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Volumn 34, Issue 7, 2014, Pages 1486-1494

Rap1b in smooth muscle and endothelium is required for maintenance of vascular tone and normal blood pressure

Author keywords

relaxation; signal transduction; vasodilation

Indexed keywords

CYCLIC AMP; CYCLIC GMP DEPENDENT PROTEIN KINASE; LOSARTAN; PHENYLEPHRINE; PHOSPHATASE; PROTEIN DERIVATIVE; PROTEIN RAP1B; THROMBOXANE; UNCLASSIFIED DRUG;

EID: 84903159007     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.114.303678     Document Type: Article
Times cited : (44)

References (55)
  • 1
    • 0038460302 scopus 로고    scopus 로고
    • The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: The JNC 7 report
    • National Heart, Lung, and Blood Institute Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure; National High Blood Pressure Education Program Coordinating Committee
    • Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL Jr, Jones DW, Materson BJ, Oparil S, Wright JT Jr, Roccella EJ; National Heart, Lung, and Blood Institute Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure; National High Blood Pressure Education Program Coordinating Committee. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. JAMA. 2003;289:2560-2572.
    • (2003) JAMA , vol.289 , pp. 2560-2572
    • Chobanian, A.V.1    Bakris, G.L.2    Black, H.R.3    Cushman, W.C.4    Green, L.A.5    Izzo Jr., J.L.6    Jones, D.W.7    Materson, B.J.8    Oparil, S.9    Wright Jr., J.T.10    Roccella, E.J.11
  • 4
    • 0029995797 scopus 로고    scopus 로고
    • Rho-stimulated contractility drives the formation of stress fibers and focal adhesions
    • Chrzanowska-Wodnicka M, Burridge K. Rho-stimulated contractility drives the formation of stress fibers and focal adhesions. J Cell Biol. 1996;133:1403-1415.
    • (1996) J Cell Biol. , vol.133 , pp. 1403-1415
    • Chrzanowska-Wodnicka, M.1    Burridge, K.2
  • 5
    • 0141751697 scopus 로고    scopus 로고
    • Ca2+ sensitivity of smooth muscle and nonmuscle myosin II: Modulated by G proteins, kinases, and myosin phosphatase
    • Somlyo AP, Somlyo AV. Ca2+ sensitivity of smooth muscle and nonmuscle myosin II: modulated by G proteins, kinases, and myosin phosphatase. Physiol Rev. 2003;83:1325-1358.
    • (2003) Physiol Rev. , vol.83 , pp. 1325-1358
    • Somlyo, A.P.1    Somlyo, A.V.2
  • 6
    • 73949121819 scopus 로고    scopus 로고
    • Regulation of smooth muscle contraction by small GTPases
    • Puetz S, Lubomirov LT, Pfitzer G. Regulation of smooth muscle contraction by small GTPases. Physiology (Bethesda). 2009;24:342-356.
    • (2009) Physiology (Bethesda). , vol.24 , pp. 342-356
    • Puetz, S.1    Lubomirov, L.T.2    Pfitzer, G.3
  • 7
    • 58049213928 scopus 로고    scopus 로고
    • Mechanotransduction in vascular physiology and atherogenesis
    • Hahn C, Schwartz MA. Mechanotransduction in vascular physiology and atherogenesis. Nat Rev Mol Cell Biol. 2009;10:53-62.
    • (2009) Nat Rev Mol Cell Biol. , vol.10 , pp. 53-62
    • Hahn, C.1    Schwartz, M.A.2
  • 10
    • 77649191184 scopus 로고    scopus 로고
    • Rap1, a mercenary among the Ras-like GTPases
    • Frische EW, Zwartkruis FJ. Rap1, a mercenary among the Ras-like GTPases. Dev Biol. 2010;340:1-9.
    • (2010) Dev Biol. , vol.340 , pp. 1-9
    • Frische, E.W.1    Zwartkruis, F.J.2
  • 11
    • 84883210190 scopus 로고    scopus 로고
    • Distinct functions for rap1 signaling in vascular morphogenesis and dysfunction
    • Chrzanowska-Wodnicka M. Distinct functions for rap1 signaling in vascular morphogenesis and dysfunction. Exp Cell Res. 2013;319:2350-2359.
    • (2013) Exp Cell Res. , vol.319 , pp. 2350-2359
    • Chrzanowska-Wodnicka, M.1
  • 14
    • 40049099471 scopus 로고    scopus 로고
    • Rap1a null mice have altered myeloid cell functions suggesting distinct roles for the closely related Rap1a and 1b proteins
    • Li Y, Yan J, De P, et al. Rap1a null mice have altered myeloid cell functions suggesting distinct roles for the closely related Rap1a and 1b proteins. J Immunol. 2007;179:8322-8331.
    • (2007) J Immunol. , vol.179 , pp. 8322-8331
    • Li, Y.1    Yan, J.2    De, P.3
  • 15
    • 41949111990 scopus 로고    scopus 로고
    • Defective angiogenesis, endothelial migration, proliferation, and MAPK signaling in Rap1b-deficient mice
    • Chrzanowska-Wodnicka M, Kraus AE, Gale D, White GC II, Vansluys J. Defective angiogenesis, endothelial migration, proliferation, and MAPK signaling in Rap1b-deficient mice. Blood. 2008;111:2647-2656.
    • (2008) Blood. , vol.111 , pp. 2647-2656
    • Chrzanowska-Wodnicka, M.1    Kraus, A.E.2    Gale, D.3    White, G.C.I.I.4    Vansluys, J.5
  • 16
    • 51349163548 scopus 로고    scopus 로고
    • Rap1a is a key regulator of fibroblast growth factor 2-induced angiogenesis and together with Rap1b controls human endothelial cell functions
    • Yan J, Li F, Ingram DA, Quilliam LA. Rap1a is a key regulator of fibroblast growth factor 2-induced angiogenesis and together with Rap1b controls human endothelial cell functions. Mol Cell Biol. 2008;28:5803-5810.
    • (2008) Mol Cell Biol. , vol.28 , pp. 5803-5810
    • Yan, J.1    Li, F.2    Ingram, D.A.3    Quilliam, L.A.4
  • 18
    • 0034636121 scopus 로고    scopus 로고
    • Correction of arterial structure and endothelial dysfunction in human essential hypertension by the angiotensin receptor antagonist losartan
    • Schiffrin EL, Park JB, Intengan HD, Touyz RM. Correction of arterial structure and endothelial dysfunction in human essential hypertension by the angiotensin receptor antagonist losartan. Circulation. 2000;101:1653-1659.
    • (2000) Circulation , vol.101 , pp. 1653-1659
    • Schiffrin, E.L.1    Park, J.B.2    Intengan, H.D.3    Touyz, R.M.4
  • 19
    • 78650169348 scopus 로고    scopus 로고
    • Left ventricular hypertrophy induced by abdominal aortic banding and its prevention by angiotensin receptor blocker telmisartan-a proteomic analysis
    • Liu L, Wang W, Meng X, Gao J, Wu H, Wang P, Wu W, Wang L, Ma L, Zhang W. Left ventricular hypertrophy induced by abdominal aortic banding and its prevention by angiotensin receptor blocker telmisartan-a proteomic analysis. J Physiol Biochem. 2010;66:329-338.
    • (2010) J Physiol Biochem. , vol.66 , pp. 329-338
    • Liu, L.1    Wang, W.2    Meng, X.3    Gao, J.4    Wu, H.5    Wang, P.6    Wu, W.7    Wang, L.8    Ma, L.9    Zhang, W.10
  • 20
    • 77954993984 scopus 로고    scopus 로고
    • Effects of angiotensin type i receptor blockade on the cardiac Raf/ MEK/ERK cascade activated via adrenergic receptors
    • Zhang GX, Kimura S, Murao K, Yu X, Obata K, Matsuyoshi H, Takaki M. Effects of angiotensin type I receptor blockade on the cardiac Raf/ MEK/ERK cascade activated via adrenergic receptors. J Pharmacol Sci. 2010;113:224-233.
    • (2010) J Pharmacol Sci. , vol.113 , pp. 224-233
    • Zhang, G.X.1    Kimura, S.2    Murao, K.3    Yu, X.4    Obata, K.5    Matsuyoshi, H.6    Takaki, M.7
  • 21
    • 77049136890 scopus 로고
    • Clinical use of hydralazine and hexamethonium in treatment of hypertension
    • Hilker RR, Rhoads PS, Billings CE. Clinical use of hydralazine and hexamethonium in treatment of hypertension. J Am Med Assoc. 1953;153:5-9.
    • (1953) J Am Med Assoc. , vol.153 , pp. 5-9
    • Hilker, R.R.1    Rhoads, P.S.2    Billings, C.E.3
  • 22
  • 23
    • 0023614870 scopus 로고
    • Vasodilators and regression of left ventricular hypertrophy Hydralazine versus prazosin in hypertensive humans
    • Leenen FH, Smith DL, Farkas RM, Reeves RA, Marquez-Julio A. Vasodilators and regression of left ventricular hypertrophy. Hydralazine versus prazosin in hypertensive humans. Am J Med. 1987;82:969-978.
    • (1987) Am J Med. , vol.82 , pp. 969-978
    • Leenen, F.H.1    Smith, D.L.2    Farkas, R.M.3    Reeves, R.A.4    Marquez-Julio, A.5
  • 24
    • 0029086920 scopus 로고
    • Effects of lisinopril vs hydralazine on left ventricular hypertrophy and ambulatory blood pressure monitoring in essential hypertension
    • Fogari R, Zoppi A, Mugellini A, Tettamanti F, Lusardi P, Corradi L. Effects of lisinopril vs hydralazine on left ventricular hypertrophy and ambulatory blood pressure monitoring in essential hypertension. Eur Heart J. 1995;16:1120-1125.
    • (1995) Eur Heart J. , vol.16 , pp. 1120-1125
    • Fogari, R.1    Zoppi, A.2    Mugellini, A.3    Tettamanti, F.4    Lusardi, P.5    Corradi, L.6
  • 26
    • 33846467320 scopus 로고    scopus 로고
    • Tandem mass spectrometry measurements of creatinine in mouse plasma and urine for determining glomerular filtration rate
    • Takahashi N, Boysen G, Li F, Li Y, Swenberg JA. Tandem mass spectrometry measurements of creatinine in mouse plasma and urine for determining glomerular filtration rate. Kidney Int. 2007;71:266-271.
    • (2007) Kidney Int. , vol.71 , pp. 266-271
    • Takahashi, N.1    Boysen, G.2    Li, F.3    Li, Y.4    Swenberg, J.A.5
  • 27
    • 0030577061 scopus 로고    scopus 로고
    • The 1996 Albert Lasker Medical Research Awards the discovery of endothelium-derived relaxing factor and its importance in the identification of nitric oxide
    • Furchgott RF. The 1996 Albert Lasker Medical Research Awards. The discovery of endothelium-derived relaxing factor and its importance in the identification of nitric oxide. JAMA. 1996;276:1186-1188.
    • (1996) JAMA , vol.276 , pp. 1186-1188
    • Furchgott, R.F.1
  • 28
  • 30
    • 0037423196 scopus 로고    scopus 로고
    • Cyclic AMP-independent involvement of Rap1/B-Raf in the angiotensin II AT2 receptor signaling pathway in NG108-15 cells
    • Gendron L, Oligny JF, Payet MD, Gallo-Payet N. Cyclic AMP-independent involvement of Rap1/B-Raf in the angiotensin II AT2 receptor signaling pathway in NG108-15 cells. J Biol Chem. 2003;278:3606-3614.
    • (2003) J Biol Chem. , vol.278 , pp. 3606-3614
    • Gendron, L.1    Oligny, J.F.2    Payet, M.D.3    Gallo-Payet, N.4
  • 31
    • 0032489871 scopus 로고    scopus 로고
    • Angiotensin II activates RhoA in cardiac myocytes: A critical role of RhoA in angiotensin II-induced premyofibril formation
    • Aoki H, Izumo S, Sadoshima J. Angiotensin II activates RhoA in cardiac myocytes: a critical role of RhoA in angiotensin II-induced premyofibril formation. Circ Res. 1998;82:666-676.
    • (1998) Circ Res. , vol.82 , pp. 666-676
    • Aoki, H.1    Izumo, S.2    Sadoshima, J.3
  • 33
    • 0032420208 scopus 로고    scopus 로고
    • Evidence that additional mechanisms to cyclic GMP mediate the decrease in intracellular calcium and relaxation of rabbit aortic smooth muscle to nitric oxide
    • Weisbrod RM, Griswold MC, Yaghoubi M, Komalavilas P, Lincoln TM, Cohen RA. Evidence that additional mechanisms to cyclic GMP mediate the decrease in intracellular calcium and relaxation of rabbit aortic smooth muscle to nitric oxide. Br J Pharmacol. 1998;125:1695-1707.
    • (1998) Br J Pharmacol. , vol.125 , pp. 1695-1707
    • Weisbrod, R.M.1    Griswold, M.C.2    Yaghoubi, M.3    Komalavilas, P.4    Lincoln, T.M.5    Cohen, R.A.6
  • 34
    • 84872803761 scopus 로고    scopus 로고
    • Distinct PKA and Epac compartmentalization in airway function and plasticity
    • Dekkers BG, Racké K, Schmidt M. Distinct PKA and Epac compartmentalization in airway function and plasticity. Pharmacol Ther. 2013;137:248-265.
    • (2013) Pharmacol Ther. , vol.137 , pp. 248-265
    • Dekkers, B.G.1    Racké, K.2    Schmidt, M.3
  • 35
    • 0035816623 scopus 로고    scopus 로고
    • A CalDAG-GEFI/Rap1/B-Raf cassette couples M(1) muscarinic acetylcholine receptors to the activation of ERK1/2
    • Guo FF, Kumahara E, Saffen D. A CalDAG-GEFI/Rap1/B-Raf cassette couples M(1) muscarinic acetylcholine receptors to the activation of ERK1/2. J Biol Chem. 2001;276:25568-25581.
    • (2001) J Biol Chem. , vol.276 , pp. 25568-25581
    • Guo, F.F.1    Kumahara, E.2    Saffen, D.3
  • 36
    • 84886775399 scopus 로고    scopus 로고
    • Endothelial caveolar subcellular domain regulation of endothelial nitric oxide synthase
    • Ramadoss J, Pastore MB, Magness RR. Endothelial caveolar subcellular domain regulation of endothelial nitric oxide synthase. Clin Exp Pharmacol Physiol. 2013;40:753-764.
    • (2013) Clin Exp Pharmacol Physiol. , vol.40 , pp. 753-764
    • Ramadoss, J.1    Pastore, M.B.2    Magness, R.R.3
  • 37
    • 0030711558 scopus 로고    scopus 로고
    • Nitric oxide synthases: Which, where, how, and why?
    • Michel T, Feron O. Nitric oxide synthases: which, where, how, and why? J Clin Invest. 1997;100:2146-2152.
    • (1997) J Clin Invest , vol.100 , pp. 2146-2152
    • Michel, T.1    Feron, O.2
  • 38
    • 84859487532 scopus 로고    scopus 로고
    • Nitric oxide synthases: Regulation and function
    • 837a
    • Förstermann U, Sessa WC. Nitric oxide synthases: regulation and function. Eur Heart J. 2012;33:829-837, 837a.
    • (2012) Eur Heart J. , vol.33 , pp. 829-837
    • Förstermann, U.1    Sessa, W.C.2
  • 40
    • 47149093727 scopus 로고    scopus 로고
    • A critical role of Rap1b in B-cell trafficking and marginal zone B-cell development
    • Chen Y, Yu M, Podd A, Wen R, Chrzanowska-Wodnicka M, White GC, Wang D. A critical role of Rap1b in B-cell trafficking and marginal zone B-cell development. Blood. 2008;111:4627-4636.
    • (2008) Blood. , vol.111 , pp. 4627-4636
    • Chen, Y.1    Yu, M.2    Podd, A.3    Wen, R.4    Chrzanowska-Wodnicka, M.5    White, G.C.6    Wang, D.7
  • 42
    • 81255195551 scopus 로고    scopus 로고
    • Under pressure: The search for the essential mechanisms of hypertension
    • Coffman TM. Under pressure: the search for the essential mechanisms of hypertension. Nat Med. 2011;17:1402-1409.
    • (2011) Nat Med. , vol.17 , pp. 1402-1409
    • Coffman, T.M.1
  • 43
    • 84879440020 scopus 로고    scopus 로고
    • Assessment of renal function; Clearance, the renal microcirculation, renal blood flow, and metabolic balance
    • Beierwaltes WH, Harrison-Bernard LM, Sullivan JC, Mattson DL. Assessment of renal function; clearance, the renal microcirculation, renal blood flow, and metabolic balance. Compr Physiol. 2013;3:165-200.
    • (2013) Compr Physiol. , vol.3 , pp. 165-200
    • Beierwaltes, W.H.1    Harrison-Bernard, L.M.2    Sullivan, J.C.3    Mattson, D.L.4
  • 44
    • 77949729370 scopus 로고    scopus 로고
    • Genomewide RNA expression profiling in lung identifies distinct signatures in idiopathic pulmonary arterial hypertension and secondary pulmonary hypertension
    • Rajkumar R, Konishi K, Richards TJ, Ishizawar DC, Wiechert AC, Kaminski N, Ahmad F. Genomewide RNA expression profiling in lung identifies distinct signatures in idiopathic pulmonary arterial hypertension and secondary pulmonary hypertension. Am J Physiol Heart Circ Physiol. 2010;298:H1235-H1248.
    • (2010) Am J Physiol Heart Circ Physiol. , vol.298
    • Rajkumar, R.1    Konishi, K.2    Richards, T.J.3    Ishizawar, D.C.4    Wiechert, A.C.5    Kaminski, N.6    Ahmad, F.7
  • 45
    • 25444434962 scopus 로고    scopus 로고
    • RA-RhoGAP, Rapactivated Rho GTPase-activating protein implicated in neurite outgrowth through Rho
    • Yamada T, Sakisaka T, Hisata S, Baba T, Takai Y. RA-RhoGAP, Rapactivated Rho GTPase-activating protein implicated in neurite outgrowth through Rho. J Biol Chem. 2005;280:33026-33034.
    • (2005) J Biol Chem. , vol.280 , pp. 33026-33034
    • Yamada, T.1    Sakisaka, T.2    Hisata, S.3    Baba, T.4    Takai, Y.5
  • 46
    • 77954585854 scopus 로고    scopus 로고
    • Neurite outgrowth from PC12 cells by basic fibroblast growth factor (bFGF) is mediated by RhoA inactivation through p190RhoGAP and ARAP3
    • Jeon CY, Kim HJ, Morii H, Mori N, Settleman J, Lee JY, Kim J, Kim SC, Park JB. Neurite outgrowth from PC12 cells by basic fibroblast growth factor (bFGF) is mediated by RhoA inactivation through p190RhoGAP and ARAP3. J Cell Physiol. 2010;224:786-794.
    • (2010) J Cell Physiol. , vol.224 , pp. 786-794
    • Jeon, C.Y.1    Kim, H.J.2    Morii, H.3    Mori, N.4    Settleman, J.5    Lee, J.Y.6    Kim, J.7    Kim, S.C.8    Park, J.B.9
  • 47
    • 65449172899 scopus 로고    scopus 로고
    • CAMP-Epac2-mediated activation of Rap1 in developing male germ cells: RA-RhoGAP as a possible direct down-stream effector
    • Aivatiadou E, Ripolone M, Brunetti F, Berruti G. cAMP-Epac2-mediated activation of Rap1 in developing male germ cells: RA-RhoGAP as a possible direct down-stream effector. Mol Reprod Dev. 2009;76:407-416.
    • (2009) Mol Reprod Dev. , vol.76 , pp. 407-416
    • Aivatiadou, E.1    Ripolone, M.2    Brunetti, F.3    Berruti, G.4
  • 48
    • 84881263713 scopus 로고    scopus 로고
    • Small GTPase Rap1 regulates cell migration through regulation of small GTPase RhoA activity in response to transforming growth factor-?1
    • Moon MY, Kim HJ, Kim JG, Lee JY, Kim J, Kim SC, Choi IG, Kim PH, Park JB. Small GTPase Rap1 regulates cell migration through regulation of small GTPase RhoA activity in response to transforming growth factor-?1. J Cell Physiol. 2013;228:2119-2126.
    • (2013) J Cell Physiol. , vol.228 , pp. 2119-2126
    • Moon, M.Y.1    Kim, H.J.2    Kim, J.G.3    Lee, J.Y.4    Kim, J.5    Kim, S.C.6    Choi, I.G.7    Kim, P.H.8    Park, J.B.9
  • 49
    • 0030763619 scopus 로고    scopus 로고
    • A novel GTPase-activating protein for Rho interacts with a PDZ domain of the protein-tyrosine phosphatase PTPL1
    • Saras J, Franzén P, Aspenström P, Hellman U, Gonez LJ, Heldin CH. A novel GTPase-activating protein for Rho interacts with a PDZ domain of the protein-tyrosine phosphatase PTPL1. J Biol Chem. 1997;272: 24333-24338.
    • (1997) J Biol Chem. , vol.272 , pp. 24333-24338
    • Saras, J.1    Franzén, P.2    Aspenström, P.3    Hellman, U.4    Gonez, L.J.5    Heldin, C.H.6
  • 55
    • 84873374748 scopus 로고    scopus 로고
    • Cardiotoxic and cardioprotective features of chronic ?-adrenergic signaling
    • Zhang X, Szeto C, Gao E, et al. Cardiotoxic and cardioprotective features of chronic ?-adrenergic signaling. Circ Res. 2013;112:498-509.
    • (2013) Circ Res. , vol.112 , pp. 498-509
    • Zhang, X.1    Szeto, C.2    Gao, E.3


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