-
3
-
-
35548956927
-
Small cell lung cancer: Have we made any progress over the last 25 years?
-
DOI 10.1634/theoncologist.12-9-1096
-
Lally BE, Urbanic JJ, Blackstock AW, Miller AA and Perry MC: Small cell lung cancer: have we made any progress over the last 25 years? Oncologist 12: 1096-1104, 2007. (Pubitemid 350007021)
-
(2007)
Oncologist
, vol.12
, Issue.9
, pp. 1096-1104
-
-
Lally, B.E.1
Urbanic, J.J.2
Blackstock, A.W.3
Miller, A.A.4
Perry, M.C.5
-
4
-
-
70649099227
-
Twenty-seven years of phase III trials for patients with extensive disease small-cell lung cancer: Disappointing results
-
Oze I, Hotta K, Kiura K, et al: Twenty-seven years of phase III trials for patients with extensive disease small-cell lung cancer: disappointing results. PLoS One 4: e7835, 2009.
-
(2009)
PLoS One
, vol.4
-
-
Oze, I.1
Hotta, K.2
Kiura, K.3
-
5
-
-
51649095569
-
The Aurora kinase family in cell division and cancer
-
Vader G and Lens SM: The Aurora kinase family in cell division and cancer. Biochim Biophys Acta 1786: 60-72, 2008.
-
(2008)
Biochim Biophys Acta
, vol.1786
, pp. 60-72
-
-
Vader, G.1
Lens, S.M.2
-
6
-
-
84873721726
-
Aurora A kinase (AURKA) in normal and pathological cell division
-
Nikonova AS, Astsaturov I, Serebriiskii IG, Dunbrack RL Jr and Golemis EA: Aurora A kinase (AURKA) in normal and pathological cell division. Cell Mol Life Sci 70: 661-687, 2013.
-
(2013)
Cell Mol Life Sci
, vol.70
, pp. 661-687
-
-
Nikonova, A.S.1
Astsaturov, I.2
Serebriiskii, I.G.3
Dunbrack Jr., R.L.4
Golemis, E.A.5
-
7
-
-
0038341158
-
The Aurora kinases: Role in cell transformation and tumorigenesis
-
DOI 10.1023/A:1023789416385
-
Katayama H, Brinkley WR and Sen S: The Aurora kinases: role in cell transformation and tumorigenesis. Cancer Metastasis Rev 22: 451-464, 2003. (Pubitemid 36791899)
-
(2003)
Cancer and Metastasis Reviews
, vol.22
, Issue.4
, pp. 451-464
-
-
Katayama, H.1
Brinkley, W.R.2
Sen, S.3
-
8
-
-
0345304925
-
AuroraA overexpression overrides the mitotic spindle checkpoint triggered by nocodazole, a microtubule destabilizer
-
DOI 10.1038/sj.onc.1206873
-
Jiang Y, Zhang Y, Lees E and Seghezzi W: AuroraA overexpression overrides the mitotic spindle checkpoint triggered by nocodazole, a microtubule destabilizer. Oncogene 22: 8293-8301, 2003. (Pubitemid 37485522)
-
(2003)
Oncogene
, vol.22
, Issue.51
, pp. 8293-8301
-
-
Jiang, Y.1
Zhang, Y.2
Lees, E.3
Seghezzi, W.4
-
9
-
-
0037586498
-
AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol
-
DOI 10.1016/S1535-6108(02)00235-0
-
Anand S, Penrhyn-Lowe S and Venkitaraman AR: AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol. Cancer Cell 3: 51-62, 2003. (Pubitemid 37443890)
-
(2003)
Cancer Cell
, vol.3
, Issue.1
, pp. 51-62
-
-
Anand, S.1
Penrhyn-Lowe, S.2
Venkitaraman, A.R.3
-
10
-
-
0031714080
-
Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation
-
DOI 10.1038/2496
-
Zhou H, Kuang J, Zhong L, et al: Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation. Nat Genet 20: 189-193, 1998. (Pubitemid 28455454)
-
(1998)
Nature Genetics
, vol.20
, Issue.2
, pp. 189-193
-
-
Zhou, H.1
Kuang, J.2
Zhong, L.3
Kuo, W.-L.4
Gray, J.W.5
Sahin, A.6
Brinkley, B.R.7
Sen, S.8
-
11
-
-
33751085368
-
Overexpression of aurora kinase A in mouse mammary epithelium induces genetic instability preceding mammary tumor formation
-
DOI 10.1038/sj.onc.1209707, PII 1209707
-
Wang X, Zhou YX, Qiao W, et al: Overexpression of aurora kinase A in mouse mammary epithelium induces genetic instability preceding mammary tumor formation. Oncogene 25: 7148-7158, 2006. (Pubitemid 44764184)
-
(2006)
Oncogene
, vol.25
, Issue.54
, pp. 7148-7158
-
-
Wang, X.1
Zhou, Y.-X.2
Qiao, W.3
Tominaga, Y.4
Ouchi, M.5
Ouchi, T.6
Deng, C.-X.7
-
12
-
-
84856389509
-
RNA-based therapeutics: Current progress and future prospects
-
Burnett JC and Rossi JJ: RNA-based therapeutics: current progress and future prospects. Chem Biol 19: 60-71, 2012.
-
(2012)
Chem Biol
, vol.19
, pp. 60-71
-
-
Burnett, J.C.1
Rossi, J.J.2
-
13
-
-
82755161958
-
Silencing disease genes in the laboratory and the clinic
-
Watts JK and Corey DR: Silencing disease genes in the laboratory and the clinic. J Pathol 226: 365-379, 2012.
-
(2012)
J Pathol
, vol.226
, pp. 365-379
-
-
Watts, J.K.1
Corey, D.R.2
-
14
-
-
58749104364
-
The promises and pitfalls of RNA-interference-based therapeutics
-
Castanotto D and Rossi JJ: The promises and pitfalls of RNA-interference-based therapeutics. Nature 457: 426-433, 2009.
-
(2009)
Nature
, vol.457
, pp. 426-433
-
-
Castanotto, D.1
Rossi, J.J.2
-
15
-
-
79751485564
-
The many faces of RNAi
-
Ketting RF: The many faces of RNAi. Dev Cell 20: 148-161, 2011.
-
(2011)
Dev Cell
, vol.20
, pp. 148-161
-
-
Ketting, R.F.1
-
16
-
-
84860540912
-
Biomarkers for small cell lung cancer: Neuroendocrine, epithelial and circulating tumour cells
-
Stovold R, Blackhall F, Meredith S, Hou J, Dive C and White A: Biomarkers for small cell lung cancer: neuroendocrine, epithelial and circulating tumour cells. Lung Cancer 76: 263-268, 2012.
-
(2012)
Lung Cancer
, vol.76
, pp. 263-268
-
-
Stovold, R.1
Blackhall, F.2
Meredith, S.3
Hou, J.4
Dive, C.5
White, A.6
-
17
-
-
0032100685
-
A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers
-
DOI 10.1093/emboj/17.11.3052
-
Bischoff JR, Anderson L, Zhu Y, et al: A homologue of Drosophila aurora kinase is oncogenic and amplified in human cancers. EMBO J 17: 3052-3065, 1998. (Pubitemid 28254378)
-
(1998)
EMBO Journal
, vol.17
, Issue.11
, pp. 3052-3065
-
-
Bischoff, J.R.1
Anderson, L.2
Zhu, Y.3
Mossie, K.4
Ng, L.5
Souza, B.6
Schryver, B.7
Flanagan, P.8
Clairvoyant, F.9
Ginther, C.10
Chan, C.S.M.11
Novotny, M.12
Slamon, D.J.13
Plowman, G.D.14
-
18
-
-
33748991178
-
Aurora kinase A messenger RNA overexpression is correlated with tumor progression and shortened survival in head and neck squamous cell carcinoma
-
DOI 10.1158/1078-0432.CCR-05-1650
-
Reiter R, Gais P, Jütting U, et al: Aurora kinase A messenger RNA overexpression is correlated with tumor progression and shortened survival in head and neck squamous cell carcinoma. Clin Cancer Res 12: 5136-5141, 2006. (Pubitemid 44453341)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.17
, pp. 5136-5141
-
-
Reiter, R.1
Gais, P.2
Jutting, U.3
Steuer-Vogt, M.K.4
Pickhard, A.5
Bink, K.6
Rauser, S.7
Lassmann, S.8
Hofler, H.9
Werner, M.10
Walch, A.11
-
19
-
-
78649908015
-
Aurora-A overexpression and aneuploidy predict poor outcome in serous ovarian carcinoma
-
Lassus H, Staff S, Leminen A, Isola J and Butzow R: Aurora-A overexpression and aneuploidy predict poor outcome in serous ovarian carcinoma. Gynecol Oncol 120: 11-17, 2011.
-
(2011)
Gynecol Oncol
, vol.120
, pp. 11-17
-
-
Lassus, H.1
Staff, S.2
Leminen, A.3
Isola, J.4
Butzow, R.5
-
20
-
-
73549095963
-
shRNA technology: Investigating Ras-dependent cancer
-
Stein EV, Price DK and Figg WD: shRNA technology: investigating Ras-dependent cancer. Cancer Biol Ther 8: 1798-1799, 2009.
-
(2009)
Cancer Biol Ther
, vol.8
, pp. 1798-1799
-
-
Stein, E.V.1
Price, D.K.2
Figg, W.D.3
-
21
-
-
66149091940
-
A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene
-
Luo J, Emanuele MJ, Li D, et al: A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene. Cell 137: 835-848, 2009.
-
(2009)
Cell
, vol.137
, pp. 835-848
-
-
Luo, J.1
Emanuele, M.J.2
Li, D.3
-
22
-
-
0037134020
-
A system for stable expression of short interfering RNAs in mammalian cells
-
DOI 10.1126/science.1068999
-
Brummelkamp TR, Bernards R and Agami R: A system for stable expression of short interfering RNAs in mammalian cells. Science 296: 550-553, 2002. (Pubitemid 34408678)
-
(2002)
Science
, vol.296
, Issue.5567
, pp. 550-553
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
23
-
-
73549102150
-
Stable knockdown of Aurora-A by vector-based RNA interference in human esophageal squamous cell carcinoma cell line inhibits tumor cell proliferation, invasion and enhances apoptosis
-
Wang X, Dong L, Xie J, Tong T and Zhan Q: Stable knockdown of Aurora-A by vector-based RNA interference in human esophageal squamous cell carcinoma cell line inhibits tumor cell proliferation, invasion and enhances apoptosis. Cancer Biol Ther 8: 1852-1859, 2009.
-
(2009)
Cancer Biol Ther
, vol.8
, pp. 1852-1859
-
-
Wang, X.1
Dong, L.2
Xie, J.3
Tong, T.4
Zhan, Q.5
-
24
-
-
84861117630
-
Overexpression of Aurora-A enhances invasion and matrix metalloproteinase-2 expression in esophageal squamous cell carcinoma cells
-
Wang X, Lu N, Niu B, Chen X, Xie J and Cheng N: Overexpression of Aurora-A enhances invasion and matrix metalloproteinase-2 expression in esophageal squamous cell carcinoma cells. Mol Cancer Res 10: 588-596, 2012.
-
(2012)
Mol Cancer Res
, vol.10
, pp. 588-596
-
-
Wang, X.1
Lu, N.2
Niu, B.3
Chen, X.4
Xie, J.5
Cheng, N.6
-
25
-
-
77953711842
-
Aurora kinase A promotes ovarian tumorigenesis through dysregulation of the cell cycle and suppression of BRCA2
-
Yang G, Chang B, Yang F, et al: Aurora kinase A promotes ovarian tumorigenesis through dysregulation of the cell cycle and suppression of BRCA2. Clin Cancer Res 16: 3171-3181, 2010.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 3171-3181
-
-
Yang, G.1
Chang, B.2
Yang, F.3
-
26
-
-
69249230769
-
Mammalian cell-cycle regulation: Several Cdks, numerous cyclins and diverse compensatory mechanisms
-
Satyanarayana A and Kaldis P: Mammalian cell-cycle regulation: several Cdks, numerous cyclins and diverse compensatory mechanisms. Oncogene 28: 2925-2939, 2009.
-
(2009)
Oncogene
, vol.28
, pp. 2925-2939
-
-
Satyanarayana, A.1
Kaldis, P.2
-
27
-
-
0024573538
-
The cdc2 kinase is a nuclear protein that is essential for mitosis in mammalian cells
-
DOI 10.1016/0092-8674(89)90914-8
-
Riabowol K, Draetta G, Brizuela L, Vandre D and Beach D: The cdc2 kinase is a nuclear protein that is essential for mitosis in mammalian cells. Cell 57: 393-401, 1989. (Pubitemid 19126273)
-
(1989)
Cell
, vol.57
, Issue.3
, pp. 393-401
-
-
Riabowol, K.1
Draetta, G.2
Brizuela, L.3
Vandre, D.4
Beach, D.5
-
28
-
-
3042734502
-
Phosphorylation of CDC25B by Aurora-A at the centrosome contributes to the G2-M transition
-
DOI 10.1242/jcs.01108
-
Dutertre S, Cazales M, Quaranta M, et al: Phosphorylation of CDC25B by Aurora-A at the centrosome contributes to the G2-M transition. J Cell Sci 117: 2523-2531, 2004. (Pubitemid 38877848)
-
(2004)
Journal of Cell Science
, vol.117
, Issue.12
, pp. 2523-2531
-
-
Dutertre, S.1
Cazales, M.2
Quaranta, M.3
Froment, C.4
Trabut, V.5
Dozier, C.6
Mirey, G.7
Bouche, J.-P.8
Theis-Febvre, N.9
Schmitt, E.10
Monsarrat, B.11
Prigent, C.12
Ducommun, B.13
-
29
-
-
80051761743
-
The role of Bcl-2 and its pro-survival relatives in tumourigenesis and cancer therapy
-
Kelly PN and Strasser A: The role of Bcl-2 and its pro-survival relatives in tumourigenesis and cancer therapy. Cell Death Differ 18: 1414-1424, 2011.
-
(2011)
Cell Death Differ
, vol.18
, pp. 1414-1424
-
-
Kelly, P.N.1
Strasser, A.2
-
30
-
-
79954672344
-
Bufalin and cinobufagin induce apoptosis of human hepatocellular carcinoma cells via Fas- and mitochondria-mediated pathways
-
Qi F, Inagaki Y, Gao B, et al: Bufalin and cinobufagin induce apoptosis of human hepatocellular carcinoma cells via Fas- and mitochondria-mediated pathways. Cancer Sci 102: 951-958, 2011.
-
(2011)
Cancer Sci
, vol.102
, pp. 951-958
-
-
Qi, F.1
Inagaki, Y.2
Gao, B.3
-
31
-
-
20444486559
-
An inhibitor of Bcl-2 family proteins induces regression of solid tumours
-
DOI 10.1038/nature03579
-
Oltersdorf T, Elmore SW, Shoemaker AR, et al: An inhibitor of Bcl-2 family proteins induces regression of solid tumours. Nature 435: 677-681, 2005. (Pubitemid 40825512)
-
(2005)
Nature
, vol.435
, Issue.7042
, pp. 677-681
-
-
Oltersdorf, T.1
Elmore, S.W.2
Shoemaker, A.R.3
Armstrong, R.C.4
Augeri, D.J.5
Belli, B.A.6
Bruncko, M.7
Deckwerth, T.L.8
Dinges, J.9
Hajduk, P.J.10
Joseph, M.K.11
Kitada, S.12
Korsmeyer, S.J.13
Kunzer, A.R.14
Letai, A.15
Li, C.16
Mitten, M.J.17
Nettesheim, D.G.18
Ng, S.19
Nimmer, P.M.20
O'Connor, J.M.21
Oleksijew, A.22
Petros, A.M.23
Reed, J.C.24
Shen, W.25
Tahir, S.K.26
Thompson, C.B.27
Tomaselli, K.J.28
Wang, B.29
Wendt, M.D.30
Zhang, H.31
Fesik, S.W.32
Rosenberg, S.H.33
more..
-
32
-
-
80051547187
-
Plasminogen K5 activates mitochondrial apoptosis pathway in endothelial cells by regulating Bak and Bcl-xL subcellular distribution
-
Gu X, Yao Y, Cheng R, et al: Plasminogen K5 activates mitochondrial apoptosis pathway in endothelial cells by regulating Bak and Bcl-xL subcellular distribution. Apoptosis 16: 846-855, 2011.
-
(2011)
Apoptosis
, vol.16
, pp. 846-855
-
-
Gu, X.1
Yao, Y.2
Cheng, R.3
|