Administration of testosterone results in reversible deterioration in Kennedy's disease [1]

Journal of Neurology, Neurosurgery and Psychiatry

Volumn 79, Issue 1, 2008, Pages 106-107

  Kinirons, P ^a   Rouleau, Guy A ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ATORVASTATIN; BISPHOSPHONIC ACID DERIVATIVE; GLICLAZIDE; METFORMIN; OMEPRAZOLE; PAROXETINE; RAMIPRIL; TESTOSTERONE UNDECANOATE;

AGED; CASE REPORT; DEPRESSION; DRUG SUBSTITUTION; DRUG WITHDRAWAL; DYSARTHRIA; DYSPHAGIA; ELECTROMYOGRAPHY; FASCICULATION; GENETIC ANALYSIS; GYNECOMASTIA; HUMAN; HYPERCHOLESTEROLEMIA; HYPERTENSION; KENNEDY DISEASE; LETTER; MALE; MOTOR NEUROPATHY; MUSCLE ATROPHY; NAUSEA; NERVE CONDUCTION; NON INSULIN DEPENDENT DIABETES MELLITUS; OSTEOPOROSIS; PRIORITY JOURNAL; TESTIS ATROPHY; WALKING DIFFICULTY;

AGED; ATROPHY; AXONS; DISEASE PROGRESSION; GYNECOMASTIA; HUMANS; MALE; MUSCLE, SKELETAL; MUSCULAR ATROPHY, SPINAL; POLYMERASE CHAIN REACTION; RECEPTORS, ANDROGEN; TESTIS; TESTOSTERONE; TRINUCLEOTIDE REPEAT EXPANSION;

EID: 37749026167     PISSN: 00223050     EISSN: 1468330X     Source Type: Journal    
DOI: 10.1136/jnnp.2006.101899     Document Type: Letter

References (6)

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3. Katsuno M, Adachi H, Doyu M, et al. Leuprorelin rescues polyglutamine-dependent phenotypes in a transgenic mouse model of spinal and bulbar muscular atrophy. Nat Med 2003;9:768-73.
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5. Abou-Sleymane G, Chalmel F, Helmlinger D, et al. Polyglutamine expansion causes neurodegeneration by altering the neuronal differentiation program. Hum Mol Genet 2006;15:691-703.
6. Yamamoto A, Lucas JJ, Hen R. Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease. Cell 2000;101:57-66.