A DNMT3A mutation common in AML exhibits dominant-negative effects in murine ES cells

Blood

Volumn 122, Issue 25, 2013, Pages 4086-4089

  Kim, Soo Jin ^a   Zhao, Hongbo ^a   Hardikar, Swanand ^a   Singh, Anup Kumar ^a   Goodell, Margaret A ^b   Chen, Taiping ^a,c  

^a UNIVERSITY OF TEXAS   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; DNA (CYTOSINE 5) METHYLTRANSFERASE;

ACUTE MYELOID LEUKEMIA; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; COS-7 CELL LINE; DNA METHYLATION; EMBRYO; ENZYME ACTIVITY; ENZYME INHIBITION; MOUSE; MOUSE EMBRYONIC STEM CELL; MUTATION; NONHUMAN; PRIORITY JOURNAL; WILD TYPE; ACUTE GRANULOCYTIC LEUKEMIA; AMINO ACID SUBSTITUTION; ANIMAL; BIOSYNTHESIS; CHLOROCEBUS AETHIOPS; COS 1 CELL LINE; DOMINANT GENE; EMBRYONIC STEM CELL; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; MISSENSE MUTATION; MUTANT MOUSE STRAIN; PATHOLOGY;

AMINO ACID SUBSTITUTION; ANIMALS; CERCOPITHECUS AETHIOPS; COS CELLS; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; EMBRYONIC STEM CELLS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, LEUKEMIC; GENES, DOMINANT; LEUKEMIA, MYELOID, ACUTE; MICE; MICE, MUTANT STRAINS; MUTATION, MISSENSE;

EID: 84893437787     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2013-02-483487     Document Type: Article

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