메뉴 건너뛰기




Volumn 20, Issue 4, 2008, Pages 458-467

Inhibition of hepatitis B virus replication by Bay 41-4109 and its association with nucleocapsid disassembly

Author keywords

Antiviral effects; Bay 41 4109; Core protein; HBV DNA; Hepatitis B

Indexed keywords

ANTIVIRUS AGENT; BAY 41 4109; DIMER; HEPATITIS B CORE ANTIGEN; LAMIVUDINE; METHYL 4 (2 CHLORO 4 FLUOROPHENYL) 2 (3,5 DIFLUORO 2 PYRIDINYL) 6 METHYL 1,4 DIHYDROPYRIMIDINE 5 CARBOXYLATE; MONOMER; NUCLEOCAPSID PROTEIN; UNCLASSIFIED DRUG; VIRUS DNA;

EID: 52249120971     PISSN: 1120009X     EISSN: None     Source Type: Journal    
DOI: 10.1179/joc.2008.20.4.458     Document Type: Article
Times cited : (31)

References (28)
  • 2
    • 0037366464 scopus 로고    scopus 로고
    • Asian-Pacific consensus statement on the management of chronic hepatitis B: An update
    • Liaw YF, Leung N, Guan R, Lau GK, Merican I. Asian-Pacific consensus statement on the management of chronic hepatitis B: an update. J Gastroenterol Hepatol 2003; 18:239-45.
    • (2003) J Gastroenterol Hepatol , vol.18 , pp. 239-245
    • Liaw, Y.F.1    Leung, N.2    Guan, R.3    Lau, G.K.4    Merican, I.5
  • 3
    • 0035010523 scopus 로고    scopus 로고
    • Management of hepatitis B: 2000 - summary of a workshop
    • Lok AS, Heathcote EJ, Hoofnagle JH. Management of hepatitis B: 2000 - summary of a workshop. Gastroenterology 2001; 120:1828-53.
    • (2001) Gastroenterology , vol.120 , pp. 1828-1853
    • Lok, A.S.1    Heathcote, E.J.2    Hoofnagle, J.H.3
  • 4
    • 21244447705 scopus 로고    scopus 로고
    • Peginterferon Alfa-2a, Lamivudine, and the Combination for HBeAg-Positive Chronic Hepatitis B
    • Lau GK, Piratvisuth T, Luo KX, Marcellin P, Thongsawat S, Cooksley G, et al. Peginterferon Alfa-2a, Lamivudine, and the Combination for HBeAg-Positive Chronic Hepatitis B. N Engl J Med 2005; 352:2682-95.
    • (2005) N Engl J Med , vol.352 , pp. 2682-2695
    • Lau, G.K.1    Piratvisuth, T.2    Luo, K.X.3    Marcellin, P.4    Thongsawat, S.5    Cooksley, G.6
  • 5
    • 4544239807 scopus 로고    scopus 로고
    • Peginterferon alfa-2a alone, lamivudine alone, and the two in combination in patients with HBeAg negative chronic hepatitis B
    • Marcellin P, Lau GK, Bonino F, Farci P, Hadziyanhis S, Jin R, et al. Peginterferon alfa-2a alone, lamivudine alone, and the two in combination in patients with HBeAg negative chronic hepatitis B. N Engl J Med 2004; 351:1206-17.
    • (2004) N Engl J Med , vol.351 , pp. 1206-1217
    • Marcellin, P.1    Lau, G.K.2    Bonino, F.3    Farci, P.4    Hadziyanhis, S.5    Jin, R.6
  • 7
    • 0037468421 scopus 로고    scopus 로고
    • Adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B
    • Marcellin P, Chang TT, Lim SG, Tong MJ, Sievert W, Shiffman ML, et al. Adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B. N Engl J Med 2003; 348:808-16.
    • (2003) N Engl J Med , vol.348 , pp. 808-816
    • Marcellin, P.1    Chang, T.T.2    Lim, S.G.3    Tong, M.J.4    Sievert, W.5    Shiffman, M.L.6
  • 8
    • 33644818518 scopus 로고    scopus 로고
    • A comparison of entecavir and lamivudine for HBeAg-positive chronic hepatitis B
    • Chang TT, Gish RG, de Man R, Gadano A, Sollano J, Chao YC, et al. A comparison of entecavir and lamivudine for HBeAg-positive chronic hepatitis B. N Engl J Med 2006; 354:1001-10.
    • (2006) N Engl J Med , vol.354 , pp. 1001-1010
    • Chang, T.T.1    Gish, R.G.2    de Man, R.3    Gadano, A.4    Sollano, J.5    Chao, Y.C.6
  • 9
    • 33748541588 scopus 로고    scopus 로고
    • Novel anti-hepatitis B agents: A focus on telbivudine
    • Jones R, Nelson M. Novel anti-hepatitis B agents: A focus on telbivudine. Int J Clin Pract 2006; 60:1295-9.
    • (2006) Int J Clin Pract , vol.60 , pp. 1295-1299
    • Jones, R.1    Nelson, M.2
  • 10
    • 33646438502 scopus 로고    scopus 로고
    • Randomized, double-blind study of emtricitabine (FTC) plus clevudine versus FTC alone in treatment of chronic hepatitis B
    • Lim SG, Krastev Z, Ng TM, Mechkov G, Kotzev IA, Chan S, et al. Randomized, double-blind study of emtricitabine (FTC) plus clevudine versus FTC alone in treatment of chronic hepatitis B. Antimicrob Agents Chemother. 2006; 50: 1642-8.
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 1642-1648
    • Lim, S.G.1    Krastev, Z.2    Ng, T.M.3    Mechkov, G.4    Kotzev, I.A.5    Chan, S.6
  • 11
    • 1842291578 scopus 로고    scopus 로고
    • The treatment of chronic viral hepatitis
    • Hoofnagle, J. H., Di Bisceglie A. M. The treatment of chronic viral hepatitis. N. Engl. J. Med 1997; 336:347-56.
    • (1997) N. Engl. J. Med , vol.336 , pp. 347-356
    • Hoofnagle, J.H.1    Di Bisceglie, A.M.2
  • 12
    • 0347928672 scopus 로고    scopus 로고
    • Inhibition of hepatitis B virus replication by drug-induced depletion of nucleocapsids
    • Deres K Schroder CH Paessens A Goldmann S Hacker HJ Weber O et al. Inhibition of hepatitis B virus replication by drug-induced depletion of nucleocapsids. Science 2003; 299:893-6.
    • (2003) Science , vol.299 , pp. 893-896
    • Deres, K.1    Schroder, C.H.2    Paessens, A.3    Goldmann, S.4    Hacker, H.J.5    Weber, O.6
  • 13
    • 0036227850 scopus 로고    scopus 로고
    • Inhibition of human hepatitis B virus (HBV) by a novel non-nucleosidic compound in a transgenic mouse model
    • Weber O, Schlemmer KH, Hartmann E, Hagelschuer I, Paessens A, Graef. E, et al. Inhibition of human hepatitis B virus (HBV) by a novel non-nucleosidic compound in a transgenic mouse model. Antiviral Res 2002; 54: 69-78.
    • (2002) Antiviral Res , vol.54 , pp. 69-78
    • Weber, O.1    Schlemmer, K.H.2    Hartmann, E.3    Hagelschuer, I.4    Paessens, A.5    Graef, E.6
  • 15
    • 33845868485 scopus 로고    scopus 로고
    • BAY 41-4109 has multiple effects on Hepatitis B virus capsid assembly
    • Stray SJ, Zlotnick A.BAY 41-4109 has multiple effects on Hepatitis B virus capsid assembly. J Mol Recognit. 2006; 19: 542-8.
    • (2006) J Mol Recognit , vol.19 , pp. 542-548
    • Stray, S.J.1    Zlotnick, A.2
  • 16
    • 0026058540 scopus 로고
    • Inhibition of the replication of hepatitis B virus in vitro by 2′,3′- dideoxy-3′-thiacytidine and related analogues
    • Doong SL, Tsai CH, Schinazi RF, Liotta DC, Cheng YC. Inhibition of the replication of hepatitis B virus in vitro by 2′,3′- dideoxy-3′-thiacytidine and related analogues. Proc Natl Acad Sci USA 1991; 88:8495-9
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 8495-8499
    • Doong, S.L.1    Tsai, C.H.2    Schinazi, R.F.3    Liotta, D.C.4    Cheng, Y.C.5
  • 17
    • 0036242046 scopus 로고    scopus 로고
    • A Small Molecule Inhibits and Misdirects Assembly of Hepatitis B Virus Capsids
    • Adam Zlotnick, Pablo Ceres, Sushmita Singh, and Jennifer M. Johnson. A Small Molecule Inhibits and Misdirects Assembly of Hepatitis B Virus Capsids. J Virol 2002; 76: 4848-54
    • (2002) J Virol , vol.76 , pp. 4848-4854
    • Zlotnick, A.1    Ceres, P.2    Singh, S.3    Johnson, J.M.4
  • 18
    • 22244456417 scopus 로고    scopus 로고
    • Interferon prevents formation of replication-competent hepatitis B virus RNA-containing nucleocapsids
    • Wieland SF, Eustaquio A, Whitten-Bauer C, Boyd B, Chisari FV. Interferon prevents formation of replication-competent hepatitis B virus RNA-containing nucleocapsids. Proc Natl Acad Sci USA. 2005 28:9913-7.
    • (2005) Proc Natl Acad Sci USA , vol.28 , pp. 9913-9917
    • Wieland, S.F.1    Eustaquio, A.2    Whitten-Bauer, C.3    Boyd, B.4    Chisari, F.V.5
  • 19
    • 33947530311 scopus 로고    scopus 로고
    • Novel approaches towards conquering hepatitis B virus infection
    • Wu GY, Chen HS. Novel approaches towards conquering hepatitis B virus infection. World J Gastroenterol. 2007; 6:830-6.
    • (2007) World J Gastroenterol , vol.6 , pp. 830-836
    • Wu, G.Y.1    Chen, H.S.2
  • 20
    • 33644537402 scopus 로고    scopus 로고
    • Novel approaches to new therapies for hepatitis B virus infection
    • Loomba R, Liang TJ. Novel approaches to new therapies for hepatitis B virus infection. Antivir Ther 2006; 11:1-15.
    • (2006) Antivir Ther , vol.11 , pp. 1-15
    • Loomba, R.1    Liang, T.J.2
  • 21
    • 1842409555 scopus 로고    scopus 로고
    • Determination of the fold of the core protein of hepatitis B virus by electron cryomicroscopy
    • Bottcher B,Wynne SA,Crowther RA. Determination of the fold of the core protein of hepatitis B virus by electron cryomicroscopy. Nature 1997; 386: 88-91.
    • (1997) Nature , vol.386 , pp. 88-91
    • Bottcher, B.1    Wynne, S.A.2    Crowther, R.A.3
  • 22
    • 0036500146 scopus 로고    scopus 로고
    • The morphogenic linker peptide of HBV capsid protein forms a mobile array on the interior surface
    • Watts NR, Conway JF, Cheng N, Stahl SJ, Belnap DM, Steven AC, et al. The morphogenic linker peptide of HBV capsid protein forms a mobile array on the interior surface. EMBO J 2002; 21:876-84.
    • (2002) EMBO J , vol.21 , pp. 876-884
    • Watts, N.R.1    Conway, J.F.2    Cheng, N.3    Stahl, S.J.4    Belnap, D.M.5    Steven, A.C.6
  • 23
    • 0038290377 scopus 로고    scopus 로고
    • New enzyme immunoassay for detection of hepatitis B virus core antigen (HBcAg) and Relation between Levels of HBcAg and HBV DNA
    • Kimura T, Rokuhara A, Matsumoto A, Yagi S, Tanaka E, Kiyosawa K, et al. New enzyme immunoassay for detection of hepatitis B virus core antigen (HBcAg) and Relation between Levels of HBcAg and HBV DNA. J Clin Microbiol 2003; 41:1901-6.
    • (2003) J Clin Microbiol , vol.41 , pp. 1901-1906
    • Kimura, T.1    Rokuhara, A.2    Matsumoto, A.3    Yagi, S.4    Tanaka, E.5    Kiyosawa, K.6
  • 25
    • 0037382795 scopus 로고    scopus 로고
    • Inhibition of hepatitis B virus expression and replication by RNA interference
    • Sholomai A,Shaul Y. Inhibition of hepatitis B virus expression and replication by RNA interference. Hepatology 2003; 37: 764-70.
    • (2003) Hepatology , vol.37 , pp. 764-770
    • Sholomai, A.1    Shaul, Y.2
  • 26
    • 27244440960 scopus 로고    scopus 로고
    • Inhibition of hepatitis. B virus gene expression and replication by helioxanthin and its derivative
    • Li Y, Fu L, Yeo H, Zhu JL, Chou CK, Kou YH, et al. Inhibition of hepatitis. B virus gene expression and replication by helioxanthin and its derivative. Antivir Chem Chemother 2005; 16:193-201.
    • (2005) Antivir Chem Chemother , vol.16 , pp. 193-201
    • Li, Y.1    Fu, L.2    Yeo, H.3    Zhu, J.L.4    Chou, C.K.5    Kou, Y.H.6
  • 27
    • 0142151773 scopus 로고    scopus 로고
    • Exploring the biological basis of hepatitis B e antigen in hepatitis B virus infection
    • Milich D, Liang TJ. Exploring the biological basis of hepatitis B e antigen in hepatitis B virus infection. Hepatology. 2003; 38:1075-86.
    • (2003) Hepatology , vol.38 , pp. 1075-1086
    • Milich, D.1    Liang, T.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.