Antiandrogen flutamide protects male mice from androgen-dependent toxicity in three models of spinal bulbar muscular atrophy

Endocrinology

Volumn 155, Issue 7, 2014, Pages 2624-2634

  Renier, Kayla J ^a   Troxell Smith, Sandra M ^a   Johansen, Jamie A ^b   Katsuno, Masahisa ^c   Adachi, Hiroaki ^c   Sobue, Gen ^c   Chua, Jason P ^d   Kim, Hong Sun ^d   Lieberman, Andrew P ^d   Breedlove, S Marc ^a   Jordan, Cynthia L ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

^b Children's Hospital of Michigan   (United States)

^c NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLUTAMIDE; POLYGLUTAMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CASTRATION; CONTROLLED STUDY; DRUG EFFECT; DRUG PELLET; KENNEDY DISEASE; LIFESPAN; MALE; MOTOR DYSFUNCTION; MOTOR PERFORMANCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SKELETAL MUSCLE; TRANSGENIC MOUSE; WILD TYPE;

ANDROGEN ANTAGONISTS; ANDROGENS; ANIMALS; BLOTTING, WESTERN; BULBO-SPINAL ATROPHY, X-LINKED; DISEASE MODELS, ANIMAL; FLUTAMIDE; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; ORCHIECTOMY; PEPTIDES; RECEPTORS, ANDROGEN; SURVIVAL ANALYSIS; TIME FACTORS; TREATMENT OUTCOME; TRINUCLEOTIDE REPEAT EXPANSION;

EID: 84903280903     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2013-1756     Document Type: Article

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