Aberrant repair initiated by mismatch-specific thymine-DNA glycosylases provides a mechanism for the mutational bias observed in CpG islands

Nucleic Acids Research

Volumn 42, Issue 10, 2014, Pages 6300-6313

  Talhaoui, Ibtissam ^a   Couve, Sophie ^b   Gros, Laurent ^a,c   Ishchenko, Alexander A ^a   Matkarimov, Bakhyt ^d   Saparbaev, Murat K ^a  

^a INSTITUT GUSTAVE ROUSSY   (France)

^b PSL RESEARCH UNIVERSITY   (France)

^c AB Science SA   (France)

^d NAZARBAYEV UNIVERSITY   (Kazakhstan)

Author keywords

[No Author keywords available]

Indexed keywords

1,N6 ETHENOADENINE; 8 OXOADENINE; ADENINE; ADENINE DERIVATIVE; HYPOXANTHINE; OLIGONUCLEOTIDE; THYMINE DNA GLYCOSYLASE; UNCLASSIFIED DRUG;

ARTICLE; BASE MISPAIRING; CATALYSIS; CONTROLLED STUDY; CPG ISLAND; DNA DAMAGE; DNA REPAIR; DNA STRAND; EXCISION REPAIR; GENE TARGETING; IN VITRO STUDY; MUTATION RATE; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM;

ADENINE; ANIMALS; BASE PAIR MISMATCH; CELLS, CULTURED; CPG ISLANDS; DNA; DNA DAMAGE; DNA REPAIR; HUMANS; MICE; MUTATION; OLIGONUCLEOTIDES; POLYMORPHISM, SINGLE NUCLEOTIDE; THYMINE; THYMINE DNA GLYCOSYLASE;

EID: 84903200325     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gku246     Document Type: Article

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