-
1
-
-
0037174635
-
Treatment of ischemic brain damage by perturbing NMDA receptor-PSD-95 protein interactions
-
DOI 10.1126/science.1072873
-
Aarts M., Liu Y., Liu L., Besshoh S., Arundine M., Gurd J. W., Wang Y. T., Salter M. W., and, Tymianski M., (2002) Treatment of ischemic brain damage by perturbing NMDA receptor- PSD-95 protein interactions. Science 298, 846-850. (Pubitemid 35231541)
-
(2002)
Science
, vol.298
, Issue.5594
, pp. 846-850
-
-
Aarts, M.1
Liu, Y.2
Liu, L.3
Besshoh, S.4
Arundine, M.5
Gurd, J.W.6
Wang, Y.-T.7
Salter, M.W.8
Tymianski, M.9
-
2
-
-
0042536473
-
Molecular mechanisms of calcium-dependent neurodegeneration in excitotoxicity
-
DOI 10.1016/S0143-4160(03)00141-6
-
Arundine M., and, Tymianski M., (2003) Molecular mechanisms of calcium-dependent neurodegeneration in excitotoxicity. Cell Calcium 34, 325-337. (Pubitemid 37021228)
-
(2003)
Cell Calcium
, vol.34
, Issue.4-5
, pp. 325-337
-
-
Arundine, M.1
Tymianski, M.2
-
3
-
-
0033591228
-
Adaptor proteins Grb2 and Crk couple Pyk2 with activation of specific mitogen-activated protein kinase cascades
-
Blaukat A., Ivankovic-Dikic I., Gronroos E., Dolfi F., Tokiwa G., Vuori K., and, Dikic I., (1999) Adaptor proteins Grb2 and Crk couple Pyk2 with activation of specific mitogen-activated protein kinase cascades. J. Biol. Chem. 274, 14893-14901.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 14893-14901
-
-
Blaukat, A.1
Ivankovic-Dikic, I.2
Gronroos, E.3
Dolfi, F.4
Tokiwa, G.5
Vuori, K.6
Dikic, I.7
-
4
-
-
33746366493
-
Synaptic plasticity: One STEP at a time
-
DOI 10.1016/j.tins.2006.06.007, PII S0166223606001214
-
Braithwaite S. P., Paul S., Nairn A. C., and, Lombroso P. J., (2006) Synaptic plasticity: one STEP at a time. Trends Neurosci. 29, 452-458. (Pubitemid 44118442)
-
(2006)
Trends in Neurosciences
, vol.29
, Issue.8
, pp. 452-458
-
-
Braithwaite, S.P.1
Paul, S.2
Nairn, A.C.3
Lombroso, P.J.4
-
5
-
-
42549114708
-
Expression and function of striatal enriched protein tyrosine phosphatase is profoundly altered in cerebral ischemia
-
DOI 10.1111/j.1460-9568.2008.06209.x
-
Braithwaite S. P., Xu J., Leung J., Urfer R., Nikolich K., Oksenberg D., Lombroso P. J., and, Shamloo M., (2008) Expression and function of striatal enriched protein tyrosine phosphatase is profoundly altered in cerebral ischemia. Eur. J. Neurosci. 27, 2444-2452. (Pubitemid 351590917)
-
(2008)
European Journal of Neuroscience
, vol.27
, Issue.9
, pp. 2444-2452
-
-
Braithwaite, S.P.1
Xu, J.2
Leung, J.3
Urfer, R.4
Nikolich, K.5
Oksenberg, D.6
Lombroso, P.J.7
Shamloo, M.8
-
6
-
-
12144271690
-
The PSD95-nNOS interface: A target for inhibition of excitotoxic p38 stress-activated protein kinase activation and cell death
-
DOI 10.1083/jcb.200407024
-
Cao J., Viholainen J. I., Dart C., Warwick H. K., Leyland M. L., and, Courtney M. J., (2005) The PSD95-nNOS interface: a target for inhibition of excitotoxic p38 stress-activated protein kinase activation and cell death. J. Cell Biol. 168, 117-126. (Pubitemid 40111062)
-
(2005)
Journal of Cell Biology
, vol.168
, Issue.1
, pp. 117-126
-
-
Cao, J.1
Viholainen, J.I.2
Dart, C.3
Warwick, H.K.4
Leyland, M.L.5
Courtney, M.J.6
-
7
-
-
58149373434
-
Polyglutamine-modulated striatal calpain activity in YAC transgenic huntington disease mouse model: Impact on NMDA receptor function and toxicity
-
Cowan C. M., Fan M. M., Fan J., Shehadeh J., Zhang L. Y., Graham R. K., Hayden M. R., and, Raymond L. A., (2008) Polyglutamine-modulated striatal calpain activity in YAC transgenic huntington disease mouse model: impact on NMDA receptor function and toxicity. J. Neurosci. 28, 12725-12735.
-
(2008)
J. Neurosci.
, vol.28
, pp. 12725-12735
-
-
Cowan, C.M.1
Fan, M.M.2
Fan, J.3
Shehadeh, J.4
Zhang, L.Y.5
Graham, R.K.6
Hayden, M.R.7
Raymond, L.A.8
-
8
-
-
84890027845
-
Chronic blockade of extrasynaptic NMDA receptors ameliorates synaptic dysfunction and pro-death signaling in Huntington disease transgenic mice
-
Dau A., Gladding C. M., Sepers M. D., and, Raymond L. A., (2014) Chronic blockade of extrasynaptic NMDA receptors ameliorates synaptic dysfunction and pro-death signaling in Huntington disease transgenic mice. Neurobiol. Dis. 62, 533-542.
-
(2014)
Neurobiol. Dis.
, vol.62
, pp. 533-542
-
-
Dau, A.1
Gladding, C.M.2
Sepers, M.D.3
Raymond, L.A.4
-
9
-
-
1642536318
-
Dopamine D1-Dependent Trafficking of Striatal N-Methyl-D-aspartate Glutamate Receptors Requires Fyn Protein Tyrosine Kinase but Not DARPP-32
-
DOI 10.1124/mol.65.1.121
-
Dunah A. W., Sirianni A. C., Fienberg A. A., Bastia E., Schwarzschild M. A., and, Standaert D. G., (2004) Dopamine D1-dependent trafficking of striatal N-methyl-D-aspartate glutamate receptors requires Fyn protein tyrosine kinase but not DARPP-32. Mol. Pharmacol. 65, 121-129. (Pubitemid 38113892)
-
(2004)
Molecular Pharmacology
, vol.65
, Issue.1
, pp. 121-129
-
-
Dunah, A.W.1
Sirianni, A.C.2
Fienberg, A.A.3
Bastia, E.4
Schwarzschild, M.A.5
Standaert, D.G.6
-
10
-
-
34147112751
-
Altered NMDA receptor trafficking in a yeast artificial chromosome transgenic mouse model of Huntington's disease
-
DOI 10.1523/JNEUROSCI.4356-06.2007
-
Fan M. M., Fernandes H. B., Zhang L. Y., Hayden M. R., and, Raymond L. A., (2007) Altered NMDA receptor trafficking in a yeast artificial chromosome transgenic mouse model of Huntington's disease. J. Neurosci. 27, 3768-3779. (Pubitemid 46557661)
-
(2007)
Journal of Neuroscience
, vol.27
, Issue.14
, pp. 3768-3779
-
-
Fan, M.M.Y.1
Fernandes, H.B.2
Zhang, L.Y.J.3
Hayden, M.R.4
Raymond, L.A.5
-
11
-
-
69749091508
-
Interaction of postsynaptic density protein-95 with NMDA receptors influences excitotoxicity in the yeast artificial chromosome mouse model of Huntington's disease
-
Fan J., Cowan C. M., Zhang L. Y., Hayden M. R., and, Raymond L. A., (2009) Interaction of postsynaptic density protein-95 with NMDA receptors influences excitotoxicity in the yeast artificial chromosome mouse model of Huntington's disease. J. Neurosci. 29, 10928-10938.
-
(2009)
J. Neurosci.
, vol.29
, pp. 10928-10938
-
-
Fan, J.1
Cowan, C.M.2
Zhang, L.Y.3
Hayden, M.R.4
Raymond, L.A.5
-
12
-
-
84856579300
-
P38 MAPK is involved in enhanced NMDA receptor-dependent excitotoxicity in YAC transgenic mouse model of Huntington disease
-
Fan J., Gladding C. M., Wang L., Zhang L. Y., Kaufman A. M., Milnerwood A. J., and, Raymond L. A., (2012) P38 MAPK is involved in enhanced NMDA receptor-dependent excitotoxicity in YAC transgenic mouse model of Huntington disease. Neurobiol. Dis. 45, 999-1009.
-
(2012)
Neurobiol. Dis.
, vol.45
, pp. 999-1009
-
-
Fan, J.1
Gladding, C.M.2
Wang, L.3
Zhang, L.Y.4
Kaufman, A.M.5
Milnerwood, A.J.6
Raymond, L.A.7
-
13
-
-
0037096376
-
Calpain Activation in Huntington's Disease
-
Gafni J., and, Ellerby L. M., (2002) Calpain activation in Huntington's disease. J. Neurosci. 22, 4842-4849. (Pubitemid 37465599)
-
(2002)
Journal of Neuroscience
, vol.22
, Issue.12
, pp. 4842-4849
-
-
Gafni, J.1
Ellerby, L.M.2
-
14
-
-
0034710303
-
P38 MAP kinase mediates Bax translocation in nitric oxide-induced apoptosis in neurons
-
DOI 10.1083/jcb.150.2.335
-
Ghatan S., Larner S., Kinoshita Y., Hetman M., Patel L., Xia Z., Youle R. J., and, Morrison R. S., (2000) p38 MAP kinase mediates bax translocation in nitric oxide-induced apoptosis in neurons. J. Cell Biol. 150, 335-347. (Pubitemid 30491357)
-
(2000)
Journal of Cell Biology
, vol.150
, Issue.2
, pp. 335-347
-
-
Ghatan, S.1
Larner, S.2
Kinoshita, Y.3
Hetman, M.4
Patel, L.5
Xia, Z.6
Youle, R.J.7
Morrison, R.S.8
-
15
-
-
79961168563
-
Mechanisms underlying NMDA receptor synaptic/extrasynaptic distribution and function
-
Gladding C. M., and, Raymond L. A., (2011) Mechanisms underlying NMDA receptor synaptic/extrasynaptic distribution and function. Mol. Cell. Neurosci. 48, 308-320.
-
(2011)
Mol. Cell. Neurosci.
, vol.48
, pp. 308-320
-
-
Gladding, C.M.1
Raymond, L.A.2
-
16
-
-
84865078592
-
Calpain and STriatal-Enriched protein tyrosine phosphatase (STEP) activation contribute to extrasynaptic NMDA receptor localization in a Huntington's disease mouse model
-
Gladding C. M., Sepers M. D., Xu J., Zhang L. Y., Milnerwood A. J., Lombroso P. J., and, Raymond L. A., (2012) Calpain and STriatal-Enriched protein tyrosine phosphatase (STEP) activation contribute to extrasynaptic NMDA receptor localization in a Huntington's disease mouse model. Hum. Mol. Genet. 21, 3739-3752.
-
(2012)
Hum. Mol. Genet.
, vol.21
, pp. 3739-3752
-
-
Gladding, C.M.1
Sepers, M.D.2
Xu, J.3
Zhang, L.Y.4
Milnerwood, A.J.5
Lombroso, P.J.6
Raymond, L.A.7
-
17
-
-
60349088785
-
Phospho-regulation of synaptic and extrasynaptic N-methyl-d-aspartate receptors in adult hippocampal slices
-
Goebel-Goody S. M., Davies K. D., Alvestad Linger R. M., Freund R. K., and, Browning M. D., (2009) Phospho-regulation of synaptic and extrasynaptic N-methyl-d-aspartate receptors in adult hippocampal slices. Neuroscience 158, 1446-1459.
-
(2009)
Neuroscience
, vol.158
, pp. 1446-1459
-
-
Goebel-Goody, S.M.1
Davies, K.D.2
Alvestad Linger, R.M.3
Freund, R.K.4
Browning, M.D.5
-
18
-
-
33847109840
-
Reactive oxygen species and p38 mitogen-activated protein kinase activate bax to induce mitochondrial cytochrome c release and apoptosis in response to malonate
-
DOI 10.1124/mol.106.030718
-
Gomez-Lazaro M., Galindo M. F., Melero-Fernandez de Mera R. M., Fernandez-Gomez F. J., Concannon C. G., Segura M. F., Comella J. X., Prehn J. H., and, Jordan J., (2007) Reactive oxygen species and p38 mitogen-activated protein kinase activate Bax to induce mitochondrial cytochrome c release and apoptosis in response to malonate. Mol. Pharmacol. 71, 736-743. (Pubitemid 46294084)
-
(2007)
Molecular Pharmacology
, vol.71
, Issue.3
, pp. 736-743
-
-
Gomez-Lazaro, M.1
Galindo, M.F.2
Melero-Fernandez De Mera, R.M.3
Fernandez-Gomez, F.J.4
Concannon, C.G.5
Segura, M.F.6
Comella, J.X.7
Prehn, J.H.M.8
Jordan, J.9
-
19
-
-
60849093185
-
Differential susceptibility to excitotoxic stress in YAC128 mouse models of Huntington disease between initiation and progression of disease
-
Graham R. K., Pouladi M. A., Joshi P., et al,. (2009) Differential susceptibility to excitotoxic stress in YAC128 mouse models of Huntington disease between initiation and progression of disease. J. Neurosci. 29, 2193-2204.
-
(2009)
J. Neurosci.
, vol.29
, pp. 2193-2204
-
-
Graham, R.K.1
Pouladi, M.A.2
Joshi, P.3
-
20
-
-
0036241207
-
Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways
-
DOI 10.1038/nn835
-
Hardingham G. E., Fukunaga Y., and, Bading H., (2002) Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways. Nat. Neurosci. 5, 405-414. (Pubitemid 34454245)
-
(2002)
Nature Neuroscience
, vol.5
, Issue.5
, pp. 405-414
-
-
Hardingham, G.E.1
Fukunaga, Y.2
Bading, H.3
-
21
-
-
0027480960
-
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group
-
HDCRG
-
HDCRG (1993) A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group. Cell 72, 971-983.
-
(1993)
Cell
, vol.72
, pp. 971-983
-
-
-
22
-
-
80053231513
-
Developmental localization of NMDA receptors, Src and MAP kinases in mouse brain
-
Jiang X., Knox R., Pathipati P., and, Ferriero D., (2011) Developmental localization of NMDA receptors, Src and MAP kinases in mouse brain. Neurosci. Lett. 503, 215-219.
-
(2011)
Neurosci. Lett.
, vol.503
, pp. 215-219
-
-
Jiang, X.1
Knox, R.2
Pathipati, P.3
Ferriero, D.4
-
23
-
-
84871541961
-
A common STEP in the synaptic pathology of diverse neuropsychiatric disorders
-
Johnson M. A., and, Lombroso P. J., (2012) A common STEP in the synaptic pathology of diverse neuropsychiatric disorders. Yale J. Biol. Med. 85, 481-490.
-
(2012)
Yale J. Biol. Med.
, vol.85
, pp. 481-490
-
-
Johnson, M.A.1
Lombroso, P.J.2
-
24
-
-
0035940412
-
Caspase 3-cleaved N-terminal fragments of wild-type and mutant huntingtin are present in normal and Huntington's disease brains, associate with membranes, and undergo calpaindependent proteolysis
-
DOI 10.1073/pnas.221451398
-
Kim Y. J., Yi Y., Sapp E., Wang Y., Cuiffo B., Kegel K. B., Qin Z. H., Aronin N., and, DiFiglia M., (2001) Caspase 3-cleaved N-terminal fragments of wild-type and mutant huntingtin are present in normal and Huntington's disease brains, associate with membranes, and undergo calpain-dependent proteolysis. Proc. Natl Acad. Sci. USA 98, 12784-12789. (Pubitemid 33020022)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.22
, pp. 12784-12789
-
-
Kim, Y.J.1
Yi, Y.2
Sapp, E.3
Wang, Y.4
Cuiffo, B.5
Kegel, K.B.6
Qin, Z.-H.7
Aronin, N.8
DiFiglia, M.9
-
25
-
-
34249099711
-
NMDA receptor trafficking in synaptic plasticity and neuropsychiatric disorders
-
DOI 10.1038/nrn2153, PII NRN2153
-
Lau C. G., and, Zukin R. S., (2007) NMDA receptor trafficking in synaptic plasticity and neuropsychiatric disorders. Nat. Rev. Neurosci. 8, 413-426. (Pubitemid 46789232)
-
(2007)
Nature Reviews Neuroscience
, vol.8
, Issue.6
, pp. 413-426
-
-
Lau, C.G.1
Zukin, R.S.2
-
26
-
-
0029154733
-
Protein tyrosine kinase PYK2 involved in Ca(2 +)-induced regulation of ion channel and MAP kinase functions
-
Lev S., Moreno H., Martinez R., Canoll P., Peles E., Musacchio J. M., Plowman G. D., Rudy B., and, Schlessinger J., (1995) Protein tyrosine kinase PYK2 involved in Ca(2 +)-induced regulation of ion channel and MAP kinase functions. Nature 376, 737-745.
-
(1995)
Nature
, vol.376
, pp. 737-745
-
-
Lev, S.1
Moreno, H.2
Martinez, R.3
Canoll, P.4
Peles, E.5
Musacchio, J.M.6
Plowman, G.D.7
Rudy, B.8
Schlessinger, J.9
-
27
-
-
57349135887
-
Neuronal viability is controlled by a functional relation between synaptic and extrasynaptic NMDA receptors
-
Leveille F., El Gaamouch F., Gouix E., Lecocq M., Lobner D., Nicole O., and, Buisson A., (2008) Neuronal viability is controlled by a functional relation between synaptic and extrasynaptic NMDA receptors. FASEB J. 22, 4258-4271.
-
(2008)
FASEB J.
, vol.22
, pp. 4258-4271
-
-
Leveille, F.1
El Gaamouch, F.2
Gouix, E.3
Lecocq, M.4
Lobner, D.5
Nicole, O.6
Buisson, A.7
-
28
-
-
14844314896
-
Enhanced striatal NR2B-containing N-methyl-D-aspartate receptor-mediated synaptic currents in a mouse model of Huntington disease
-
DOI 10.1152/jn.00308.2004
-
Li L., Murphy T. H., Hayden M. R., and, Raymond L. A., (2004) Enhanced striatal NR2B-containing N-methyl-D-aspartate receptor-mediated synaptic currents in a mouse model of Huntington disease. J. Neurophysiol. 92, 2738-2746. (Pubitemid 40340486)
-
(2004)
Journal of Neurophysiology
, vol.92
, Issue.5
, pp. 2738-2746
-
-
Li, L.1
Murphy, T.H.2
Hayden, M.R.3
Raymond, L.A.4
-
29
-
-
0001583878
-
Activation of MLK2-mediated signaling cascades by polyglutamine-expanded huntingtin
-
DOI 10.1074/jbc.C000180200
-
Liu Y. F., Dorow D., and, Marshall J., (2000) Activation of MLK2-mediated signaling cascades by polyglutamine-expanded huntingtin. J. Biol. Chem. 275, 19035-19040. (Pubitemid 30422870)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.25
, pp. 19035-19040
-
-
Liu, Y.F.1
Dorow, D.2
Marshall, J.3
-
30
-
-
74549181538
-
Early increase in extrasynaptic NMDA receptor signaling and expression contributes to phenotype onset in Huntington's disease mice
-
Milnerwood A. J., Gladding C. M., Pouladi M. A., et al,. (2010) Early increase in extrasynaptic NMDA receptor signaling and expression contributes to phenotype onset in Huntington's disease mice. Neuron 65, 178-190.
-
(2010)
Neuron
, vol.65
, pp. 178-190
-
-
Milnerwood, A.J.1
Gladding, C.M.2
Pouladi, M.A.3
-
31
-
-
0037025303
-
Striatal enriched phosphatase 61 dephosphorylates Fyn at phosphotyrosine 420
-
DOI 10.1074/jbc.M111683200
-
Nguyen T. H., Liu J., and, Lombroso P. J., (2002) Striatal enriched phosphatase 61 dephosphorylates Fyn at phosphotyrosine 420. J. Biol. Chem. 277, 24274-24279. (Pubitemid 34951945)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.27
, pp. 24274-24279
-
-
Nguyen, T.-H.1
Liu, J.2
Lombroso, P.J.3
-
32
-
-
59149102054
-
Neuronal pentraxins modulate cocaine-induced neuroadaptations
-
Pacchioni A. M., Vallone J., Worley P. F., and, Kalivas P. W., (2009) Neuronal pentraxins modulate cocaine-induced neuroadaptations. J. Pharmacol. Exp. Ther. 328, 183-192.
-
(2009)
J. Pharmacol. Exp. Ther.
, vol.328
, pp. 183-192
-
-
Pacchioni, A.M.1
Vallone, J.2
Worley, P.F.3
Kalivas, P.W.4
-
33
-
-
0034255148
-
The dopamine/D1 receptor mediates the phosphorylation and inactivation of the protein tyrosine phosphatase STEP via a PKA-dependent pathway
-
Paul S., Snyder G. L., Yokakura H., Picciotto M. R., Nairn A. C., and, Lombroso P. J., (2000) The Dopamine/D1 receptor mediates the phosphorylation and inactivation of the protein tyrosine phosphatase STEP via a PKA-dependent pathway. J. Neurosci. 20, 5630-5638. (Pubitemid 30636889)
-
(2000)
Journal of Neuroscience
, vol.20
, Issue.15
, pp. 5630-5638
-
-
Paul, S.1
Snyder, G.L.2
Yokakura, H.3
Picciotto, M.R.4
Nairn, A.C.5
Lombroso, P.J.6
-
34
-
-
0037220735
-
NMDA-mediated activation of the tyrosine phosphatase STEP regulates the duration of ERK signaling
-
DOI 10.1038/nn989
-
Paul S., Nairn A. C., Wang P., and, Lombroso P. J., (2003) NMDA-mediated activation of the tyrosine phosphatase STEP regulates the duration of ERK signaling. Nat. Neurosci. 6, 34-42. (Pubitemid 36026330)
-
(2003)
Nature Neuroscience
, vol.6
, Issue.1
, pp. 34-42
-
-
Paul, S.1
Nairn, A.C.2
Wang, P.3
Lombroso, P.J.4
-
35
-
-
78649994240
-
NR2B-NMDA receptor mediated modulation of the tyrosine phosphatase STEP regulates glutamate induced neuronal cell death
-
Poddar R., Deb I., Mukherjee S., and, Paul S., (2010) NR2B-NMDA receptor mediated modulation of the tyrosine phosphatase STEP regulates glutamate induced neuronal cell death. J. Neurochem. 115, 1350-1362.
-
(2010)
J. Neurochem.
, vol.115
, pp. 1350-1362
-
-
Poddar, R.1
Deb, I.2
Mukherjee, S.3
Paul, S.4
-
36
-
-
33645217296
-
SynGAP regulates synaptic strength and mitogen-activated protein kinases in cultured neurons
-
Rumbaugh G., Adams J. P., Kim J. H., and, Huganir R. L., (2006) SynGAP regulates synaptic strength and mitogen-activated protein kinases in cultured neurons. Proc. Natl Acad. Sci. USA 103, 4344-4351.
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 4344-4351
-
-
Rumbaugh, G.1
Adams, J.P.2
Kim, J.H.3
Huganir, R.L.4
-
37
-
-
79958054247
-
Striatal-enriched protein tyrosine phosphatase expression and activity in Huntington's disease: A STEP in the resistance to excitotoxicity
-
Saavedra A., Giralt A., Rue L., et al,. (2011) Striatal-enriched protein tyrosine phosphatase expression and activity in Huntington's disease: a STEP in the resistance to excitotoxicity. J. Neurosci. 31, 8150-8162.
-
(2011)
J. Neurosci.
, vol.31
, pp. 8150-8162
-
-
Saavedra, A.1
Giralt, A.2
Rue, L.3
-
38
-
-
30744437894
-
Striatal neuronal apoptosis is preferentially enhanced by NMDA receptor activation in YAC transgenic mouse model of Huntington disease
-
DOI 10.1016/j.nbd.2005.08.001, PII S0969996105002172
-
Shehadeh J., Fernandes H. B., Zeron Mullins M. M., Graham R. K., Leavitt B. R., Hayden M. R., and, Raymond L. A., (2006) Striatal neuronal apoptosis is preferentially enhanced by NMDA receptor activation in YAC transgenic mouse model of Huntington disease. Neurobiol. Dis. 21, 392-403. (Pubitemid 43099862)
-
(2006)
Neurobiology of Disease
, vol.21
, Issue.2
, pp. 392-403
-
-
Shehadeh, J.1
Fernandes, H.B.2
Zeron Mullins, M.M.3
Graham, R.K.4
Leavitt, B.R.5
Hayden, M.R.6
Raymond, L.A.7
-
39
-
-
54849439830
-
Specific targeting of pro-death NMDA receptor signals with differing reliance on the NR2B PDZ ligand
-
Soriano F. X., Martel M. A., Papadia S., et al,. (2008) Specific targeting of pro-death NMDA receptor signals with differing reliance on the NR2B PDZ ligand. J. Neurosci. 28, 10696-10710.
-
(2008)
J. Neurosci.
, vol.28
, pp. 10696-10710
-
-
Soriano, F.X.1
Martel, M.A.2
Papadia, S.3
-
40
-
-
67651172947
-
Extrasynaptic NMDA receptors couple preferentially to excitotoxicity via calpain-mediated cleavage of STEP
-
Xu J., Kurup P., Zhang Y., Goebel-Goody S. M., Wu P. H., Hawasli A. H., Baum M. L., Bibb J. A., and, Lombroso P. J., (2009) Extrasynaptic NMDA receptors couple preferentially to excitotoxicity via calpain-mediated cleavage of STEP. J. Neurosci. 29, 9330-9343.
-
(2009)
J. Neurosci.
, vol.29
, pp. 9330-9343
-
-
Xu, J.1
Kurup, P.2
Zhang, Y.3
Goebel-Goody, S.M.4
Wu, P.H.5
Hawasli, A.H.6
Baum, M.L.7
Bibb, J.A.8
Lombroso, P.J.9
-
41
-
-
84862296991
-
Striatal-enriched protein-tyrosine phosphatase (STEP) regulates Pyk2 kinase activity
-
Xu J., Kurup P., Bartos J. A., Patriarchi T., Hell J. W., and, Lombroso P. J., (2012) Striatal-enriched protein-tyrosine phosphatase (STEP) regulates Pyk2 kinase activity. J. Biol. Chem. 287, 20942-20956.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 20942-20956
-
-
Xu, J.1
Kurup, P.2
Bartos, J.A.3
Patriarchi, T.4
Hell, J.W.5
Lombroso, P.J.6
-
42
-
-
0037075624
-
Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease
-
DOI 10.1016/S0896-6273(02)00615-3
-
Zeron M. M., Hansson O., Chen N., Wellington C. L., Leavitt B. R., Brundin P., Hayden M. R., and, Raymond L. A., (2002) Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease. Neuron 33, 849-860. (Pubitemid 34246352)
-
(2002)
Neuron
, vol.33
, Issue.6
, pp. 849-860
-
-
Zeron, M.M.1
Hansson, O.2
Chen, N.3
Wellington, C.L.4
Leavitt, B.R.5
Brundin, P.6
Hayden, M.R.7
Raymond, L.A.8
|