Rapid detection of DNMT3A R882 mutations in hematologic malignancies using a novel bead-based suspension assay with BNA(NC) probes

PLoS ONE

Volumn 9, Issue 6, 2014, Pages

  Shivarov, Velizar ^a   Ivanova, Milena ^b   Naumova, Elissaveta ^b  

^a National Hematology Hospital   (Bulgaria)

^b UNIVERSITY HOSPITAL ALEXANDROVSKA   (Bulgaria)

Author keywords

[No Author keywords available]

Indexed keywords

DNA METHYLTRANSFERASE 3A; GENOMIC DNA; DNA; DNA (CYTOSINE 5) METHYLTRANSFERASE; DNA PROBE; MICROSPHERE;

ACUTE GRANULOCYTIC LEUKEMIA; ALLELE; ARTICLE; CANCER PROGNOSIS; CODON; GENE MUTATION; HEMATOLOGIC MALIGNANCY; HUMAN; HYBRIDIZATION; MAJOR CLINICAL STUDY; MISSENSE MUTATION; MUTANT; PHILADELPHIA 1 CHROMOSOME; QUANTITATIVE ANALYSIS; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SENSITIVITY ANALYSIS; SENSITIVITY AND SPECIFICITY; WILD TYPE; AMINO ACID SUBSTITUTION; DNA PROBE; GENETICS; HEMATOLOGIC DISEASE; HUMAN GENOME; METABOLISM; MOLECULAR GENETICS; MUTATION; NUCLEIC ACID HYBRIDIZATION; NUCLEOTIDE SEQUENCE; PROCEDURES; RECEIVER OPERATING CHARACTERISTIC; STANDARD; STATISTICAL MODEL;

ALLELES; AMINO ACID SUBSTITUTION; BASE SEQUENCE; DNA; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA MUTATIONAL ANALYSIS; DNA PROBES; GENOME, HUMAN; HEMATOLOGIC NEOPLASMS; HUMANS; LINEAR MODELS; MICROSPHERES; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEIC ACID HYBRIDIZATION; REFERENCE STANDARDS; ROC CURVE;

EID: 84902668907     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0099769     Document Type: Article

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