Mutations in DNA methyltransferase (DNMT3A) observed in acute myeloid leukemia patients disrupt processive methylation

Journal of Biological Chemistry

Volumn 287, Issue 37, 2012, Pages 30941-30951

  Holz Schietinger, Celeste ^a   Matje, Doug M ^a   Reich, Norbert O ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE MYELOID LEUKEMIA; DNA METHYLATION; DNA METHYLTRANSFERASES; KEY REGULATORS; ONCOGENESIS; TETRAMERIZATION; TETRAMERS; TUMORIGENESIS;

ALKYLATION; DIAGNOSIS; DISEASES; GENE EXPRESSION; OLIGOMERS;

METHYLATION;

DNA METHYLTRANSFERASE 3A;

ACUTE GRANULOCYTIC LEUKEMIA; ARTICLE; CANCER PATIENT; CARCINOGENESIS; CPG ISLAND; DISEASE COURSE; DNA METHYLATION; DNA SEQUENCE; DNA STRUCTURE; DNMT3A GENE; EPIGENETICS; GENE ACTIVITY; GENE FUNCTION; GENE MUTATION; GENETIC REGULATION; HUMAN; NUCLEOTIDE SEQUENCE; ONCOGENE; PRIORITY JOURNAL;

ADULT; AMINO ACID SUBSTITUTION; CELL TRANSFORMATION, NEOPLASTIC; CPG ISLANDS; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; FEMALE; HUMANS; LEUKEMIA, MYELOID, ACUTE; MALE; MUTATION, MISSENSE;

EID: 84866077973     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.366625     Document Type: Article

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