Glycated albumin stimulates fibronectin gene expression in glomerular mesangial cells: Involvement of the transforming growth factor-β system

Kidney International

Volumn 53, Issue 3, 1998, Pages 631-638

  Ziyadeh, Fuad N ^a   Han, Dong Cheol ^a   Cohen, Jonathan A ^a   Guo, Jia ^a   Cohen, Margo P ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b NONE   (United States)

Author keywords

Diabetes mellitus; Fibronectin; Glycated albumin; Mesangial matrix in diabetes; TGF ; Type II receptor

Indexed keywords

ALBUMIN; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ARTICLE; CELL ISOLATION; GENE EXPRESSION REGULATION; GLYCATION; MESANGIUM; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 0031914414     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.1998.00815.x     Document Type: Article

References (67)

1. THE DCCT RESEARCH GROUP: The effect of intensive treatment of diabetes on the development and progression of long-term complications of insulin dependent diabetes mellitus. N Engl J Med 329:977-986, 1993
2. BUNN HF, HANEY DM, KAMIN S, GABBAY KH, GALLOP PM: The biosynthesis of human hemoglobin A1c: Slow glycosylation in vivo. J Clin Invest 57:1652-1659, 1976
3. BUNN HF, GABBAY KH, GALLOP PM: The glycosylation of hemoglobin: Relevance to diabetes mellitus. Science 200:21-27, 1978
4. HIGGINS PJ, BUNN HF: Kinetic analysis of the nonenzymatic glycosylation of hemoglobin. J Biol Chem 256:5204-5208, 1981
5. COHEN MP: Diabetes and Protein Glycation. Clinical and Pathophysiologic Relevance. Philadelphia, JC Press, 1996
6. DAY JF, INGELBRETSEN CG, INGELBRETSEN WR, BAYNES JW, THORPE SR: Nonenzymatic glycosylation of serum proteins and hemoglobin: Response to changes in blood glucose levels in diabetic rats. Diabetes 29:524-527, 1980
7. GUTHROW CE, MORRIS MA, DAY JF, THORPE SR, BAYNES J: Enhanced nonenzymatic glucosylation of serum albumin in diabetes mellitus. Proc Natl Acad Sci USA 76:4258-4261, 1979
8. COHEN MP, HUD E: Measurement of plasma glycoalbumin levels with a monoclonal antibody based ELISA. J Immunol Meth 122:279-283, 1989
9. COHEN MP, ZIYADEH FN: Role of Amadori-modified nonenzymatically glycated serum proteins in the pathogenesis of diabetic nephropathy. J Am Soc Nephrol 7:183-190, 1996
10. STEFFES MW, BILOUS RW, SUTHERLAND DER, MAUER SM: Mesangial expansion as a central mechanism for loss of kidney function in diabetic patients. Diabetes 38:1077-1081, 1989
11. SAITO Y, KIDA H, TAKEDA SI, YOSHIMURA M, YOKOYAMA H, KOSHINO Y, HATTORI N: Mesangiolysis in diabetic glomeruli: Its role in the formation of nodular lesions. Kidney Int 34:389-396, 1988
12. STEFFES MW, BILOUS W, SUTHERLAND DET, MAUER SM: Cell and matrix components of the glomerular mesangium in type I diabetes. Diabetes 41:679-684, 1992
13. ABRASS CK, PETERSON CV, RAUGI GS: Phenotypic expression of collagen types in mesangial matrix of diabetic and nondiabetic rats. Diabetes 37:1695-1702, 1988
14. COHEN MP, ZIYADEH FN: Amadori glucose adducts modulate mesangial cell growth and collagen gene expression. Kidney Int 45:475-484, 1994
15. ZIYADEH FN, COHEN MP: Effects of glycated albumin on mesangial cells: Evidence for a role in diabetic nephropathy. Molec Cell Biochem 125:19-25, 1993
16. COHEN MP, HUD E, WU VY, ZIYADEH FN: Albumin modified by Amadori glucose adducts activates mesangial cell Type IV collagen gene transcription. Molec Cell Biochem 151:61-67, 1995
17. COHEN MP, HUD E: Production and characterization of monoclonal antibodies against human glycoalbumin. J Immunol Meth 117:121-129, 1989
18. COHEN MP, HUD E, WU VY: Amelioration of diabetic nephropathy with monoclonal antibodies against glycated albumin. Kidney Int 45:1673-1679, 1994
19. COHEN MP, SHARMA K, JIN Y, HUD E, WU VY, TOMASZEWSKI J, ZIYADEH FN: Prevention of diabetic nephropathy in dbldb mice with glycated albumin antagonists: A novel treatment strategy. J Clin Invest 95:2338-2345, 1995
20. COHEN MP, CLEMENTS RS, COHEN JA, SHEARMAN CW: Prevention of decline in renal function in the diabetic dbldb mouse. Diabetologia 39:270-274, 1996
21. MASSAGUE J: Receptors for the TGF-β family. Cell 69:1067-1070, 1992
22. SHARMA K, ZIYADEH FN: Biochemical events and cytokine interactions linking glucose metablism to the develpment of diabetic nephropathy. Semin Nephrol 17:80-92, 1997
23. SHARMA K, ZIYADEH FN: Hyperglycemia and diabetic kidney disease: The case for Transforming Growth Factor-β as a key mediator. Diabetes 44:1139-1146, 1995
24. ROCCO MC, CHEN Y, GOLDFARB FN: Elevated glucose stimulates TGF-β gene expression and bioactivity in proximal tubule. Kidney Int 41:107-114, 1992
25. WOLF G, SHARMA K, CHEN Y, ERICKSEN M, ZIYADEH FN: High glucose induced proliferation in mesangial cells is reversed by autocrine TGF-β. Kidney Int 42:647-656, 1992
26. ZIYADEH FN, SHARMA K, ERICKSEN M, WOIF G: Stimulation of collagen gene expression and protein synthesis in murine mesangial cells by high glucose is mediated by autocrine activity of transforming growth factor-β. J Clin Invest 93:536-542, 1994
27. YAMAMOTO T, NAKAMURA T, NOBLE N, ROUSLAHTI E, BORDER WA: Expression of transforming growth factor β is elevated in human and experimental diabetic nephropathy. Proc Natl Acad Sci USA 90:1814-1818, 1993
28. NAKAMURA TG, FUKUI M, EBIHARA I, OSADA S, NAGAOKA I, TOMINO Y, KOIDE H: mRNA expression of growth factors in glomeruli from diabetic rats. Diabetes 42:450-456, 1993
29. 1 enhances glomerular collagen synthesis in diabetic rats. Diabetes 42:1673-1677, 1993
30. SHARMA K, JIN Y, GUO J, ZIYADEH FN: Neutralization of TGF-β by anti-TGF-β antibody attenuates kidney hypertrophy and the enhanced extracellular matrix gene expression in STZ-induced diabetic mice. Diabetes 45:522-530, 1996
31. 1 mRNA is associated with up-regulation of glomerular tenascin and laminin gene expression in non-obese diabetic mice. J Am Soc Nephrol 5:1610-1617, 1995
32. BORDER WA, NOBLE NA: Transforming growth factor β in tissue fibrosis. N Engl J Med 331:1286-1292, 1994
33. KAGAMI S, BORDER WA, MILLER DE, NOBLE NA: Angiotensin II stimulates extracellular matrix protein synthesis through induction of transforming growth factor β expression in rat glomerular mesangial cells. J Clin Invest 93:2431-2437, 1994
34. 1 and matrix mRNAs in mesangial cells. Kidney Int 50:745-573, 1996
35. SABBATINI M, SANSONE G, UCCELLO F, GILIBERTI A, CONTE G, ANDREUCCI VE: Early glycosilation products induce glomerular hyperfiltration in rats. Kidney Int 42:875-881, 1992
36. ESPOSITO C, GERLACH H, BRENT J, STERN D, VLASSARA H: Endothelial receptor-mediated binding of glucose-modified albumin is associated with increased monolayer permeability and modulation of cell-surface coagulant properties. J Exp Med 170:1387-1407, 1989
37. KREISBERG JI, KARNOVSKY MJ: Glomerular cells in culture. Kidney Int 23:439-447, 1983
38. WOLF G, HABERSTROH U, NEILSON EG: Angiotensin II stimulates proliferation and biosynthesis of Type I collagen in cultured murine mesangial cells. Am J Pathol 140:95-107, 1992
39. HUD E, COHEN MP: Evaluation and performance characteristics of a novel ELISA using a monoclonal antibody to glycated albumin. Clin Chim Acta 185:157-164, 1989
40. ABE M, HARPEL JG, METZ DN, NUNES I, LOSKUTOFF DJ, RIFKIN DB: An assay for transforming growth factor-beta using cells transfected with a plasminogen activator-inhibitor-1 luciferase construct. Anal Biochem 216:276-284, 1994
41. ZIYADEH FN, SNIPES E, WATANABE M, ALVAREZ RS, GOLDFARB S, HAVERTY TP: High glucose induces cell hypertrophy and stimulates collagen gene expression in proximal tubule. Am J Physiol 259:F704-F714, 1990
42. MEYUHAS O, KLEIN A: The mouse ribosomal protein L7 gene. Its primary structure and functional analysis of the promoter region. J Biol Chem 265:11465-11473, 1990
43. LIN HY, WANG XF, NG-EATON E, WEINBERG RA, LODISH HF: Expression and cloning of the TGF-β Type II receptor, a functional transmembrane serine/threonine kinase. Cell 68:775-785, 1991
44. 1 gene expression in diabetic BB rat and NOD mouse. Am J Physiol 265:F1094-F1101, 1994
45. ROCCO M, NEILSON EG, HOYER JR, ZIYADEH FN: Attenuated expression of epithelial cell adhesion molecules in murine polycystic kidney disease. Am J Physiol 262:F679-F686, 1991
46. MEYERS JC: Differential expression of Type I collagen and cellular fibronectin. Kidney Int 43:45-52, 1993
47. COHEN MP, CLEMENTS RS, COHEN JA, SHEARMAN CW: Glycated albumin promotes a generalized vasculopathy in the db/db mouse. Biochem Biophys Res Comm 218:72-75, 1996
48. AYO SH, RADNIK GA, GARONI JA, GLASS WF, KREISBERG JI: High glucose causes an increase in extracellular matrix proteins in cultured mesangial cells. Am J Pathol 136:1339-1348, 1990
49. AYO SH, RADNIK GA, GLASS WF, GARONI JA, RAMPT E-R, APPLING DR, KREISBERG JI: Increased extracellular matrix and mRNA in mesangial cells grown in high glucose. Am J Physiol 260:F185-F191, 1991
50. HANEDA M, KIKKAWA R, HORIDE N, TOGAWA M, KOYA D, KAJIWARA N, OOSHIMA A, SHIGETA Y: Glucose enhances Type IV collagen production in cultured rat glomerular mesangial cells. Diabetologia 34:198-200, 1991
51. CRAVEN PA, DERUBERTIS FR: Protein kinase C is activated in glomeruli from streptozotocin rats. Possible mediation by glucose. J Clin Invest 83:1667-1675, 1989
52. AYO SH, RADNIK RA, GARONI J, TROYER DA, KREISBERG JI: High glucose increases diacylglycerol mass and activates protein kinase C in mesangial cell cultures. Am J Physiol 261:F571-F577, 1991
53. KREISBERG JI, RADNIK RA, AYO SH, GARONI J, SAIKUMAR P: High glucosed elevates c-fos and c-jun transcripts and proteins in mesangial cell cultures. Kidney Int 46:105-112, 1994
54. 1 (IV) transcriptional activity in a reporter mesangial cell line. Am J Physiol 36:F632-F638, 1994
55. CRAVEN PA, STUDER RK, FELDER J, PHILLIPS S, DERUBERTIS FR: Nitric oxide inhibition of transforming growth factor-β and collagen in mesangial cells. Diabetes 46:671-681, 1997
56. 1 Kidney Int 44:948-958, 1993
57. KIM S-J, DENHEZ F, KIM K-Y, HOLT JT, SPORN MB, ROBERTS AB: Activation of the second promoter of the transforming growth factor-β gene by transforming growth factor β1 and phorbol esters occurs through the same target sequences. J Biol Chem 264:19373-19378, 1989
58. MOGYOROSI A, HUFFMAN BB, GUO J, JIN Y, ERICKSEN M, SHARMA K, ZIYADEH FN: Elevated glucose concentration stimulates expression of the Type II TGF-β receptor in glomerular mesangial cells. (abstract) J Am Soc Nephrol 7:1875A, 1996
59. LADSON-WOFFORD S, RISER BL, CORTES P: High extracellular glucose concentrations increase receptors for transforming growth factor-β in rat mesangial cells in culture. (abstract) J Am Soc Nephrol 5:696A, 1994
60. DERUBERTIS FR, CRAVEN PA: Activation of protein kinase C in glomerular cells in diabetes. Mechanisms and potential links to the pathogenesis of diabetic glomerulopathy. Diabetes 43:1-8, 1994
61. CHEN RH, EBNER R, DERNYCK R: Inactivation of the Type II receptor reveals two receptor pathways for the diverse TGF-β activities. Science 260:1335-1338, 1993
62. LOPEZ-CASILLAS F, CHEIFITZ J, DOODY J, ANDRES L, LANE WAS, MASSAGUE J: Structure and expression of the membrane proteoglycan betaglycan, a component of the TGF-β receptor system. Cell 67:785-795, 1991
63. LOPEZ-CASILLAS F, WRANA JL, MASSAGUE J: Betaglycan presents ligand to the TGF-β signalling receptor. Cell 73:1435-1444, 1993
64. LOPEZ-CASILLAS F, PAYNE HM, ANDRES JL, MASSAGUE J: Betaglycan can act as a dual modulator of TGF-β access to signalling receptors: Mapping of ligand binding and GAG attachment sites. J Cell Biol 124:557-568, 1994
65. WU VY, COHEN MP: Identification of aortic endothelial cell binding proteins for Amadori adducts in glycated albumin. Biochem Biophys Res Comm 193:1131-1136, 1993
66. WU VY, COHEN MP: Receptors specific for Amadori-modified glycated albumin on murine endothelial cells. Biochem Biophys Res Comm 198:734-739, 1994
67. COHEN MP, WU VY: Evidence for a ligand receptor system mediating the biologic effects of glycated albumin in glomerular mesangial cells. Biochem Biophys Res Comm 207:521-528, 1995