메뉴 건너뛰기




Volumn 72, Issue 4, 1998, Pages 2752-2759

RNase L mediates the antiviral effect of interferon through a selective reduction in vital RNA during encephalomyocarditis virus infection

Author keywords

[No Author keywords available]

Indexed keywords

INTERFERON; RIBONUCLEASE;

EID: 0031901636     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.72.4.2752-2759.1998     Document Type: Article
Times cited : (113)

References (57)
  • 1
    • 0021129005 scopus 로고
    • A2′p5A′ blocks vesicular stomatitis virus replication in intact cells
    • Alarcon, B., H. Bugany, and L. Carrasco. 1984. pppA2′p5A′ blocks vesicular stomatitis virus replication in intact cells. J. Virol. 52:183-187.
    • (1984) J. Virol. , vol.52 , pp. 183-187
    • Alarcon, B.1    Bugany, H.2    Carrasco, L.3
  • 2
    • 0021705755 scopus 로고
    • Cleavage of nascent reovirus mRNA by localized activation of the 2′-5′-oligoadenylate-dependent endoribonuclease
    • Baglioni, C., A. DeBenedetti, and G. J. Williams. 1984. Cleavage of nascent reovirus mRNA by localized activation of the 2′-5′-oligoadenylate-dependent endoribonuclease. J. Virol. 52:865-871.
    • (1984) J. Virol. , vol.52 , pp. 865-871
    • Baglioni, C.1    DeBenedetti, A.2    Williams, G.J.3
  • 3
    • 0013921592 scopus 로고
    • Aspects of synthesis of poliovirus RNA and the formation of virus particles
    • Baltimore, D., M. Girard, and J. E. Darnell. 1966. Aspects of synthesis of poliovirus RNA and the formation of virus particles. Virology 29:179-189.
    • (1966) Virology , vol.29 , pp. 179-189
    • Baltimore, D.1    Girard, M.2    Darnell, J.E.3
  • 4
    • 0022981641 scopus 로고
    • Molecular characterization of the interferon-induced 15-kDa protein
    • Blostrom, D. C., S. Fahey, R. Kutny, B. D. Korand, and E. Knight, Jr. 1986. Molecular characterization of the interferon-induced 15-kDa protein. J. Biol. Chem. 261:8811-8816.
    • (1986) J. Biol. Chem. , vol.261 , pp. 8811-8816
    • Blostrom, D.C.1    Fahey, S.2    Kutny, R.3    Korand, B.D.4    Knight Jr., E.5
  • 5
    • 0029076509 scopus 로고
    • Cloning and characterization of an RNase-L inhibitor: A new component of the interferon-regulated 2-5a pathway
    • Brisbal, C., C. Martinand, M. Silhol, B. LeBleu, and Salehzada, T. 1995. Cloning and characterization of an RNase-L inhibitor: a new component of the interferon-regulated 2-5A pathway. J. Biol. Chem. 270:13308-13317.
    • (1995) J. Biol. Chem. , vol.270 , pp. 13308-13317
    • Brisbal, C.1    Martinand, C.2    Silhol, M.3    LeBleu, B.4    Salehzada, T.5
  • 7
    • 0020030021 scopus 로고
    • Virus-mediated inhibition of the ppp(A2′p)nA system and its prevention by interferon
    • Cayley, P. J., M. Knight, and I. M. Kerr. 1982. Virus-mediated inhibition of the ppp(A2′p)nA system and its prevention by interferon. Biochem. Biophys. Res. Commun. 104:376-382.
    • (1982) Biochem. Biophys. Res. Commun. , vol.104 , pp. 376-382
    • Cayley, P.J.1    Knight, M.2    Kerr, I.M.3
  • 8
    • 0023650344 scopus 로고
    • Constitutive expression of (2′-5′)oligo a synthetase confers resistance to picornavirus infection
    • Chebath, J., P. Benech, M. Revel, and M. Vigneron. 1987. Constitutive expression of (2′-5′)oligo A synthetase confers resistance to picornavirus infection. Nature 330:587-588.
    • (1987) Nature , vol.330 , pp. 587-588
    • Chebath, J.1    Benech, P.2    Revel, M.3    Vigneron, M.4
  • 9
    • 0017948303 scopus 로고
    • Inhibition of cell-free protein synthesis by pppA2′p5′A2′p5′A: A novel oligonucleotide synthesized by interferon-treated L cell extracts
    • Clemmens, M. J., and B. R. G. Williams. 1978. Inhibition of cell-free protein synthesis by pppA2′p5′A2′p5′A: a novel oligonucleotide synthesized by interferon-treated L cell extracts. Cell 13:565-572.
    • (1978) Cell , vol.13 , pp. 565-572
    • Clemmens, M.J.1    Williams, B.R.G.2
  • 10
    • 0022377506 scopus 로고
    • Apoptosis, lymphotoxicity and the containment of virus infections
    • Clouston, W. M., and J. F. R. Kerr. 1985. Apoptosis, lymphotoxicity and the containment of virus infections. Med. Hypotheses 18:399-404.
    • (1985) Med. Hypotheses , vol.18 , pp. 399-404
    • Clouston, W.M.1    Kerr, J.F.R.2
  • 11
    • 0029056951 scopus 로고
    • Potential roles of apoptosis in viral pathogenesis
    • Collins, M. 1995. Potential roles of apoptosis in viral pathogenesis. Am. J. Crit. Care Med. 152:S20-S24.
    • (1995) Am. J. Crit. Care Med. , vol.152
    • Collins, M.1
  • 12
    • 0030992545 scopus 로고    scopus 로고
    • A double-stranded RNA-activated protein kinase-dependent pathway mediating stress-induced apoptosis
    • Der, S. D., Y. L. Yang, C. Weissmann, and B. R. G. Williams. 1997. A double-stranded RNA-activated protein kinase-dependent pathway mediating stress-induced apoptosis. Proc. Natl. Acad. Sci. USA 94:3279-3283.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 3279-3283
    • Der, S.D.1    Yang, Y.L.2    Weissmann, C.3    Williams, B.R.G.4
  • 13
    • 0031555633 scopus 로고    scopus 로고
    • Inducible expression of the 2-5A synthetase/RNase-L system results in inhibition of vaccinia virus replication
    • Diaz-Guerra, M., C. Rivas, and M. Esteban. 1997. Inducible expression of the 2-5A synthetase/RNase-L system results in inhibition of vaccinia virus replication. Virology 227:220-228.
    • (1997) Virology , vol.227 , pp. 220-228
    • Diaz-Guerra, M.1    Rivas, C.2    Esteban, M.3
  • 14
    • 0028909072 scopus 로고
    • 2-5A-dependent RNase molecules dimerize during activation by 2-5A
    • Dong, B., and R. H. Silverman. 1995. 2-5A-dependent RNase molecules dimerize during activation by 2-5A. J. Biol. Chem. 270:4133-4137.
    • (1995) J. Biol. Chem. , vol.270 , pp. 4133-4137
    • Dong, B.1    Silverman, R.H.2
  • 16
    • 0019794540 scopus 로고
    • Interferon action: RNA cleavage pattern of a (2′-5′)oligoadenylate-dependent endonuclease
    • Floyd-Smith, G., E. Slattery, and P. Lengyel. 1981. Interferon action: RNA cleavage pattern of a (2′-5′)oligoadenylate-dependent endonuclease. Science 212:1020-1032.
    • (1981) Science , vol.212 , pp. 1020-1032
    • Floyd-Smith, G.1    Slattery, E.2    Lengyel, P.3
  • 17
    • 0022423216 scopus 로고
    • Various rat adult tissues express only one major species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family
    • Fort, P. M., L. Marty, M. Piechaczyk, S. el Sabrouty, C. Dani, P. Janteur, and M. Blanchard. 1985. Various rat adult tissues express only one major species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family. Nucleic Acids Res. 13:1431-1442.
    • (1985) Nucleic Acids Res. , vol.13 , pp. 1431-1442
    • Fort, P.M.1    Marty, L.2    Piechaczyk, M.3    El Sabrouty, S.4    Dani, C.5    Janteur, P.6    Blanchard, M.7
  • 18
    • 0000458098 scopus 로고
    • Control of the decay of labile protooncogene and cytokine mRNAs
    • J. G. Belasco and G. Brawerman (ed.), Academic Press, San Diego, Calif.
    • Greenberg, M. E., and J. G. Belasco. 1993. Control of the decay of labile protooncogene and cytokine mRNAs, p. 199-218. In J. G. Belasco and G. Brawerman (ed.), Control of messenger RNA stability. Academic Press, San Diego, Calif.
    • (1993) Control of Messenger RNA Stability , pp. 199-218
    • Greenberg, M.E.1    Belasco, J.G.2
  • 19
    • 0026057917 scopus 로고
    • Interferon action: Binding of viral RNA to the 40-kilodalton 2′-5′-oligoadenylate synthetase in interferon-treated HeLa cells infected with encephalomyocarditis virus
    • Gribaudo G., D. Lembo, G. Cavallo, S. Landolfo and P. Lengyel. 1991. Interferon action: binding of viral RNA to the 40-kilodalton 2′-5′-oligoadenylate synthetase in interferon-treated HeLa cells infected with encephalomyocarditis virus. J. Virol. 65:1748-1757.
    • (1991) J. Virol. , vol.65 , pp. 1748-1757
    • Gribaudo, G.1    Lembo, D.2    Cavallo, G.3    Landolfo, S.4    Lengyel, P.5
  • 20
    • 0028904540 scopus 로고
    • Encephalomyocarditis viruses with short poly(C) tracts are more virulent than their mengovirus counterparts
    • Hahn, H., and A. C. Palmenberg. 1995. Encephalomyocarditis viruses with short poly(C) tracts are more virulent than their mengovirus counterparts. J. Virol. 69:2697-2699.
    • (1995) J. Virol. , vol.69 , pp. 2697-2699
    • Hahn, H.1    Palmenberg, A.C.2
  • 21
    • 2642626741 scopus 로고    scopus 로고
    • Unpublished results
    • Hassel, B. A. Unpublished results.
    • Hassel, B.A.1
  • 22
    • 0027270867 scopus 로고
    • A dominant negative mutant of 2-5A-dependent RNase suppresses antiproliferative and antiviral effects of interferon
    • Hassel, B. A., A. Zhou, C. Sotomayor, A. Maran, and R. H. Silverman. 1993. A dominant negative mutant of 2-5A-dependent RNase suppresses antiproliferative and antiviral effects of interferon. EMBO J. 12:3297-3304.
    • (1993) EMBO J. , vol.12 , pp. 3297-3304
    • Hassel, B.A.1    Zhou, A.2    Sotomayor, C.3    Maran, A.4    Silverman, R.H.5
  • 24
    • 0017372188 scopus 로고
    • Synthesis of low molecular weight inhibitor of protein synthesis with enzyme from interferon-treated cells
    • Hovanessian, A. G., R. E. Brown, and I. M. Kerr. 1977. Synthesis of low molecular weight inhibitor of protein synthesis with enzyme from interferon-treated cells. Nature 268:537-539.
    • (1977) Nature , vol.268 , pp. 537-539
    • Hovanessian, A.G.1    Brown, R.E.2    Kerr, I.M.3
  • 25
    • 0000520727 scopus 로고
    • Virus interference. I. The interferon
    • Isaacs, A., and J. Lindenmann. 1957. Virus interference. I. The interferon. Proc. R. Soc. Lond. B 147:258-267.
    • (1957) Proc. R. Soc. Lond. B , vol.147 , pp. 258-267
    • Isaacs, A.1    Lindenmann, J.2
  • 26
    • 0023655215 scopus 로고
    • Purification and characterization of a 2′-phosphodiesterase from bovine spleen
    • Johnston, M. I., and W. G. Hearl. 1987. Purification and characterization of a 2′-phosphodiesterase from bovine spleen. J. Biol. Chem. 262:8377-8382.
    • (1987) J. Biol. Chem. , vol.262 , pp. 8377-8382
    • Johnston, M.I.1    Hearl, W.G.2
  • 27
    • 0029887863 scopus 로고    scopus 로고
    • An overview of the interferon system: Signal transduction and mechanisms of action
    • Kalvakolanu, D. V., and E. C. Borden. 1996. An overview of the interferon system: signal transduction and mechanisms of action. Cancer Investig. 14: 25-53.
    • (1996) Cancer Investig. , vol.14 , pp. 25-53
    • Kalvakolanu, D.V.1    Borden, E.C.2
  • 28
    • 0013683658 scopus 로고
    • pppA2′p5′A2′p5′A: An inhibitor of protein synthesis synthesized with an enzyme fraction from interferon-treated cells
    • Kerr, I. M., and R. E. Brown. 1978. pppA2′p5′A2′p5′A: an inhibitor of protein synthesis synthesized with an enzyme fraction from interferon-treated cells. Proc. Natl. Acad. Sci. USA 75:256-260.
    • (1978) Proc. Natl. Acad. Sci. USA , vol.75 , pp. 256-260
    • Kerr, I.M.1    Brown, R.E.2
  • 30
    • 0019200844 scopus 로고
    • Radioimmune, radiobinding and HPLC analysis of 2-5A and related oligonucleotides from intact cells
    • Knight, M., P. J. Cayley, R. H. Silverman, D. H. Wreschner, C. S. Gilbert, R. E. Brown, and I. M. Kerr. 1980. Radioimmune, radiobinding and HPLC analysis of 2-5A and related oligonucleotides from intact cells. Nature 288: 189-192.
    • (1980) Nature , vol.288 , pp. 189-192
    • Knight, M.1    Cayley, P.J.2    Silverman, R.H.3    Wreschner, D.H.4    Gilbert, C.S.5    Brown, R.E.6    Kerr, I.M.7
  • 31
    • 0022406374 scopus 로고
    • Independent regulation of ppp(A2′p)nA-dependent RNase in NIH3T3, clone 1 cells by growth arrest and interferon treatment
    • Krause, D., A. Panet, G. Arad, C. W. Dieffenbach, and R. H. Silverman. 1985. Independent regulation of ppp(A2′p)nA-dependent RNase in NIH3T3, clone 1 cells by growth arrest and interferon treatment. J. Biol. Chem. 260: 9501-9507.
    • (1985) J. Biol. Chem. , vol.260 , pp. 9501-9507
    • Krause, D.1    Panet, A.2    Arad, G.3    Dieffenbach, C.W.4    Silverman, R.H.5
  • 32
    • 0023748276 scopus 로고
    • Studies on the role of the 2′-5′-oligoadenylate synthetase-RNase L pathway in beta interferon-mediated inhibition of encephalomyocarditis virus replication
    • Kumar, R., D. Choubey, P. Lengyel, and G. C. Sen. 1988. Studies on the role of the 2′-5′-oligoadenylate synthetase-RNase L pathway in beta interferon-mediated inhibition of encephalomyocarditis virus replication. J. Virol. 62: 3175-3181.
    • (1988) J. Virol. , vol.62 , pp. 3175-3181
    • Kumar, R.1    Choubey, D.2    Lengyel, P.3    Sen, G.C.4
  • 33
    • 0028290902 scopus 로고
    • The interferon-induced double-stranded RNA-activated protein kinase induces apoptosis
    • Lee, S. B., and M. Esteban. 1994. The interferon-induced double-stranded RNA-activated protein kinase induces apoptosis. Virology 199:491-496.
    • (1994) Virology , vol.199 , pp. 491-496
    • Lee, S.B.1    Esteban, M.2
  • 34
    • 0026674886 scopus 로고
    • Differential display of eucaryotic messenger RNA by means of the polymerase chain reaction
    • Liang, P., and A. B. Pardee. 1992. Differential display of eucaryotic messenger RNA by means of the polymerase chain reaction. Science 257:967-971.
    • (1992) Science , vol.257 , pp. 967-971
    • Liang, P.1    Pardee, A.B.2
  • 35
    • 0020700023 scopus 로고
    • Transcriptionally active c-myc oncogene is contained within NIARD, a DNA sequence associated with chromosome translocations in B-cell neoplasia
    • Marcu, K. B., L. J. Harris, L. W. Stanton, J. Erikson, R. Watt, and C. M. Croce. 1983. Transcriptionally active c-myc oncogene is contained within NIARD, a DNA sequence associated with chromosome translocations in B-cell neoplasia. Proc. Natl. Acad. Sci. USA 80:519-523.
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 519-523
    • Marcu, K.B.1    Harris, L.J.2    Stanton, L.W.3    Erikson, J.4    Watt, R.5    Croce, C.M.6
  • 36
    • 0020620746 scopus 로고
    • Molecular cloning and sequence of partial cDNA for interferon-induced (2′-5′)oligo(A) synthetase mRNA from human cells
    • Merlin, G., J. Chebath, P. Benech, R. Metz, and M. Revel. 1983. Molecular cloning and sequence of partial cDNA for interferon-induced (2′-5′)oligo(A) synthetase mRNA from human cells. Proc. Natl. Acad. Sci. USA 80:4904-4908.
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 4904-4908
    • Merlin, G.1    Chebath, J.2    Benech, P.3    Metz, R.4    Revel, M.5
  • 37
    • 0026929934 scopus 로고
    • Constitutive expression of human double-stranded RNA-activated p68 kinase in murine cells mediates phosphorylation of eukaryotic initiation factor 2 and partial resistance to encephalomyocarditis virus growth
    • Meurs, E. F., Y. Watanabe, S. Kadereit, G. N. Barber, M. G. Katze, K. Chong, B. R. G. Williams, and A. G. Hovanessian. 1992. Constitutive expression of human double-stranded RNA-activated p68 kinase in murine cells mediates phosphorylation of eukaryotic initiation factor 2 and partial resistance to encephalomyocarditis virus growth. J. Virol. 66:5805-5814.
    • (1992) J. Virol. , vol.66 , pp. 5805-5814
    • Meurs, E.F.1    Watanabe, Y.2    Kadereit, S.3    Barber, G.N.4    Katze, M.G.5    Chong, K.6    Williams, B.R.G.7    Hovanessian, A.G.8
  • 38
    • 0018763477 scopus 로고
    • Mechanism for discrimination between viral and host mRNA in interferon-treated cells
    • Nilsen, T. W., and C. Baglioni. 1979. Mechanism for discrimination between viral and host mRNA in interferon-treated cells. Proc. Natl. Acad. Sci. USA 76:2600-2604.
    • (1979) Proc. Natl. Acad. Sci. USA , vol.76 , pp. 2600-2604
    • Nilsen, T.W.1    Baglioni, C.2
  • 39
    • 0019775615 scopus 로고
    • Double-stranded RNA causes synthesis of 2′,5′-oligo(A) and degradation of messenger RNA in interferon-treated cells
    • Nilsen, T. W., P. A. Maroney, and C. Baglioni. 1981. Double-stranded RNA causes synthesis of 2′,5′-oligo(A) and degradation of messenger RNA in interferon-treated cells. J. Biol. Chem. 256:7806-7811.
    • (1981) J. Biol. Chem. , vol.256 , pp. 7806-7811
    • Nilsen, T.W.1    Maroney, P.A.2    Baglioni, C.3
  • 40
    • 0020055037 scopus 로고
    • Synthesis of (2′,5′)oligoadenylate and activation of an endoribonuclease in interferon-treated HeLa cells infected with reovirus
    • Nilsen, T. W., P. A. Maroney, and C. Baglioni. 1982. Synthesis of (2′,5′)oligoadenylate and activation of an endoribonuclease in interferon-treated HeLa cells infected with reovirus. J. Virol. 42:1039-1045.
    • (1982) J. Virol. , vol.42 , pp. 1039-1045
    • Nilsen, T.W.1    Maroney, P.A.2    Baglioni, C.3
  • 41
    • 0027722486 scopus 로고
    • Mx proteins: GTPases involved in the interferon-induced antiviral state
    • Pavlovic, J., A. Schroder, A. Blank, F. Pitossi, and P. Staeheli. 1993. Mx proteins: GTPases involved in the interferon-induced antiviral state. Ciba Found. Symp. 176:233-243.
    • (1993) Ciba Found. Symp. , vol.176 , pp. 233-243
    • Pavlovic, J.1    Schroder, A.2    Blank, A.3    Pitossi, F.4    Staeheli, P.5
  • 42
    • 0024831453 scopus 로고
    • Constitutive expression of a 2′,5′-oligoadenylate synthetase cDNA results in increased antiviral activity and growth suppression
    • Rysiecki, G., D. R. Gewert, and B. R. G. Williams. 1989. Constitutive expression of a 2′,5′-oligoadenylate synthetase cDNA results in increased antiviral activity and growth suppression. J. Interferon Res. 9:649-657.
    • (1989) J. Interferon Res. , vol.9 , pp. 649-657
    • Rysiecki, G.1    Gewert, D.R.2    Williams, B.R.G.3
  • 44
    • 0022101989 scopus 로고
    • Human 2-5a synthetase: Characterization of a novel cDNA and corresponding gene structure
    • Saunders, M. E., D. R. Gewert, M. E. Tugwell, M. McMahon, and B. R. G. Williams. 1985. Human 2-5A synthetase: characterization of a novel cDNA and corresponding gene structure. EMBO J. 4:1761-1768.
    • (1985) EMBO J. , vol.4 , pp. 1761-1768
    • Saunders, M.E.1    Gewert, D.R.2    Tugwell, M.E.3    McMahon, M.4    Williams, B.R.G.5
  • 45
    • 0029069145 scopus 로고
    • Transcriptional responses to polypeptide ligands: The JAK-STAT pathway
    • Schindler, C., and J. E. Darnell. 1995. Transcriptional responses to polypeptide ligands: the JAK-STAT pathway. Annu. Rev. Biochem. 64:621-651.
    • (1995) Annu. Rev. Biochem. , vol.64 , pp. 621-651
    • Schindler, C.1    Darnell, J.E.2
  • 46
    • 0026739463 scopus 로고
    • The interferon system - A bird's eye view of its biochemistry
    • Sen, G. C., and P. Lengyel. 1992. The interferon system - a bird's eye view of its biochemistry. J. Biol. Chem. 267:5017-5020.
    • (1992) J. Biol. Chem. , vol.267 , pp. 5017-5020
    • Sen, G.C.1    Lengyel, P.2
  • 47
    • 0003095520 scopus 로고    scopus 로고
    • 2-5a dependent RNase L: A regulated endoribo-nuclease in the interferon system
    • G. D'Alessio 2nd J. F. Riordan (ed.), Academic Press, New York, N.Y.
    • Silverman, R. H. 1997. 2-5A dependent RNase L: a regulated endoribo-nuclease in the interferon system, p. 515-551. In G. D'Alessio 2nd J. F. Riordan (ed.), Ribonucleases: structure and function. Academic Press, New York, N.Y.
    • (1997) Ribonucleases: Structure and Function , pp. 515-551
    • Silverman, R.H.1
  • 51
    • 0027067061 scopus 로고
    • Intracellular localization of poliovirus RNA by in situ hybridization at the ultrastructural level using single-stranded riboprobes
    • Troxler, M., D. Egger, T. Pfister, and K. Bienz. 1992. Intracellular localization of poliovirus RNA by in situ hybridization at the ultrastructural level using single-stranded riboprobes. Virology 191:687-697.
    • (1992) Virology , vol.191 , pp. 687-697
    • Troxler, M.1    Egger, D.2    Pfister, T.3    Bienz, K.4
  • 52
    • 0022017441 scopus 로고
    • Analogue inhibitor of 2-5A action: Effect on the interferon-mediated inhibition of encephalomyocarditis virus replication
    • Watling, D., H. T. Serafinowska, C. B. Reese, and I. M. Kerr. 1985. Analogue inhibitor of 2-5A action: effect on the interferon-mediated inhibition of encephalomyocarditis virus replication. EMBO J. 4:431-436.
    • (1985) EMBO J. , vol.4 , pp. 431-436
    • Watling, D.1    Serafinowska, H.T.2    Reese, C.B.3    Kerr, I.M.4
  • 53
    • 0025797722 scopus 로고
    • Transcriptional regulation of interferon-stimulated genes
    • Williams, B. R. G. 1991. Transcriptional regulation of interferon-stimulated genes. Eur. J. Biochem. 200:1-11.
    • (1991) Eur. J. Biochem. , vol.200 , pp. 1-11
    • Williams, B.R.G.1
  • 54
    • 0018706198 scopus 로고
    • Natural occurrence of 2-5A in interferon-treated EMC virus-infected L cells
    • Williams, B. R. G., R. R. Golgher, R. E. Brown, C. S. Gilbert, and I. M. Kerr. 1979. Natural occurrence of 2-5A in interferon-treated EMC virus-infected L cells. Nature 282:582-586.
    • (1979) Nature , vol.282 , pp. 582-586
    • Williams, B.R.G.1    Golgher, R.R.2    Brown, R.E.3    Gilbert, C.S.4    Kerr, I.M.5
  • 55
    • 0019389403 scopus 로고
    • Ribosomal RNA cleavage, nuclease activation and 2-5A (ppp(A2′p)nA) in interferon-treated cells
    • Wreschner, D. H., T. C. James, R. H. Silverman, and I. M. Kerr. 1981. Ribosomal RNA cleavage, nuclease activation and 2-5A (ppp(A2′p)nA) in interferon-treated cells. Nucleic Acids Res. 9:1571-1581.
    • (1981) Nucleic Acids Res. , vol.9 , pp. 1571-1581
    • Wreschner, D.H.1    James, T.C.2    Silverman, R.H.3    Kerr, I.M.4
  • 57
    • 0027510449 scopus 로고
    • Expression cloning of 2-5a dependent RNase: A uniquely regulated mediator of interferon action
    • Zhou, A., B. A. Hassel, and R. H. Silverman. 1993. Expression cloning of 2-5A dependent RNase: a uniquely regulated mediator of interferon action. Cell 72:1-20.
    • (1993) Cell , vol.72 , pp. 1-20
    • Zhou, A.1    Hassel, B.A.2    Silverman, R.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.