The type III effectors NieE and NleB from enteropathogenic E. coli and Ospz from shigella block nuclear translocation of NF-κB p65

PLoS Pathogens

Volumn 6, Issue 5, 2010, Pages 1-16

  Newton, Hayley J ^a   Pearson, Jaclyn S ^a   Badea, Luminita ^a   Kelly, Michelle ^a   Lucas, Mark ^b   Holloway, Gavan ^a   Wagstaff, Kylie M ^c   Dunstone, Michelle A ^c   Sloan, Joan ^a   Whisstock, James C ^c   Kaper, James B ^d   Robins Browne, Roy M ^a   Jans, David A ^c   Frankel, Gad ^e   Phillips, Alan D ^b   Coulson, Barbara S ^a   Hartland, Elizabeth L ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^c MONASH UNIVERSITY   (Australia)

^d UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^e IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; I KAPPA B; INTERLEUKIN 1BETA; INTERLEUKIN 8; PROTEIN NLEB; PROTEIN NLEE; PROTEIN OSPZ; PROTEIN P50; STAT1 PROTEIN; STAT2 PROTEIN; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR REL; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ESCHERICHIA COLI PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; NLEE PROTEIN, E COLI; STAT1 PROTEIN, HUMAN; STAT2 PROTEIN, HUMAN; VIRULENCE FACTOR;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL NUCLEUS; CONTROLLED STUDY; ENTEROPATHOGENIC ESCHERICHIA COLI; HOST CELL; HOST PATHOGEN INTERACTION; HUMAN; HUMAN CELL; INTESTINE EPITHELIUM CELL; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN MOTIF; PROTEIN TRANSPORT; SHIGELLA BOYDII; SHIGELLA FLEXNERI; SIGNAL TRANSDUCTION; TYPE III SECRETION SYSTEM; ACTIVE TRANSPORT; CELL STRAIN CACO 2; ESCHERICHIA COLI INFECTION; ESCHERICHIA COLI O157; GENETICS; HELA CELL; IMMUNOLOGY; INTESTINE MUCOSA; METABOLISM; MICROBIOLOGY; PATHOGENICITY; PHYSIOLOGY; SHIGELLOSIS; TRANSCRIPTION INITIATION; VIRULENCE;

BACTERIA (MICROORGANISMS); SHIGELLA; SHIGELLA BOYDII; SHIGELLA FLEXNERI; SHIGELLA FLEXNERI 2A;

ACTIVE TRANSPORT, CELL NUCLEUS; CACO-2 CELLS; DYSENTERY, BACILLARY; ESCHERICHIA COLI INFECTIONS; ESCHERICHIA COLI O157; ESCHERICHIA COLI PROTEINS; HELA CELLS; HUMANS; I-KAPPA B PROTEINS; INTERLEUKIN-8; INTESTINAL MUCOSA; NF-KAPPA B P50 SUBUNIT; PROTO-ONCOGENE PROTEINS C-REL; RNA, MESSENGER; SHIGELLA BOYDII; SHIGELLA FLEXNERI; STAT1 TRANSCRIPTION FACTOR; STAT2 TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RELA; TRANSCRIPTIONAL ACTIVATION; VIRULENCE; VIRULENCE FACTORS;

EID: 77954066144     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1000898     Document Type: Article

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