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Volumn 84, Issue 9, 2010, Pages 4494-4503

Identification and characterization of clevudine-resistant mutants of hepatitis B virus isolated from chronic hepatitis B patients

Author keywords

[No Author keywords available]

Indexed keywords

ADEFOVIR; CLEVUDINE; ENTECAVIR; LAMIVUDINE; RNA DIRECTED DNA POLYMERASE; TENOFOVIR;

EID: 77950821986     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.02066-09     Document Type: Article
Times cited : (41)

References (24)
  • 1
    • 0030045732 scopus 로고    scopus 로고
    • Inhibition of hepatitis B virus by a novel L-nucleoside, 2′-fluoro-5-methylbeta-L-arabinofuranosyl uracil
    • Balakrishna Pai, S., S. H. Liu, Y. L. Zhu, C. K. Chu, and Y. C. Cheng. 1996. Inhibition of hepatitis B virus by a novel L-nucleoside, 2′-fluoro-5-methylbeta-L-arabinofuranosyl uracil. Antimicrob. Agents Chemother. 40:380-386.
    • (1996) Antimicrob. Agents Chemother. , vol.40 , pp. 380-386
    • Balakrishna Pai, S.1    Liu, S.H.2    Zhu, Y.L.3    Chu, C.K.4    Cheng, Y.C.5
  • 3
    • 17944372114 scopus 로고    scopus 로고
    • In vitro susceptibilities of wild-type or drug-resistant hepatitis B virus to (-)-beta-D-2,6-diaminopurine dioxolane and 2′-fluoro-5-methyl- beta-L-arabinofuranosyluracil
    • Chin, R., T. Shaw, J. Torresi, V. Sozzi, C. Trautwein, T. Bock, M. Manns, H. Isom, P. Furman, and S. Locarnini. 2001. In vitro susceptibilities of wild-type or drug-resistant hepatitis B virus to (-)-beta-D-2,6-diaminopurine dioxolane and 2′-fluoro-5-methyl-beta-L-arabinofuranosyluracil. Antimicrob. Agents Chemother. 45:2495-2501.
    • (2001) Antimicrob. Agents Chemother. , vol.45 , pp. 2495-2501
    • Chin, R.1    Shaw, T.2    Torresi, J.3    Sozzi, V.4    Trautwein, C.5    Bock, T.6    Manns, M.7    Isom, H.8    Furman, P.9    Locarnini, S.10
  • 5
    • 0142092372 scopus 로고    scopus 로고
    • The hepatitis B virus polymerase mutation rtV173L is selected during lamivudine therapy and enhances viral replication in vitro
    • Delaney, W. E., IV, H. Yang, C. E. Westland, K. Das, E. Arnold, C. S. Gibbs, M. D. Miller, and S. Xiong. 2003. The hepatitis B virus polymerase mutation rtV173L is selected during lamivudine therapy and enhances viral replication in vitro. J. Virol. 77:11833-11841.
    • (2003) J. Virol. , vol.77 , pp. 11833-11841
    • Delaney, W.E.1    Yang IV, H.2    Westland, C.E.3    Das, K.4    Arnold, E.5    Gibbs, C.S.6    Miller, M.D.7    Xiong, S.8
  • 6
    • 0032525030 scopus 로고    scopus 로고
    • Role of additional mutations outside the YMDD motif of hepatitis B virus polymerase in L(-)SddC (3TC) resistance
    • Fu, L., and Y. C. Cheng. 1998. Role of additional mutations outside the YMDD motif of hepatitis B virus polymerase in L(-)SddC (3TC) resistance. Biochem. Pharmacol. 55:1567-1572.
    • (1998) Biochem. Pharmacol. , vol.55 , pp. 1567-1572
    • Fu, L.1    Cheng, Y.C.2
  • 7
    • 30344471103 scopus 로고    scopus 로고
    • Point mutations upstream of hepatitis B virus core gene affect DNA replication at the step of core protein expression
    • DOI 10.1128/JVI.80.2.587-595.2006
    • Guarnieri, M., K. H. Kim, G. Bang, J. Li, Y. Zhou, X. Tang, J. Wands, and S. Tong. 2006. Point mutations upstream of hepatitis B virus core gene affect DNA replication at the step of core protein expression. J. Virol. 80:587-595. (Pubitemid 43062871)
    • (2006) Journal of Virology , vol.80 , Issue.2 , pp. 587-595
    • Guarnieri, M.1    Kim, K.-H.2    Bang, G.3    Li, J.4    Zhou, Y.5    Tang, X.6    Wands, J.7    Tong, S.8
  • 8
    • 34247194561 scopus 로고    scopus 로고
    • Management of hepatitis B: Summary of a clinical research workshop
    • DOI 10.1002/hep.21627
    • Hoofnagle, J. H., E. Doo, T. J. Liang, R. Fleischer, and A. S. Lok. 2007. Management of hepatitis B: summary of a clinical research workshop. Hepatology 45:1056-1075. (Pubitemid 46646501)
    • (2007) Hepatology , vol.45 , Issue.4 , pp. 1056-1075
    • Hoofnagle, J.H.1    Doo, E.2    Liang, T.J.3    Fleischer, R.4    Lok, A.S.F.5
  • 9
    • 0038558163 scopus 로고    scopus 로고
    • Pro-apoptotic function of HBV X protein is mediated by interaction with c-FLIP and enhancement of death-inducing signal
    • Kim, K. H., and B. L. Seong. 2003. Pro-apoptotic function of HBV X protein is mediated by interaction with c-FLIP and enhancement of death-inducing signal. EMBO J. 22:2104-2116.
    • (2003) EMBO J. , vol.22 , pp. 2104-2116
    • Kim, K.H.1    Seong, B.L.2
  • 10
    • 68549097944 scopus 로고    scopus 로고
    • Clinical and virological responses to clevudine therapy in chronic hepatitis B patients: Results at 1 year of an open-labelled prospective study
    • Ko, S. Y., S. Y. Kwon, W. H. Choe, B. K. Kim, K. H. Kim, and C. H. Lee. 2009. Clinical and virological responses to clevudine therapy in chronic hepatitis B patients: results at 1 year of an open-labelled prospective study. Antivir. Ther. 4:585-590.
    • (2009) Antivir. Ther. , vol.4 , pp. 585-590
    • Ko, S.Y.1    Kwon, S.Y.2    Choe, W.H.3    Kim, B.K.4    Kim, K.H.5    Lee, C.H.6
  • 13
    • 0030707941 scopus 로고    scopus 로고
    • Hepatitis B virus infection
    • Lee, W. M. 1997. Hepatitis B virus infection. N. Engl. J. Med. 337:1733-1745.
    • (1997) N. Engl. J. Med. , vol.337 , pp. 1733-1745
    • Lee, W.M.1
  • 16
    • 0031979178 scopus 로고    scopus 로고
    • Unique metabolism of a novel antiviral L-nucleoside analog, 2′-fluoro-5-methyl-beta-L-arabinofuranosyluracil: A substrate for both thymidine kinase and deoxycytidine kinase
    • Liu, S. H., K. L. Grove, and Y. C. Cheng. 1998. Unique metabolism of a novel antiviral L-nucleoside analog, 2′-fluoro-5-methyl-beta-L- arabinofuranosyluracil: a substrate for both thymidine kinase and deoxycytidine kinase. Antimicrob. Agents Chemother. 42:833-839.
    • (1998) Antimicrob. Agents Chemother. , vol.42 , pp. 833-839
    • Liu, S.H.1    Grove, K.L.2    Cheng, Y.C.3
  • 17
    • 0031938029 scopus 로고    scopus 로고
    • Hepatitis B virus mutants associated with 3TC and Famciclovir administration are replication defective
    • DOI 10.1002/hep.510270243
    • Melegari, M., P. P. Scaglioni, and J. R. Wands. 1998. Hepatitis B virus mutants associated with 3TC and famciclovir administration are replication defective. Hepatology 27:628-633. (Pubitemid 28081083)
    • (1998) Hepatology , vol.27 , Issue.2 , pp. 628-633
    • Melegari, M.1    Scaglioni, P.P.2    Wands, J.R.3
  • 18
    • 0035114188 scopus 로고    scopus 로고
    • The polymerase L528M mutation cooperates with nucleotide binding-site mutations, increasing hepatitis B virus replication and drug resistance
    • Ono, S. K., N. Kato, Y. Shiratori, J. Kato, T. Goto, R. F. Schinazi, F. J. Carrilho, and M. Omata. 2001. The polymerase L528M mutation cooperates with nucleotide binding-site mutations, increasing hepatitis B virus replication and drug resistance. J. Clin. Invest. 107:449-455.
    • (2001) J. Clin. Invest. , vol.107 , pp. 449-455
    • Ono, S.K.1    Kato, N.2    Shiratori, Y.3    Kato, J.4    Goto, T.5    Schinazi, R.F.6    Carrilho, F.J.7    Omata, M.8
  • 21
    • 34447255407 scopus 로고    scopus 로고
    • The L80I substitution in the reverse transcriptase domain of the hepatitis B virus polymerase is associated with lamivudine resistance and enhanced viral replication in vitro
    • Warner, N., S. Locarnini, M. Kuiper, A. Bartholomeusz, A. Ayres, L. Yuen, and T. Shaw. 2007. The L80I substitution in the reverse transcriptase domain of the hepatitis B virus polymerase is associated with lamivudine resistance and enhanced viral replication in vitro. Antimicrob. Agents Chemother. 51:2285-2292.
    • (2007) Antimicrob. Agents Chemother. , vol.51 , pp. 2285-2292
    • Warner, N.1    Locarnini, S.2    Kuiper, M.3    Bartholomeusz, A.4    Ayres, A.5    Yuen, L.6    Shaw, T.7
  • 22
    • 0036147464 scopus 로고    scopus 로고
    • Mutations of the woodchuck hepatitis virus polymerase gene that confer resistance to lamivudine and 2′-fluoro-5-methyl-beta-L- arabinofuranosyluracil
    • Yamamoto, T., S. Litwin, T. Zhou, Y. Zhu, L. Condreay, P. Furman, and W. S. Mason. 2002. Mutations of the woodchuck hepatitis virus polymerase gene that confer resistance to lamivudine and 2′-fluoro-5-methyl-beta-L- arabinofuranosyluracil. J. Virol. 76:1213-1223. (Pubitemid 34066425)
    • (2002) Journal of Virology , vol.76 , Issue.3 , pp. 1213-1223
    • Yamamoto, T.1    Litwin, S.2    Zhou, T.3    Zhu, Y.4    Condreay, L.5    Furman, P.6    Mason, W.S.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.