-
1
-
-
0027476024
-
A synaptic model of memory: long-term potentiation in the hippocampus
-
Bliss, T.V. and Collingridge, G.L. (1993) A synaptic model of memory: long-term potentiation in the hippocampus. Nature, 361, 31-39.
-
(1993)
Nature
, vol.361
, pp. 31-39
-
-
Bliss, T.V.1
Collingridge, G.L.2
-
2
-
-
0042536473
-
Molecular mechanisms of calcium-dependent neurodegeneration in excitotoxicity
-
Arundine, M. and Tymianski, M. (2003) Molecular mechanisms of calcium-dependent neurodegeneration in excitotoxicity. Cell Calcium, 34, 325-337.
-
(2003)
Cell Calcium
, vol.34
, pp. 325-337
-
-
Arundine, M.1
Tymianski, M.2
-
3
-
-
79961168563
-
Mechanisms underlying NMDA receptor synaptic/extrasynaptic distribution and function
-
Gladding, C.M. and Raymond, L.A. (2011) Mechanisms underlying NMDA receptor synaptic/extrasynaptic distribution and function. Mol. Cell Neurosci, 48, 308-320.
-
(2011)
Mol. Cell Neurosci
, vol.48
, pp. 308-320
-
-
Gladding, C.M.1
Raymond, L.A.2
-
4
-
-
34249099711
-
NMDA receptor trafficking in synaptic plasticity and neuropsychiatric disorders
-
Lau, C.G. and Zukin, R.S. (2007) NMDA receptor trafficking in synaptic plasticity and neuropsychiatric disorders. Nat. Rev. Neurosci., 8, 413-426.
-
(2007)
Nat. Rev. Neurosci.
, vol.8
, pp. 413-426
-
-
Lau, C.G.1
Zukin, R.S.2
-
5
-
-
0021982117
-
Evidence for degenerative and regenerative changes in neostriatal spiny neurons in Huntington's disease
-
Graveland, G.A., Williams, R.S. and DiFiglia, M. (1985) Evidence for degenerative and regenerative changes in neostriatal spiny neurons in Huntington's disease. Science, 227, 770-773.
-
(1985)
Science
, vol.227
, pp. 770-773
-
-
Graveland, G.A.1
Williams, R.S.2
DiFiglia, M.3
-
6
-
-
0027480960
-
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
-
HDCRG
-
HDCRG (1993) A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell, 72, 971-983.
-
(1993)
Cell
, vol.72
, pp. 971-983
-
-
-
7
-
-
0035889535
-
NMDA receptor function in mouse models of Huntington disease
-
Cepeda, C., Ariano, M.A., Calvert, C.R., Flores-Hernandez, J., Chandler, S.H., Leavitt, B.R., Hayden, M.R. and Levine, M.S. (2001) NMDA receptor function in mouse models of Huntington disease. J. Neurosci. Res., 66, 525-539.
-
(2001)
J. Neurosci. Res.
, vol.66
, pp. 525-539
-
-
Cepeda, C.1
Ariano, M.A.2
Calvert, C.R.3
Flores-Hernandez, J.4
Chandler, S.H.5
Leavitt, B.R.6
Hayden, M.R.7
Levine, M.S.8
-
8
-
-
34147112751
-
Altered NMDA receptor trafficking in a yeast artificial chromosome transgenic mouse model of Huntington's disease
-
Fan, M.M., Fernandes, H.B., Zhang, L.Y., Hayden, M.R. and Raymond, L.A. (2007) Altered NMDA receptor trafficking in a yeast artificial chromosome transgenic mouse model of Huntington's disease. J. Neurosci., 27, 3768-3779.
-
(2007)
J. Neurosci.
, vol.27
, pp. 3768-3779
-
-
Fan, M.M.1
Fernandes, H.B.2
Zhang, L.Y.3
Hayden, M.R.4
Raymond, L.A.5
-
9
-
-
60849093185
-
Differential susceptibility to excitotoxic stress in YAC128 mouse models of Huntington disease between initiation and progression of disease
-
Graham, R.K., Pouladi, M.A., Joshi, P., Lu, G., Deng, Y., Wu, N.P., Figueroa, B.E., Metzler, M., Andre, V.M., Slow, E.J. et al. (2009) Differential susceptibility to excitotoxic stress in YAC128 mouse models of Huntington disease between initiation and progression of disease. J. Neurosci., 29, 2193-2204.
-
(2009)
J. Neurosci.
, vol.29
, pp. 2193-2204
-
-
Graham, R.K.1
Pouladi, M.A.2
Joshi, P.3
Lu, G.4
Deng, Y.5
Wu, N.P.6
Figueroa, B.E.7
Metzler, M.8
Andre, V.M.9
Slow, E.J.10
-
10
-
-
14844314896
-
Enhanced striatal NR2B-containing N-methyl-D-aspartate receptor-mediated synaptic currents in a mouse model of Huntington disease
-
Li, L., Murphy, T.H., Hayden, M.R. and Raymond, L.A. (2004) Enhanced striatal NR2B-containing N-methyl-D-aspartate receptor-mediated synaptic currents in a mouse model of Huntington disease. J. Neurophysiol., 92, 2738-2746.
-
(2004)
J. Neurophysiol.
, vol.92
, pp. 2738-2746
-
-
Li, L.1
Murphy, T.H.2
Hayden, M.R.3
Raymond, L.A.4
-
11
-
-
37449011119
-
Corticostriatal synaptic function in mouse models of Huntington's disease: early effects of huntingtin repeat length and protein load
-
Milnerwood, A.J. and Raymond, L.A. (2007) Corticostriatal synaptic function in mouse models of Huntington's disease: early effects of huntingtin repeat length and protein load. J. Physiol., 585, 817-831.
-
(2007)
J. Physiol.
, vol.585
, pp. 817-831
-
-
Milnerwood, A.J.1
Raymond, L.A.2
-
12
-
-
30744437894
-
Striatal neuronal apoptosis is preferentially enhanced by NMDA receptor activation in YAC transgenic mouse model of Huntington disease
-
Shehadeh, J., Fernandes, H.B., Zeron Mullins, M.M., Graham, R.K., Leavitt, B.R., Hayden, M.R. and Raymond, L.A. (2006) Striatal neuronal apoptosis is preferentially enhanced by NMDA receptor activation in YAC transgenic mouse model of Huntington disease. Neurobiol. Dis., 21, 392-403.
-
(2006)
Neurobiol. Dis.
, vol.21
, pp. 392-403
-
-
Shehadeh, J.1
Fernandes, H.B.2
Zeron Mullins, M.M.3
Graham, R.K.4
Leavitt, B.R.5
Hayden, M.R.6
Raymond, L.A.7
-
13
-
-
14044264256
-
Disturbed Ca2+ signaling and apoptosis of medium spiny neurons in Huntington's disease
-
Tang, T.S., Slow, E., Lupu, V., Stavrovskaya, I.G., Sugimori, M., Llinas, R., Kristal, B.S., Hayden, M.R. and Bezprozvanny, I. (2005) Disturbed Ca2+ signaling and apoptosis of medium spiny neurons in Huntington's disease. Proc. Natl. Acad. Sci. USA, 102, 2602-2607.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 2602-2607
-
-
Tang, T.S.1
Slow, E.2
Lupu, V.3
Stavrovskaya, I.G.4
Sugimori, M.5
Llinas, R.6
Kristal, B.S.7
Hayden, M.R.8
Bezprozvanny, I.9
-
14
-
-
0037075624
-
Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease
-
Zeron, M.M., Hansson, O., Chen, N., Wellington, C.L., Leavitt, B.R., Brundin, P., Hayden, M.R. and Raymond, L.A. (2002) Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease. Neuron, 33, 849-860.
-
(2002)
Neuron
, vol.33
, pp. 849-860
-
-
Zeron, M.M.1
Hansson, O.2
Chen, N.3
Wellington, C.L.4
Leavitt, B.R.5
Brundin, P.6
Hayden, M.R.7
Raymond, L.A.8
-
15
-
-
0032971311
-
Subtype-specific enhancement of NMDA receptor currents by mutant huntingtin
-
Chen, N., Luo, T., Wellington, C., Metzler, M., McCutcheon, K., Hayden, M.R. and Raymond, L.A. (1999) Subtype-specific enhancement of NMDA receptor currents by mutant huntingtin. J. Neurochem., 72, 1890-1898.
-
(1999)
J. Neurochem.
, vol.72
, pp. 1890-1898
-
-
Chen, N.1
Luo, T.2
Wellington, C.3
Metzler, M.4
McCutcheon, K.5
Hayden, M.R.6
Raymond, L.A.7
-
16
-
-
69749091508
-
Interaction of postsynaptic density protein-95 with NMDA receptors influences excitotoxicity in the yeast artificial chromosome mouse model of Huntington's disease
-
Fan, J., Cowan, C.M., Zhang, L.Y., Hayden, M.R. and Raymond, L.A. (2009) Interaction of postsynaptic density protein-95 with NMDA receptors influences excitotoxicity in the yeast artificial chromosome mouse model of Huntington's disease. J. Neurosci., 29, 10928-10938.
-
(2009)
J. Neurosci.
, vol.29
, pp. 10928-10938
-
-
Fan, J.1
Cowan, C.M.2
Zhang, L.Y.3
Hayden, M.R.4
Raymond, L.A.5
-
17
-
-
74549181538
-
Early increase in extrasynaptic NMDA receptor signaling and expression contributes to phenotype onset in Huntington's disease mice
-
Milnerwood, A.J., Gladding, C.M., Pouladi, M.A., Kaufman, A.M., Hines, R.M., Boyd, J.D., Ko, R.W., Vasuta, O.C., Graham, R.K., Hayden, M.R. et al. (2010) Early increase in extrasynaptic NMDA receptor signaling and expression contributes to phenotype onset in Huntington's disease mice. Neuron, 65, 178-190.
-
(2010)
Neuron
, vol.65
, pp. 178-190
-
-
Milnerwood, A.J.1
Gladding, C.M.2
Pouladi, M.A.3
Kaufman, A.M.4
Hines, R.M.5
Boyd, J.D.6
Ko, R.W.7
Vasuta, O.C.8
Graham, R.K.9
Hayden, M.R.10
-
18
-
-
0042357138
-
Expression of polyglutamine-expanded huntingtin induces tyrosine phosphorylation of N-methyl-D-aspartate receptors
-
Song, C., Zhang, Y., Parsons, C.G. and Liu, Y.F. (2003) Expression of polyglutamine-expanded huntingtin induces tyrosine phosphorylation of N-methyl-D-aspartate receptors. J. Biol. Chem., 278, 33364-33369.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 33364-33369
-
-
Song, C.1
Zhang, Y.2
Parsons, C.G.3
Liu, Y.F.4
-
19
-
-
0036241207
-
Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways
-
Hardingham, G.E., Fukunaga, Y. and Bading, H. (2002) Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways. Nat. Neurosci., 5, 405-414.
-
(2002)
Nat. Neurosci.
, vol.5
, pp. 405-414
-
-
Hardingham, G.E.1
Fukunaga, Y.2
Bading, H.3
-
20
-
-
57349135887
-
Neuronal viability is controlled by a functional relation between synaptic and extrasynaptic NMDA receptors
-
Leveille, F., El Gaamouch, F., Gouix, E., Lecocq, M., Lobner, D., Nicole, O. and Buisson, A. (2008) Neuronal viability is controlled by a functional relation between synaptic and extrasynaptic NMDA receptors. Faseb J., 22, 4258-4271.
-
(2008)
Faseb J
, vol.22
, pp. 4258-4271
-
-
Leveille, F.1
El Gaamouch, F.2
Gouix, E.3
Lecocq, M.4
Lobner, D.5
Nicole, O.6
Buisson, A.7
-
21
-
-
71549143207
-
Balance between synaptic versus extrasynaptic NMDA receptor activity influences inclusions and neurotoxicity of mutant huntingtin
-
Okamoto, S., Pouladi, M.A., Talantova, M., Yao, D., Xia, P., Ehrnhoefer, D.E., Zaidi, R., Clemente, A., Kaul, M., Graham, R.K. et al. (2009) Balance between synaptic versus extrasynaptic NMDA receptor activity influences inclusions and neurotoxicity of mutant huntingtin. Nat. Med., 15, 1407-1413.
-
(2009)
Nat. Med.
, vol.15
, pp. 1407-1413
-
-
Okamoto, S.1
Pouladi, M.A.2
Talantova, M.3
Yao, D.4
Xia, P.5
Ehrnhoefer, D.E.6
Zaidi, R.7
Clemente, A.8
Kaul, M.9
Graham, R.K.10
-
22
-
-
58149463218
-
Surface trafficking of N-methyl-D-aspartate receptors: physiological and pathological perspectives
-
Groc, L., Bard, L. and Choquet, D. (2009) Surface trafficking of N-methyl-D-aspartate receptors: physiological and pathological perspectives. Neuroscience, 158, 4-18.
-
(2009)
Neuroscience
, vol.158
, pp. 4-18
-
-
Groc, L.1
Bard, L.2
Choquet, D.3
-
23
-
-
77956917231
-
Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders
-
Hardingham, G.E. and Bading, H. (2010) Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders. Nat. Rev. Neurosci., 11, 682-696.
-
(2010)
Nat. Rev. Neurosci.
, vol.11
, pp. 682-696
-
-
Hardingham, G.E.1
Bading, H.2
-
24
-
-
77950370576
-
Trafficking and Targeting of NMDA Receptors
-
Van Dongen, A.M. (ed.), CRC Press, Chapter 8
-
Petralia, R.S., Al-Hallaq, R.A. and Wenthold, R.J. (2009) Trafficking and Targeting of NMDA Receptors. In Van Dongen, A.M. (ed.), Biology of the NMDA Receptor. CRC Press, Chapter 8.
-
(2009)
Biology of the NMDA Receptor
-
-
Petralia, R.S.1
Al-Hallaq, R.A.2
Wenthold, R.J.3
-
25
-
-
0034856886
-
Specific proteolysis of the NR2 subunit at multiple sites by calpain
-
Guttmann, R.P., Baker, D.L., Seifert, K.M., Cohen, A.S., Coulter, D.A. and Lynch, D.R. (2001) Specific proteolysis of the NR2 subunit at multiple sites by calpain. J. Neurochem., 78, 1083-1093.
-
(2001)
J. Neurochem.
, vol.78
, pp. 1083-1093
-
-
Guttmann, R.P.1
Baker, D.L.2
Seifert, K.M.3
Cohen, A.S.4
Coulter, D.A.5
Lynch, D.R.6
-
26
-
-
0036720464
-
Proteolysis of the N-methyl-d-aspartate receptor by calpain in situ
-
Guttmann, R.P., Sokol, S., Baker, D.L., Simpkins, K.L., Dong, Y. and Lynch, D.R. (2002) Proteolysis of the N-methyl-d-aspartate receptor by calpain in situ. J. Pharmacol. Exp. Ther., 302, 1023-1030.
-
(2002)
J. Pharmacol. Exp. Ther.
, vol.302
, pp. 1023-1030
-
-
Guttmann, R.P.1
Sokol, S.2
Baker, D.L.3
Simpkins, K.L.4
Dong, Y.5
Lynch, D.R.6
-
27
-
-
58149373434
-
Polyglutamine-modulated striatal calpain activity in YAC transgenic huntington disease mouse model: impact on NMDA receptor function and toxicity
-
Cowan, C.M., Fan, M.M., Fan, J., Shehadeh, J., Zhang, L.Y., Graham, R.K., Hayden, M.R. and Raymond, L.A. (2008) Polyglutamine-modulated striatal calpain activity in YAC transgenic huntington disease mouse model: impact on NMDA receptor function and toxicity. J. Neurosci., 28, 12725-12735.
-
(2008)
J. Neurosci.
, vol.28
, pp. 12725-12735
-
-
Cowan, C.M.1
Fan, M.M.2
Fan, J.3
Shehadeh, J.4
Zhang, L.Y.5
Graham, R.K.6
Hayden, M.R.7
Raymond, L.A.8
-
28
-
-
0037096376
-
Calpain activation in Huntington's disease
-
Gafni, J. and Ellerby, L.M. (2002) Calpain activation in Huntington's disease. J. Neurosci., 22, 4842-4849.
-
(2002)
J. Neurosci.
, vol.22
, pp. 4842-4849
-
-
Gafni, J.1
Ellerby, L.M.2
-
29
-
-
33745079669
-
Regulation of NMDA receptor trafficking and function by striatal-enriched tyrosine phosphatase (STEP)
-
Braithwaite, S.P., Adkisson, M., Leung, J., Nava, A., Masterson, B., Urfer, R., Oksenberg, D. and Nikolich, K. (2006) Regulation of NMDA receptor trafficking and function by striatal-enriched tyrosine phosphatase (STEP). Eur. J. Neurosci., 23, 2847-2856.
-
(2006)
Eur. J. Neurosci.
, vol.23
, pp. 2847-2856
-
-
Braithwaite, S.P.1
Adkisson, M.2
Leung, J.3
Nava, A.4
Masterson, B.5
Urfer, R.6
Oksenberg, D.7
Nikolich, K.8
-
30
-
-
0037187645
-
Tyrosine phosphatase STEP is a tonic brake on induction of long-term potentiation
-
Pelkey, K.A., Askalan, R., Paul, S., Kalia, L.V., Nguyen, T.H., Pitcher, G.M., Salter, M.W. and Lombroso, P.J. (2002) Tyrosine phosphatase STEP is a tonic brake on induction of long-term potentiation. Neuron, 34, 127-138.
-
(2002)
Neuron
, vol.34
, pp. 127-138
-
-
Pelkey, K.A.1
Askalan, R.2
Paul, S.3
Kalia, L.V.4
Nguyen, T.H.5
Pitcher, G.M.6
Salter, M.W.7
Lombroso, P.J.8
-
31
-
-
23044445669
-
Regulation of NMDA receptor trafficking by amyloid-beta
-
Snyder, E.M., Nong, Y., Almeida, C.G., Paul, S., Moran, T., Choi, E.Y., Nairn, A.C., Salter, M.W., Lombroso, P.J., Gouras, G.K. et al. (2005) Regulation of NMDA receptor trafficking by amyloid-beta. Nat. Neurosci., 8, 1051-1058.
-
(2005)
Nat. Neurosci.
, vol.8
, pp. 1051-1058
-
-
Snyder, E.M.1
Nong, Y.2
Almeida, C.G.3
Paul, S.4
Moran, T.5
Choi, E.Y.6
Nairn, A.C.7
Salter, M.W.8
Lombroso, P.J.9
Gouras, G.K.10
-
32
-
-
79958054247
-
Striatal-enriched protein tyrosine phosphatase expression and activity in Huntington's disease: a STEP in the resistance to excitotoxicity
-
Saavedra, A., Giralt, A., Rue, L., Xifro, X., Xu, J., Ortega, Z., Lucas, J.J., Lombroso, P.J., Alberch, J. and Perez-Navarro, E. (2011) Striatal-enriched protein tyrosine phosphatase expression and activity in Huntington's disease: a STEP in the resistance to excitotoxicity. J. Neurosci., 31, 8150-8162.
-
(2011)
J. Neurosci.
, vol.31
, pp. 8150-8162
-
-
Saavedra, A.1
Giralt, A.2
Rue, L.3
Xifro, X.4
Xu, J.5
Ortega, Z.6
Lucas, J.J.7
Lombroso, P.J.8
Alberch, J.9
Perez-Navarro, E.10
-
33
-
-
0037220735
-
NMDA-mediated activation of the tyrosine phosphatase STEP regulates the duration of ERK signaling
-
Paul, S., Nairn, A.C., Wang, P. and Lombroso, P.J. (2003) NMDA-mediated activation of the tyrosine phosphatase STEP regulates the duration of ERK signaling. Nat. Neurosci., 6, 34-42.
-
(2003)
Nat. Neurosci.
, vol.6
, pp. 34-42
-
-
Paul, S.1
Nairn, A.C.2
Wang, P.3
Lombroso, P.J.4
-
34
-
-
43549092044
-
Calcineurin is involved in the early activation of NMDA-mediated cell death in mutant huntingtin knock-in striatal cells
-
Xifro, X., Garcia-Martinez, J.M., Del Toro, D., Alberch, J. and Perez-Navarro, E. (2008) Calcineurin is involved in the early activation of NMDA-mediated cell death in mutant huntingtin knock-in striatal cells. J. Neurochem., 105, 1596-1612.
-
(2008)
J. Neurochem.
, vol.105
, pp. 1596-1612
-
-
Xifro, X.1
Garcia-Martinez, J.M.2
Del Toro, D.3
Alberch, J.4
Perez-Navarro, E.5
-
35
-
-
24644491679
-
The synaptic localization of NR2B-containing NMDA receptors is controlled by interactions with PDZ proteins and AP-2
-
Prybylowski, K., Chang, K., Sans, N., Kan, L., Vicini, S. and Wenthold, R.J. (2005) The synaptic localization of NR2B-containing NMDA receptors is controlled by interactions with PDZ proteins and AP-2. Neuron, 47, 845-857.
-
(2005)
Neuron
, vol.47
, pp. 845-857
-
-
Prybylowski, K.1
Chang, K.2
Sans, N.3
Kan, L.4
Vicini, S.5
Wenthold, R.J.6
-
36
-
-
60349088785
-
Phospho-regulation of synaptic and extrasynaptic N-methyl-d-aspartate receptors in adult hippocampal slices
-
Goebel-Goody, S.M., Davies, K.D., Alvestad Linger, R.M., Freund, R.K. and Browning, M.D. (2009) Phospho-regulation of synaptic and extrasynaptic N-methyl-d-aspartate receptors in adult hippocampal slices. Neuroscience, 158, 1446-1459.
-
(2009)
Neuroscience
, vol.158
, pp. 1446-1459
-
-
Goebel-Goody, S.M.1
Davies, K.D.2
Alvestad Linger, R.M.3
Freund, R.K.4
Browning, M.D.5
-
37
-
-
80053231513
-
Developmental localization of NMDA receptors, Src and MAP kinases in mouse brain
-
Jiang, X., Knox, R., Pathipati, P. and Ferriero, D. (2011) Developmental localization of NMDA receptors, Src and MAP kinases in mouse brain. Neurosci. Lett., 503, 215-219.
-
(2011)
Neurosci. Lett.
, vol.503
, pp. 215-219
-
-
Jiang, X.1
Knox, R.2
Pathipati, P.3
Ferriero, D.4
-
38
-
-
33947310301
-
The striatal-enriched protein tyrosine phosphatase gates long-termpotentiation and fear memory in the lateral amygdala
-
Paul, S., Olausson, P., Venkitaramani, D.V., Ruchkina, I., Moran, T.D., Tronson, N., Mills, E., Hakim, S., Salter, M.W., Taylor, J.R. et al. (2007) The striatal-enriched protein tyrosine phosphatase gates long-termpotentiation and fear memory in the lateral amygdala. Biol. Psychiatry, 61, 1049-1061.
-
(2007)
Biol. Psychiatry
, vol.61
, pp. 1049-1061
-
-
Paul, S.1
Olausson, P.2
Venkitaramani, D.V.3
Ruchkina, I.4
Moran, T.D.5
Tronson, N.6
Mills, E.7
Hakim, S.8
Salter, M.W.9
Taylor, J.R.10
-
39
-
-
54849419578
-
The tyrosine phosphatase STEP mediates AMPA receptor endocytosis after metabotropic glutamate receptor stimulation
-
Zhang, Y., Venkitaramani, D.V., Gladding, C.M., Kurup, P., Molnar, E., Collingridge, G.L. and Lombroso, P.J. (2008) The tyrosine phosphatase STEP mediates AMPA receptor endocytosis after metabotropic glutamate receptor stimulation. J. Neurosci., 28, 10561-10566.
-
(2008)
J. Neurosci.
, vol.28
, pp. 10561-10566
-
-
Zhang, Y.1
Venkitaramani, D.V.2
Gladding, C.M.3
Kurup, P.4
Molnar, E.5
Collingridge, G.L.6
Lombroso, P.J.7
-
40
-
-
34047100940
-
N-methyl-D-aspartate (NMDA) receptor function and excitotoxicity in Huntington's disease
-
Fan, M.M. and Raymond, L.A. (2007) N-methyl-D-aspartate (NMDA) receptor function and excitotoxicity in Huntington's disease. Prog. Neurobiol., 81, 272-293.
-
(2007)
Prog. Neurobiol.
, vol.81
, pp. 272-293
-
-
Fan, M.M.1
Raymond, L.A.2
-
41
-
-
77958192164
-
Early synaptic pathophysiology in neurodegeneration: insights from Huntington's disease
-
Milnerwood, A.J. and Raymond, L.A. (2010) Early synaptic pathophysiology in neurodegeneration: insights from Huntington's disease. Trends Neurosci., 33, 513-523.
-
(2010)
Trends Neurosci
, vol.33
, pp. 513-523
-
-
Milnerwood, A.J.1
Raymond, L.A.2
-
42
-
-
45049085513
-
Full length mutant huntingtin is required for altered Ca2+ signaling and apoptosis of striatal neurons in the YAC mouse model of Huntington's disease
-
Zhang, H., Li, Q., Graham, R.K., Slow, E., Hayden, M.R. and Bezprozvanny, I. (2008) Full length mutant huntingtin is required for altered Ca2+ signaling and apoptosis of striatal neurons in the YAC mouse model of Huntington's disease. Neurobiol. Dis., 31, 80-88.
-
(2008)
Neurobiol. Dis.
, vol.31
, pp. 80-88
-
-
Zhang, H.1
Li, Q.2
Graham, R.K.3
Slow, E.4
Hayden, M.R.5
Bezprozvanny, I.6
-
43
-
-
33748577363
-
Selective neuronal degeneration in Huntington's disease
-
Cowan, C.M. and Raymond, L.A. (2006) Selective neuronal degeneration in Huntington's disease. Curr. Top. Dev. Biol., 75, 25-71.
-
(2006)
Curr. Top. Dev. Biol.
, vol.75
, pp. 25-71
-
-
Cowan, C.M.1
Raymond, L.A.2
-
44
-
-
4444302167
-
Deranged neuronal calcium signaling and Huntington disease
-
Bezprozvanny, I. and Hayden, M.R. (2004) Deranged neuronal calcium signaling and Huntington disease. Biochem. Biophys. Res. Commun., 322, 1310-1317.
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.322
, pp. 1310-1317
-
-
Bezprozvanny, I.1
Hayden, M.R.2
-
45
-
-
79959506785
-
Huntington's disease, calcium, and mitochondria
-
Giacomello, M., Hudec, R. and Lopreiato, R. (2011) Huntington's disease, calcium, and mitochondria. Biofactors, 37, 206-218.
-
(2011)
Biofactors
, vol.37
, pp. 206-218
-
-
Giacomello, M.1
Hudec, R.2
Lopreiato, R.3
-
46
-
-
77953302472
-
Nature and cause of mitochondrial dysfunction in Huntington's disease: focusing on huntingtin and the striatum
-
Oliveira, J.M. (2010) Nature and cause of mitochondrial dysfunction in Huntington's disease: focusing on huntingtin and the striatum. J. Neurochem., 114, 1-12.
-
(2010)
J. Neurochem.
, vol.114
, pp. 1-12
-
-
Oliveira, J.M.1
-
47
-
-
37249083913
-
Mitochondrial sensitivity and altered calcium handling underlie enhanced NMDA-induced apoptosis in YAC128 model of Huntington's disease
-
Fernandes, H.B., Baimbridge, K.G., Church, J., Hayden, M.R. and Raymond, L.A. (2007) Mitochondrial sensitivity and altered calcium handling underlie enhanced NMDA-induced apoptosis in YAC128 model of Huntington's disease. J. Neurosci., 27, 13614-13623.
-
(2007)
J. Neurosci.
, vol.27
, pp. 13614-13623
-
-
Fernandes, H.B.1
Baimbridge, K.G.2
Church, J.3
Hayden, M.R.4
Raymond, L.A.5
-
48
-
-
2442631459
-
Inhibition of calpain cleavage of huntingtin reduces toxicity: accumulation of calpain/caspase fragments in the nucleus
-
Gafni, J., Hermel, E., Young, J.E., Wellington, C.L., Hayden, M.R. and Ellerby, L.M. (2004) Inhibition of calpain cleavage of huntingtin reduces toxicity: accumulation of calpain/caspase fragments in the nucleus. J. Biol. Chem., 279, 20211-20220.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 20211-20220
-
-
Gafni, J.1
Hermel, E.2
Young, J.E.3
Wellington, C.L.4
Hayden, M.R.5
Ellerby, L.M.6
-
49
-
-
0035940412
-
Caspase 3-cleaved N-terminal fragments of wild-type and mutant huntingtin are present in normal and Huntington's disease brains, associate with membranes, and undergo calpain-dependent proteolysis
-
Kim, Y.J., Yi, Y., Sapp, E., Wang, Y., Cuiffo, B., Kegel, K.B., Qin, Z.H., Aronin, N. and DiFiglia, M. (2001) Caspase 3-cleaved N-terminal fragments of wild-type and mutant huntingtin are present in normal and Huntington's disease brains, associate with membranes, and undergo calpain-dependent proteolysis. Proc. Natl. Acad. Sci. USA, 98, 12784-12789.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 12784-12789
-
-
Kim, Y.J.1
Yi, Y.2
Sapp, E.3
Wang, Y.4
Cuiffo, B.5
Kegel, K.B.6
Qin, Z.H.7
Aronin, N.8
DiFiglia, M.9
-
50
-
-
34547105826
-
Fyn-mediated phosphorylation of NR2B Tyr-1336 controls calpain-mediated NR2B cleavage in neurons and heterologous systems
-
Wu, H.Y., Hsu, F.C., Gleichman, A.J., Baconguis, I., Coulter, D.A. and Lynch, D.R. (2007) Fyn-mediated phosphorylation of NR2B Tyr-1336 controls calpain-mediated NR2B cleavage in neurons and heterologous systems. J. Biol. Chem., 282, 20075-20087.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 20075-20087
-
-
Wu, H.Y.1
Hsu, F.C.2
Gleichman, A.J.3
Baconguis, I.4
Coulter, D.A.5
Lynch, D.R.6
-
51
-
-
67651172947
-
Extrasynaptic NMDA receptors couple preferentially to excitotoxicity via calpain-mediated cleavage of STEP
-
Xu, J., Kurup, P., Zhang, Y., Goebel-Goody, S.M., Wu, P.H., Hawasli, A.H., Baum, M.L., Bibb, J.A. and Lombroso, P.J. (2009) Extrasynaptic NMDA receptors couple preferentially to excitotoxicity via calpain-mediated cleavage of STEP. J. Neurosci., 29, 9330-9343.
-
(2009)
J. Neurosci.
, vol.29
, pp. 9330-9343
-
-
Xu, J.1
Kurup, P.2
Zhang, Y.3
Goebel-Goody, S.M.4
Wu, P.H.5
Hawasli, A.H.6
Baum, M.L.7
Bibb, J.A.8
Lombroso, P.J.9
-
52
-
-
0346218112
-
Selective activation induced cleavage of the NR2B subunit by calpain
-
Simpkins, K.L., Guttmann, R.P., Dong, Y., Chen, Z., Sokol, S., Neumar, R.W. and Lynch, D.R. (2003) Selective activation induced cleavage of the NR2B subunit by calpain. J. Neurosci., 23, 11322-11331.
-
(2003)
J. Neurosci.
, vol.23
, pp. 11322-11331
-
-
Simpkins, K.L.1
Guttmann, R.P.2
Dong, Y.3
Chen, Z.4
Sokol, S.5
Neumar, R.W.6
Lynch, D.R.7
-
53
-
-
47949102102
-
Postsynaptic density-95 (PSD-95) and calcineurin control the sensitivity of N-methyl-D-aspartate receptors to calpain cleavage in cortical neurons
-
Yuen, E.Y., Ren, Y. and Yan, Z. (2008) Postsynaptic density-95 (PSD-95) and calcineurin control the sensitivity of N-methyl-D-aspartate receptors to calpain cleavage in cortical neurons. Mol. Pharmacol., 74, 360-370.
-
(2008)
Mol. Pharmacol.
, vol.74
, pp. 360-370
-
-
Yuen, E.Y.1
Ren, Y.2
Yan, Z.3
-
54
-
-
4143131141
-
Endocytosis and degradative sorting of NMDA receptors by conserved membrane-proximal signals
-
Scott, D.B., Michailidis, I., Mu, Y., Logothetis, D. and Ehlers, M.D. (2004) Endocytosis and degradative sorting of NMDA receptors by conserved membrane-proximal signals. J. Neurosci., 24, 7096-7109.
-
(2004)
J. Neurosci.
, vol.24
, pp. 7096-7109
-
-
Scott, D.B.1
Michailidis, I.2
Mu, Y.3
Logothetis, D.4
Ehlers, M.D.5
-
55
-
-
66449086924
-
Calpain hydrolysis of alpha- and beta2-adaptins decreases clathrin-dependent endocytosis and may promote neurodegeneration
-
Rudinskiy, N., Grishchuk, Y., Vaslin, A., Puyal, J., Delacourte, A., Hirling, H., Clarke, P.G. and Luthi-Carter, R. (2009) Calpain hydrolysis of alpha- and beta2-adaptins decreases clathrin-dependent endocytosis and may promote neurodegeneration. J. Biol. Chem., 284, 12447-12458.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 12447-12458
-
-
Rudinskiy, N.1
Grishchuk, Y.2
Vaslin, A.3
Puyal, J.4
Delacourte, A.5
Hirling, H.6
Clarke, P.G.7
Luthi-Carter, R.8
-
56
-
-
54049089271
-
Dopaminergic and glutamatergic signaling crosstalk in Huntington's disease neurodegeneration: the role of p25/cyclin-dependent kinase 5
-
Paoletti, P., Vila, I., Rife, M., Lizcano, J.M., Alberch, J. and Gines, S. (2008) Dopaminergic and glutamatergic signaling crosstalk in Huntington's disease neurodegeneration: the role of p25/cyclin-dependent kinase 5. J. Neurosci., 28, 10090-10101.
-
(2008)
J. Neurosci.
, vol.28
, pp. 10090-10101
-
-
Paoletti, P.1
Vila, I.2
Rife, M.3
Lizcano, J.M.4
Alberch, J.5
Gines, S.6
-
57
-
-
0037097287
-
Differential D1 and D2 receptor-mediated effects on immediate early gene induction in a transgenic mouse model of Huntington's disease
-
Spektor, B.S., Miller, D.W., Hollingsworth, Z.R., Kaneko, Y.A., Solano, S.M., Johnson, J.M., Penney, J.B. Jr, Young, A.B. and Luthi-Carter, R. (2002) Differential D1 and D2 receptor-mediated effects on immediate early gene induction in a transgenic mouse model of Huntington's disease. Brain Res. Mol. Brain Res., 102, 118-128.
-
(2002)
Brain Res. Mol. Brain Res.
, vol.102
, pp. 118-128
-
-
Spektor, B.S.1
Miller, D.W.2
Hollingsworth, Z.R.3
Kaneko, Y.A.4
Solano, S.M.5
Johnson, J.M.6
Penney Jr., J.B.7
Young, A.B.8
Luthi-Carter, R.9
-
58
-
-
34547411294
-
Dopaminergic signaling and striatal neurodegeneration in Huntington's disease
-
Tang, T.S., Chen, X., Liu, J. and Bezprozvanny, I. (2007) Dopaminergic signaling and striatal neurodegeneration in Huntington's disease. J. Neurosci., 27, 7899-7910.
-
(2007)
J. Neurosci.
, vol.27
, pp. 7899-7910
-
-
Tang, T.S.1
Chen, X.2
Liu, J.3
Bezprozvanny, I.4
-
59
-
-
32544432052
-
Inhibition of calcineurin by FK506 protects against polyglutamine-huntingtin toxicity through an increase of huntingtin phosphorylation at S421
-
Pardo, R., Colin, E., Regulier, E., Aebischer, P., Deglon, N., Humbert, S. and Saudou, F. (2006) Inhibition of calcineurin by FK506 protects against polyglutamine-huntingtin toxicity through an increase of huntingtin phosphorylation at S421. J. Neurosci., 26, 1635-1645.
-
(2006)
J. Neurosci.
, vol.26
, pp. 1635-1645
-
-
Pardo, R.1
Colin, E.2
Regulier, E.3
Aebischer, P.4
Deglon, N.5
Humbert, S.6
Saudou, F.7
-
60
-
-
80052936684
-
FK506 ameliorates cell death features in Huntington's disease striatal cell models
-
Rosenstock, T.R., de Brito, O.M., Lombardi, V., Louros, S., Ribeiro, M., Almeida, S., Ferreira, I.L., Oliveira, C.R. and Rego, A.C. (2011) FK506 ameliorates cell death features in Huntington's disease striatal cell models. Neurochem. Int., 59, 600-609.
-
(2011)
Neurochem. Int.
, vol.59
, pp. 600-609
-
-
Rosenstock, T.R.1
de Brito, O.M.2
Lombardi, V.3
Louros, S.4
Ribeiro, M.5
Almeida, S.6
Ferreira, I.L.7
Oliveira, C.R.8
Rego, A.C.9
-
61
-
-
33748920372
-
AMPA and NMDA glutamate receptor trafficking: multiple roads for reaching and leaving the synapse
-
Groc, L. and Choquet, D. (2006) AMPA and NMDA glutamate receptor trafficking: multiple roads for reaching and leaving the synapse. Cell Tissue Res., 326, 423-438.
-
(2006)
Cell Tissue Res
, vol.326
, pp. 423-438
-
-
Groc, L.1
Choquet, D.2
-
62
-
-
3042823541
-
Differential activity-dependent regulation of the lateral mobilities of AMPA and NMDA receptors
-
Groc, L., Heine, M., Cognet, L., Brickley, K., Stephenson, F.A., Lounis, B. and Choquet, D. (2004) Differential activity-dependent regulation of the lateral mobilities of AMPA and NMDA receptors. Nat. Neurosci., 7, 695-696.
-
(2004)
Nat. Neurosci.
, vol.7
, pp. 695-696
-
-
Groc, L.1
Heine, M.2
Cognet, L.3
Brickley, K.4
Stephenson, F.A.5
Lounis, B.6
Choquet, D.7
-
63
-
-
33845506378
-
NMDA receptor surface mobility depends on NR2A-2B subunits
-
Groc, L., Heine, M., Cousins, S.L., Stephenson, F.A., Lounis, B., Cognet, L. and Choquet, D. (2006) NMDA receptor surface mobility depends on NR2A-2B subunits. Proc. Natl. Acad. Sci. USA, 103, 18769-18774.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 18769-18774
-
-
Groc, L.1
Heine, M.2
Cousins, S.L.3
Stephenson, F.A.4
Lounis, B.5
Cognet, L.6
Choquet, D.7
-
64
-
-
34548864370
-
Culturing hippocampal neurons
-
Kaech, S. and Banker, G. (2006) Culturing hippocampal neurons. Nat. Protoc., 1, 2406-2415.
-
(2006)
Nat. Protoc.
, vol.1
, pp. 2406-2415
-
-
Kaech, S.1
Banker, G.2
-
65
-
-
0025884056
-
Efficient selection for high-expression transfectants with a novel eukaryotic vector
-
Niwa, H., Yamamura, K. and Miyazaki, J. (1991) Efficient selection for high-expression transfectants with a novel eukaryotic vector. Gene, 108, 193-199.
-
(1991)
Gene
, vol.108
, pp. 193-199
-
-
Niwa, H.1
Yamamura, K.2
Miyazaki, J.3
-
66
-
-
19544367458
-
Differential roles of NR2A- and NR2B-containing NMDA receptors in Ras-ERK signaling and AMPA receptor trafficking
-
Kim, M.J., Dunah, A.W., Wang, Y.T. and Sheng, M. (2005) Differential roles of NR2A- and NR2B-containing NMDA receptors in Ras-ERK signaling and AMPA receptor trafficking. Neuron, 46, 745-760.
-
(2005)
Neuron
, vol.46
, pp. 745-760
-
-
Kim, M.J.1
Dunah, A.W.2
Wang, Y.T.3
Sheng, M.4
-
67
-
-
59149102054
-
Neuronal pentraxins modulate cocaine-induced neuroadaptations
-
Pacchioni, A.M., Vallone, J., Worley, P.F. and Kalivas, P.W. (2009) Neuronal pentraxins modulate cocaine-induced neuroadaptations. J. Pharmacol. Exp. Ther., 328, 183-192.
-
(2009)
J. Pharmacol. Exp. Ther.
, vol.328
, pp. 183-192
-
-
Pacchioni, A.M.1
Vallone, J.2
Worley, P.F.3
Kalivas, P.W.4
-
68
-
-
0028899648
-
Cellular and molecular characterization of a brain-enriched protein tyrosine phosphatase
-
Boulanger, L.M., Lombroso, P.J., Raghunathan, A., During, M.J., Wahle, P. and Naegele, J.R. (1995) Cellular and molecular characterization of a brain-enriched protein tyrosine phosphatase. J. Neurosci., 15, 1532-1544.
-
(1995)
J. Neurosci.
, vol.15
, pp. 1532-1544
-
-
Boulanger, L.M.1
Lombroso, P.J.2
Raghunathan, A.3
During, M.J.4
Wahle, P.5
Naegele, J.R.6
-
69
-
-
77649179060
-
A neuronal role for SNAP-23 in postsynaptic glutamate receptor trafficking
-
Suh, Y.H., Terashima, A., Petralia, R.S., Wenthold, R.J., Isaac, J.T., Roche, K.W. and Roche, P.A. (2010) A neuronal role for SNAP-23 in postsynaptic glutamate receptor trafficking. Nat. Neurosci., 13, 338-343.
-
(2010)
Nat. Neurosci.
, vol.13
, pp. 338-343
-
-
Suh, Y.H.1
Terashima, A.2
Petralia, R.S.3
Wenthold, R.J.4
Isaac, J.T.5
Roche, K.W.6
Roche, P.A.7
-
70
-
-
79961232361
-
Progranulin deficiency decreases gross neural connectivity but enhances transmission at individual synapses
-
Tapia, L., Milnerwood, A., Guo, A., Mills, F., Yoshida, E., Vasuta, C., Mackenzie, I.R., Raymond, L., Cynader, M., Jia, W. et al. (2011) Progranulin deficiency decreases gross neural connectivity but enhances transmission at individual synapses. J. Neurosci., 31, 11126-11132.
-
(2011)
J. Neurosci.
, vol.31
, pp. 11126-11132
-
-
Tapia, L.1
Milnerwood, A.2
Guo, A.3
Mills, F.4
Yoshida, E.5
Vasuta, C.6
Mackenzie, I.R.7
Raymond, L.8
Cynader, M.9
Jia, W.10
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