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Volumn 12, Issue 28, 2014, Pages 5295-5303
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Marine natural products-inspired phenylmethylene hydantoins with potent in vitro and in vivo antitumor activities via suppression of Brk and FAK signaling
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Author keywords
[No Author keywords available]
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Indexed keywords
CELL CULTURE;
CELLS;
CHEMOTHERAPY;
ENZYME INHIBITION;
MAMMALS;
PHOSPHORYLATION;
TUMORS;
ANTI-PROLIFERATIVE;
ANTI-TUMOR ACTIVITIES;
MARINE NATURAL PRODUCTS;
PROSTATE CANCER CELLS;
SUBSEQUENT REDUCTION;
SUBSTITUTED BENZALDEHYDES;
TIGHT JUNCTION FORMATIONS;
WESTERN-BLOT ANALYSIS;
DISEASES;
(Z)-5-((4'-FLUOROBIPHENYL-10-YL)METHYLENE)IMIDAZOLIDINE-2,4-DIONE;
ANTINEOPLASTIC AGENT;
BENZALDEHYDE DERIVATIVE;
BIOLOGICAL PRODUCT;
FOCAL ADHESION KINASE 1;
HYDANTOIN DERIVATIVE;
PAXILLIN;
PROTEIN TYROSINE KINASE;
PTK2 PROTEIN, HUMAN;
PTK6 PROTEIN, HUMAN;
PXN PROTEIN, HUMAN;
RAC1 PROTEIN;
RAC1 PROTEIN, HUMAN;
RON PROTEIN;
TUMOR PROTEIN;
ANIMAL;
ANTAGONISTS AND INHIBITORS;
BREAST NEOPLASMS;
CELL MOTION;
CHEMISTRY;
DRUG EFFECTS;
DRUG SCREENING;
FEMALE;
GENE EXPRESSION REGULATION;
GENETICS;
HUMAN;
MALE;
METABOLISM;
MOUSE;
NUDE MOUSE;
PATHOLOGY;
PROSTATE;
SIGNAL TRANSDUCTION;
SYNTHESIS;
TRANSGENIC MOUSE;
TUMOR CELL LINE;
ANIMALS;
ANTINEOPLASTIC AGENTS;
BENZALDEHYDES;
BIOLOGICAL PRODUCTS;
BREAST NEOPLASMS;
CELL LINE, TUMOR;
CELL MOVEMENT;
FEMALE;
FOCAL ADHESION KINASE 1;
GENE EXPRESSION REGULATION, NEOPLASTIC;
HUMANS;
HYDANTOINS;
MALE;
MICE;
MICE, NUDE;
MICE, TRANSGENIC;
NEOPLASM PROTEINS;
PAXILLIN;
PROSTATE;
PROTEIN-TYROSINE KINASES;
RAC1 GTP-BINDING PROTEIN;
RECEPTOR PROTEIN-TYROSINE KINASES;
SIGNAL TRANSDUCTION;
XENOGRAFT MODEL ANTITUMOR ASSAYS;
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EID: 84903191391
PISSN: 14770520
EISSN: None
Source Type: Journal
DOI: 10.1039/c4ob00553h Document Type: Article |
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Times cited : (29)
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References (43)
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