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Volumn 2, Issue 1, 2010, Pages 88-94

Phenyl-methylene hydantoins alter CD44-specific ligand binding of benign and malignant prostate cells and suppress CD44 isoform expression

Author keywords

Alternate splicing; CD44; Fibronectin; Hyaluronan; Hydantoin; Phenyl methylene hydantoin; Prostate cancer

Indexed keywords

ANTINEOPLASTIC AGENT; BETA CATENIN; BETA1 INTEGRIN; FIBRONECTIN; FIBRONECTIN RECEPTOR; HERMES ANTIGEN; HYALURONIC ACID; HYDANTOIN DERIVATIVE; PHENYLMETHYLENE HYDANTOIN; UNCLASSIFIED DRUG;

EID: 77953398669     PISSN: None     EISSN: 19438141     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (19)

References (20)
  • 1
    • 0000698044 scopus 로고    scopus 로고
    • The loss of expression of CD44 standard and variant isoforms is related to prostatic carcinoma development and tumor progression
    • Iczkowski KA, Pantazis CG Collins, J. The loss of expression of CD44 standard and variant isoforms is related to prostatic carcinoma development and tumor progression. J Urol Pathol 1997;6:119-129.
    • (1997) J Urol Pathol , vol.6 , pp. 119-129
    • Iczkowski, K.A.1    Pantazis CG Collins, J.2
  • 2
    • 0042530237 scopus 로고    scopus 로고
    • Prostate cancer overexpresses CD44 variants 7-9 at the messenger RNA and protein level
    • Iczkowski KA, Bai S Pantazis, CG. Prostate cancer overexpresses CD44 variants 7-9 at the messenger RNA and protein level. Anticancer Res 2003;23: 3129-3140.
    • (2003) Anticancer Res , vol.23 , pp. 3129-3140
    • Iczkowski, K.A.1    Bai, S.2    Pantazis, C.G.3
  • 3
    • 3042547725 scopus 로고    scopus 로고
    • Prostate cancer invasion is influenced more by expression of a CD44 isoform including variant 9 than by Muc18
    • Omara-Opyene AL, Qiu J, Shah GV, Iczkowski KA. Prostate cancer invasion is influenced more by expression of a CD44 isoform including variant 9 than by Muc18. Lab Invest 2004;84:894-907.
    • (2004) Lab Invest , vol.84 , pp. 894-907
    • Omara-Opyene, A.L.1    Qiu, J.2    Shah, G.V.3    Iczkowski, K.A.4
  • 4
    • 33746731655 scopus 로고    scopus 로고
    • The predominant CD44 splice variant in prostate cancer binds fibronectin, and calcitonin stimulates its expression
    • Iczkowski KA, Omara-Opyene AL Shah GV. The predominant CD44 splice variant in prostate cancer binds fibronectin, and calcitonin stimulates its expression. Anticancer Res 2006;26:2863-2872.
    • (2006) Anticancer Res , vol.26 , pp. 2863-2872
    • Iczkowski, K.A.1    Omara-Opyene AL Shah, G.V.2
  • 5
    • 0036258928 scopus 로고    scopus 로고
    • Value of tissue markers p27(kip1), MIB-1, and CD44s for the pre-operative prediction of tumour features in screen-detected prostate cancer
    • Vis AN, van Rhijn BW, Noordzij MA, Schröder FH, van der Kwast TH. Value of tissue markers p27(kip1), MIB-1, and CD44s for the pre-operative prediction of tumour features in screen-detected prostate cancer. J Pathol 2002;197:148-154.
    • (2002) J Pathol , vol.197 , pp. 148-154
    • Vis, A.N.1    van Rhijn, B.W.2    Noordzij, M.A.3    Schröder, F.H.4    van der Kwast, T.H.5
  • 6
    • 0033762814 scopus 로고    scopus 로고
    • Prognostic value of cell cycle proteins p27(kip1) and MIB-1, and the cell adhesion protein CD44s in surgically treated patients with prostate cancer
    • Vis AN, Noordzij MA, Fitoz K, Wildhagen MF, Schröder FH, van der Kwast TH. Prognostic value of cell cycle proteins p27(kip1) and MIB-1, and the cell adhesion protein CD44s in surgically treated patients with prostate cancer. J Urol 2000;164:2156-2161.
    • (2000) J Urol , vol.164 , pp. 2156-2161
    • Vis, A.N.1    Noordzij, M.A.2    Fitoz, K.3    Wildhagen, M.F.4    Schröder, F.H.5    van der Kwast, T.H.6
  • 7
    • 33644875209 scopus 로고    scopus 로고
    • The influence of CD44v3-v10 on adhesion, invasion and MMP-14 expression in prostate cancer cells
    • Harrison GM, Davies G, Martin TA, Mason MD, Jiang WG. The influence of CD44v3-v10 on adhesion, invasion and MMP-14 expression in prostate cancer cells. Oncol Rep 2006;15:199-206.
    • (2006) Oncol Rep , vol.15 , pp. 199-206
    • Harrison, G.M.1    Davies, G.2    Martin, T.A.3    Mason, M.D.4    Jiang, W.G.5
  • 8
    • 60049083840 scopus 로고    scopus 로고
    • Discovery, design, and synthesis of anti-metastatic lead phenylmethylene hydantoins inspired by marine natural products
    • Mudit M, Khanfar M, Muralidharan A, Thomas S, Shah GV, van Soest RW, El Sayed KA. Discovery, design, and synthesis of anti-metastatic lead phenylmethylene hydantoins inspired by marine natural products. Bioorg Med Chem 2009;17:1731-1738.
    • (2009) Bioorg Med Chem , vol.17 , pp. 1731-1738
    • Mudit, M.1    Khanfar, M.2    Muralidharan, A.3    Thomas, S.4    Shah, G.V.5    van Soest, R.W.6    El Sayed, K.A.7
  • 9
    • 66449120262 scopus 로고    scopus 로고
    • Identification of a small molecule class to enhance cell-cell adhesion and attenuate prostate tumor growth and metastasis
    • Shah GV, Muralidharan A, Thomas S, Gokulgandhi M, Mudit M, Khanfar M, El Sayed K. Identification of a small molecule class to enhance cell-cell adhesion and attenuate prostate tumor growth and metastasis. Mol Cancer Ther 2009;8:509-520.
    • (2009) Mol Cancer Ther , vol.8 , pp. 509-520
    • Shah, G.V.1    Muralidharan, A.2    Thomas, S.3    Gokulgandhi, M.4    Mudit, M.5    Khanfar, M.6    El Sayed, K.7
  • 10
    • 0035199380 scopus 로고    scopus 로고
    • Introduction of antisense CD44s cDNA downregulates expression of overall CD44 isoforms and inhibits tumor growth and metastasis in highly metastatic colon carcinoma cells
    • Harada N, Mizoi T, Kinouchi M, Hoshi K, Ishii S, Shiiba K, Sasaki I, Matsuno S. Introduction of antisense CD44s cDNA downregulates expression of overall CD44 isoforms and inhibits tumor growth and metastasis in highly metastatic colon carcinoma cells. Int J Cancer 2001;91:67-75.
    • (2001) Int J Cancer , vol.91 , pp. 67-75
    • Harada, N.1    Mizoi, T.2    Kinouchi, M.3    Hoshi, K.4    Ishii, S.5    Shiiba, K.6    Sasaki, I.7    Matsuno, S.8
  • 11
  • 12
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-ΔΔCT) method
    • Livak KL, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-ΔΔCT) method. Methods 2001;25:402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.L.1    Schmittgen, T.D.2
  • 15
    • 70149115254 scopus 로고    scopus 로고
    • Tumor-endothelial interaction links the CD44+/CD24- phenotype with poor prognosis in early-stage breast cancer
    • Buess M, Rajski M, Vogel-Durrer BML, Herrmann R, Rochlitz C. Tumor-endothelial interaction links the CD44+/CD24- phenotype with poor prognosis in early-stage breast cancer. Neoplasia 2009;11:987-1002.
    • (2009) Neoplasia , vol.11 , pp. 987-1002
    • Buess, M.1    Rajski, M.2    Vogel-Durrer, B.M.L.3    Herrmann, R.4    Rochlitz, C.5
  • 16
    • 0032101137 scopus 로고    scopus 로고
    • Metastasis suppression by the standard CD44 isoform does not require the binding of prostate cancer cells to hyaluronate
    • Gao AC, Lou W, Sleeman JP, Isaacs JT. Metastasis suppression by the standard CD44 isoform does not require the binding of prostate cancer cells to hyaluronate. Cancer Res 1998;58:2350-2352.
    • (1998) Cancer Res , vol.58 , pp. 2350-2352
    • Gao, A.C.1    Lou, W.2    Sleeman, J.P.3    Isaacs, J.T.4
  • 18
    • 33847002689 scopus 로고    scopus 로고
    • Inhibition of the hyaluronan-CD44 interaction by merlin contributes to the tumor-suppressive activity of merlin
    • Bai Y, Liu Y, Wang H, Xu Y, Stamenkovic I, Yu Q. Inhibition of the hyaluronan-CD44 interaction by merlin contributes to the tumor-suppressive activity of merlin. Oncogene 2007;26:836-850.
    • (2007) Oncogene , vol.26 , pp. 836-850
    • Bai, Y.1    Liu, Y.2    Wang, H.3    Xu, Y.4    Stamenkovic, I.5    Yu, Q.6
  • 19
    • 44849133669 scopus 로고    scopus 로고
    • Inactivation of the NF2 tumor suppressor protein merlin in DU145 prostate cancer cells
    • Horiguchi A, Zheng R, Shen R, Nanus DM. Inactivation of the NF2 tumor suppressor protein merlin in DU145 prostate cancer cells. Prostate 2008;68:975-994.
    • (2008) Prostate , vol.68 , pp. 975-994
    • Horiguchi, A.1    Zheng, R.2    Shen, R.3    Nanus, D.M.4
  • 20
    • 67650095563 scopus 로고    scopus 로고
    • Basappa, Ananda Kumar CS, Nanjunda Swamy S, Sugahara K, Rangappa KS. Anti-tumor and anti-angiogenic activity of novel hydantoin derivatives: Inhibition of VEGF secretion in liver metastatic osteosarcoma cells. Bioorg Med Chem 2009;17:4928-4934.
    • Basappa, Ananda Kumar CS, Nanjunda Swamy S, Sugahara K, Rangappa KS. Anti-tumor and anti-angiogenic activity of novel hydantoin derivatives: Inhibition of VEGF secretion in liver metastatic osteosarcoma cells. Bioorg Med Chem 2009;17:4928-4934.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.