Effects of angiotensin type I receptor blockade on the cardiac Raf/MEK/ERK cascade activated via adrenergic receptors

Journal of Pharmacological Sciences

Volumn 113, Issue 3, 2010, Pages 224-233

  Zhang, Guo Xing ^a   Kimura, Shoji ^b   Murao, Koji ^b   Yu, Xiao ^b,c   Obata, Koji ^a   Matsuyoshi, Hiroko ^a   Takaki, Miyako ^a  

^a NARA MEDICAL UNIVERSITY   (Japan)

^b KAGAWA UNIVERSITY   (Japan)

^c SOOCHOW UNIVERSITY   (China)

Author keywords

Angiotensin II; Angiotensin receptor blocker; Isoproterenol; Phenylephrine; Signal transduction

Indexed keywords

ALPHA ADRENERGIC RECEPTOR; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANGIOTENSIN II; BETA ADRENERGIC RECEPTOR; CANDESARTAN; CAPTOPRIL; ISOPRENALINE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; RAF PROTEIN; RAP1 PROTEIN; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; GENE DELETION; HEART FAILURE; HEART FUNCTION; HEART VENTRICLE HYPERTROPHY; HEART VENTRICLE REMODELING; IMMUNOPRECIPITATION; MALE; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PROTEIN BINDING; PROTEIN DEFICIENCY; RAT; RECEPTOR BLOCKING; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; WILD TYPE;

EID: 77954993984     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.09336FP     Document Type: Article

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