Cripto-1 expression in glioblastoma multiforme

Brain Pathology

Volumn 24, Issue 4, 2014, Pages 360-370

  Pilgaard, Linda ^a   Mortensen, Joachim Høg ^a   Henriksen, Michael ^a   Olesen, Pia ^a   Sørensen, Preben ^a   Laursen, Rene ^a   Vyberg, Mogens ^a   Agger, Ralf ^a   Zachar, Vladimir ^b   Moos, Torben ^b   Duroux, Meg ^a  

^a AALBORG UNIVERSITY   (Denmark)

^b AALBORG UNIVERSITY HOSPITAL   (Denmark)

Author keywords

CR 1; endothelial proliferation; glioblastoma multiforme; microvasculature; plasma biomarker; tumor niche

Indexed keywords

BIOLOGICAL MARKER; CRIPTO 1 PROTEIN; GROWTH FACTOR; UNCLASSIFIED DRUG; CD31 ANTIGEN; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; SIGNAL PEPTIDE; TDGF1 PROTEIN, HUMAN; TUMOR PROTEIN;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD ANALYSIS; CANCER GRADING; CANCER GROWTH; CANCER SURVIVAL; CLINICAL ARTICLE; CONTROLLED STUDY; EMBRYO DEVELOPMENT; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GLIOBLASTOMA; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; MOUSE; NONHUMAN; OVERALL SURVIVAL; POLYMERASE CHAIN REACTION; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; WESTERN BLOTTING; ANIMAL; BRAIN TUMOR; CANCER TRANSPLANTATION; COHORT ANALYSIS; METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL LINE; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; ANIMALS; ANTIGENS, CD31; BIOLOGICAL MARKERS; BLOTTING, WESTERN; BRAIN NEOPLASMS; CELL LINE, TUMOR; COHORT STUDIES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GLIOBLASTOMA; GPI-LINKED PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MICE; MIDDLE AGED; NEOPLASM PROTEINS; NEOPLASM TRANSPLANTATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 84902662835     PISSN: 10156305     EISSN: 17503639     Source Type: Journal    
DOI: 10.1111/bpa.12131     Document Type: Article

References (60)

1. Adkins HB, Bianco C, Schiffer SG, Rayhorn P, Zafari M, Cheung AE, et al. (2003) Antibody blockade of the Cripto CFC domain suppresses tumor cell growth in vivo. J Clin Invest 112: 575-587.
2. Beier D, Hau P, Proescholdt M, Lohmeier A, Wischhusen J, Oefner PJ, et al. (2007) CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles. Cancer Res 67: 4010-4015.
3. Bianco C, Castro NP, Baraty C, Rollman K, Held N, Rangel MC, et al. (2013) Regulation of human Cripto-1 expression by nuclear receptors and DNA promoter methylation in human embryonal and breast cancer cells. J Cell Physiol 228: 1174-1188.
4. Bianco C, Cotten C, Lonardo E, Strizzi L, Baraty C, Mancino M, et al. (2009) Cripto-1 is required for hypoxia to induce cardiac differentiation of mouse embryonic stem cells. Am J Pathol 175: 2146-2158.
5. Bianco C, Rangel MC, Castro NP, Nagaoka T, Rollman K, Gonzales M, Salomon DS, (2010) Role of Cripto-1 in stem cell maintenance and malignant progression. Am J Pathol 177: 532-540.
6. Bianco C, Salomon DS, (2009) Human Cripto-1 as a target for a cancer vaccine: WO2008040759. Expert Opin Ther Pat 19: 141-144.
7. Bianco C, Strizzi L, Ebert A, Chang C, Rehman A, Normanno N, et al. (2005) Role of human cripto-1 in tumor angiogenesis. J Natl Cancer Inst 97: 132-141.
8. Bianco C, Strizzi L, Mancino M, Rehman A, Hamada S, Watanabe K, et al. (2006) Identification of cripto-1 as a novel serologic marker for breast and colon cancer. Clin Cancer Res 12: 5158-5164.
9. Birner P, Piribauer M, Fischer I, Gatterbauer B, Marosi C, Ambros PF, et al. (2003) Vascular patterns in glioblastoma influence clinical outcome and associate with variable expression of angiogenic proteins: evidence for distinct angiogenic subtypes. Brain Pathol 13: 133-143.
10. Brandt R, Normanno N, Gullick WJ, Lin JH, Harkins R, Schneider D, et al. (1994) Identification and biological characterization of an epidermal growth factor-related protein: cripto-1. J Biol Chem 269: 17320-17328.
11. Brognaro E, (2011) A theory and a model to understand glioblastoma development both in the bulk and in the microinfiltrated brain parenchyma. Neurochem Res 36: 2145-2154.
12. Bruick RK, (2003) Oxygen sensing in the hypoxic response pathway: regulation of the hypoxia-inducible transcription factor. Genes Dev 17: 2614-2623.
13. Camphausen K, Purow B, Sproull M, Scott T, Ozawa T, Deen DF, Tofilon PJ, (2005) Influence of in vivo growth on human glioma cell line gene expression: convergent profiles under orthotopic conditions. Proc Natl Acad Sci U S A 102: 8287-8292.
14. Chou CH, Lieu AS, Wu CH, Chang LK, Loh JK, Lin RC, et al. (2010) Differential expression of hedgehog signaling components and Snail/E-cadherin in human brain tumors. Oncol Rep 24: 1225-1232.
15. Christensen K, Schrøder HD, Kristensen BW, (2011) CD133(+) niches and single cells in glioblastoma have different phenotypes. J Neurooncol 104: 129-143.
16. Ciccodicola A, Dono R, Obici S, Simeone A, Zollo M, Persico MG, (1989) Molecular characterization of a gene of the "EGF family" expressed in undifferentiated human NTERA2 teratocarcinoma cells. EMBO J 8: 1987-1991.
17. Clement V, Dutoit V, Marino D, Dietrich PY, Radovanovic I, (2009) Limits of CD133 as a marker of glioma self-renewing cells. Int J Cancer 125: 244-248.
18. D'Antonio A, Losito S, Pignata S, Grassi M, Perrone F, De Luca A, et al. (2002) Transforming growth factor alpha, amphiregulin and cripto-1 are frequently expressed in advanced human ovarian carcinomas. Int J Oncol 21: 941-948.
19. De Luca A, Arra C, D'Antonio A, Casamassimi A, Losito S, Ferraro P, et al. (2000) Simultaneous blockage of different EGF-like growth factors results in efficient growth inhibition of human colon carcinoma xenografts. Oncogene 19: 5863-5871.
20. DeAngelis LM, (2001) Brain tumors. N Engl J Med 344: 114-123.
21. Ding J, Yang L, Yan YT, Chen A, Desai N, Wynshaw-Boris A, Shen MM, (1998) Cripto is required for correct orientation of the anterior-posterior axis in the mouse embryo. Nature 395: 702-707.
22. Elias MC, Tozer KR, Silber JR, Mikheeva S, Deng M, Morrison RS, et al. (2005) TWIST is expressed in human gliomas and promotes invasion. Neoplasia 7: 824-837.
23. Eramo A, Ricci-Vitiani L, Zeuner A, Pallini R, Lotti F, Sette G, et al. (2006) Chemotherapy resistance of glioblastoma stem cells. Cell Death Differ 13: 1238-1241.
24. Freije WA, Castro-Vargas FE, Fang Z, Horvath S, Cloughesy T, Liau LM, et al. (2004) Gene expression profiling of gliomas strongly predicts survival. Cancer Res 64: 6503-6510.
25. Friess H, Yamanaka Y, Buchler M, Kobrin MS, Tahara E, Korc M, (1994) Cripto, a member of the epidermal growth factor family, is over-expressed in human pancreatic cancer and chronic pancreatitis. Int J Cancer 56: 668-674.
26. Fuchs IB, Lichtenegger W, Buehler H, Henrich W, Stein H, Kleine-Tebbe A, Schaller G, (2002) The prognostic significance of epithelial-mesenchymal transition in breast cancer. Anticancer Res 22 (6A): 3415-3419.
27. Gao X, Xu Z, (2008) Mechanisms of action of angiogenin. Acta Biochim Biophys Sin (Shanghai) 40: 619-624.
28. Goda N, Ryan HE, Khadivi B, McNulty W, Rickert RC, Johnson RS, (2003) Hypoxia-inducible factor 1alpha is essential for cell cycle arrest during hypoxia. Mol Cell Biol 23: 359-369.
29. Gong YP, Yarrow PM, Carmalt HL, Kwun SY, Kennedy CW, Lin BP, et al. (2007) Overexpression of Cripto and its prognostic significance in breast cancer: a study with long-term survival. Eur J Surg Oncol 33: 438-443.
30. Hamada S, Watanabe K, Hirota M, Bianco C, Strizzi L, Mancino M, et al. (2007) beta-Catenin/TCF/LEF regulate expression of the short form human Cripto-1. Biochem Biophys Res Commun 355: 240-244.
31. Hermansen SK, Christensen KG, Jensen SS, Kristensen BW, (2011) Inconsistent immunohistochemical expression patterns of four different CD133 antibody clones in glioblastoma. J Histochem Cytochem 59: 391-407.
32. Kang MK, Kang SK, (2007) Tumorigenesis of chemotherapeutic drug-resistant cancer stem-like cells in brain glioma. Stem Cells Dev 16: 837-847.
33. Lee CC, Jan HJ, Lai JH, Ma HI, Hueng DY, Lee YC, et al. (2010) Nodal promotes growth and invasion in human gliomas. Oncogene 29: 3110-3123.
34. Li P, Zhou C, Xu L, Xiao H, (2013) Hypoxia enhances stemness of cancer stem cells in glioblastoma: an in vitro study. Int J Med Sci 10: 399-407.
35. Li Z, Bao S, Wu Q, Wang H, Eyler C, Sathornsumetee S, et al. (2009) Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells. Cancer Cell 15: 501-513.
36. Mancino M, Strizzi L, Wechselberger C, Watanabe K, Gonzales M, Hamada S, et al. (2008) Regulation of human Cripto-1 gene expression by TGF-beta1 and BMP-4 in embryonal and colon cancer cells. J Cell Physiol 215: 192-203.
37. Mikheeva SA, Mikheev AM, Petit A, Beyer R, Oxford RG, Khorasani L, et al. (2010) Rostomily RC TWIST1 promotes invasion through mesenchymal change in human glioblastoma. Mol Cancer 9: 194.
38. Phillips HS, Kharbanda S, Chen R, Forrest WF, Soriano RH, Wu TD, et al. (2006) Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis. Cancer Cell 9: 157-173.
39. Plate KH, Risau W, (1995) Angiogenesis in malignant gliomas. Glia 15: 339-347.
40. Saeki T, Stromberg K, Qi CF, Gullick WJ, Tahara E, Normanno N, et al. (1992) Differential immunohistochemical detection of amphiregulin and cripto in human normal colon and colorectal tumors. Cancer Res 52: 3467-3473.
41. Sakariassen PO, Prestegarden L, Wang J, Skaftnesmo KO, Mahesparan R, Molthoff C, et al. (2006) Angiogenesis-independent tumor growth mediated by stem-like cancer cells. Proc Natl Acad Sci U S A 103: 16466-16471.
42. Saloman DS, Bianco C, Ebert AD, Khan NI, De Santis M, Normanno N, et al. (2000) The EGF-CFC family: novel epidermal growth factor-related proteins in development and cancer. Endocr Relat Cancer 7: 199-226.
43. Sandberg CJ, Altschuler G, Jeong J, Stromme KK, Stangeland B, Murrell W, et al. (2013) Comparison of glioma stem cells to neural stem cells from the adult human brain identifies dysregulated Wnt-signaling and a fingerprint associated with clinical outcome. Exp Cell Res 319: 2230-2243.
44. Seidel S, Garvalov BK, Wirta V, von Stechow L, Schanzer A, Meletis K, et al. (2010) A hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2 alpha. Brain 133 (Pt 4): 983-995.
45. Shmelkov SV, Butler JM, Hooper AT, Hormigo A, Kushner J, Milde T, et al. (2008) CD133 expression is not restricted to stem cells, and both CD133+ and CD133- metastatic colon cancer cells initiate tumors. J Clin Invest 118: 2111-2120.
46. Singh SK, Clarke ID, Terasaki M, Bonn VE, Hawkins C, Squire J, Dirks PB, (2003) Identification of a cancer stem cell in human brain tumors. Cancer Res 63: 5821-5828.
47. Singh SK, Hawkins C, Clarke ID, Squire JA, Bayani J, Hide T, et al. (2004) Identification of human brain tumour initiating cells. Nature 432: 396-401.
48. Soda Y, Marumoto T, Friedmann-Morvinski D, Soda M, Liu F, Michiue H, et al. (2011) From the cover: feature article: transdifferentiation of glioblastoma cells into vascular endothelial cells. Proc Natl Acad Sci U S A 108: 4274-4280.
49. Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, et al. (2005) A human protein-protein interaction network: a resource for annotating the proteome. Cell 122: 957-968.
50. Stupp R, Mason WP, van den Bent MJ, Weller M, Fisher B, Taphoorn MJ, et al. (2005) Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 352: 987-996.
51. Su AI, Wiltshire T, Batalov S, Lapp H, Ching KA, Block D, et al. (2004) A gene atlas of the mouse and human protein-encoding transcriptomes. Proc Natl Acad Sci U S A 101: 6062-6067.
52. Tso CL, Shintaku P, Chen J, Liu Q, Liu J, Chen Z, et al. (2006) Primary glioblastomas express mesenchymal stem-like properties. Mol Cancer Res 4: 607-619.
53. Vajkoczy P, Farhadi M, Gaumann A, Heidenreich R, Erber R, Wunder A, et al. (2002) Microtumor growth initiates angiogenic sprouting with simultaneous expression of VEGF, VEGF receptor-2, and angiopoietin-2. J Clin Invest 109: 777-785.
54. Valente V, Teixeira SA, Neder L, Okamoto OK, Oba-Shinjo SM, Marie SK, et al. (2009) Selection of suitable housekeeping genes for expression analysis in glioblastoma using quantitative RT-PCR. BMC Mol Biol 10: 17.
55. Wang R, Chadalavada K, Wilshire J, Kowalik U, Hovinga KE, Geber A, et al. (2010) Glioblastoma stem-like cells give rise to tumour endothelium. Nature 468: 829-833.
56. Wechselberger C, Ebert AD, Bianco C, Khan NI, Sun Y, Wallace-Jones B, et al. (2001) Cripto-1 enhances migration and branching morphogenesis of mouse mammary epithelial cells. Exp Cell Res 266: 95-105.
57. Wu C, Orozco C, Boyer J, Leglise M, Goodale J, Batalov S, et al. (2009) BioGPS: an extensible and customizable portal for querying and organizing gene annotation resources. Genome Biol 10: R130.
58. Xu C, Liguori G, Persico MG, Adamson ED, (1999) Abrogation of the Cripto gene in mouse leads to failure of postgastrulation morphogenesis and lack of differentiation of cardiomyocytes. Development 126: 483-494.
59. Xue C, Plieth D, Venkov C, Xu C, Neilson EG, (2003) The gatekeeper effect of epithelial-mesenchymal transition regulates the frequency of breast cancer metastasis. Cancer Res 63: 3386-3394.
60. Zhong XY, Zhang LH, Jia SQ, Shi T, Niu ZJ, Du H, et al. (2008) Positive association of up-regulated Cripto-1 and down-regulated E-cadherin with tumour progression and poor prognosis in gastric cancer. Histopathology 52: 560-568.