEs. Horm Metab Res. 2007;39(12):871-875.
    • (2007) Horm Metab Res , vol.39 , Issue.12 , pp. 871-875
    • Ogawa, N.1    Yamaguchi, T.2    Yano, S.3    Yamauchi, M.4    Yamamoto, M.5    Sugimoto, T.6
  • 21
    • 0034644472 scopus 로고    scopus 로고
    • TGFβ signaling in growth control, cancer, and heritable disorders
    • Massagué J, Blain SW, Lo RS. TGFβ signaling in growth control, cancer, and heritable disorders. Cell. 2000;103(2):295-309.
    • (2000) Cell , vol.103 , Issue.2 , pp. 295-309
    • Massagué, J.1    Blain, S.W.2    Lo, R.S.3
  • 23
    • 0035341209 scopus 로고    scopus 로고
    • TGF-β-induced repression of CBFA1 by Smad3 decreases cbfa1 and osteocalcin expression and inhibits osteoblast differentiation
    • DOI 10.1093/emboj/20.9.2254
    • Alliston T, Choy L, Ducy P, Karsenty G, Derynck R. TGF-β-induced repression of CBFA1 by Smad3 decreases cbfa1 and osteocalcin expression and inhibits osteoblast differentiation. EMBO J. 2001;20(9):2254-2272. (Pubitemid 32410595)
    • (2001) EMBO Journal , vol.20 , Issue.9 , pp. 2254-2272
    • Alliston, T.1    Choy, L.2    Ducy, P.3    Karsenty, G.4    Derynck, R.5
  • 24
    • 23044448510 scopus 로고    scopus 로고
    • Repression of Runx2 function by TGF-β through recruitment of class II histone deacetylases by Smad3
    • DOI 10.1038/sj.emboj.7600729
    • Kang JS, Alliston T, Delston R, Derynck R. Repression of Runx2 function by TGF-β through recruitment of class II histone deacetylases by Smad3. EMBO J. 2005;24(14):2543-2555. (Pubitemid 41076311)
    • (2005) EMBO Journal , vol.24 , Issue.14 , pp. 2543-2555
    • Kang, J.S.1    Alliston, T.2    Delston, R.3    Derynck, R.4
  • 26
    • 77957228438 scopus 로고    scopus 로고
    • Tissue-specific calibration of extracellular matrix material properties by transforming growth factor-β and Runx2 in bone is required for hearing
    • Chang JL, Brauer DS, Johnson J, et al. Tissue-specific calibration of extracellular matrix material properties by transforming growth factor-β and Runx2 in bone is required for hearing. EMBO Rep. 2010;11(10):765-771.
    • (2010) EMBO Rep , vol.11 , Issue.10 , pp. 765-771
    • Chang, J.L.1    Brauer, D.S.2    Johnson, J.3
  • 27
    • 78349238109 scopus 로고    scopus 로고
    • Inhibition of TGF-β signaling by 1D11 antibody treatment increases bone mass and quality in vivo
    • Edwards JR, Nyman JS, Lwin ST, et al. Inhibition of TGF-β signaling by 1D11 antibody treatment increases bone mass and quality in vivo. J Bone Miner Res. 2010;25(11):2419-2426.
    • (2010) J Bone Miner Res , vol.25 , Issue.11 , pp. 2419-2426
    • Edwards, J.R.1    Nyman, J.S.2    Lwin, S.T.3
  • 28
    • 65349134769 scopus 로고    scopus 로고
    • Pharmacologic inhibition of the TGF-β type I receptor kinase has anabolic and anticatabolic effects on bone
    • Mohammad KS, Chen CG, Balooch G, et al. Pharmacologic inhibition of the TGF-β type I receptor kinase has anabolic and anticatabolic effects on bone. PLoS One. 2009;4(4):e5275.
    • (2009) PLoS One , vol.4 , Issue.4
    • Mohammad, K.S.1    Chen, C.G.2    Balooch, G.3
  • 31
    • 0028100437 scopus 로고
    • Renal TGF-β regulation in spontaneously diabetic NOD mice with correlations in mesangial cells
    • Pankewycz OG, Guan JX, Bolton WK, Gomez A, Benedict JF. Renal TGF-β regulation in spontaneously diabetic NOD mice with correlations in mesangial cells. Kidney Int. 1994;46(3):748-758. (Pubitemid 24272033)
    • (1994) Kidney International , vol.46 , Issue.3 , pp. 748-758
    • Pankewycz, O.G.1    Guan, J.-X.2    Bolton, W.K.3    Gomez, A.4    Benedict, J.F.5
  • 32
    • 0029924637 scopus 로고    scopus 로고
    • Neutralization of TGF-β by anti-TGF-β antibody attenuates kidney hypertrophy and the enhanced extracellular matrix gene expression in STZ-induced diabetic mice
    • Sharma K, Jin Y, Guo J, Ziyadeh FN. Neutralization of TGF-β by anti-TGF-β antibody attenuates kidney hypertrophy and the enhanced extracellular matrix gene expression in STZ-induced diabetic mice. Diabetes. 1996;45(4):522-530.
    • (1996) Diabetes , vol.45 , Issue.4 , pp. 522-530
    • Sharma, K.1    Jin, Y.2    Guo, J.3    Ziyadeh, F.N.4
  • 33
    • 0028980435 scopus 로고
    • PDGF and TGF-β mediate collagen production by mesangial cells exposed to advanced glycosylation end products
    • Throckmorton DC, Brogden AP, Min B, Rasmussen H, Kashgarian M. PDGF and TGF-β mediate collagen production by mesangial cells exposed to advanced glycosylation end products. Kidney Int. 1995;48(1):111-117.
    • (1995) Kidney Int , vol.48 , Issue.1 , pp. 111-117
    • Throckmorton, D.C.1    Brogden, A.P.2    Min, B.3    Rasmussen, H.4    Kashgarian, M.5
  • 34
    • 0031914414 scopus 로고    scopus 로고
    • Glycated albumin stimulates fibronectin gene expression in glomerular mesangial cells: Involvement of the transforming growth factor-β system
    • DOI 10.1046/j.1523-1755.1998.00815.x
    • Ziyadeh FN, Han DC, Cohen JA, Guo J, Cohen MP. Glycated albumin stimulates fibronectin gene expression in glomerular mesangial cells: involvement of the transforming growth factor-β system. Kidney Int. 1998;53(3):631-638. (Pubitemid 28124277)
    • (1998) Kidney International , vol.53 , Issue.3 , pp. 631-638
    • Ziyadeh, F.N.1    Han, D.C.2    Cohen, J.A.3    Guo, J.4    Cohen, M.P.5
  • 35
    • 77956229136 scopus 로고    scopus 로고
    • Transforming growth factor β 1 as a biomarker of diabetic peripheral neuropathy: Cross-sectional study
    • Ybarra J, Pou JM, Romeo JH, Merce J, Jurado J. Transforming growth factor β 1 as a biomarker of diabetic peripheral neuropathy: cross-sectional study. J Diabetes Complications. 2010;24(5):306-312.
    • (2010) J Diabetes Complications , vol.24 , Issue.5 , pp. 306-312
    • Ybarra, J.1    Pou, J.M.2    Romeo, J.H.3    Merce, J.4    Jurado, J.5
  • 36
    • 79959424664 scopus 로고    scopus 로고
    • Advanced glycation end-products induce basement membrane hypertrophy in endoneurial microvessels and disrupt the blood-nerve barrier by stimulating the release of TGF-β and vascular endothelial growth factor (VEGF) by pericytes
    • Shimizu F, Sano Y, Haruki H, Kanda T. Advanced glycation end-products induce basement membrane hypertrophy in endoneurial microvessels and disrupt the blood-nerve barrier by stimulating the release of TGF-β and vascular endothelial growth factor (VEGF) by pericytes. Diabetologia. 2011;54(6):1517-1526.
    • (2011) Diabetologia , vol.54 , Issue.6 , pp. 1517-1526
    • Shimizu, F.1    Sano, Y.2    Haruki, H.3    Kanda, T.4
  • 37
    • 0030963671 scopus 로고    scopus 로고
    • Growth factor alterations in advanced diabetic retinopathy: A possible role of blood retina barrier breakdown
    • Pfeiffer A, Spranger J, Meyer-Schwickerath R, Schatz H. Growth factor alterations in advanced diabetic retinopathy: a possible role of blood retina barrier breakdown. Diabetes. 1997;46(suppl 2):S26-S30. (Pubitemid 27377394)
    • (1997) Diabetes , vol.46 , Issue.SUPPL. 2
    • Pfeiffer, A.1    Spranger, J.2    Meyer-Schwickerath, R.3    Schatz, H.4
  • 38
    • 0036661750 scopus 로고    scopus 로고
    • Relationship between glycoxidation and cytokines in the vitreous of eyes with diabetic retinopathy
    • DOI 10.1016/S0021-5155(02)00508-7, PII S0021515502005087
    • Matsumoto Y, Takahashi M, Ogata M. Relationship between glycoxidation and cytokines in the vitreous of eyes with diabetic retinopathy. Jpn J Ophthalmol. 2002;46(4):406-412. (Pubitemid 35286592)
    • (2002) Japanese Journal of Ophthalmology , vol.46 , Issue.4 , pp. 406-412
    • Matsumoto, Y.1    Takahashi, M.2    Ogata, M.3
  • 39
    • 77953641485 scopus 로고    scopus 로고
    • Fasudil hydrochloride induces osteoblastic differentiation of stromal cell lines, C3H10T1/2 and ST2, via bone morphogenetic protein-2 expression
    • Kanazawa I, Yamaguchi T, Yano S, Yamauchi M, Sugimoto T. Fasudil hydrochloride induces osteoblastic differentiation of stromal cell lines, C3H10T1/2 and ST2, via bone morphogenetic protein-2 expression. Endocr J. 2010;57(5):415-421.
    • (2010) Endocr J , vol.57 , Issue.5 , pp. 415-421
    • Kanazawa, I.1    Yamaguchi, T.2    Yano, S.3    Yamauchi, M.4    Sugimoto, T.5
  • 40
    • 0035710746 scopus 로고    scopus 로고
    • -ΔΔCT method
    • DOI 10.1006/meth.2001.1262
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-ΔΔC(T)) method. Methods. 2001;25(4):402-408. (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 41
    • 1442313955 scopus 로고    scopus 로고
    • Endogenous TGF-β signaling suppresses maturation of osteoblastic mesenchymal cells
    • DOI 10.1038/sj.emboj.7600067
    • Maeda S, Hayashi M, Komiya S, Imamura T, Miyazono K. Endogenous TGF-β signaling suppresses maturation of osteoblastic mesenchymal cells. EMBO J. 2004;23(3):552-563. (Pubitemid 38282387)
    • (2004) EMBO Journal , vol.23 , Issue.3 , pp. 552-563
    • Maeda, S.1    Hayashi, M.2    Komiya, S.3    Imamura, T.4    Miyazono, K.5
  • 42
    • 78650305162 scopus 로고    scopus 로고
    • TGF-β inhibition restores terminal osteoblast differentiation to suppress myeloma growth
    • Takeuchi K, Abe M, Hiasa M, et al. TGF-β inhibition restores terminal osteoblast differentiation to suppress myeloma growth. PLoS One. 2010;5(3):e9870.
    • (2010) PLoS One , vol.5 , Issue.3
    • Takeuchi, K.1    Abe, M.2    Hiasa, M.3
  • 43
    • 33751197049 scopus 로고    scopus 로고
    • Regulation of osteoblast differentiation by transcription factors
    • Komori T. Regulation of osteoblast differentiation by transcription factors. J Cell Biochem. 2006;99(5):1233-1239.
    • (2006) J Cell Biochem , vol.99 , Issue.5 , pp. 1233-1239
    • Komori, T.1
  • 44
    • 84876855691 scopus 로고    scopus 로고
    • Advanced glycation end products-induced vascular calcification is mediated by oxidative stress: Functional roles of NAD(P)H-oxidase
    • Tada Y, Yano S, Yamaguchi T, et al. Advanced glycation end products-induced vascular calcification is mediated by oxidative stress: functional roles of NAD(P)H-oxidase. Horm Metab Res. 2013;45(4):267-272.
    • (2013) Horm Metab Res , vol.45 , Issue.4 , pp. 267-272
    • Tada, Y.1    Yano, S.2    Yamaguchi, T.3
  • 46
    • 0029020336 scopus 로고
    • Macrophage scavenger receptor mediates the endocytic uptake and degradation of advanced glycation end products of the Maillard reaction
    • Araki N, Higashi T, Mori T, et al. Macrophage scavenger receptor mediates the endocytic uptake and degradation of advanced glycation end products of the Maillard reaction. Eur J Biochem. 1995;230(2):408-415.
    • (1995) Eur J Biochem , vol.230 , Issue.2 , pp. 408-415
    • Araki, N.1    Higashi, T.2    Mori, T.3
  • 47
    • 84255163024 scopus 로고    scopus 로고
    • Receptor for AGE (RAGE): Signaling mechanisms in the pathogenesis of diabetes and its complications
    • Ramasamy R, Yan SF, Schmidt AM. Receptor for AGE (RAGE): signaling mechanisms in the pathogenesis of diabetes and its complications. Ann NY Acad Sci. 2011;1243:88-102.
    • (2011) Ann NY Acad Sci , vol.1243 , pp. 88-102
    • Ramasamy, R.1    Yan, S.F.2    Schmidt, A.M.3
  • 48
    • 0035793602 scopus 로고    scopus 로고
    • Cd36, a member of the class b scavenger receptor family, as a receptor for advanced glycation end products
    • Ohgami N, Nagai R, Ikemoto M, et al. Cd36, a member of the class b scavenger receptor family, as a receptor for advanced glycation end products. J Biol Chem. 2001;276(5):3195-3202.
    • (2001) J Biol Chem , vol.276 , Issue.5 , pp. 3195-3202
    • Ohgami, N.1    Nagai, R.2    Ikemoto, M.3
  • 49
    • 38449108551 scopus 로고    scopus 로고
    • The expression and down stream effect of lectin like-oxidized low density lipoprotein 1 (LOX-1) in hyperglycemic state
    • Rudijanto A. The expression and down stream effect of lectin like-oxidized low density lipoprotein 1 (LOX-1) in hyperglycemic state. Acta Med Indones. 2007;39(1):36-43.
    • (2007) Acta Med Indones , vol.39 , Issue.1 , pp. 36-43
    • Rudijanto, A.1
  • 51
    • 0024322576 scopus 로고
    • In vivo stimulation of bone formation by transforming growth factor-β
    • Noda M, Camilliere JJ. In vivo stimulation of bone formation by transforming growth factor-β. Endocrinology. 1989;124(6):2991-2994. (Pubitemid 19154136)
    • (1989) Endocrinology , vol.124 , Issue.6 , pp. 2991-2994
    • Noda, M.1    Camilliere, J.J.2
  • 55
    • 41649102233 scopus 로고    scopus 로고
    • Transforming growth factor-β prevents osteoblast apoptosis induced by skeletal unloading via PI3K/Akt, Bcl-2, and phospho-Bad signaling
    • DOI 10.1152/ajpendo.00791.2007
    • Dufour C, Holy X, Marie PJ. Transforming growth factor-β prevents osteoblast apoptosis induced by skeletal unloading via PI3K/Akt, Bcl-2, and phospho-Bad signaling. Am J Physiol Endocrinol Metab. 2008;294(4):E794-E801. (Pubitemid 351483605)
    • (2008) American Journal of Physiology - Endocrinology and Metabolism , vol.294 , Issue.4
    • Dufour, C.1    Holy, X.2    Marie, P.J.3
  • 56
    • 0034813396 scopus 로고    scopus 로고
    • The loss of Smad3 results in a lower rate of bone formation and osteopenia through dysregulation of osteoblast differentiation and apoptosis
    • Borton AJ, Frederick JP, Datto MB, Wang XF, Weinstein RS. The loss of Smad3 results in a lower rate of bone formation and osteopenia through dysregulation of osteoblast differentiation and apoptosis. J Bone Miner Res. 2001;16(10):1754-1764. (Pubitemid 32911480)
    • (2001) Journal of Bone and Mineral Research , vol.16 , Issue.10 , pp. 1754-1764
    • Borton, A.J.1    Frederick, J.P.2    Datto, M.B.3    Wang, X.-F.4    Weinstein, R.S.5
  • 57
    • 0028341364 scopus 로고
    • Effects of transforming growth factor β on bone nodule formation and expression of bone morphogenetic protein 2, osteocalcin, osteopontin, alkaline phosphatase, and type I collagenmRNAin long-term cultures of fetal rat calvarial osteoblasts
    • Harris SE, Bonewald LF, Harris MA, et al. Effects of transforming growth factor β on bone nodule formation and expression of bone morphogenetic protein 2, osteocalcin, osteopontin, alkaline phosphatase, and type I collagenmRNAin long-term cultures of fetal rat calvarial osteoblasts. J Bone Miner Res. 1994;9(6):855-863.
    • (1994) J Bone Miner Res , vol.9 , Issue.6 , pp. 855-863
    • Harris, S.E.1    Bonewald, L.F.2    Harris, M.A.3
  • 58
    • 0027325636 scopus 로고
    • Relation between body size and bone mineral density in elderly men and women
    • Edelstein SL, Barrett-Connor E. Relation between body size and bone mineral density in elderly men and women. Am J Epidemiol. 1993;138(3):160-169. (Pubitemid 23253933)
    • (1993) American Journal of Epidemiology , vol.138 , Issue.3 , pp. 160-169
    • Edelstein, S.L.1    Barrett-Connor, E.2
  • 59
    • 0026720354 scopus 로고
    • Bone mineral density in elderly men and women: Results from the Framingham osteoporosis study
    • Hannan MT, Felson DT, Anderson JJ. Bone mineral density in elderly men and women: results from the Framingham osteoporosis study. J Bone Miner Res. 1992;7(5):547-553.
    • (1992) J Bone Miner Res , vol.7 , Issue.5 , pp. 547-553
    • Hannan, M.T.1    Felson, D.T.2    Anderson, J.J.3
  • 60
    • 0031656453 scopus 로고    scopus 로고
    • Bone loss, physical activity, and weight change in elderly women: The dubbo osteoporosis epidemiology study
    • DOI 10.1359/jbmr.1998.13.9.1458
    • Nguyen TV, Sambrook PN, Eisman JA. Bone loss, physical activity, and weight change in elderly women: the Dubbo Osteoporosis Epidemiology Study. J Bone Miner Res. 1998;13(9):1458-1467. (Pubitemid 28418913)
    • (1998) Journal of Bone and Mineral Research , vol.13 , Issue.9 , pp. 1458-1467
    • Nguyen, T.V.1    Sambrook, P.N.2    Eisman, J.A.3
  • 61
    • 0036861322 scopus 로고    scopus 로고
    • Relationships among body mass, its components, and bone
    • DOI 10.1016/S8756-3282(02)00864-5, PII S8756328202008645
    • Reid IR. Relationshipsamongbody mass, its components, and bone. Bone. 2002;31:547-555. (Pubitemid 35449695)
    • (2002) Bone , vol.31 , Issue.5 , pp. 547-555
    • Reid, I.R.1
  • 62
    • 0034113384 scopus 로고    scopus 로고
    • Correlations between insulin sensitivity and bone mineral density in non-diabetic men
    • DOI 10.1046/j.1464-5491.2000.00234.x
    • Abrahamsen B, Rohold A, Henriksen JE, Beck-Nielsen H. Correlations between insulin sensitivity and bone mineral density in nondiabetic men. Diabet Med. 2000;17:124-129. (Pubitemid 30159047)
    • (2000) Diabetic Medicine , vol.17 , Issue.2 , pp. 124-129
    • Abrahamsen, B.1    Rohold, A.2    Henriksen, J.E.3    Beck-Nielsen, H.4
  • 63
    • 0027428907 scopus 로고
    • Circulating insulin levels are related to bone density in normal postmenopausal women
    • Reid IR, Evans MC, Cooper GJ, Ames RW, Stapleton J. Circulating insulin levels are related to bone density in normal postmenopausal women. Am J Physiol. 1993;265:E655-E659.
    • (1993) Am J Physiol , vol.265
    • Reid, I.R.1    Evans, M.C.2    Cooper, G.J.3    Ames, R.W.4    Stapleton, J.5
  • 64
    • 68549120751 scopus 로고    scopus 로고
    • Adiponectin is associated with changes in bone markers during glycemic control in type 2 diabetes mellitus
    • Kanazawa I, Yamaguchi T, Yamauchi M, et al. Adiponectin is associated with changes in bone markers during glycemic control in type 2 diabetes mellitus. J Clin Endocrinol Metab. 2009;94(8):3031-3037.
    • (2009) J Clin Endocrinol Metab , vol.94 , Issue.8 , pp. 3031-3037
    • Kanazawa, I.1    Yamaguchi, T.2    Yamauchi, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.