-
1
-
-
84880508179
-
Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study
-
Kotloff KL, Nataro JP, Blackwelder WC, Nasrin D, Farag TH, Panchalingam S, Wu Y, Sow SO, Sur D, Breiman RF, Faruque AS, Zaidi AK, Saha D, Alonso PL, Tamboura B, Sanogo D, Onwuchekwa U, Manna B, Ramamurthy T, Kanungo S, Ochieng JB, Omore R, Oundo JO, Hossain A, Das SK, Ahmed S, Qureshi S, Quadri F, Adegbola RA, Antonio M, Hossain MJ, Akinsola A, Mandomando I, Nhampossa T, Acacio S, Biswas K, O'Reilly CE, Mintz ED, Berkeley LY, Muhsen K, Sommerfelt H, Robins-Browne RM, Levine MM. 2013. Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study. Lancet 382:209-222. http://dx.doi.org/10.1016/S0140-6736(13)60844-2.
-
(2013)
Lancet
, vol.382
, pp. 209-222
-
-
Kotloff, K.L.1
Nataro, J.P.2
Blackwelder, W.C.3
Nasrin, D.4
Farag, T.H.5
Panchalingam, S.6
Wu, Y.7
Sow, S.O.8
Sur, D.9
Breiman, R.F.10
Faruque, A.S.11
Zaidi, A.K.12
Saha, D.13
Alonso, P.L.14
Tamboura, B.15
Sanogo, D.16
Onwuchekwa, U.17
Manna, B.18
Ramamurthy, T.19
Kanungo, S.20
Ochieng, J.B.21
Omore, R.22
Oundo, J.O.23
Hossain, A.24
Das, S.K.25
Ahmed, S.26
Qureshi, S.27
Quadri, F.28
Adegbola, R.A.29
Antonio, M.30
Hossain, M.J.31
Akinsola, A.32
Mandomando, I.33
Nhampossa, T.34
Acacio, S.35
Biswas, K.36
O'Reilly, C.E.37
Mintz, E.D.38
Berkeley, L.Y.39
Muhsen, K.40
Sommerfelt, H.41
Robins-Browne, R.M.42
Levine, M.M.43
more..
-
2
-
-
0035095037
-
Translocated EspF protein from enteropathogenic Escherichia coli disrupts host intestinal barrier function
-
McNamara BP, Koutsouris A, O'Connell CB, Nougayrede JP, Donnenberg MS, Hecht G. 2001. Translocated EspF protein from enteropathogenic Escherichia coli disrupts host intestinal barrier function. J. Clin. Invest. 107:621-629. http://dx.doi.org/10.1172/JCI11138.
-
(2001)
J. Clin. Invest.
, vol.107
, pp. 621-629
-
-
McNamara, B.P.1
Koutsouris, A.2
O'Connell, C.B.3
Nougayrede, J.P.4
Donnenberg, M.S.5
Hecht, G.6
-
3
-
-
0038339444
-
Adhesion of enteropathogenic Escherichia coli to host cells
-
Nougayrede JP, Fernandes PJ, Donnenberg MS. 2003. Adhesion of enteropathogenic Escherichia coli to host cells. Cell. Microbiol. 5:359-372. http://dx.doi.org/10.1046/j.1462-5822.2003.00281.x.
-
(2003)
Cell. Microbiol.
, vol.5
, pp. 359-372
-
-
Nougayrede, J.P.1
Fernandes, P.J.2
Donnenberg, M.S.3
-
4
-
-
33644850203
-
Attaching and effacing pathogen-induced tight junction disruption in vivo
-
Guttman JA, Li Y, Wickham ME, Deng W, Vogl AW, Finlay BB. 2006. Attaching and effacing pathogen-induced tight junction disruption in vivo. Cell. Microbiol. 8:634-645. http://dx.doi.org/10.1111/j.1462-5822.2005.00656.x.
-
(2006)
Cell. Microbiol.
, vol.8
, pp. 634-645
-
-
Guttman, J.A.1
Li, Y.2
Wickham, M.E.3
Deng, W.4
Vogl, A.W.5
Finlay, B.B.6
-
5
-
-
84862871048
-
Defective tight junctions in refractory celiac disease
-
Schumann M, Kamel S, Pahlitzsch ML, Lebenheim L, May C, Krauss M, Hummel M, Daum S, Fromm M, Schulzke JD. 2012. Defective tight junctions in refractory celiac disease. Ann. N. Y. Acad. Sci. 1258:43-51. http://dx.doi.org/10.1111/j.1749-6632.2012.06565.x.
-
(2012)
Ann. N. Y. Acad. Sci.
, vol.1258
, pp. 43-51
-
-
Schumann, M.1
Kamel, S.2
Pahlitzsch, M.L.3
Lebenheim, L.4
May, C.5
Krauss, M.6
Hummel, M.7
Daum, S.8
Fromm, M.9
Schulzke, J.D.10
-
6
-
-
70449505391
-
Therapeutic options to modulate barrier defects in inflammatory bowel disease
-
Hering NA, Schulzke JD. 2009. Therapeutic options to modulate barrier defects in inflammatory bowel disease. Dig. Dis. 27:450-454. http://dx.doi.org/10.1159/000233283.
-
(2009)
Dig. Dis.
, vol.27
, pp. 450-454
-
-
Hering, N.A.1
Schulzke, J.D.2
-
7
-
-
84885629503
-
Enteropathogenic Escherichia coli-induced macrophage inhibitory cytokine 1 mediates cancer cell survival: an in vitro implication of infection-linked tumor dissemination
-
Choi HJ, Kim J, Do KH, Park SH, Moon Y. 2013. Enteropathogenic Escherichia coli-induced macrophage inhibitory cytokine 1 mediates cancer cell survival: an in vitro implication of infection-linked tumor dissemination. Oncogene 32:4960-4969. http://dx.doi.org/10.1038/onc.2012.508.
-
(2013)
Oncogene
, vol.32
, pp. 4960-4969
-
-
Choi, H.J.1
Kim, J.2
Do, K.H.3
Park, S.H.4
Moon, Y.5
-
8
-
-
84862834603
-
Tight junctions on the move: molecular mechanisms for epithelial barrier regulation
-
Shen L. 2012. Tight junctions on the move: molecular mechanisms for epithelial barrier regulation. Ann. N. Y. Acad. Sci. 1258:9-18. http://dx.doi.org/10.1111/j.1749-6632.2012.06613.x.
-
(2012)
Ann. N. Y. Acad. Sci.
, vol.1258
, pp. 9-18
-
-
Shen, L.1
-
9
-
-
39849108966
-
Transmembrane proteins of tight junctions
-
Chiba H, Osanai M, Murata M, Kojima T, Sawada N. 2008. Transmembrane proteins of tight junctions. Biochim. Biophys. Acta 1778: 588-600. http://dx.doi.org/10.1016/j.bbamem.2007.08.017.
-
(2008)
Biochim. Biophys. Acta
, vol.1778
, pp. 588-600
-
-
Chiba, H.1
Osanai, M.2
Murata, M.3
Kojima, T.4
Sawada, N.5
-
10
-
-
84872009116
-
Retraction of enteropathogenic E. coli type IV pili promotes efficient host cell colonization, effector translocation and tight junction disruption
-
Aroeti B, Friedman G, Zlotkin-Rivkin E, Donnenberg MS. 2012. Retraction of enteropathogenic E. coli type IV pili promotes efficient host cell colonization, effector translocation and tight junction disruption. Gut Microbes 3:267-271. http://dx.doi.org/10.4161/gmic.19814.
-
(2012)
Gut Microbes
, vol.3
, pp. 267-271
-
-
Aroeti, B.1
Friedman, G.2
Zlotkin-Rivkin, E.3
Donnenberg, M.S.4
-
11
-
-
33846807288
-
Enteropathogenic Escherichia coli, Shigella flexneri, and Listeria monocytogenes recruit a junctional protein, zonula occludens-1, to actin tails and pedestals
-
Hanajima-Ozawa M, Matsuzawa T, Fukui A, Kamitani S, Ohnishi H, Abe A, Horiguchi Y, Miyake M. 2007. Enteropathogenic Escherichia coli, Shigella flexneri, and Listeria monocytogenes recruit a junctional protein, zonula occludens-1, to actin tails and pedestals. Infect. Immun. 75:565-573. http://dx.doi.org/10.1128/IAI.01479-06.
-
(2007)
Infect. Immun.
, vol.75
, pp. 565-573
-
-
Hanajima-Ozawa, M.1
Matsuzawa, T.2
Fukui, A.3
Kamitani, S.4
Ohnishi, H.5
Abe, A.6
Horiguchi, Y.7
Miyake, M.8
-
12
-
-
0036305854
-
A membrane-permeant peptide that inhibits MLC kinase restores barrier function in in vitro models of intestinal disease
-
Zolotarevsky Y, Hecht G, Koutsouris A, Gonzalez DE, Quan C, Tom J, Mrsny RJ, Turner JR. 2002. A membrane-permeant peptide that inhibits MLC kinase restores barrier function in in vitro models of intestinal disease. Gastroenterology 123:163-172. http://dx.doi.org/10.1053/gast.2002.34235.
-
(2002)
Gastroenterology
, vol.123
, pp. 163-172
-
-
Zolotarevsky, Y.1
Hecht, G.2
Koutsouris, A.3
Gonzalez, D.E.4
Quan, C.5
Tom, J.6
Mrsny, R.J.7
Turner, J.R.8
-
13
-
-
84859423098
-
Redistribution of tight junction proteins during EPEC infection in vivo
-
Zhang Q, Li Q, Wang C, Li N, Li J. 2012. Redistribution of tight junction proteins during EPEC infection in vivo. Inflammation 35:23-32. http://dx.doi.org/10.1007/s10753-010-9285-1.
-
(2012)
Inflammation
, vol.35
, pp. 23-32
-
-
Zhang, Q.1
Li, Q.2
Wang, C.3
Li, N.4
Li, J.5
-
14
-
-
78650875210
-
Metalloprotease type III effectors that specifically cleave JNK and NF-kappaB
-
Baruch K, Gur-Arie L, Nadler C, Koby S, Yerushalmi G, Ben-Neriah Y, Yogev O, Shaulian E, Guttman C, Zarivach R, Rosenshine I. 2011. Metalloprotease type III effectors that specifically cleave JNK and NF-kappaB. EMBO J. 30:221-231. http://dx.doi.org/10.1038/emboj.2010.297.
-
(2011)
EMBO J.
, vol.30
, pp. 221-231
-
-
Baruch, K.1
Gur-Arie, L.2
Nadler, C.3
Koby, S.4
Yerushalmi, G.5
Ben-Neriah, Y.6
Yogev, O.7
Shaulian, E.8
Guttman, C.9
Zarivach, R.10
Rosenshine, I.11
-
15
-
-
77954066144
-
The type III effectors NleE and NleB from enteropathogenic E. coli and OspZ from Shigella block nuclear translocation of NF-kappaB p65
-
e1000898
-
Newton HJ, Pearson JS, Badea L, Kelly M, Lucas M, Holloway G, Wagstaff KM, Dunstone MA, Sloan J, Whisstock JC, Kaper JB, Robins-Browne RM, Jans DA, Frankel G, Phillips AD, Coulson BS, Hartland EL. 2010. The type III effectors NleE and NleB from enteropathogenic E. coli and OspZ from Shigella block nuclear translocation of NF-kappaB p65. PLoS Pathog. 6:e1000898. http://dx.doi.org/10.1371/journal.ppat.1000898.
-
(2010)
PLoS Pathog.
, vol.6
-
-
Newton, H.J.1
Pearson, J.S.2
Badea, L.3
Kelly, M.4
Lucas, M.5
Holloway, G.6
Wagstaff, K.M.7
Dunstone, M.A.8
Sloan, J.9
Whisstock, J.C.10
Kaper, J.B.11
Robins-Browne, R.M.12
Jans, D.A.13
Frankel, G.14
Phillips, A.D.15
Coulson, B.S.16
Hartland, E.L.17
-
16
-
-
0034128268
-
Role of EspB in experimental human enteropathogenic Escherichia coli infection
-
Tacket CO, Sztein MB, Losonsky G, Abe A, Finlay BB, McNamara BP, Fantry GT, James SP, Nataro JP, Levine MM, Donnenberg MS. 2000. Role of EspB in experimental human enteropathogenic Escherichia coli infection. Infect. Immun. 68:3689-3695. http://dx.doi.org/10.1128/IAI.68.6.3689-3695.2000.
-
(2000)
Infect. Immun.
, vol.68
, pp. 3689-3695
-
-
Tacket, C.O.1
Sztein, M.B.2
Losonsky, G.3
Abe, A.4
Finlay, B.B.5
McNamara, B.P.6
Fantry, G.T.7
James, S.P.8
Nataro, J.P.9
Levine, M.M.10
Donnenberg, M.S.11
-
17
-
-
79952049457
-
Intimate adherence by enteropathogenic Escherichia coli modulates TLR5 localization and proinflammatory host response in intestinal epithelial cells
-
Salazar-Gonzalez H, Navarro-Garcia F. 2011. Intimate adherence by enteropathogenic Escherichia coli modulates TLR5 localization and proinflammatory host response in intestinal epithelial cells. Scand. J. Immunol. 73:268-283. http://dx.doi.org/10.1111/j.1365-3083.2011.02507.x.
-
(2011)
Scand. J. Immunol.
, vol.73
, pp. 268-283
-
-
Salazar-Gonzalez, H.1
Navarro-Garcia, F.2
-
18
-
-
33646374141
-
Toll-like receptor 4 contributes to colitis development but not to host defense during Citrobacter rodentium infection in mice
-
Khan MA, Ma C, Knodler LA, Valdez Y, Rosenberger CM, Deng W, Finlay BB, Vallance BA. 2006. Toll-like receptor 4 contributes to colitis development but not to host defense during Citrobacter rodentium infection in mice. Infect. Immun. 74:2522-2536. http://dx.doi.org/10.1128/IAI.74.5.2522-2536.2006.
-
(2006)
Infect. Immun.
, vol.74
, pp. 2522-2536
-
-
Khan, M.A.1
Ma, C.2
Knodler, L.A.3
Valdez, Y.4
Rosenberger, C.M.5
Deng, W.6
Finlay, B.B.7
Vallance, B.A.8
-
19
-
-
84860859210
-
Role of inflammasomes in host defense against Citrobacter rodentium infection
-
Liu Z, Zaki MH, Vogel P, Gurung P, Finlay BB, Deng W, Lamkanfi M, Kanneganti TD. 2012. Role of inflammasomes in host defense against Citrobacter rodentium infection. J. Biol. Chem. 287:16955-16964. http://dx.doi.org/10.1074/jbc.M112.358705.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 16955-16964
-
-
Liu, Z.1
Zaki, M.H.2
Vogel, P.3
Gurung, P.4
Finlay, B.B.5
Deng, W.6
Lamkanfi, M.7
Kanneganti, T.D.8
-
20
-
-
33749466490
-
IFN-gamma-induced TNFR2 expression is required for TNF-dependent intestinal epithelial barrier dysfunction
-
Wang F, Schwarz BT, Graham WV, Wang Y, Su L, Clayburgh DR, Abraham C, Turner JR. 2006. IFN-gamma-induced TNFR2 expression is required for TNF-dependent intestinal epithelial barrier dysfunction. Gastroenterology 131:1153-1163. http://dx.doi.org/10.1053/j.gastro.2006.08.022.
-
(2006)
Gastroenterology
, vol.131
, pp. 1153-1163
-
-
Wang, F.1
Schwarz, B.T.2
Graham, W.V.3
Wang, Y.4
Su, L.5
Clayburgh, D.R.6
Abraham, C.7
Turner, J.R.8
-
21
-
-
13244298599
-
Interferon-gamma and tumor necrosis factor-alpha synergize to induce intestinal epithelial barrier dysfunction by up-regulating myosin light chain kinase expression
-
Wang F, Graham WV, Wang Y, Witkowski ED, Schwarz BT, Turner JR. 2005. Interferon-gamma and tumor necrosis factor-alpha synergize to induce intestinal epithelial barrier dysfunction by up-regulating myosin light chain kinase expression. Am. J. Pathol. 166:409-419. http://dx.doi.org/10.1016/S0002-9440(10)62264-X.
-
(2005)
Am. J. Pathol.
, vol.166
, pp. 409-419
-
-
Wang, F.1
Graham, W.V.2
Wang, Y.3
Witkowski, E.D.4
Schwarz, B.T.5
Turner, J.R.6
-
22
-
-
1842426940
-
A peculiar internalization of claudins, tight junction-specific adhesion molecules, during the intercellular movement of epithelial cells
-
Matsuda M, Kubo A, Furuse M, Tsukita S. 2004. A peculiar internalization of claudins, tight junction-specific adhesion molecules, during the intercellular movement of epithelial cells. J. Cell Sci. 117:1247-1257. http://dx.doi.org/10.1242/jcs.00972.
-
(2004)
J. Cell Sci.
, vol.117
, pp. 1247-1257
-
-
Matsuda, M.1
Kubo, A.2
Furuse, M.3
Tsukita, S.4
-
23
-
-
79958804398
-
Enteropathogenic and enterohaemorrhagic Escherichia coli: even more subversive elements
-
Wong AR, Pearson JS, Bright MD, Munera D, Robinson KS, Lee SF, Frankel G, Hartland EL. 2011. Enteropathogenic and enterohaemorrhagic Escherichia coli: even more subversive elements. Mol. Microbiol. 80:1420-1438. http://dx.doi.org/10.1111/j.1365-2958.2011.07661.x.
-
(2011)
Mol. Microbiol.
, vol.80
, pp. 1420-1438
-
-
Wong, A.R.1
Pearson, J.S.2
Bright, M.D.3
Munera, D.4
Robinson, K.S.5
Lee, S.F.6
Frankel, G.7
Hartland, E.L.8
-
24
-
-
84872566186
-
NleB, a bacterial effector with glycosyltransferase activity, targets GAPDH function to inhibit NF-kappaB activation
-
Gao X, Wang X, Pham TH, Feuerbacher LA, Lubos ML, Huang M, Olsen R, Mushegian A, Slawson C, Hardwidge PR. 2013. NleB, a bacterial effector with glycosyltransferase activity, targets GAPDH function to inhibit NF-kappaB activation. Cell Host Microbe 13:87-99. http://dx.doi.org/10.1016/j.chom.2012.11.010.
-
(2013)
Cell Host Microbe
, vol.13
, pp. 87-99
-
-
Gao, X.1
Wang, X.2
Pham, T.H.3
Feuerbacher, L.A.4
Lubos, M.L.5
Huang, M.6
Olsen, R.7
Mushegian, A.8
Slawson, C.9
Hardwidge, P.R.10
-
25
-
-
78651257387
-
NleC, a type III secretion protease, compromises NF-kappaB activation by targeting p65/RelA
-
e1001231
-
Yen H, Ooka T, Iguchi A, Hayashi T, Sugimoto N, Tobe T. 2010. NleC, a type III secretion protease, compromises NF-kappaB activation by targeting p65/RelA. PLoS Pathog. 6:e1001231. http://dx.doi.org/10.1371/journal.ppat.1001231.
-
(2010)
PLoS Pathog.
, vol.6
-
-
Yen, H.1
Ooka, T.2
Iguchi, A.3
Hayashi, T.4
Sugimoto, N.5
Tobe, T.6
-
26
-
-
77649216223
-
The type III secretion effector NleE inhibits NF-kappaB activation
-
e1000743
-
Nadler C, Baruch K, Kobi S, Mills E, Haviv G, Farago M, Alkalay I, Bartfeld S, Meyer TF, Ben-Neriah Y, Rosenshine I. 2010. The type III secretion effector NleE inhibits NF-kappaB activation. PLoS Pathog. 6:e1000743. http://dx.doi.org/10.1371/journal.ppat.1000743.
-
(2010)
PLoS Pathog.
, vol.6
-
-
Nadler, C.1
Baruch, K.2
Kobi, S.3
Mills, E.4
Haviv, G.5
Farago, M.6
Alkalay, I.7
Bartfeld, S.8
Meyer, T.F.9
Ben-Neriah, Y.10
Rosenshine, I.11
-
27
-
-
84883417081
-
Type I IFNs regulate effector and regulatory T cell accumulation and anti-inflammatory cytokine production during T cell-mediated colitis
-
Kole A, He J, Rivollier A, Silveira DD, Kitamura K, Maloy KJ, Kelsall BL. 2013. Type I IFNs regulate effector and regulatory T cell accumulation and anti-inflammatory cytokine production during T cell-mediated colitis. J. Immunol. 191:2771-2779. http://dx.doi.org/10.4049/jimmunol.1301093.
-
(2013)
J. Immunol.
, vol.191
, pp. 2771-2779
-
-
Kole, A.1
He, J.2
Rivollier, A.3
Silveira, D.D.4
Kitamura, K.5
Maloy, K.J.6
Kelsall, B.L.7
-
28
-
-
79951740151
-
Type I interferon inhibits interleukin-1 production and inflammasome activation
-
Guarda G, Braun M, Staehli F, Tardivel A, Mattmann C, Forster I, Farlik M, Decker T, Du Pasquier RA, Romero P, Tschopp J. 2011. Type I interferon inhibits interleukin-1 production and inflammasome activation. Immunity 34:213-223. http://dx.doi.org/10.1016/j.immuni.2011.02.006.
-
(2011)
Immunity
, vol.34
, pp. 213-223
-
-
Guarda, G.1
Braun, M.2
Staehli, F.3
Tardivel, A.4
Mattmann, C.5
Forster, I.6
Farlik, M.7
Decker, T.8
Du Pasquier, R.A.9
Romero, P.10
Tschopp, J.11
-
29
-
-
43049101640
-
The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation in mice
-
Guo B, Chang EY, Cheng G. 2008. The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation in mice. J. Clin. Invest. 118:1680-1690. http://dx.doi.org/10.1172/JCI33342.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 1680-1690
-
-
Guo, B.1
Chang, E.Y.2
Cheng, G.3
-
30
-
-
84864313594
-
Maintaining poise: commensal microbiota calibrate interferon responses
-
McAleer JP, Kolls JK. 2012. Maintaining poise: commensal microbiota calibrate interferon responses. Immunity 37:10-12. http://dx.doi.org/10.1016/j.immuni.2012.07.001.
-
(2012)
Immunity
, vol.37
, pp. 10-12
-
-
McAleer, J.P.1
Kolls, J.K.2
-
31
-
-
77954432430
-
Induction of type I interferons by bacteria
-
Monroe KM, McWhirter SM, Vance RE. 2010. Induction of type I interferons by bacteria. Cell. Microbiol. 12:881-890. http://dx.doi.org/10.1111/j.1462-5822.2010.01478.x.
-
(2010)
Cell. Microbiol.
, vol.12
, pp. 881-890
-
-
Monroe, K.M.1
McWhirter, S.M.2
Vance, R.E.3
-
32
-
-
84864311450
-
Commensal bacteria calibrate the activation threshold of innate antiviral immunity
-
Abt MC, Osborne LC, Monticelli LA, Doering TA, Alenghat T, Sonnenberg GF, Paley MA, Antenus M, Williams KL, Erikson J, Wherry EJ, Artis D. 2012. Commensal bacteria calibrate the activation threshold of innate antiviral immunity. Immunity 37:158-170. http://dx.doi.org/10.1016/j.immuni.2012.04.011.
-
(2012)
Immunity
, vol.37
, pp. 158-170
-
-
Abt, M.C.1
Osborne, L.C.2
Monticelli, L.A.3
Doering, T.A.4
Alenghat, T.5
Sonnenberg, G.F.6
Paley, M.A.7
Antenus, M.8
Williams, K.L.9
Erikson, J.10
Wherry, E.J.11
Artis, D.12
-
33
-
-
84864322646
-
Priming of natural killer cells by nonmucosal mononuclear phagocytes requires instructive signals from commensal microbiota
-
Ganal SC, Sanos SL, Kallfass C, Oberle K, Johner C, Kirschning C, Lienenklaus S, Weiss S, Staeheli P, Aichele P, Diefenbach A. 2012. Priming of natural killer cells by nonmucosal mononuclear phagocytes requires instructive signals from commensal microbiota. Immunity 37: 171-186. http://dx.doi.org/10.1016/j.immuni.2012.05.020.
-
(2012)
Immunity
, vol.37
, pp. 171-186
-
-
Ganal, S.C.1
Sanos, S.L.2
Kallfass, C.3
Oberle, K.4
Johner, C.5
Kirschning, C.6
Lienenklaus, S.7
Weiss, S.8
Staeheli, P.9
Aichele, P.10
Diefenbach, A.11
-
34
-
-
84859790202
-
Toll-like receptor-7 ligand imiquimod induces type I interferon and antimicrobial peptides to ameliorate dextran sodium sulfate-induced acute colitis
-
Sainathan SK, Bishnupuri KS, Aden K, Luo Q, Houchen CW, Anant S, Dieckgraefe BK. 2012. Toll-like receptor-7 ligand imiquimod induces type I interferon and antimicrobial peptides to ameliorate dextran sodium sulfate-induced acute colitis. Inflamm. Bowel Dis. 18:955-967. http://dx.doi.org/10.1002/ibd.21867.
-
(2012)
Inflamm. Bowel Dis.
, vol.18
, pp. 955-967
-
-
Sainathan, S.K.1
Bishnupuri, K.S.2
Aden, K.3
Luo, Q.4
Houchen, C.W.5
Anant, S.6
Dieckgraefe, B.K.7
-
35
-
-
80054810643
-
Mitochondrial antiviral signaling protein (MAVS) monitors commensal bacteria and induces an immune response that prevents experimental colitis
-
Li XD, Chiu YH, Ismail AS, Behrendt CL, Wight-Carter M, Hooper LV, Chen ZJ. 2011. Mitochondrial antiviral signaling protein (MAVS) monitors commensal bacteria and induces an immune response that prevents experimental colitis. Proc. Natl. Acad. Sci. U. S. A. 108:17390-17395. http://dx.doi.org/10.1073/pnas.1107114108.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 17390-17395
-
-
Li, X.D.1
Chiu, Y.H.2
Ismail, A.S.3
Behrendt, C.L.4
Wight-Carter, M.5
Hooper, L.V.6
Chen, Z.J.7
-
36
-
-
35348839535
-
Rig-I-/-mice develop colitis associated with downregulation of G alpha i2
-
Wang Y, Zhang HX, Sun YP, Liu ZX, Liu XS, Wang L, Lu SY, Kong H, Liu QL, Li XH, Lu ZY, Chen SJ, Chen Z, Bao SS, Dai W, Wang ZG. 2007. Rig-I-/-mice develop colitis associated with downregulation of G alpha i2. Cell Res. 17:858-868. http://dx.doi.org/10.1038/cr.2007.81.
-
(2007)
Cell Res.
, vol.17
, pp. 858-868
-
-
Wang, Y.1
Zhang, H.X.2
Sun, Y.P.3
Liu, Z.X.4
Liu, X.S.5
Wang, L.6
Lu, S.Y.7
Kong, H.8
Liu, Q.L.9
Li, X.H.10
Lu, Z.Y.11
Chen, S.J.12
Chen, Z.13
Bao, S.S.14
Dai, W.15
Wang, Z.G.16
-
37
-
-
84865000368
-
PKR protects colonic epithelium against colitis through the unfolded protein response and prosurvival signaling
-
Cao SS, Song B, Kaufman RJ. 2012. PKR protects colonic epithelium against colitis through the unfolded protein response and prosurvival signaling. Inflamm. Bowel Dis. 18:1735-1742. http://dx.doi.org/10.1002/ibd.22878.
-
(2012)
Inflamm. Bowel Dis.
, vol.18
, pp. 1735-1742
-
-
Cao, S.S.1
Song, B.2
Kaufman, R.J.3
-
38
-
-
0029151725
-
Induction of remission by interferonalpha in patients with chronic active ulcerative colitis
-
Sumer N, Palabiyikoglu M. 1995. Induction of remission by interferonalpha in patients with chronic active ulcerative colitis. Eur. J. Gastroenterol. Hepatol. 7:597-602.
-
(1995)
Eur. J. Gastroenterol. Hepatol.
, vol.7
, pp. 597-602
-
-
Sumer, N.1
Palabiyikoglu, M.2
-
39
-
-
0029166579
-
Interferon-alpha: an efficacious immunemodulating therapy for ulcerative colitis?
-
Baert F, Rutgeerts P. 1995. Interferon-alpha: an efficacious immunemodulating therapy for ulcerative colitis? Eur. J. Gastroenterol. Hepatol. 7:593-594.
-
(1995)
Eur. J. Gastroenterol. Hepatol.
, vol.7
, pp. 593-594
-
-
Baert, F.1
Rutgeerts, P.2
-
40
-
-
0035978533
-
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
-
Ogura Y, Bonen DK, Inohara N, Nicolae DL, Chen FF, Ramos R, Britton H, Moran T, Karaliuskas R, Duerr RH, Achkar JP, Brant SR, Bayless TM, Kirschner BS, Hanauer SB, Nunez G, Cho JH. 2001. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature 411:603-606. http://dx.doi.org/10.1038/35079114.
-
(2001)
Nature
, vol.411
, pp. 603-606
-
-
Ogura, Y.1
Bonen, D.K.2
Inohara, N.3
Nicolae, D.L.4
Chen, F.F.5
Ramos, R.6
Britton, H.7
Moran, T.8
Karaliuskas, R.9
Duerr, R.H.10
Achkar, J.P.11
Brant, S.R.12
Bayless, T.M.13
Kirschner, B.S.14
Hanauer, S.B.15
Nunez, G.16
Cho, J.H.17
-
41
-
-
54349095688
-
The molecular basis of NOD2 susceptibility mutations in Crohn's disease
-
Strober W, Kitani A, Fuss I, Asano N, Watanabe T. 2008. The molecular basis of NOD2 susceptibility mutations in Crohn's disease. Mucosal Immunol. 1(Suppl. 1):S5-S9. http://dx.doi.org/10.1038/mi.2008.42.
-
(2008)
Mucosal Immunol.
, vol.1
, Issue.SUPPL. 1
-
-
Strober, W.1
Kitani, A.2
Fuss, I.3
Asano, N.4
Watanabe, T.5
-
42
-
-
84864867876
-
Innate immune signalling at the intestinal epithelium in homeostasis and disease
-
Pott J, Hornef M. 2012. Innate immune signalling at the intestinal epithelium in homeostasis and disease. EMBO Rep. 13:684-698. http://dx.doi.org/10.1038/embor.2012.96.
-
(2012)
EMBO Rep.
, vol.13
, pp. 684-698
-
-
Pott, J.1
Hornef, M.2
-
43
-
-
34547176642
-
Unravelling the pathogenesis of inflammatory bowel disease
-
Xavier RJ, Podolsky DK. 2007. Unravelling the pathogenesis of inflammatory bowel disease. Nature 448:427-434. http://dx.doi.org/10.1038/nature06005.
-
(2007)
Nature
, vol.448
, pp. 427-434
-
-
Xavier, R.J.1
Podolsky, D.K.2
-
44
-
-
84860258296
-
Interferon-inducible effector mechanisms in cell-autonomous immunity
-
MacMicking JD. 2012. Interferon-inducible effector mechanisms in cell-autonomous immunity. Nat. Rev. Immunol. 12:367-382. http://dx.doi.org/10.1038/nri3210.
-
(2012)
Nat. Rev. Immunol.
, vol.12
, pp. 367-382
-
-
MacMicking, J.D.1
-
45
-
-
84879232535
-
RNase-L deficiency exacerbates experimental colitis and colitis-associated cancer
-
Long TM, Chakrabarti A, Ezelle HJ, Brennan-Laun SE, Raufman JP, Polyakova I, Silverman RH, Hassel BA. 2013. RNase-L deficiency exacerbates experimental colitis and colitis-associated cancer. Inflamm. Bowel Dis. 19:1295-1305. http://dx.doi.org/10.1097/MIB.0b013e318281f2fd.
-
(2013)
Inflamm. Bowel Dis.
, vol.19
, pp. 1295-1305
-
-
Long, T.M.1
Chakrabarti, A.2
Ezelle, H.J.3
Brennan-Laun, S.E.4
Raufman, J.P.5
Polyakova, I.6
Silverman, R.H.7
Hassel, B.A.8
-
46
-
-
37148999743
-
RIG-I has guts: identification of a role for RIG-I in colitis development
-
Solis M, Goubau D, Hiscott J. 2007. RIG-I has guts: identification of a role for RIG-I in colitis development. Cell Res. 17:974-975. http://dx.doi.org/10.1038/cr.2007.107.
-
(2007)
Cell Res.
, vol.17
, pp. 974-975
-
-
Solis, M.1
Goubau, D.2
Hiscott, J.3
-
47
-
-
34547960175
-
Small self-RNA generated by RNase L amplifies antiviral innate immunity
-
Malathi K, Dong B, Gale M, Jr, Silverman RH. 2007. Small self-RNA generated by RNase L amplifies antiviral innate immunity. Nature 448: 816-819. http://dx.doi.org/10.1038/nature06042.
-
(2007)
Nature
, vol.448
, pp. 816-819
-
-
Malathi, K.1
Dong, B.2
Gale Jr., M.3
Silverman, R.H.4
-
48
-
-
0027510449
-
Expression cloning of 2-5Adependent RNAase: a uniquely regulated mediator of interferon action
-
Zhou A, Hassel BA, Silverman RH. 1993. Expression cloning of 2-5Adependent RNAase: a uniquely regulated mediator of interferon action. Cell 72:753-765. http://dx.doi.org/10.1016/0092-8674(93)90403-D.
-
(1993)
Cell
, vol.72
, pp. 753-765
-
-
Zhou, A.1
Hassel, B.A.2
Silverman, R.H.3
-
49
-
-
0030817251
-
Interferon action and apoptosis are defective in mice devoid of 2',5\'-oligoadenylate-dependent RNase L
-
Zhou A, Paranjape J, Brown TL, Nie H, Naik S, Dong B, Chang A, Trapp B, Fairchild R, Colmenares C, Silverman RH. 1997. Interferon action and apoptosis are defective in mice devoid of 2',5\'-oligoadenylate-dependent RNase L. EMBO J. 16:6355-6363. http://dx.doi.org/10.1093/emboj/16.21.6355.
-
(1997)
EMBO J.
, vol.16
, pp. 6355-6363
-
-
Zhou, A.1
Paranjape, J.2
Brown, T.L.3
Nie, H.4
Naik, S.5
Dong, B.6
Chang, A.7
Trapp, B.8
Fairchild, R.9
Colmenares, C.10
Silverman, R.H.11
-
50
-
-
84869399905
-
Pathologic effects of RNase-L dysregulation in immunity and proliferative control
-
Ezelle HJ, Hassel BA. 2012. Pathologic effects of RNase-L dysregulation in immunity and proliferative control. Front. Biosci. (Schol. Ed.) 4:767-786. http://dx.doi.org/10.2741/298.
-
(2012)
Front. Biosci. (Schol. Ed.)
, vol.4
, pp. 767-786
-
-
Ezelle, H.J.1
Hassel, B.A.2
-
51
-
-
78651484480
-
New insights into the role of RNase L in innate immunity
-
Chakrabarti A, Jha BK, Silverman RH. 2011. New insights into the role of RNase L in innate immunity. J. Interferon Cytokine Res. 31:49-57. http://dx.doi.org/10.1089/jir.2010.0120.
-
(2011)
J. Interferon Cytokine Res.
, vol.31
, pp. 49-57
-
-
Chakrabarti, A.1
Jha, B.K.2
Silverman, R.H.3
-
52
-
-
58549103704
-
An essential role for the antiviral endoribonuclease, RNase-L, in antibacterial immunity
-
Li XL, Ezelle HJ, Kang TJ, Zhang L, Shirey KA, Harro J, Hasday JD, Mohapatra SK, Crasta OR, Vogel SN, Cross AS, Hassel BA. 2008. An essential role for the antiviral endoribonuclease, RNase-L, in antibacterial immunity. Proc. Natl. Acad. Sci. U. S. A. 105:20816-20821. http://dx.doi.org/10.1073/pnas.0807265105.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 20816-20821
-
-
Li, X.L.1
Ezelle, H.J.2
Kang, T.J.3
Zhang, L.4
Shirey, K.A.5
Harro, J.6
Hasday, J.D.7
Mohapatra, S.K.8
Crasta, O.R.9
Vogel, S.N.10
Cross, A.S.11
Hassel, B.A.12
-
53
-
-
3843101531
-
Interferon-beta stabilizes barrier characteristics of brain endothelial cells in vitro
-
Kraus J, Ling AK, Hamm S, Voigt K, Oschmann P, Engelhardt B. 2004. Interferon-beta stabilizes barrier characteristics of brain endothelial cells in vitro. Ann. Neurol. 56:192-205. http://dx.doi.org/10.1002/ana.20161.
-
(2004)
Ann. Neurol.
, vol.56
, pp. 192-205
-
-
Kraus, J.1
Ling, A.K.2
Hamm, S.3
Voigt, K.4
Oschmann, P.5
Engelhardt, B.6
-
54
-
-
84888211385
-
Type I interferon protects against pneumococcal invasive disease by inhibiting bacterial transmigration across the lung
-
e1003727
-
LeMessurier KS, Hacker H, Chi L, Tuomanen E, Redecke V. 2013. Type I interferon protects against pneumococcal invasive disease by inhibiting bacterial transmigration across the lung. PLoS Pathog. 9:e1003727. http://dx.doi.org/10.1371/journal.ppat.1003727.
-
(2013)
PLoS Pathog.
, vol.9
-
-
LeMessurier, K.S.1
Hacker, H.2
Chi, L.3
Tuomanen, E.4
Redecke, V.5
-
55
-
-
84885466567
-
In vitro evolution of an archetypal enteropathogenic Escherichia coli strain
-
Nisa S, Hazen TH, Assatourian L, Nougayrede JP, Rasko DA, Donnenberg MS. 2013. In vitro evolution of an archetypal enteropathogenic Escherichia coli strain. J. Bacteriol. 195:4476-4483. http://dx.doi.org/10.1128/JB.00704-13.
-
(2013)
J. Bacteriol.
, vol.195
, pp. 4476-4483
-
-
Nisa, S.1
Hazen, T.H.2
Assatourian, L.3
Nougayrede, J.P.4
Rasko, D.A.5
Donnenberg, M.S.6
-
56
-
-
84872871380
-
Non-neutral evolution in non-LEE-encoded type III effectors of attaching and effacing Escherichia coli
-
Eswarappa SM, Janice J, Balasundaram SV, Chakravortty D. 2013. Non-neutral evolution in non-LEE-encoded type III effectors of attaching and effacing Escherichia coli. Microbes Infect. 15:147-151. http://dx.doi.org/10.1016/j.micinf.2012.10.015.
-
(2013)
Microbes Infect.
, vol.15
, pp. 147-151
-
-
Eswarappa, S.M.1
Janice, J.2
Balasundaram, S.V.3
Chakravortty, D.4
-
57
-
-
84884137769
-
A type III effector antagonizes death receptor signalling during bacterial gut infection
-
Pearson JS, Giogha C, Ong SY, Kennedy CL, Kelly M, Robinson KS, Lung TW, Mansell A, Riedmaier P, Oates CV, Zaid A, Muhlen S, Crepin VF, Marches O, Ang CS, Williamson NA, O'Reilly LA, Bankovacki A, Nachbur U, Infusini G, Webb AI, Silke J, Strasser A, Frankel G, Hartland EL. 2013. A type III effector antagonizes death receptor signalling during bacterial gut infection. Nature 501:247-251. http://dx.doi.org/10.1038/nature12524.
-
(2013)
Nature
, vol.501
, pp. 247-251
-
-
Pearson, J.S.1
Giogha, C.2
Ong, S.Y.3
Kennedy, C.L.4
Kelly, M.5
Robinson, K.S.6
Lung, T.W.7
Mansell, A.8
Riedmaier, P.9
Oates, C.V.10
Zaid, A.11
Muhlen, S.12
Crepin, V.F.13
Marches, O.14
Ang, C.S.15
Williamson, N.A.16
O'Reilly, L.A.17
Bankovacki, A.18
Nachbur, U.19
Infusini, G.20
Webb, A.I.21
Silke, J.22
Strasser, A.23
Frankel, G.24
Hartland, E.L.25
more..
-
58
-
-
0034612342
-
One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products
-
Datsenko KA, Wanner BL. 2000. One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc. Natl. Acad. Sci. U. S. A. 97:6640-6645. http://dx.doi.org/10.1073/pnas.120163297.
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 6640-6645
-
-
Datsenko, K.A.1
Wanner, B.L.2
-
60
-
-
72149099326
-
Enteropathogenic Escherichia coli changes distribution of occludin and ZO-1 in tight junction membrane microdomains in vivo
-
Zhang Q, Li Q, Wang C, Liu X, Li N, Li J. 2010. Enteropathogenic Escherichia coli changes distribution of occludin and ZO-1 in tight junction membrane microdomains in vivo. Microb. Pathog. 48:28-34. http://dx.doi.org/10.1016/j.micpath.2009.10.002.
-
(2010)
Microb. Pathog.
, vol.48
, pp. 28-34
-
-
Zhang, Q.1
Li, Q.2
Wang, C.3
Liu, X.4
Li, N.5
Li, J.6
-
61
-
-
0027302362
-
Enteropathogenic Escherichia coli decreases the transepithelial electrical resistance of polarized epithelial monolayers
-
Canil C, Rosenshine I, Ruschkowski S, Donnenberg MS, Kaper JB, Finlay BB. 1993. Enteropathogenic Escherichia coli decreases the transepithelial electrical resistance of polarized epithelial monolayers. Infect. Immun. 61:2755-2762.
-
(1993)
Infect. Immun.
, vol.61
, pp. 2755-2762
-
-
Canil, C.1
Rosenshine, I.2
Ruschkowski, S.3
Donnenberg, M.S.4
Kaper, J.B.5
Finlay, B.B.6
-
62
-
-
10744221962
-
Interferon (IFN)-beta 1a and IFN-beta 1b block IFN-gamma-induced disintegration of endothelial junction integrity and barrier
-
Minagar A, Long A, Ma T, Jackson TH, Kelley RE, Ostanin DV, Sasaki M, Warren AC, Jawahar A, Cappell B, Alexander JS. 2003. Interferon (IFN)-beta 1a and IFN-beta 1b block IFN-gamma-induced disintegration of endothelial junction integrity and barrier. Endothelium 10:299-307. http://dx.doi.org/10.1080/714007544.
-
(2003)
Endothelium
, vol.10
, pp. 299-307
-
-
Minagar, A.1
Long, A.2
Ma, T.3
Jackson, T.H.4
Kelley, R.E.5
Ostanin, D.V.6
Sasaki, M.7
Warren, A.C.8
Jawahar, A.9
Cappell, B.10
Alexander, J.S.11
-
63
-
-
55949095576
-
Invasion of enteropathogenic Escherichia coli into host cells through epithelial tight junctions
-
Li Q, Zhang Q, Wang C, Li N, Li J. 2008. Invasion of enteropathogenic Escherichia coli into host cells through epithelial tight junctions. FEBS J. 275:6022-6032. http://dx.doi.org/10.1111/j.1742-4658.2008.06731.x.
-
(2008)
FEBS J.
, vol.275
, pp. 6022-6032
-
-
Li, Q.1
Zhang, Q.2
Wang, C.3
Li, N.4
Li, J.5
-
64
-
-
84862899672
-
Enteropathogenic E. coli effectors EspG1/G2 disrupt tight junctions: new roles and mechanisms
-
Glotfelty LG, Hecht GA. 2012. Enteropathogenic E. coli effectors EspG1/G2 disrupt tight junctions: new roles and mechanisms. Ann. N. Y. Acad. Sci. 1258:149-158. http://dx.doi.org/10.1111/j.1749-6632.2012.06563.x.
-
(2012)
Ann. N. Y. Acad. Sci.
, vol.1258
, pp. 149-158
-
-
Glotfelty, L.G.1
Hecht, G.A.2
-
65
-
-
79960289464
-
Bundle-forming pilus retraction enhances enteropathogenic Escherichia coli infectivity
-
Zahavi EE, Lieberman JA, Donnenberg MS, Nitzan M, Baruch K, Rosenshine I, Turner JR, Melamed-Book N, Feinstein N, Zlotkin-Rivkin E, Aroeti B. 2011. Bundle-forming pilus retraction enhances enteropathogenic Escherichia coli infectivity. Mol. Biol. Cell 22:2436-2447. http://dx.doi.org/10.1091/mbc.E11-01-0001.
-
(2011)
Mol. Biol. Cell
, vol.22
, pp. 2436-2447
-
-
Zahavi, E.E.1
Lieberman, J.A.2
Donnenberg, M.S.3
Nitzan, M.4
Baruch, K.5
Rosenshine, I.6
Turner, J.R.7
Melamed-Book, N.8
Feinstein, N.9
Zlotkin-Rivkin, E.10
Aroeti, B.11
-
66
-
-
34447638896
-
Enteropathogenic Escherichia coli (EPEC) inactivate innate immune responses prior to compromising epithelial barrier function
-
Ruchaud-Sparagano MH, Maresca M, Kenny B. 2007. Enteropathogenic Escherichia coli (EPEC) inactivate innate immune responses prior to compromising epithelial barrier function. Cell. Microbiol. 9:1909-1921. http://dx.doi.org/10.1111/j.1462-5822.2007.00923.x.
-
(2007)
Cell. Microbiol.
, vol.9
, pp. 1909-1921
-
-
Ruchaud-Sparagano, M.H.1
Maresca, M.2
Kenny, B.3
-
67
-
-
34548142988
-
A scientific journey through the 2-5A/RNase L system
-
Silverman RH. 2007. A scientific journey through the 2-5A/RNase L system. Cytokine Growth Factor Rev. 18:381-388. http://dx.doi.org/10.1016/j.cytogfr.2007.06.012.
-
(2007)
Cytokine Growth Factor Rev.
, vol.18
, pp. 381-388
-
-
Silverman, R.H.1
-
68
-
-
84867614408
-
A central role for RNA in the induction and biological activities of type 1 interferons
-
Li XL, Ezelle HJ, Hsi TY, Hassel BA. 2011. A central role for RNA in the induction and biological activities of type 1 interferons. Wiley Interdiscip Rev. RNA 2:58-78. http://dx.doi.org/10.1002/wrna.32.
-
(2011)
Wiley Interdiscip Rev. RNA
, vol.2
, pp. 58-78
-
-
Li, X.L.1
Ezelle, H.J.2
Hsi, T.Y.3
Hassel, B.A.4
-
69
-
-
78149324490
-
RNase L releases a small RNA from HCV RNA that refolds into a potent PAMP
-
Malathi K, Saito T, Crochet N, Barton DJ, Gale M, Jr, Silverman RH. 2010. RNase L releases a small RNA from HCV RNA that refolds into a potent PAMP. RNA 16:2108-2119. http://dx.doi.org/10.1261/rna.2244210.
-
(2010)
RNA
, vol.16
, pp. 2108-2119
-
-
Malathi, K.1
Saito, T.2
Crochet, N.3
Barton, D.J.4
Gale Jr., M.5
Silverman, R.H.6
-
70
-
-
36348987303
-
Viral encounters with 2',5'-oligoadenylate synthetase and RNase L during the interferon antiviral response
-
Silverman RH. 2007. Viral encounters with 2',5'-oligoadenylate synthetase and RNase L during the interferon antiviral response. J. Virol. 81: 12720-12729. http://dx.doi.org/10.1128/JVI.01471-07.
-
(2007)
J. Virol.
, vol.81
, pp. 12720-12729
-
-
Silverman, R.H.1
-
71
-
-
0020535757
-
rRNA cleavage as an index of ppp(A2'p)nA activity in interferon-treated encephalomyocarditis virus-infected cells
-
Silverman RH, Skehel JJ, James TC, Wreschner DH, Kerr IM. 1983. rRNA cleavage as an index of ppp(A2'p)nA activity in interferon-treated encephalomyocarditis virus-infected cells. J. Virol. 46:1051-1055.
-
(1983)
J. Virol.
, vol.46
, pp. 1051-1055
-
-
Silverman, R.H.1
Skehel, J.J.2
James, T.C.3
Wreschner, D.H.4
Kerr, I.M.5
-
72
-
-
77957236209
-
The immune system and the gut microbiota: friends or foes?
-
Cerf-Bensussan N, Gaboriau-Routhiau V. 2010. The immune system and the gut microbiota: friends or foes? Nat. Rev. Immunol. 10:735-744. http://dx.doi.org/10.1038/nri2850.
-
(2010)
Nat. Rev. Immunol.
, vol.10
, pp. 735-744
-
-
Cerf-Bensussan, N.1
Gaboriau-Routhiau, V.2
-
73
-
-
84879402478
-
The role of the immune system in governing host-microbe interactions in the intestine
-
Brown EM, Sadarangani M, Finlay BB. 2013. The role of the immune system in governing host-microbe interactions in the intestine. Nat. Immunol. 14:660-667. http://dx.doi.org/10.1038/ni.2611.
-
(2013)
Nat. Immunol.
, vol.14
, pp. 660-667
-
-
Brown, E.M.1
Sadarangani, M.2
Finlay, B.B.3
-
74
-
-
80052305157
-
Attaching and effacing bacterial effector NleC suppresses epithelial inflammatory responses by inhibiting NF-kappaB and p38 mitogen-activated protein kinase activation
-
Sham HP, Shames SR, Croxen MA, Ma C, Chan JM, Khan MA, Wickham ME, Deng W, Finlay BB, Vallance BA. 2011. Attaching and effacing bacterial effector NleC suppresses epithelial inflammatory responses by inhibiting NF-kappaB and p38 mitogen-activated protein kinase activation. Infect. Immun. 79:3552-3562. http://dx.doi.org/10.1128/IAI.05033-11.
-
(2011)
Infect. Immun.
, vol.79
, pp. 3552-3562
-
-
Sham, H.P.1
Shames, S.R.2
Croxen, M.A.3
Ma, C.4
Chan, J.M.5
Khan, M.A.6
Wickham, M.E.7
Deng, W.8
Finlay, B.B.9
Vallance, B.A.10
-
75
-
-
77958133862
-
Inhibition of NF-kappaB signaling in human dendritic cells by the enteropathogenic Escherichia coli effector protein NleE
-
Vossenkamper A, Marches O, Fairclough PD, Warnes G, Stagg AJ, Lindsay JO, Evans PC, Luong LE, Croft ANM, Naik S, Frankel G, MacDonald TT. 2010. Inhibition of NF-kappaB signaling in human dendritic cells by the enteropathogenic Escherichia coli effector protein NleE. J. Immunol. 185:4118-4127. http://dx.doi.org/10.4049/jimmunol.1000500.
-
(2010)
J. Immunol.
, vol.185
, pp. 4118-4127
-
-
Vossenkamper, A.1
Marches, O.2
Fairclough, P.D.3
Warnes, G.4
Stagg, A.J.5
Lindsay, J.O.6
Evans, P.C.7
Luong, L.E.8
Croft, A.N.M.9
Naik, S.10
Frankel, G.11
MacDonald, T.T.12
-
76
-
-
30544439770
-
MAP kinase kinase kinases and innate immunity
-
Symons A, Beinke S, Ley SC. 2006. MAP kinase kinase kinases and innate immunity. Trends Immunol. 27:40-48. http://dx.doi.org/10.1016/j.it.2005.11.007.
-
(2006)
Trends Immunol.
, vol.27
, pp. 40-48
-
-
Symons, A.1
Beinke, S.2
Ley, S.C.3
-
77
-
-
77950542752
-
Targeting Toll-like receptors: emerging therapeutics?
-
Hennessy EJ, Parker AE, O'Neill LA. 2010. Targeting Toll-like receptors: emerging therapeutics? Nat. Rev. Drug Discov. 9:293-307. http://dx.doi.org/10.1038/nrd3203.
-
(2010)
Nat. Rev. Drug Discov.
, vol.9
, pp. 293-307
-
-
Hennessy, E.J.1
Parker, A.E.2
O'Neill, L.A.3
-
78
-
-
0033145354
-
MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis
-
Kotlyarov A, Neininger A, Schubert C, Eckert R, Birchmeier C, Volk HD, Gaestel M. 1999. MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis. Nat. Cell Biol. 1:94-97. http://dx.doi.org/10.1038/10061.
-
(1999)
Nat. Cell Biol.
, vol.1
, pp. 94-97
-
-
Kotlyarov, A.1
Neininger, A.2
Schubert, C.3
Eckert, R.4
Birchmeier, C.5
Volk, H.D.6
Gaestel, M.7
-
79
-
-
0031901636
-
RNase L mediates the antiviral effect of interferon through a selective reduction in viral RNA during encephalomyocarditis virus infection
-
Li XL, Blackford JA, Hassel BA. 1998. RNase L mediates the antiviral effect of interferon through a selective reduction in viral RNA during encephalomyocarditis virus infection. J. Virol. 72:2752-2759.
-
(1998)
J. Virol.
, vol.72
, pp. 2752-2759
-
-
Li, X.L.1
Blackford, J.A.2
Hassel, B.A.3
-
80
-
-
67650472415
-
Ribosomal protein mRNAs are primary targets of regulation in RNase-L-induced senescence
-
Andersen JB, Mazan-Mamczarz K, Zhan M, Gorospe M, Hassel BA. 2009. Ribosomal protein mRNAs are primary targets of regulation in RNase-L-induced senescence. RNA Biol. 6:305-315. http://dx.doi.org/10.4161/rna.6.3.8526.
-
(2009)
RNA Biol.
, vol.6
, pp. 305-315
-
-
Andersen, J.B.1
Mazan-Mamczarz, K.2
Zhan, M.3
Gorospe, M.4
Hassel, B.A.5
-
81
-
-
84891875889
-
Lack of RNase L attenuates macrophage functions
-
e81269
-
Yi X, Zeng C, Liu H, Chen X, Zhang P, Yun BS, Jin G, Zhou A. 2013. Lack of RNase L attenuates macrophage functions. PLoS One 8:e81269. http://dx.doi.org/10.1371/journal.pone.0081269.
-
(2013)
PLoS One
, vol.8
-
-
Yi, X.1
Zeng, C.2
Liu, H.3
Chen, X.4
Zhang, P.5
Yun, B.S.6
Jin, G.7
Zhou, A.8
-
82
-
-
44149099332
-
A viral RNA competitively inhibits the antiviral endoribonuclease domain of RNase L
-
Townsend HL, Jha BK, Han JQ, Maluf NK, Silverman RH, Barton DJ. 2008. A viral RNA competitively inhibits the antiviral endoribonuclease domain of RNase L. RNA 14:1026-1036. http://dx.doi.org/10.1261/rna.958908.
-
(2008)
RNA
, vol.14
, pp. 1026-1036
-
-
Townsend, H.L.1
Jha, B.K.2
Han, J.Q.3
Maluf, N.K.4
Silverman, R.H.5
Barton, D.J.6
-
83
-
-
79952108946
-
Association of RNase L with a Ras GTPase-activating-like protein IQGAP1 in mediating the apoptosis of a human cancer cell-line
-
Sato A, Naito T, Hiramoto A, Goda K, Omi T, Kitade Y, Sasaki T, Matsuda A, Fukushima M, Wataya Y, Kim HS. 2010. Association of RNase L with a Ras GTPase-activating-like protein IQGAP1 in mediating the apoptosis of a human cancer cell-line. FEBS J. 277:4464-4473. http://dx.doi.org/10.1111/j.1742-4658.2010.07833.x.
-
(2010)
FEBS J.
, vol.277
, pp. 4464-4473
-
-
Sato, A.1
Naito, T.2
Hiramoto, A.3
Goda, K.4
Omi, T.5
Kitade, Y.6
Sasaki, T.7
Matsuda, A.8
Fukushima, M.9
Wataya, Y.10
Kim, H.S.11
-
84
-
-
58049216318
-
Actin pedestal formation by enteropathogenic Escherichia coli is regulated by IQGAP1, calcium, and calmodulin
-
Brown MD, Bry L, Li Z, Sacks DB. 2008. Actin pedestal formation by enteropathogenic Escherichia coli is regulated by IQGAP1, calcium, and calmodulin. J. Biol. Chem. 283:35212-35222. http://dx.doi.org/10.1074/jbc.M803477200.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 35212-35222
-
-
Brown, M.D.1
Bry, L.2
Li, Z.3
Sacks, D.B.4
-
85
-
-
0347093362
-
An apoptotic signaling pathway in the interferon antiviral response mediated by RNase L and c-Jun NH2-terminal kinase
-
Li G, Xiang Y, Sabapathy K, Silverman RH. 2004. An apoptotic signaling pathway in the interferon antiviral response mediated by RNase L and c-Jun NH2-terminal kinase. J. Biol. Chem. 279:1123-1131. http://dx.doi.org/10.1074/jbc.M305893200.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 1123-1131
-
-
Li, G.1
Xiang, Y.2
Sabapathy, K.3
Silverman, R.H.4
-
86
-
-
0034475135
-
Differential requirement for the stressactivated protein kinase/c-Jun NH(2)-terminal kinase in RNA damageinduced apoptosis in primary and in immortalized fibroblasts
-
Iordanov MS, Wong J, Newton DL, Rybak SM, Bright RK, Flavell RA, Davis RJ, Magun BE. 2000. Differential requirement for the stressactivated protein kinase/c-Jun NH(2)-terminal kinase in RNA damageinduced apoptosis in primary and in immortalized fibroblasts. Mol. Cell Biol. Res. Commun. 4:122-128. http://dx.doi.org/10.1006/mcbr.2000.0266.
-
(2000)
Mol. Cell Biol. Res. Commun.
, vol.4
, pp. 122-128
-
-
Iordanov, M.S.1
Wong, J.2
Newton, D.L.3
Rybak, S.M.4
Bright, R.K.5
Flavell, R.A.6
Davis, R.J.7
Magun, B.E.8
-
87
-
-
0033049125
-
Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA
-
Lai WS, Carballo E, Strum JR, Kennington EA, Phillips RS, Blackshear PJ. 1999. Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA. Mol. Cell. Biol. 19:4311-4323.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 4311-4323
-
-
Lai, W.S.1
Carballo, E.2
Strum, J.R.3
Kennington, E.A.4
Phillips, R.S.5
Blackshear, P.J.6
-
88
-
-
84877793134
-
Tristetraprolin (TTP): interactions with mRNA and proteins, and current thoughts on mechanisms of action
-
Brooks SA, Blackshear PJ. 2013. Tristetraprolin (TTP): interactions with mRNA and proteins, and current thoughts on mechanisms of action. Biochim. Biophys. Acta 1829:666-679. http://dx.doi.org/10.1016/j.bbagrm.2013.02.003.
-
(2013)
Biochim. Biophys. Acta
, vol.1829
, pp. 666-679
-
-
Brooks, S.A.1
Blackshear, P.J.2
-
89
-
-
84898721361
-
RNase-L control of cellular mRNAs: roles in biologic functions and mechanisms of substrate targeting
-
Brennan-Laun SE, Ezelle HJ, Li XL, Hassel BA. 2014. RNase-L control of cellular mRNAs: roles in biologic functions and mechanisms of substrate targeting. J. Interferon Cytokine Res. 34:275-288. http://dx.doi.org/10.1089/jir.2013.0147.
-
(2014)
J. Interferon Cytokine Res.
, vol.34
, pp. 275-288
-
-
Brennan-Laun, S.E.1
Ezelle, H.J.2
Li, X.L.3
Hassel, B.A.4
-
90
-
-
84870477645
-
Regulation of p21/CIP1/WAF-1 mediated cell-cycle arrest by RNase L and tristetraprolin, and involvement of AU-rich elements
-
Al-Haj L, Blackshear PJ, Khabar KS. 2012. Regulation of p21/CIP1/WAF-1 mediated cell-cycle arrest by RNase L and tristetraprolin, and involvement of AU-rich elements. Nucleic Acids Res. 40:7739-7752. http://dx.doi.org/10.1093/nar/gks545.
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. 7739-7752
-
-
Al-Haj, L.1
Blackshear, P.J.2
Khabar, K.S.3
-
91
-
-
33644767306
-
Posttranslational regulation of tristetraprolin subcellular localization and protein stability by p38 mitogen-activated protein kinase and extracellular signal-regulated kinase pathways
-
Brook M, Tchen CR, Santalucia T, McIlrath J, Arthur JS, Saklatvala J, Clark AR. 2006. Posttranslational regulation of tristetraprolin subcellular localization and protein stability by p38 mitogen-activated protein kinase and extracellular signal-regulated kinase pathways. Mol. Cell. Biol. 26:2408-2418. http://dx.doi.org/10.1128/MCB.26.6.2408-2418.2006.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 2408-2418
-
-
Brook, M.1
Tchen, C.R.2
Santalucia, T.3
McIlrath, J.4
Arthur, J.S.5
Saklatvala, J.6
Clark, A.R.7
-
92
-
-
3543003469
-
The stability of tristetraprolin mRNA is regulated by mitogen-activated protein kinase p38 and by tristetraprolin itself
-
Tchen CR, Brook M, Saklatvala J, Clark AR. 2004. The stability of tristetraprolin mRNA is regulated by mitogen-activated protein kinase p38 and by tristetraprolin itself. J. Biol. Chem. 279:32393-32400. http://dx.doi.org/10.1074/jbc.M402059200.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 32393-32400
-
-
Tchen, C.R.1
Brook, M.2
Saklatvala, J.3
Clark, A.R.4
-
93
-
-
33644753147
-
Mitogenactivated protein kinase-activated protein kinase 2 regulates tumor necrosis factor mRNA stability and translation mainly by altering tristetraprolin expression, stability, and binding to adenine/uridine-rich element
-
Hitti E, Iakovleva T, Brook M, Deppenmeier S, Gruber AD, Radzioch D, Clark AR, Blackshear PJ, Kotlyarov A, Gaestel M. 2006. Mitogenactivated protein kinase-activated protein kinase 2 regulates tumor necrosis factor mRNA stability and translation mainly by altering tristetraprolin expression, stability, and binding to adenine/uridine-rich element. Mol. Cell. Biol. 26:2399-2407. http://dx.doi.org/10.1128/MCB.26.6.2399-2407.2006.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 2399-2407
-
-
Hitti, E.1
Iakovleva, T.2
Brook, M.3
Deppenmeier, S.4
Gruber, A.D.5
Radzioch, D.6
Clark, A.R.7
Blackshear, P.J.8
Kotlyarov, A.9
Gaestel, M.10
-
94
-
-
33745064871
-
Interferons limit inflammatory responses by induction of tristetraprolin
-
Sauer I, Schaljo B, Vogl C, Gattermeier I, Kolbe T, Muller M, Blackshear PJ, Kovarik P. 2006. Interferons limit inflammatory responses by induction of tristetraprolin. Blood 107:4790-4797. http://dx.doi.org/10.1182/blood-2005-07-3058.
-
(2006)
Blood
, vol.107
, pp. 4790-4797
-
-
Sauer, I.1
Schaljo, B.2
Vogl, C.3
Gattermeier, I.4
Kolbe, T.5
Muller, M.6
Blackshear, P.J.7
Kovarik, P.8
-
95
-
-
37049037995
-
Molecular mechanisms of the anti-inflammatory functions of interferons
-
Kovarik P, Sauer I, Schaljo B. 2007. Molecular mechanisms of the anti-inflammatory functions of interferons. Immunobiology 212:895-901. http://dx.doi.org/10.1016/j.imbio.2007.09.011.
-
(2007)
Immunobiology
, vol.212
, pp. 895-901
-
-
Kovarik, P.1
Sauer, I.2
Schaljo, B.3
-
96
-
-
0033853899
-
Enteropathogenic Escherichia coli dephosphorylates and dissociates occludin from intestinal epithelial tight junctions
-
Simonovic I, Rosenberg J, Koutsouris A, Hecht G. 2000. Enteropathogenic Escherichia coli dephosphorylates and dissociates occludin from intestinal epithelial tight junctions. Cell. Microbiol. 2:305-315. http://dx.doi.org/10.1046/j.1462-5822.2000.00055.x.
-
(2000)
Cell. Microbiol.
, vol.2
, pp. 305-315
-
-
Simonovic, I.1
Rosenberg, J.2
Koutsouris, A.3
Hecht, G.4
-
97
-
-
67249107604
-
Tight junctions and enteropathogenic E. coli
-
Weflen AW, Alto NM, Hecht GA. 2009. Tight junctions and enteropathogenic E. coli. Ann. N. Y. Acad. Sci. 1165:169-174. http://dx.doi.org/10.1111/j.1749-6632.2009.04060.x.
-
(2009)
Ann. N. Y. Acad. Sci.
, vol.1165
, pp. 169-174
-
-
Weflen, A.W.1
Alto, N.M.2
Hecht, G.A.3
-
98
-
-
84876575052
-
Interferome v2.0: an updated database of annotated interferon-regulated genes
-
Rusinova I, Forster S, Yu S, Kannan A, Masse M, Cumming H, Chapman R, Hertzog PJ. 2013. Interferome v2.0: an updated database of annotated interferon-regulated genes. Nucleic Acids Res. 41:D1040-D1046. http://dx.doi.org/10.1093/nar/gks1215.
-
(2013)
Nucleic Acids Res.
, vol.41
-
-
Rusinova, I.1
Forster, S.2
Yu, S.3
Kannan, A.4
Masse, M.5
Cumming, H.6
Chapman, R.7
Hertzog, P.J.8
-
99
-
-
84873292281
-
IFITM1 is a tight junction protein that inhibits hepatitis C virus entry
-
Wilkins C, Woodward J, Lau DT, Barnes A, Joyce M, McFarlane N, McKeating JA, Tyrrell DL, Gale M, Jr. 2013. IFITM1 is a tight junction protein that inhibits hepatitis C virus entry. Hepatology 57:461-469. http://dx.doi.org/10.1002/hep.26066.
-
(2013)
Hepatology
, vol.57
, pp. 461-469
-
-
Wilkins, C.1
Woodward, J.2
Lau, D.T.3
Barnes, A.4
Joyce, M.5
McFarlane, N.6
McKeating, J.A.7
Tyrrell, D.L.8
Gale Jr., M.9
-
100
-
-
0021845478
-
(2'-5')oligo adenylate synthetase activity in leucocytes of patients with inflammatory bowel disease
-
Stalnikowicz R, Goder K, Karmeli F, Fiocchi C, Rachmilewitz D. 1985. (2'-5')oligo adenylate synthetase activity in leucocytes of patients with inflammatory bowel disease. Gut 26:556-561. http://dx.doi.org/10.1136/gut.26.6.556.
-
(1985)
Gut
, vol.26
, pp. 556-561
-
-
Stalnikowicz, R.1
Goder, K.2
Karmeli, F.3
Fiocchi, C.4
Rachmilewitz, D.5
-
101
-
-
74549206702
-
How the noninflammasome NLRs function in the innate immune system
-
Ting JP, Duncan JA, Lei Y. 2010. How the noninflammasome NLRs function in the innate immune system. Science 327:286-290. http://dx.doi.org/10.1126/science.1184004.
-
(2010)
Science
, vol.327
, pp. 286-290
-
-
Ting, J.P.1
Duncan, J.A.2
Lei, Y.3
-
102
-
-
70450223512
-
Nucleotide oligomerization domain-2 interacts with 2'-5'-oligoadenylate synthetase type 2 and enhances RNase-L function in THP-1 cells
-
Dugan JW, Albor A, David L, Fowlkes J, Blackledge MT, Martin TM, Planck SR, Rosenzweig HL, Rosenbaum JT, Davey MP. 2009. Nucleotide oligomerization domain-2 interacts with 2'-5'-oligoadenylate synthetase type 2 and enhances RNase-L function in THP-1 cells. Mol. Immunol. 47:560-566. http://dx.doi.org/10.1016/j.molimm.2009.09.025.
-
(2009)
Mol. Immunol.
, vol.47
, pp. 560-566
-
-
Dugan, J.W.1
Albor, A.2
David, L.3
Fowlkes, J.4
Blackledge, M.T.5
Martin, T.M.6
Planck, S.R.7
Rosenzweig, H.L.8
Rosenbaum, J.T.9
Davey, M.P.10
-
103
-
-
84871601752
-
RNase L induces autophagy via c-Jun N-terminal kinase and double-stranded RNA-dependent protein kinase signaling pathways
-
Siddiqui MA, Malathi K. 2012. RNase L induces autophagy via c-Jun N-terminal kinase and double-stranded RNA-dependent protein kinase signaling pathways. J. Biol. Chem. 287:43651-43664. http://dx.doi.org/10.1074/jbc.M112.399964.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 43651-43664
-
-
Siddiqui, M.A.1
Malathi, K.2
-
104
-
-
84869057548
-
RNase L triggers autophagy in response to viral infections
-
Chakrabarti A, Ghosh PK, Banerjee S, Gaughan C, Silverman RH. 2012. RNase L triggers autophagy in response to viral infections. J. Virol. 86:11311-11321. http://dx.doi.org/10.1128/JVI.00270-12.
-
(2012)
J. Virol.
, vol.86
, pp. 11311-11321
-
-
Chakrabarti, A.1
Ghosh, P.K.2
Banerjee, S.3
Gaughan, C.4
Silverman, R.H.5
|