-
1
-
-
70349923347
-
Hepatitis B vaccines
-
[PMID: 19817017]
-
Hepatitis B vaccines. Wkly Epidemiol Rec 2009; 84: 405-419 [PMID: 19817017]
-
(2009)
Wkly Epidemiol Rec
, vol.84
, pp. 405-419
-
-
-
2
-
-
0037325438
-
Natural history and prognosis of hepatitis B
-
[PMID: 12616450]
-
Fattovich G. Natural history and prognosis of hepatitis B. Semin Liver Dis 2003; 23: 47-58 [PMID: 12616450]
-
(2003)
Semin Liver Dis
, vol.23
, pp. 47-58
-
-
Fattovich, G.1
-
3
-
-
59749096640
-
Hepatitis B virus infection
-
[PMID: 19217993 DOI: 10.1016/S0140-6736(09)60207-5]
-
Liaw YF, Chu CM. Hepatitis B virus infection. Lancet 2009; 373: 582-592 [PMID: 19217993 DOI: 10.1016/S0140-6736(09)60207-5]
-
(2009)
Lancet
, vol.373
, pp. 582-592
-
-
Liaw, Y.F.1
Chu, C.M.2
-
4
-
-
84871036375
-
Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: A systematic analysis for the Global Burden of Disease Study 2010
-
[PMID: 23245604 DOI: 10.1016/S0140-6736(12)61728-0]
-
Lozano R, Naghavi M, Foreman K, Lim S, Shibuya K, Aboyans V, Abraham J, Adair T, Aggarwal R, Ahn SY, Alvarado M, Anderson HR, Anderson LM, Andrews KG, Atkinson C, Baddour LM, Barker-Collo S, Bartels DH, Bell ML, Benjamin EJ, Bennett D, Bhalla K, Bikbov B, Bin Abdulhak A, Birbeck G, Blyth F, Bolliger I, Boufous S, Bucello C, Burch M, Burney P, Carapetis J, Chen H, Chou D, Chugh SS, Coffeng LE, Colan SD, Colquhoun S, Colson KE, Condon J, Connor MD, Cooper LT, Corriere M, Cortinovis M, de Vaccaro KC, Couser W, Cowie BC, Criqui MH, Cross M, Dabhadkar KC, Dahodwala N, De Leo D, Degenhardt L, Delossantos A, Denenberg J, Des Jarlais DC, Dharmaratne SD, Dorsey ER, Driscoll T, Duber H, Ebel B, Erwin PJ, Espindola P, Ezzati M, Feigin V, Flaxman AD, Forouzanfar MH, Fowkes FG, Franklin R, Fransen M, Freeman MK, Gabriel SE, Gakidou E, Gaspari F, Gillum RF, Gonzalez-Medina D, Halasa YA, Haring D, Harrison JE, Havmoeller R, Hay RJ, Hoen B, Hotez PJ, Hoy D, Jacobsen KH, James SL, Jasrasaria R, Jayaraman S, Johns N, Karthikeyan G, Kassebaum N, Keren A, Khoo JP, Knowlton LM, Kobusingye O, Koranteng A, Krishnamurthi R, Lipnick M, Lipshultz SE, Ohno SL, Mabweijano J, MacIntyre MF, Mallinger L, March L, Marks GB, Marks R, Matsumori A, Matzopoulos R, Mayosi BM, McAnulty JH, McDermott MM, McGrath J, Mensah GA, Merriman TR, Michaud C, Miller M, Miller TR, Mock C, Mocumbi AO, Mokdad AA, Moran A, Mulholland K, Nair MN, Naldi L, Narayan KM, Nasseri K, Norman P, O'Donnell M, Omer SB, Ortblad K, Osborne R, Ozgediz D, Pahari B, Pandian JD, Rivero AP, Padilla RP, Perez-Ruiz F, Perico N, Phillips D, Pierce K, Pope CA, Porrini E, Pourmalek F, Raju M, Ranganathan D, Rehm JT, Rein DB, Remuzzi G, Rivara FP, Roberts T, De León FR, Rosenfeld LC, Rushton L, Sacco RL, Salomon JA, Sampson U, Sanman E, Schwebel DC, Segui-Gomez M, Shepard DS, Singh D, Singleton J, Sliwa K, Smith E, Steer A, Taylor JA, Thomas B, Tleyjeh IM, Towbin JA, Truelsen T, Undurraga EA, Venketasubramanian N, Vijayakumar L, Vos T, Wagner GR, Wang M, Wang W, Watt K, Weinstock MA, Weintraub R, Wilkinson JD, Woolf AD, Wulf S, Yeh PH, Yip P, Zabetian A, Zheng ZJ, Lopez AD, Murray CJ, AlMazroa MA, Memish ZA. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012; 380: 2095-2128 [PMID: 23245604 DOI: 10.1016/S0140-6736(12)61728-0]
-
(2012)
Lancet
, vol.380
, pp. 2095-2128
-
-
Lozano, R.1
Naghavi, M.2
Foreman, K.3
Lim, S.4
Shibuya, K.5
Aboyans, V.6
Abraham, J.7
Adair, T.8
Aggarwal, R.9
Ahn, S.Y.10
Alvarado, M.11
Anderson, H.R.12
Anderson, L.M.13
Andrews, K.G.14
Atkinson, C.15
Baddour, L.M.16
Barker-Collo, S.17
Bartels, D.H.18
Bell, M.L.19
Benjamin, E.J.20
Bennett, D.21
Bhalla, K.22
Bikbov, B.23
Bin, A.A.24
Birbeck, G.25
Blyth, F.26
Bolliger, I.27
Boufous, S.28
Bucello, C.29
Burch, M.30
Burney, P.31
Carapetis, J.32
Chen, H.33
Chou, D.34
Chugh, S.S.35
Coffeng, L.E.36
Colan, S.D.37
Colquhoun, S.38
Colson, K.E.39
Condon, J.40
Connor, M.D.41
Cooper, L.T.42
Corriere, M.43
Cortinovis, M.44
de Vaccaro, K.C.45
Couser, W.46
Cowie, B.C.47
Criqui, M.H.48
Cross, M.49
Dabhadkar, K.C.50
Dahodwala, N.51
more..
-
5
-
-
1542316127
-
Hepatitis B virus infection-natural history and clinical consequences
-
[PMID: 15014185]
-
Ganem D, Prince AM. Hepatitis B virus infection-natural history and clinical consequences. N Engl J Med 2004; 350: 1118-1129 [PMID: 15014185]
-
(2004)
N Engl J Med
, vol.350
, pp. 1118-1129
-
-
Ganem, D.1
Prince, A.M.2
-
6
-
-
35548983363
-
Molecular virology of hepatitis B virus for clinicians
-
[PMID: 17981225]
-
Block TM, Guo H, Guo JT. Molecular virology of hepatitis B virus for clinicians. Clin Liver Dis 2007; 11: 685-706, vii [PMID: 17981225]
-
(2007)
Clin Liver Dis
, vol.11
, pp. 685-706
-
-
Block, T.M.1
Guo, H.2
Guo, J.T.3
-
7
-
-
77957346775
-
Molecular genetics of HBV infection
-
[PMID: 21041899 DOI: 10.3851/IMP1619]
-
Locarnini S, Zoulim F. Molecular genetics of HBV infection. Antivir Ther 2010; 15 Suppl 3: 3-14 [PMID: 21041899 DOI: 10.3851/IMP1619]
-
(2010)
Antivir Ther
, vol.15
, Issue.SUPPL. 3
, pp. 3-14
-
-
Locarnini, S.1
Zoulim, F.2
-
8
-
-
77954649544
-
Hepatitis B virology for clinicians
-
[PMID: 20638021 DOI: 10.1016/ j.cld.2010.05.001]
-
Doo EC, Ghany MG. Hepatitis B virology for clinicians. Clin Liver Dis 2010; 14: 397-408 [PMID: 20638021 DOI: 10.1016/ j.cld.2010.05.001]
-
(2010)
Clin Liver Dis
, vol.14
, pp. 397-408
-
-
Doo, E.C.1
Ghany, M.G.2
-
9
-
-
13744257618
-
Efficient inhibition of hepatitis B virus infection by acylated peptides derived from the large viral surface protein
-
[PMID: 15650187]
-
Gripon P, Cannie I, Urban S. Efficient inhibition of hepatitis B virus infection by acylated peptides derived from the large viral surface protein. J Virol 2005; 79: 1613-1622 [PMID: 15650187]
-
(2005)
J Virol
, vol.79
, pp. 1613-1622
-
-
Gripon, P.1
Cannie, I.2
Urban, S.3
-
10
-
-
84879327902
-
Sodium taurocholate cotransporting polypeptide is a functional receptor for human hepatitis B and D virus
-
[PMID: 23150796 DOI: 10.7554/eLife.00049]
-
Yan H, Zhong G, Xu G, He W, Jing Z, Gao Z, Huang Y, Qi Y, Peng B, Wang H, Fu L, Song M, Chen P, Gao W, Ren B, Sun Y, Cai T, Feng X, Sui J, Li W. Sodium taurocholate cotransporting polypeptide is a functional receptor for human hepatitis B and D virus. Elife 2012; 1: e00049 [PMID: 23150796 DOI: 10.7554/eLife.00049]
-
(2012)
Elife
, vol.1
-
-
Yan, H.1
Zhong, G.2
Xu, G.3
He, W.4
Jing, Z.5
Gao, Z.6
Huang, Y.7
Qi, Y.8
Peng, B.9
Wang, H.10
Fu, L.11
Song, M.12
Chen, P.13
Gao, W.14
Ren, B.15
Sun, Y.16
Cai, T.17
Feng, X.18
Sui, J.19
Li, W.20
more..
-
11
-
-
33846540847
-
Recent advances in hepatitis B virus research: A German point of view
-
[PMID: 17206750]
-
Glebe D. Recent advances in hepatitis B virus research: a German point of view. World J Gastroenterol 2007; 13: 8-13 [PMID: 17206750]
-
(2007)
World J Gastroenterol
, vol.13
, pp. 8-13
-
-
Glebe, D.1
-
12
-
-
33846467193
-
Intracellular transport of hepatitis B virus
-
[PMID: 17206753]
-
Kann M, Schmitz A, Rabe B. Intracellular transport of hepatitis B virus. World J Gastroenterol 2007; 13: 39-47 [PMID: 17206753]
-
(2007)
World J Gastroenterol
, vol.13
, pp. 39-47
-
-
Kann, M.1
Schmitz, A.2
Rabe, B.3
-
13
-
-
84875406231
-
Mechanism for CCC DNA synthesis in hepadnaviruses
-
[PMID: 19956651 DOI: 10.1371/journal.pone.0008093]
-
Sohn JA, Litwin S, Seeger C. Mechanism for CCC DNA synthesis in hepadnaviruses. PLoS One 2009; 4: e8093 [PMID: 19956651 DOI: 10.1371/journal.pone.0008093]
-
(2009)
PLoS One
, vol.4
-
-
Sohn, J.A.1
Litwin, S.2
Seeger, C.3
-
14
-
-
34547755447
-
Hepadnaviridae
-
In: Knipe DM, Roizman B, Howley PM, editors, 5th ed. Philadelphia: Lippincott-Raven Publishers
-
Seeger C, Zoulim F, Mason WS. Hepadnaviridae. In: Knipe DM, Roizman B, Howley PM, editors. Fields virology. 5th ed. Philadelphia: Lippincott-Raven Publishers, 2007
-
(2007)
Fields Virology
-
-
Seeger, C.1
Zoulim, F.2
Mason, W.S.3
-
15
-
-
0034057803
-
Hepatitis B virus biology
-
[PMID: 10704474]
-
Seeger C, Mason WS. Hepatitis B virus biology. Microbiol Mol Biol Rev 2000; 64: 51-68 [PMID: 10704474]
-
(2000)
Microbiol Mol Biol Rev
, vol.64
, pp. 51-68
-
-
Seeger, C.1
Mason, W.S.2
-
16
-
-
0027167557
-
An RNA stem-loop structure directs hepatitis B virus genomic RNA encapsidation
-
[PMID: 7684464]
-
Pollack JR, Ganem D. An RNA stem-loop structure directs hepatitis B virus genomic RNA encapsidation. J Virol 1993; 67: 3254-3263 [PMID: 7684464]
-
(1993)
J Virol
, vol.67
, pp. 3254-3263
-
-
Pollack, J.R.1
Ganem, D.2
-
17
-
-
0019812996
-
Electron microscopic studies of Dane particles in hepatocytes with special reference to intracellular development of Dane particles and their relation with HBeAg in serum
-
[PMID: 7308984]
-
Kamimura T, Yoshikawa A, Ichida F, Sasaki H. Electron microscopic studies of Dane particles in hepatocytes with special reference to intracellular development of Dane particles and their relation with HBeAg in serum. Hepatology 1981; 1: 392-397 [PMID: 7308984]
-
(1981)
Hepatology
, vol.1
, pp. 392-397
-
-
Kamimura, T.1
Yoshikawa, A.2
Ichida, F.3
Sasaki, H.4
-
18
-
-
0025269349
-
Immunocytochemical and electron microscopic study of hepatitis B virus antigen and complete particle production in hepatitis B virus DNA transfected HepG2 cells
-
[PMID: 2407629]
-
Roingeard P, Lu SL, Sureau C, Freschlin M, Arbeille B, Essex M, Romet-Lemonne JL. Immunocytochemical and electron microscopic study of hepatitis B virus antigen and complete particle production in hepatitis B virus DNA transfected HepG2 cells. Hepatology 1990; 11: 277-285 [PMID: 2407629]
-
(1990)
Hepatology
, vol.11
, pp. 277-285
-
-
Roingeard, P.1
Lu, S.L.2
Sureau, C.3
Freschlin, M.4
Arbeille, B.5
Essex, M.6
Romet-Lemonne, J.L.7
-
19
-
-
0023028191
-
Formation of the pool of covalently closed circular viral DNA in hepadnavirus infected cells
-
[PMID: 3768961]
-
Tuttleman JS, Pourcel C, Summers J. Formation of the pool of covalently closed circular viral DNA in hepadnavirus infected cells. Cell 1986; 47: 451-460 [PMID: 3768961]
-
(1986)
Cell
, vol.47
, pp. 451-460
-
-
Tuttleman, J.S.1
Pourcel, C.2
Summers, J.3
-
20
-
-
77957353047
-
The host-pathogen interaction during HBV infection: Immunological controversies
-
[PMID: 21041900 DOI: 10.3851/IMP1620]
-
Bertoletti A, Maini MK, Ferrari C. The host-pathogen interaction during HBV infection: immunological controversies. Antivir Ther 2010; 15 Suppl 3: 15-24 [PMID: 21041900 DOI: 10.3851/IMP1620]
-
(2010)
Antivir Ther
, vol.15
, Issue.SUPPL. 3
, pp. 15-24
-
-
Bertoletti, A.1
Maini, M.K.2
Ferrari, C.3
-
21
-
-
84862664371
-
EASL clinical practice guidelines: Management of chronic hepatitis B virus infection
-
European Association For The Study Of The Liver, [PMID: 22436845 DOI: 10.1016/j.jhep.2012.02.010]
-
European Association For The Study Of The Liver. EASL clinical practice guidelines: Management of chronic hepatitis B virus infection. J Hepatol 2012; 57: 167-185 [PMID: 22436845 DOI: 10.1016/j.jhep.2012.02.010]
-
(2012)
J Hepatol
, vol.57
, pp. 167-185
-
-
-
22
-
-
70349240414
-
Chronic hepatitis B: Update 2009
-
[PMID: 19714720 DOI: 10.1002/ hep.23190]
-
Lok AS, McMahon BJ. Chronic hepatitis B: update 2009. Hepatology 2009; 50: 661-662 [PMID: 19714720 DOI: 10.1002/ hep.23190]
-
(2009)
Hepatology
, vol.50
, pp. 661-662
-
-
Lok, A.S.1
McMahon, B.J.2
-
23
-
-
33646585175
-
A 12-week clevudine therapy showed potent and durable antiviral activity in HBeAg-positive chronic hepatitis B
-
[PMID: 16628625]
-
Lee HS, Chung YH, Lee K, Byun KS, Paik SW, Han JY, Yoo K, Yoo HW, Lee JH, Yoo BC. A 12-week clevudine therapy showed potent and durable antiviral activity in HBeAg-positive chronic hepatitis B. Hepatology 2006; 43: 982-988 [PMID: 16628625]
-
(2006)
Hepatology
, vol.43
, pp. 982-988
-
-
Lee, H.S.1
Chung, Y.H.2
Lee, K.3
Byun, K.S.4
Paik, S.W.5
Han, J.Y.6
Yoo, K.7
Yoo, H.W.8
Lee, J.H.9
Yoo, B.C.10
-
24
-
-
68549097944
-
Clinical and virological responses to clevudine therapy in chronic hepatitis B patients: Results at 1 year of an open labelled prospective study
-
[PMID: 19578244]
-
Ko SY, Kwon SY, Choe WH, Kim BK, Kim KH, Lee CH. Clinical and virological responses to clevudine therapy in chronic hepatitis B patients: results at 1 year of an open labelled prospective study. Antivir Ther 2009; 14: 585-590 [PMID: 19578244]
-
(2009)
Antivir Ther
, vol.14
, pp. 585-590
-
-
Ko, S.Y.1
Kwon, S.Y.2
Choe, W.H.3
Kim, B.K.4
Kim, K.H.5
Lee, C.H.6
-
25
-
-
77950821986
-
Identification and characterization of clevudine-resistant mutants of hepatitis B virus isolated from chronic hepatitis B patients
-
[PMID: 20164224 DOI: 10.1128/ JVI.02066-09]
-
Kwon SY, Park YK, Ahn SH, Cho ES, Choe WH, Lee CH, Kim BK, Ko SY, Choi HS, Park ES, Shin GC, Kim KH. Identification and characterization of clevudine-resistant mutants of hepatitis B virus isolated from chronic hepatitis B patients. J Virol 2010; 84: 4494-4503 [PMID: 20164224 DOI: 10.1128/ JVI.02066-09]
-
(2010)
J Virol
, vol.84
, pp. 4494-4503
-
-
Kwon, S.Y.1
Park, Y.K.2
Ahn, S.H.3
Cho, E.S.4
Choe, W.H.5
Lee, C.H.6
Kim, B.K.7
Ko, S.Y.8
Choi, H.S.9
Park, E.S.10
Shin, G.C.11
Kim, K.H.12
-
26
-
-
79959515292
-
Forty-eight weeks treatment with clevudine 30 mg qd versus lamivudine 100 mg qd for chronic hepatitis B infection: A double-blind randomized study
-
[PMID: 20924215 DOI: 10.3350/kjhep.2010.16.3.315]
-
Lau GK, Leung N. Forty-eight weeks treatment with clevudine 30 mg qd versus lamivudine 100 mg qd for chronic hepatitis B infection: a double-blind randomized study. Korean J Hepatol 2010; 16: 315-320 [PMID: 20924215 DOI: 10.3350/kjhep.2010.16.3.315]
-
(2010)
Korean J Hepatol
, vol.16
, pp. 315-320
-
-
Lau, G.K.1
Leung, N.2
-
27
-
-
79956272051
-
A comparison of 48-week treatment efficacy between clevudine and entecavir in treatment-naïve patients with chronic hepatitis B
-
[PMID: 21484144 DOI: 10.1007/s12072-010-9238-7]
-
Shin SR, Yoo BC, Choi MS, Lee DH, Song SM, Lee JH, Koh KC, Paik SW. A comparison of 48-week treatment efficacy between clevudine and entecavir in treatment-naïve patients with chronic hepatitis B. Hepatol Int 2011; 5: 664-670 [PMID: 21484144 DOI: 10.1007/s12072-010-9238-7]
-
(2011)
Hepatol Int
, vol.5
, pp. 664-670
-
-
Shin, S.R.1
Yoo, B.C.2
Choi, M.S.3
Lee, D.H.4
Song, S.M.5
Lee, J.H.6
Koh, K.C.7
Paik, S.W.8
-
28
-
-
80054123467
-
Comparison of clevudine and entecavir for treatment-naive patients with chronic hepatitis B virus infection: Two-year follow-up data
-
[PMID: 21617542 DOI: 10.1097/MCG.0b013e31821f8bdf]
-
Yoon EL, Yim HJ, Lee HJ, Lee YS, Kim JH, Jung ES, Kim JH, Seo YS, Yeon JE, Lee HS, Um SH, Byun KS. Comparison of clevudine and entecavir for treatment-naive patients with chronic hepatitis B virus infection: two-year follow-up data. J Clin Gastroenterol 2011; 45: 893-899 [PMID: 21617542 DOI: 10.1097/MCG.0b013e31821f8bdf]
-
(2011)
J Clin Gastroenterol
, vol.45
, pp. 893-899
-
-
Yoon, E.L.1
Yim, H.J.2
Lee, H.J.3
Lee, Y.S.4
Kim, J.H.5
Jung, E.S.6
Kim, J.H.7
Seo, Y.S.8
Yeon, J.E.9
Lee, H.S.10
Um, S.H.11
Byun, K.S.12
-
29
-
-
68649086002
-
Long-term therapy with clevudine for chronic hepatitis B can be associated with myopathy characterized by depletion of mitochondrial DNA
-
[PMID: 19333909 DOI: 10.1002/hep.22959]
-
Seok JI, Lee DK, Lee CH, Park MS, Kim SY, Kim HS, Jo HY, Lee CH, Kim DS. Long-term therapy with clevudine for chronic hepatitis B can be associated with myopathy characterized by depletion of mitochondrial DNA. Hepatology 2009; 49: 2080-2086 [PMID: 19333909 DOI: 10.1002/hep.22959]
-
(2009)
Hepatology
, vol.49
, pp. 2080-2086
-
-
Seok, J.I.1
Lee, D.K.2
Lee, C.H.3
Park, M.S.4
Kim, S.Y.5
Kim, H.S.6
Jo, H.Y.7
Lee, C.H.8
Kim, D.S.9
-
30
-
-
69949106858
-
Mitochondrial myopathy caused by clevudine therapy in chronic hepatitis B patients
-
[PMID: 19712273 DOI: 10.1111/j.1872034X.2009.00515.x]
-
Tak WY, Park SY, Jung MK, Jeon SW, Cho CM, Kweon YO, Kim SK, Choi YH. Mitochondrial myopathy caused by clevudine therapy in chronic hepatitis B patients. Hepatol Res 2009; 39: 944-947 [PMID: 19712273 DOI: 10.1111/j.1872034X.2009.00515.x]
-
(2009)
Hepatol Res
, vol.39
, pp. 944-947
-
-
Tak, W.Y.1
Park, S.Y.2
Jung, M.K.3
Jeon, S.W.4
Cho, C.M.5
Kweon, Y.O.6
Kim, S.K.7
Choi, Y.H.8
-
31
-
-
69949133388
-
Clevudine myopathy in patients with chronic hepatitis B
-
[PMID: 19615776 DOI: 10.1016/j.jhep.2009.04.019]
-
Kim BK, Oh J, Kwon SY, Choe WH, Ko SY, Rhee KH, Seo TH, Lim SD, Lee CH. Clevudine myopathy in patients with chronic hepatitis B. J Hepatol 2009; 51: 829-834 [PMID: 19615776 DOI: 10.1016/j.jhep.2009.04.019]
-
(2009)
J Hepatol
, vol.51
, pp. 829-834
-
-
Kim, B.K.1
Oh, J.2
Kwon, S.Y.3
Choe, W.H.4
Ko, S.Y.5
Rhee, K.H.6
Seo, T.H.7
Lim, S.D.8
Lee, C.H.9
-
32
-
-
26644440388
-
Pharmacokinetic evaluation of the hepatitis B nucleoside analogue MIV-210 in human volunteers, abstr 150
-
Harmenberg J, Larsson T, Böttiger D, Augustsson E, Mardh G, Öberg B. Pharmacokinetic evaluation of the hepatitis B nucleoside analogue MIV-210 in human volunteers, abstr 150. Antivir Res 2002; 53: 3
-
(2002)
Antivir Res
, vol.53
, pp. 3
-
-
Harmenberg, J.1
Larsson, T.2
Böttiger, D.3
Augustsson, E.4
Mardh, G.5
Öberg, B.6
-
33
-
-
33644642052
-
In vitro characterization of the anti-hepatitis B virus activity and cross-resistance profile of 2',3'-dideoxy-3'-fluoroguanosine
-
[PMID: 16495257]
-
Jacquard AC, Brunelle MN, Pichoud C, Durantel D, Carrouée-Durantel S, Trepo C, Zoulim F. In vitro characterization of the anti-hepatitis B virus activity and cross-resistance profile of 2',3'-dideoxy-3'-fluoroguanosine. Antimicrob Agents Chemother 2006; 50: 955-961 [PMID: 16495257]
-
(2006)
Antimicrob Agents Chemother
, vol.50
, pp. 955-961
-
-
Jacquard, A.C.1
Brunelle, M.N.2
Pichoud, C.3
Durantel, D.4
Carrouée-Durantel, S.5
Trepo, C.6
Zoulim, F.7
-
34
-
-
70349146239
-
Profound antiviral effect of oral administration of MIV-210 on chronic hepadnaviral infection in a woodchuck model of hepatitis B
-
[PMID: 19564357 DOI: 10.1128/ AAC.00263-09]
-
Michalak TI, Zhang H, Churchill ND, Larsson T, Johansson NG, Oberg B. Profound antiviral effect of oral administration of MIV-210 on chronic hepadnaviral infection in a woodchuck model of hepatitis B. Antimicrob Agents Chemother 2009; 53: 3803-3814 [PMID: 19564357 DOI: 10.1128/ AAC.00263-09]
-
(2009)
Antimicrob Agents Chemother
, vol.53
, pp. 3803-3814
-
-
Michalak, T.I.1
Zhang, H.2
Churchill, N.D.3
Larsson, T.4
Johansson, N.G.5
Oberg, B.6
-
35
-
-
52949101763
-
LB80380: A promising new drug for the treatment of chronic hepatitis B
-
[PMID: 18808318 DOI: 10.1517/13 543784.17.10.1581]
-
Fung J, Lai CL, Yuen MF. LB80380: a promising new drug for the treatment of chronic hepatitis B. Expert Opin Investig Drugs 2008; 17: 1581-1588 [PMID: 18808318 DOI: 10.1517/13 543784.17.10.1581]
-
(2008)
Expert Opin Investig Drugs
, vol.17
, pp. 1581-1588
-
-
Fung, J.1
Lai, C.L.2
Yuen, M.F.3
-
36
-
-
33845675035
-
A randomized placebo controlled, dose-finding study of oral LB80380 in HBeAg-positive patients with chronic hepatitis B
-
[PMID: 17302367]
-
Yuen MF, Kim J, Kim CR, Ngai V, Yuen JC, Min C, Kang HM, Shin BS, Yoo SD, Lai CL. A randomized placebo controlled, dose-finding study of oral LB80380 in HBeAg-positive patients with chronic hepatitis B. Antivir Ther 2006; 11: 977-983 [PMID: 17302367]
-
(2006)
Antivir Ther
, vol.11
, pp. 977-983
-
-
Yuen, M.F.1
Kim, J.2
Kim, C.R.3
Ngai, V.4
Yuen, J.C.5
Min, C.6
Kang, H.M.7
Shin, B.S.8
Yoo, S.D.9
Lai, C.L.10
-
37
-
-
77950606642
-
Antiviral activity and safety of LB80380 in hepatitis B e antigen-positive chronic hepatitis B patients with lamivudine-resistant disease
-
[PMID: 20091678 DOI: 10.1002/hep.23462]
-
Yuen MF, Han KH, Um SH, Yoon SK, Kim HR, Kim J, Kim CR, Lai CL. Antiviral activity and safety of LB80380 in hepatitis B e antigen-positive chronic hepatitis B patients with lamivudine-resistant disease. Hepatology 2010; 51: 767-776 [PMID: 20091678 DOI: 10.1002/hep.23462]
-
(2010)
Hepatology
, vol.51
, pp. 767-776
-
-
Yuen, M.F.1
Han, K.H.2
Um, S.H.3
Yoon, S.K.4
Kim, H.R.5
Kim, J.6
Kim, C.R.7
Lai, C.L.8
-
38
-
-
84899984444
-
Phase IIb multicentred randomised trial of besifovir (LB80380) versus entecavir in Asian patients with chronic hepatitis B
-
[PMID: 23979965 DOI: 10.1136/gutjnl-2013-305138]
-
Lai CL, Ahn SH, Lee KS, Um SH, Cho M, Yoon SK, Lee JW, Park NH, Kweon YO, Sohn JH, Lee J, Kim JA, Han KH, Yuen MF. Phase IIb multicentred randomised trial of besifovir (LB80380) versus entecavir in Asian patients with chronic hepatitis B. Gut 2014; 63: 996-1004 [PMID: 23979965 DOI: 10.1136/gutjnl-2013-305138]
-
(2014)
Gut
, vol.63
, pp. 996-1004
-
-
Lai, C.L.1
Ahn, S.H.2
Lee, K.S.3
Um, S.H.4
Cho, M.5
Yoon, S.K.6
Lee, J.W.7
Park, N.H.8
Kweon, Y.O.9
Sohn, J.H.10
Lee, J.11
Kim, J.A.12
Han, K.H.13
Yuen, M.F.14
-
39
-
-
18244398917
-
Selective intracellular activation of a novel prodrug of the human immunodeficiency virus reverse transcriptase inhibitor tenofovir leads to preferential distribution and accumulation in lymphatic tissue
-
[PMID: 15855512]
-
Lee WA, He GX, Eisenberg E, Cihlar T, Swaminathan S, Mulato A, Cundy KC. Selective intracellular activation of a novel prodrug of the human immunodeficiency virus reverse transcriptase inhibitor tenofovir leads to preferential distribution and accumulation in lymphatic tissue. Antimicrob Agents Chemother 2005; 49: 1898-1906 [PMID: 15855512]
-
(2005)
Antimicrob Agents Chemother
, vol.49
, pp. 1898-1906
-
-
Lee, W.A.1
He, G.X.2
Eisenberg, E.3
Cihlar, T.4
Swaminathan, S.5
Mulato, A.6
Cundy, K.C.7
-
40
-
-
45749091322
-
Activation of 9-[(R)-2-[[(S)-[[(S)-1 (Isopropoxycarbonyl)ethyl]amino] phenoxyphosphinyl] methoxy]propyl]adenine (GS-7340) and other tenofovir phosphonoamidate prodrugs by human proteases
-
[PMID: 18430788 DOI: 10.1124/ mol.108.045526]
-
Birkus G, Kutty N, He GX, Mulato A, Lee W, McDermott M, Cihlar T. Activation of 9-[(R)-2-[[(S)-[[(S)-1 (Isopropoxycarbonyl)ethyl]amino] phenoxyphosphinyl] methoxy]propyl]adenine (GS-7340) and other tenofovir phosphonoamidate prodrugs by human proteases. Mol Pharmacol 2008; 74: 92-100 [PMID: 18430788 DOI: 10.1124/ mol.108.045526]
-
(2008)
Mol Pharmacol
, vol.74
, pp. 92-100
-
-
Birkus, G.1
Kutty, N.2
He, G.X.3
Mulato, A.4
Lee, W.5
McDermott, M.6
Cihlar, T.7
-
41
-
-
80052070000
-
Natural substrate concentrations can modulate the prophylactic efficacy of nucleotide HIV reverse transcriptase inhibitors
-
[PMID: 21525346 DOI: 10.1128/JVI.00311-11]
-
García-Lerma JG, Aung W, Cong ME, Zheng Q, Youngpairoj AS, Mitchell J, Holder A, Martin A, Kuklenyik S, Luo W, Lin CY, Hanson DL, Kersh E, Pau CP, Ray AS, Rooney JF, Lee WA, Heneine W. Natural substrate concentrations can modulate the prophylactic efficacy of nucleotide HIV reverse transcriptase inhibitors. J Virol 2011; 85: 6610-6617 [PMID: 21525346 DOI: 10.1128/JVI.00311-11]
-
(2011)
J Virol
, vol.85
, pp. 6610-6617
-
-
García-Lerma, J.G.1
Aung, W.2
Cong, M.E.3
Zheng, Q.4
Youngpairoj, A.S.5
Mitchell, J.6
Holder, A.7
Martin, A.8
Kuklenyik, S.9
Luo, W.10
Lin, C.Y.11
Hanson, D.L.12
Kersh, E.13
Pau, C.P.14
Ray, A.S.15
Rooney, J.F.16
Lee, W.A.17
Heneine, W.18
-
42
-
-
34948857943
-
Evaluation of hexadecyloxypropyl-9-R-[2-(Phosphonomethoxy)propyl] adenine, CMX157, as a potential treatment for human immunodeficiency virus type 1 and hepatitis B virus infections
-
[PMID: 17646420]
-
Painter GR, Almond MR, Trost LC, Lampert BM, Neyts J, De Clercq E, Korba BE, Aldern KA, Beadle JR, Hostetler KY. Evaluation of hexadecyloxypropyl-9-R-[2-(Phosphonomethoxy)propyl] adenine, CMX157, as a potential treatment for human immunodeficiency virus type 1 and hepatitis B virus infections. Antimicrob Agents Chemother 2007; 51: 3505-3509 [PMID: 17646420]
-
(2007)
Antimicrob Agents Chemother
, vol.51
, pp. 3505-3509
-
-
Painter, G.R.1
Almond, M.R.2
Trost, L.C.3
Lampert, B.M.4
Neyts, J.5
de Clercq, E.6
Korba, B.E.7
Aldern, K.A.8
Beadle, J.R.9
Hostetler, K.Y.10
-
43
-
-
0037180522
-
Infection of a human hepatoma cell line by hepatitis B virus
-
[PMID: 12432097]
-
Gripon P, Rumin S, Urban S, Le Seyec J, Glaise D, Cannie I, Guyomard C, Lucas J, Trepo C, Guguen-Guillouzo C. Infection of a human hepatoma cell line by hepatitis B virus. Proc Natl Acad Sci USA 2002; 99: 15655-15660 [PMID: 12432097]
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 15655-15660
-
-
Gripon, P.1
Rumin, S.2
Urban, S.3
Le Seyec, J.4
Glaise, D.5
Cannie, I.6
Guyomard, C.7
Lucas, J.8
Trepo, C.9
Guguen-Guillouzo, C.10
-
44
-
-
22544433180
-
Mapping of the hepatitis B virus pre-S1 domain involved in receptor recognition
-
[PMID: 16014940]
-
Barrera A, Guerra B, Notvall L, Lanford RE. Mapping of the hepatitis B virus pre-S1 domain involved in receptor recognition. J Virol 2005; 79: 9786-9798 [PMID: 16014940]
-
(2005)
J Virol
, vol.79
, pp. 9786-9798
-
-
Barrera, A.1
Guerra, B.2
Notvall, L.3
Lanford, R.E.4
-
45
-
-
22344442543
-
Mapping of the hepatitis B virus attachment site by use of infection-inhibiting preS1 lipopeptides and tupaia hepatocytes
-
[PMID: 16012950]
-
Glebe D, Urban S, Knoop EV, Cag N, Krass P, Grün S, Bulavaite A, Sasnauskas K, Gerlich WH. Mapping of the hepatitis B virus attachment site by use of infection-inhibiting preS1 lipopeptides and tupaia hepatocytes. Gastroenterology 2005; 129: 234-245 [PMID: 16012950]
-
(2005)
Gastroenterology
, vol.129
, pp. 234-245
-
-
Glebe, D.1
Urban, S.2
Knoop, E.V.3
Cag, N.4
Krass, P.5
Grün, S.6
Bulavaite, A.7
Sasnauskas, K.8
Gerlich, W.H.9
-
46
-
-
75449106643
-
Fine mapping of pre-S sequence requirements for hepatitis B virus large envelope protein-mediated receptor interaction
-
[PMID: 20007265 DOI: 10.1128/JVI.01902-09]
-
Schulze A, Schieck A, Ni Y, Mier W, Urban S. Fine mapping of pre-S sequence requirements for hepatitis B virus large envelope protein-mediated receptor interaction. J Virol 2010; 84: 1989-2000 [PMID: 20007265 DOI: 10.1128/JVI.01902-09]
-
(2010)
J Virol
, vol.84
, pp. 1989-2000
-
-
Schulze, A.1
Schieck, A.2
Ni, Y.3
Mier, W.4
Urban, S.5
-
47
-
-
40449096921
-
Prevention of hepatitis B virus infection in vivo by entry inhibitors derived from the large envelope protein
-
[PMID: 18297057 DOI: 10.1038/nbt1389]
-
Petersen J, Dandri M, Mier W, Lütgehetmann M, Volz T, von Weizsäcker F, Haberkorn U, Fischer L, Pollok JM, Erbes B, Seitz S, Urban S. Prevention of hepatitis B virus infection in vivo by entry inhibitors derived from the large envelope protein. Nat Biotechnol 2008; 26: 335-341 [PMID: 18297057 DOI: 10.1038/nbt1389]
-
(2008)
Nat Biotechnol
, vol.26
, pp. 335-341
-
-
Petersen, J.1
Dandri, M.2
Mier, W.3
Lütgehetmann, M.4
Volz, T.5
von Weizsäcker, F.6
Haberkorn, U.7
Fischer, L.8
Pollok, J.M.9
Erbes, B.10
Seitz, S.11
Urban, S.12
-
48
-
-
84876295707
-
The entry inhibitor Myrcludex-B efficiently blocks intrahepatic virus spreading in humanized mice previously infected with hepatitis B virus
-
[PMID: 23246506 DOI: 10.1016/j.jhep.2012.12.008]
-
Volz T, Allweiss L, Ben MBarek M, Warlich M, Lohse AW, Pollok JM, Alexandrov A, Urban S, Petersen J, Lütgehetmann M, Dandri M. The entry inhibitor Myrcludex-B efficiently blocks intrahepatic virus spreading in humanized mice previously infected with hepatitis B virus. J Hepatol 2013; 58: 861-867 [PMID: 23246506 DOI: 10.1016/j.jhep.2012.12.008]
-
(2013)
J Hepatol
, vol.58
, pp. 861-867
-
-
Volz, T.1
Allweiss, L.2
Ben, M.M.3
Warlich, M.4
Lohse, A.W.5
Pollok, J.M.6
Alexandrov, A.7
Urban, S.8
Petersen, J.9
Lütgehetmann, M.10
Dandri, M.11
-
49
-
-
84878836923
-
Successful first administration of Myrcludex B, a first-in-class Hepatitis B and D Virus entry inhibitor, in humans
-
Supplement
-
Haefeli WE, Blank A, Mikus G, Mier W, Alexandrov A, Urban S. Successful first administration of Myrcludex B, a first-in-class Hepatitis B and D Virus entry inhibitor, in humans. Hepatology 2012; 56 Supplement: 369
-
(2012)
Hepatology
, vol.56
, pp. 369
-
-
Haefeli, W.E.1
Blank, A.2
Mikus, G.3
Mier, W.4
Alexandrov, A.5
Urban, S.6
-
50
-
-
33645989987
-
Characterization of a hepatitis B and hepatitis delta virus receptor binding site
-
[PMID: 16557545]
-
Engelke M, Mills K, Seitz S, Simon P, Gripon P, Schnölzer M, Urban S. Characterization of a hepatitis B and hepatitis delta virus receptor binding site. Hepatology 2006; 43: 750-760 [PMID: 16557545]
-
(2006)
Hepatology
, vol.43
, pp. 750-760
-
-
Engelke, M.1
Mills, K.2
Seitz, S.3
Simon, P.4
Gripon, P.5
Schnölzer, M.6
Urban, S.7
-
51
-
-
84857442747
-
Humanized chimeric uPA mouse model for the study of hepatitis B and D virus interactions and preclinical drug evaluation
-
[PMID: 22031488 DOI: 10.1002/hep.24758]
-
Lütgehetmann M, Mancke LV, Volz T, Helbig M, Allweiss L, Bornscheuer T, Pollok JM, Lohse AW, Petersen J, Urban S, Dandri M. Humanized chimeric uPA mouse model for the study of hepatitis B and D virus interactions and preclinical drug evaluation. Hepatology 2012; 55: 685-694 [PMID: 22031488 DOI: 10.1002/hep.24758]
-
(2012)
Hepatology
, vol.55
, pp. 685-694
-
-
Lütgehetmann, M.1
Mancke, L.V.2
Volz, T.3
Helbig, M.4
Allweiss, L.5
Bornscheuer, T.6
Pollok, J.M.7
Lohse, A.W.8
Petersen, J.9
Urban, S.10
Dandri, M.11
-
52
-
-
0036227850
-
Inhibition of human hepatitis B virus (HBV) by a novel non-nucleosidic compound in a transgenic mouse model
-
[PMID: 12062392]
-
Weber O, Schlemmer KH, Hartmann E, Hagelschuer I, Paessens A, Graef E, Deres K, Goldmann S, Niewoehner U, Stoltefuss J, Haebich D, Ruebsamen-Waigmann H, Wohlfeil S. Inhibition of human hepatitis B virus (HBV) by a novel non-nucleosidic compound in a transgenic mouse model. Antiviral Res 2002; 54: 69-78 [PMID: 12062392]
-
(2002)
Antiviral Res
, vol.54
, pp. 69-78
-
-
Weber, O.1
Schlemmer, K.H.2
Hartmann, E.3
Hagelschuer, I.4
Paessens, A.5
Graef, E.6
Deres, K.7
Goldmann, S.8
Niewoehner, U.9
Stoltefuss, J.10
Haebich, D.11
Ruebsamen-Waigmann, H.12
Wohlfeil, S.13
-
53
-
-
0347928672
-
Inhibition of hepatitis B virus replication by drug-induced depletion of nucleocapsids
-
[PMID: 12574631]
-
Deres K, Schröder CH, Paessens A, Goldmann S, Hacker HJ, Weber O, Krämer T, Niewöhner U, Pleiss U, Stoltefuss J, Graef E, Koletzki D, Masantschek RN, Reimann A, Jaeger R, Gross R, Beckermann B, Schlemmer KH, Haebich D, Rübsamen-Waigmann H. Inhibition of hepatitis B virus replication by drug-induced depletion of nucleocapsids. Science 2003; 299: 893-896 [PMID: 12574631]
-
(2003)
Science
, vol.299
, pp. 893-896
-
-
Deres, K.1
Schröder, C.H.2
Paessens, A.3
Goldmann, S.4
Hacker, H.J.5
Weber, O.6
Krämer, T.7
Niewöhner, U.8
Pleiss, U.9
Stoltefuss, J.10
Graef, E.11
Koletzki, D.12
Masantschek, R.N.13
Reimann, A.14
Jaeger, R.15
Gross, R.16
Beckermann, B.17
Schlemmer, K.H.18
Haebich, D.19
Rübsamen-Waigmann, H.20
more..
-
54
-
-
52249120971
-
Inhibition of hepatitis B virus replication by Bay 41-4109 and its association with nucleocapsid disassembly
-
[PMID: 18676226]
-
Wu GY, Zheng XJ, Yin CC, Jiang D, Zhu L, Liu Y, Wei L, Wang Y, Chen HS. Inhibition of hepatitis B virus replication by Bay 41-4109 and its association with nucleocapsid disassembly. J Chemother 2008; 20: 458-467 [PMID: 18676226]
-
(2008)
J Chemother
, vol.20
, pp. 458-467
-
-
Wu, G.Y.1
Zheng, X.J.2
Yin, C.C.3
Jiang, D.4
Zhu, L.5
Liu, Y.6
Wei, L.7
Wang, Y.8
Chen, H.S.9
-
55
-
-
82655183566
-
Antiviral activity of Bay 41-4109 on hepatitis B virus in humanized Alb-uPA/SCID mice
-
[PMID: 22162746 DOI: 10.1371/journal.pone.0025096]
-
Brezillon N, Brunelle MN, Massinet H, Giang E, Lamant C, DaSilva L, Berissi S, Belghiti J, Hannoun L, Puerstinger G, Wimmer E, Neyts J, Hantz O, Soussan P, Morosan S, Kremsdorf D. Antiviral activity of Bay 41-4109 on hepatitis B virus in humanized Alb-uPA/SCID mice. PLoS One 2011; 6: e25096 [PMID: 22162746 DOI: 10.1371/journal.pone.0025096]
-
(2011)
PLoS One
, vol.6
-
-
Brezillon, N.1
Brunelle, M.N.2
Massinet, H.3
Giang, E.4
Lamant, C.5
Dasilva, L.6
Berissi, S.7
Belghiti, J.8
Hannoun, L.9
Puerstinger, G.10
Wimmer, E.11
Neyts, J.12
Hantz, O.13
Soussan, P.14
Morosan, S.15
Kremsdorf, D.16
-
56
-
-
20444421508
-
A heteroaryldihydropyrimidine activates and can misdirect hepatitis B virus capsid assembly
-
[PMID: 15928089]
-
Stray SJ, Bourne CR, Punna S, Lewis WG, Finn MG, Zlotnick A. A heteroaryldihydropyrimidine activates and can misdirect hepatitis B virus capsid assembly. Proc Natl Acad Sci USA 2005; 102: 8138-8143 [PMID: 15928089]
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 8138-8143
-
-
Stray, S.J.1
Bourne, C.R.2
Punna, S.3
Lewis, W.G.4
Finn, M.G.5
Zlotnick, A.6
-
57
-
-
33845868485
-
BAY 41-4109 has multiple effects on Hepatitis B virus capsid assembly
-
[PMID: 17006877]
-
Stray SJ, Zlotnick A. BAY 41-4109 has multiple effects on Hepatitis B virus capsid assembly. J Mol Recognit 2006; 19: 542-548 [PMID: 17006877]
-
(2006)
J Mol Recognit
, vol.19
, pp. 542-548
-
-
Stray, S.J.1
Zlotnick, A.2
-
58
-
-
84865773658
-
In vitro inhibition of HBV replication by a novel compound, GLS4, and its efficacy against adefovir-dipivoxil-resistant HBV mutations
-
[PMID: 22668794 DOI: 10.3851/IMP2152]
-
Wang XY, Wei ZM, Wu GY, Wang JH, Zhang YJ, Li J, Zhang HH, Xie XW, Wang X, Wang ZH, Wei L, Wang Y, Chen HS. In vitro inhibition of HBV replication by a novel compound, GLS4, and its efficacy against adefovir-dipivoxil-resistant HBV mutations. Antivir Ther 2012; 17: 793-803 [PMID: 22668794 DOI: 10.3851/IMP2152]
-
(2012)
Antivir Ther
, vol.17
, pp. 793-803
-
-
Wang, X.Y.1
Wei, Z.M.2
Wu, G.Y.3
Wang, J.H.4
Zhang, Y.J.5
Li, J.6
Zhang, H.H.7
Xie, X.W.8
Wang, X.9
Wang, Z.H.10
Wei, L.11
Wang, Y.12
Chen, H.S.13
-
59
-
-
0031758695
-
Inhibition of human hepatitis B virus replication by AT-61, a phenylpropenamide derivative, alone and in combination with (-)beta-L-2',3'-dideoxy-3'-thiacytidine
-
[PMID: 9835512]
-
King RW, Ladner SK, Miller TJ, Zaifert K, Perni RB, Conway SC, Otto MJ. Inhibition of human hepatitis B virus replication by AT-61, a phenylpropenamide derivative, alone and in combination with (-)beta-L-2',3'-dideoxy-3'-thiacytidine. Antimicrob Agents Chemother 1998; 42: 3179-3186 [PMID: 9835512]
-
(1998)
Antimicrob Agents Chemother
, vol.42
, pp. 3179-3186
-
-
King, R.W.1
Ladner, S.K.2
Miller, T.J.3
Zaifert, K.4
Perni, R.B.5
Conway, S.C.6
Otto, M.J.7
-
60
-
-
0036721178
-
Phenylpropenamide derivatives AT-61 and AT-130 inhibit replication of wild-type and lamivudine-resistant strains of hepatitis B virus in vitro
-
[PMID: 12183271]
-
Delaney WE, Edwards R, Colledge D, Shaw T, Furman P, Painter G, Locarnini S. Phenylpropenamide derivatives AT-61 and AT-130 inhibit replication of wild-type and lamivudine-resistant strains of hepatitis B virus in vitro. Antimicrob Agents Chemother 2002; 46: 3057-3060 [PMID: 12183271]
-
(2002)
Antimicrob Agents Chemother
, vol.46
, pp. 3057-3060
-
-
Delaney, W.E.1
Edwards, R.2
Colledge, D.3
Shaw, T.4
Furman, P.5
Painter, G.6
Locarnini, S.7
-
61
-
-
34548641466
-
The phenylpropenamide derivative AT-130 blocks HBV replication at the level of viral RNA packaging
-
[PMID: 17709147]
-
Feld JJ, Colledge D, Sozzi V, Edwards R, Littlejohn M, Locarnini SA. The phenylpropenamide derivative AT-130 blocks HBV replication at the level of viral RNA packaging. Antiviral Res 2007; 76: 168-177 [PMID: 17709147]
-
(2007)
Antiviral Res
, vol.76
, pp. 168-177
-
-
Feld, J.J.1
Colledge, D.2
Sozzi, V.3
Edwards, R.4
Littlejohn, M.5
Locarnini, S.A.6
-
62
-
-
78650580448
-
Trapping of hepatitis B virus capsid assembly intermediates by phenylpropenamide assembly accelerators
-
[PMID: 20845949 DOI: 10.1021/cb100275b]
-
Katen SP, Chirapu SR, Finn MG, Zlotnick A. Trapping of hepatitis B virus capsid assembly intermediates by phenylpropenamide assembly accelerators. ACS Chem Biol 2010; 5: 1125-1136 [PMID: 20845949 DOI: 10.1021/cb100275b]
-
(2010)
ACS Chem Biol
, vol.5
, pp. 1125-1136
-
-
Katen, S.P.1
Chirapu, S.R.2
Finn, M.G.3
Zlotnick, A.4
-
63
-
-
0029821897
-
Inhibition of human cytomegalovirus immediate-early gene expression by an antisense oligonucleotide complementary to immediate-early RNA
-
[PMID: 8878571]
-
Anderson KP, Fox MC, Brown-Driver V, Martin MJ, Azad RF. Inhibition of human cytomegalovirus immediate-early gene expression by an antisense oligonucleotide complementary to immediate-early RNA. Antimicrob Agents Chemother 1996; 40: 2004-2011 [PMID: 8878571]
-
(1996)
Antimicrob Agents Chemother
, vol.40
, pp. 2004-2011
-
-
Anderson, K.P.1
Fox, M.C.2
Brown-Driver, V.3
Martin, M.J.4
Azad, R.F.5
-
64
-
-
33645781308
-
Phosphorothioate oligonucleotides inhibit human immunodeficiency virus type 1 fusion by blocking gp41 core formation
-
[PMID: 16569857]
-
Vaillant A, Juteau JM, Lu H, Liu S, Lackman-Smith C, Ptak R, Jiang S. Phosphorothioate oligonucleotides inhibit human immunodeficiency virus type 1 fusion by blocking gp41 core formation. Antimicrob Agents Chemother 2006; 50: 1393-1401 [PMID: 16569857]
-
(2006)
Antimicrob Agents Chemother
, vol.50
, pp. 1393-1401
-
-
Vaillant, A.1
Juteau, J.M.2
Lu, H.3
Liu, S.4
Lackman-Smith, C.5
Ptak, R.6
Jiang, S.7
-
65
-
-
38049000726
-
Amphipathic DNA polymers are candidate vaginal microbicides and block herpes simplex virus binding, entry and viral gene expression
-
[PMID: 18240855]
-
Guzman EM, Cheshenko N, Shende V, Keller MJ, Goyette N, Juteau JM, Boivin G, Vaillant A, Herold BC. Amphipathic DNA polymers are candidate vaginal microbicides and block herpes simplex virus binding, entry and viral gene expression. Antivir Ther 2007; 12: 1147-1156 [PMID: 18240855]
-
(2007)
Antivir Ther
, vol.12
, pp. 1147-1156
-
-
Guzman, E.M.1
Cheshenko, N.2
Shende, V.3
Keller, M.J.4
Goyette, N.5
Juteau, J.M.6
Boivin, G.7
Vaillant, A.8
Herold, B.C.9
-
66
-
-
48749128890
-
Amphipathic DNA polymers exhibit antiherpetic activity in vitro and in vivo
-
[PMID: 18505857]
-
Bernstein DI, Goyette N, Cardin R, Kern ER, Boivin G, Ireland J, Juteau JM, Vaillant A. Amphipathic DNA polymers exhibit antiherpetic activity in vitro and in vivo. Antimicrob Agents Chemother 2008; 52: 2727-2733 [PMID: 18505857]
-
(2008)
Antimicrob Agents Chemother
, vol.52
, pp. 2727-2733
-
-
Bernstein, D.I.1
Goyette, N.2
Cardin, R.3
Kern, E.R.4
Boivin, G.5
Ireland, J.6
Juteau, J.M.7
Vaillant, A.8
-
67
-
-
74949085441
-
Amphipathic DNA polymers exhibit antiviral activity against systemic murine Cytomegalovirus infection
-
[PMID: 19954538 DOI: 10.1186/1743-422X-6-214]
-
Cardin RD, Bravo FJ, Sewell AP, Cummins J, Flamand L, Juteau JM, Bernstein DI, Vaillant A. Amphipathic DNA polymers exhibit antiviral activity against systemic murine Cytomegalovirus infection. Virol J 2009; 6: 214 [PMID: 19954538 DOI: 10.1186/1743-422X-6-214]
-
(2009)
Virol J
, vol.6
, pp. 214
-
-
Cardin, R.D.1
Bravo, F.J.2
Sewell, A.P.3
Cummins, J.4
Flamand, L.5
Juteau, J.M.6
Bernstein, D.I.7
Vaillant, A.8
Amphipathic, D.N.A.9
-
68
-
-
38949217075
-
Inhibition of cellular entry of lymphocytic choriomeningitis virus by amphipathic DNA polymers
-
[PMID: 18022208]
-
Lee AM, Rojek JM, Gundersen A, Ströher U, Juteau JM, Vaillant A, Kunz S. Inhibition of cellular entry of lymphocytic choriomeningitis virus by amphipathic DNA polymers. Virology 2008; 372: 107-117 [PMID: 18022208]
-
(2008)
Virology
, vol.372
, pp. 107-117
-
-
Lee, A.M.1
Rojek, J.M.2
Gundersen, A.3
Ströher, U.4
Juteau, J.M.5
Vaillant, A.6
Kunz, S.7
-
69
-
-
67650973623
-
Amphipathic DNA polymers inhibit hepatitis C virus infection by blocking viral entry
-
[PMID: 19394333 DOI: 10.1053/ j.gastro.2009.04.048]
-
Matsumura T, Hu Z, Kato T, Dreux M, Zhang YY, Imamura M, Hiraga N, Juteau JM, Cosset FL, Chayama K, Vaillant A, Liang TJ. Amphipathic DNA polymers inhibit hepatitis C virus infection by blocking viral entry. Gastroenterology 2009; 137: 673-681 [PMID: 19394333 DOI: 10.1053/ j.gastro.2009.04.048]
-
(2009)
Gastroenterology
, vol.137
, pp. 673-681
-
-
Matsumura, T.1
Hu, Z.2
Kato, T.3
Dreux, M.4
Zhang, Y.Y.5
Imamura, M.6
Hiraga, N.7
Juteau, J.M.8
Cosset, F.L.9
Chayama, K.10
Vaillant, A.11
Liang, T.J.12
-
70
-
-
84938865465
-
REP 9 AC: A potent HBsAg release inhibitor that elicits durable immunological control of chronic HBV infection
-
Mahtab MA, Bazinet M, Vaillant A. REP 9 AC: a potent HBsAg release inhibitor that elicits durable immunological control of chronic HBV infection. Hepatology 2011; 54 (Suppl S1): 478A
-
(2011)
Hepatology
, vol.54
, Issue.SUPPL. S1
-
-
Mahtab, M.A.1
Bazinet, M.2
Vaillant, A.3
-
71
-
-
84865714540
-
Nucleic acid polymers REP 9 AC/REP 9 AC' elicit sustained immunologic control of chronic HBV infection
-
Mahtab MA, Bazinet M, Patient R, Roingeard P, Vaillant A. Nucleic acid polymers REP 9 AC/REP 9 AC' elicit sustained immunologic control of chronic HBV infection. Glob Antiviral J 2011; 7 Suppl 1: 64A
-
(2011)
Glob Antiviral J
, vol.7
, Issue.SUPPL. 1
-
-
Mahtab, M.A.1
Bazinet, M.2
Patient, R.3
Roingeard, P.4
Vaillant, A.5
-
72
-
-
34548345811
-
Nitazoxanide: A review of its use in the treatment of gastrointestinal infections
-
[PMID: 17722965]
-
Anderson VR, Curran MP. Nitazoxanide: a review of its use in the treatment of gastrointestinal infections. Drugs 2007; 67: 1947-1967 [PMID: 17722965]
-
(2007)
Drugs
, vol.67
, pp. 1947-1967
-
-
Anderson, V.R.1
Curran, M.P.2
-
73
-
-
37449014458
-
Nitazoxanide, tizoxanide and other thiazolides are potent inhibitors of hepatitis B virus and hepatitis C virus replication
-
[PMID: 17888524]
-
Korba BE, Montero AB, Farrar K, Gaye K, Mukerjee S, Ayers MS, Rossignol JF. Nitazoxanide, tizoxanide and other thiazolides are potent inhibitors of hepatitis B virus and hepatitis C virus replication. Antiviral Res 2008; 77: 56-63 [PMID: 17888524]
-
(2008)
Antiviral Res
, vol.77
, pp. 56-63
-
-
Korba, B.E.1
Montero, A.B.2
Farrar, K.3
Gaye, K.4
Mukerjee, S.5
Ayers, M.S.6
Rossignol, J.F.7
-
74
-
-
55449122030
-
Thiazolides: A new class of drugs for the treatment of chronic hepatitis B and C
-
[PMID: 18811238 DOI: 10.2217/17460913 3.5.539]
-
Rossignol JF, Keeffe EB. Thiazolides: a new class of drugs for the treatment of chronic hepatitis B and C. Future Microbiol 2008; 3: 539-545 [PMID: 18811238 DOI: 10.2217/17460913 3.5.539]
-
(2008)
Future Microbiol
, vol.3
, pp. 539-545
-
-
Rossignol, J.F.1
Keeffe, E.B.2
-
75
-
-
67651251216
-
Treatment of chronic viral hepatitis with nitazoxanide and second generation thiazolides
-
[PMID: 19370775]
-
Keeffe EB, Rossignol JF. Treatment of chronic viral hepatitis with nitazoxanide and second generation thiazolides. World J Gastroenterol 2009; 15: 1805-1808 [PMID: 19370775]
-
(2009)
World J Gastroenterol
, vol.15
, pp. 1805-1808
-
-
Keeffe, E.B.1
Rossignol, J.F.2
-
76
-
-
0032545933
-
Potent and specific genetic interference by doublestranded RNA in Caenorhabditis elegans
-
[PMID: 9486653]
-
Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC. Potent and specific genetic interference by doublestranded RNA in Caenorhabditis elegans. Nature 1998; 391: 806-811 [PMID: 9486653]
-
(1998)
Nature
, vol.391
, pp. 806-811
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
Kostas, S.A.4
Driver, S.E.5
Mello, C.C.6
-
77
-
-
72249103457
-
Does RNA interference provide new hope for control of chronic hepatitis B infection?
-
[PMID: 19918092 DOI: 10.3851/IMP1424]
-
Wilson R, Purcell D, Netter HJ, Revill PA. Does RNA interference provide new hope for control of chronic hepatitis B infection? Antivir Ther 2009; 14: 879-889 [PMID: 19918092 DOI: 10.3851/IMP1424]
-
(2009)
Antivir Ther
, vol.14
, pp. 879-889
-
-
Wilson, R.1
Purcell, D.2
Netter, H.J.3
Revill, P.A.4
-
78
-
-
0038449221
-
Inhibition of hepatitis B virus replication in vivo by nucleoside analogues and siRNA
-
[PMID: 12851866]
-
Klein C, Bock CT, Wedemeyer H, Wüstefeld T, Locarnini S, Dienes HP, Kubicka S, Manns MP, Trautwein C. Inhibition of hepatitis B virus replication in vivo by nucleoside analogues and siRNA. Gastroenterology 2003; 125: 9-18 [PMID: 12851866]
-
(2003)
Gastroenterology
, vol.125
, pp. 9-18
-
-
Klein, C.1
Bock, C.T.2
Wedemeyer, H.3
Wüstefeld, T.4
Locarnini, S.5
Dienes, H.P.6
Kubicka, S.7
Manns, M.P.8
Trautwein, C.9
-
79
-
-
0038023197
-
Inhibition of hepatitis B virus in mice by RNA interference
-
[PMID: 12740585]
-
McCaffrey AP, Nakai H, Pandey K, Huang Z, Salazar FH, Xu H, Wieland SF, Marion PL, Kay MA. Inhibition of hepatitis B virus in mice by RNA interference. Nat Biotechnol 2003; 21: 639-644 [PMID: 12740585]
-
(2003)
Nat Biotechnol
, vol.21
, pp. 639-644
-
-
McCaffrey, A.P.1
Nakai, H.2
Pandey, K.3
Huang, Z.4
Salazar, F.H.5
Xu, H.6
Wieland, S.F.7
Marion, P.L.8
Kay, M.A.9
-
80
-
-
23444445660
-
Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs
-
[PMID: 16041363]
-
Morrissey DV, Lockridge JA, Shaw L, Blanchard K, Jensen K, Breen W, Hartsough K, Machemer L, Radka S, Jadhav V, Vaish N, Zinnen S, Vargeese C, Bowman K, Shaffer CS, Jeffs LB, Judge A, MacLachlan I, Polisky B. Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs. Nat Biotechnol 2005; 23: 1002-1007 [PMID: 16041363]
-
(2005)
Nat Biotechnol
, vol.23
, pp. 1002-1007
-
-
Morrissey, D.V.1
Lockridge, J.A.2
Shaw, L.3
Blanchard, K.4
Jensen, K.5
Breen, W.6
Hartsough, K.7
Machemer, L.8
Radka, S.9
Jadhav, V.10
Vaish, N.11
Zinnen, S.12
Vargeese, C.13
Bowman, K.14
Shaffer, C.S.15
Jeffs, L.B.16
Judge, A.17
Maclachlan, I.18
Polisky, B.19
-
81
-
-
84948448959
-
ARC-520 RNAi therapeutic reduces hepatitis B virus DNA, S antigen and e antigen in a chimpanzee with a very high viral titer
-
Lanford RE, Wooddell CI, Chavez D, Oropeza C, Chu Q, Hamilton HL, McLachlan A, Given B, Anzalone CR, Lewis DL. ARC-520 RNAi therapeutic reduces hepatitis B virus DNA, S antigen and e antigen in a chimpanzee with a very high viral titer. Hepatology 2013; 58 (Suppl S1): 1305
-
(2013)
Hepatology
, vol.58
, Issue.SUPPL. S1
, pp. 1305
-
-
Lanford, R.E.1
Wooddell, C.I.2
Chavez, D.3
Oropeza, C.4
Chu, Q.5
Hamilton, H.L.6
McLachlan, A.7
Given, B.8
Anzalone, C.R.9
Lewis, D.L.10
-
82
-
-
42049106464
-
Combination therapy of thymosin alpha-1 and lamivudine for HBeAg positive chronic hepatitis B: A prospective randomized, comparative pilot study
-
[PMID: 18410608 DOI: 10.1111/j.1440-1746.2008.05387.x]
-
Lee HW, Lee JI, Um SH, Ahn SH, Chang HY, Park YK, Hong SP, Moon YM, Han KH. Combination therapy of thymosin alpha-1 and lamivudine for HBeAg positive chronic hepatitis B: A prospective randomized, comparative pilot study. J Gastroenterol Hepatol 2008; 23: 729-735 [PMID: 18410608 DOI: 10.1111/j.1440-1746.2008.05387.x]
-
(2008)
J Gastroenterol Hepatol
, vol.23
, pp. 729-735
-
-
Lee, H.W.1
Lee, J.I.2
Um, S.H.3
Ahn, S.H.4
Chang, H.Y.5
Park, Y.K.6
Hong, S.P.7
Moon, Y.M.8
Han, K.H.9
-
83
-
-
38349056857
-
Comparison of the efficacy of thymosin alpha-1 and interferon alpha in the treatment of chronic hepatitis B: A meta-analysis
-
[PMID: 18078676]
-
Yang YF, Zhao W, Zhong YD, Yang YJ, Shen L, Zhang N, Huang P. Comparison of the efficacy of thymosin alpha-1 and interferon alpha in the treatment of chronic hepatitis B: a meta-analysis. Antiviral Res 2008; 77: 136-141 [PMID: 18078676]
-
(2008)
Antiviral Res
, vol.77
, pp. 136-141
-
-
Yang, Y.F.1
Zhao, W.2
Zhong, Y.D.3
Yang, Y.J.4
Shen, L.5
Zhang, N.6
Huang, P.7
-
84
-
-
18744399291
-
Toll-like receptor signaling inhibits hepatitis B virus replication in vivo
-
[PMID: 15890966]
-
Isogawa M, Robek MD, Furuichi Y, Chisari FV. Toll-like receptor signaling inhibits hepatitis B virus replication in vivo. J Virol 2005; 79: 7269-7272 [PMID: 15890966]
-
(2005)
J Virol
, vol.79
, pp. 7269-7272
-
-
Isogawa, M.1
Robek, M.D.2
Furuichi, Y.3
Chisari, F.V.4
-
85
-
-
84878276077
-
GS-9620, an oral agonist of Toll-like receptor-7, induces prolonged suppression of hepatitis B virus in chronically infected chimpanzees
-
[PMID: 23415804 DOI: 10.1053/ j.gastro.2013.02.003]
-
Lanford RE, Guerra B, Chavez D, Giavedoni L, Hodara VL, Brasky KM, Fosdick A, Frey CR, Zheng J, Wolfgang G, Halcomb RL, Tumas DB. GS-9620, an oral agonist of Toll-like receptor-7, induces prolonged suppression of hepatitis B virus in chronically infected chimpanzees. Gastroenterology 2013; 144: 1508-117, [PMID: 23415804 DOI: 10.1053/ j.gastro.2013.02.003]
-
(2013)
Gastroenterology
, vol.144
, pp. 1508-2117
-
-
Lanford, R.E.1
Guerra, B.2
Chavez, D.3
Giavedoni, L.4
Hodara, V.L.5
Brasky, K.M.6
Fosdick, A.7
Frey, C.R.8
Zheng, J.9
Wolfgang, G.10
Halcomb, R.L.11
Tumas, D.B.12
-
86
-
-
84878077286
-
Safety, pharmacokinetics and pharmacodynamics of GS-9620, an oral Toll-like receptor 7 agonist
-
[PMID: 23416308 DOI: 10.3851/ IMP2548]
-
Lopatin U, Wolfgang G, Tumas D, Frey CR, Ohmstede C, Hesselgesser J, Kearney B, Moorehead L, Subramanian GM, McHutchison JG. Safety, pharmacokinetics and pharmacodynamics of GS-9620, an oral Toll-like receptor 7 agonist. Antivir Ther 2013; 18: 409-418 [PMID: 23416308 DOI: 10.3851/ IMP2548]
-
(2013)
Antivir Ther
, vol.18
, pp. 409-418
-
-
Lopatin, U.1
Wolfgang, G.2
Tumas, D.3
Frey, C.R.4
Ohmstede, C.5
Hesselgesser, J.6
Kearney, B.7
Moorehead, L.8
Subramanian, G.M.9
McHutchison, J.G.10
-
87
-
-
84866242385
-
Treatment of chronic hepatitis b infection with DV-601, a therapeutic vaccine
-
Spellman M, Martin JT. Treatment of chronic hepatitis b infection with DV-601, a therapeutic vaccine. J Hepatol 2011; 54 (Suppl 1): s302
-
(2011)
J Hepatol
, vol.54
, Issue.SUPPL. 1
-
-
Spellman, M.1
Martin, J.T.2
|