Abrogation of the Cripto gene in mouse leads to failure of postgastrulation morphogenesis and lack of differentiation of cardiomyocytes

Development

Volumn 126, Issue 3, 1999, Pages 483-494

  Xu, Chunhui ^a   Liguori, Giovanna ^b   Persico, M Graziella ^b   Adamson, Eileen D ^a  

^a BURNHAM INSTITUTE   (United States)

^b INSTITUTE OF GENETICS AND BIOPHYSICS ADRIANO BUZZATI TRAVERSO   (Italy)

Author keywords

Cardiac myosin; Gastrulation; Gene targeting; Homologous recombination; Mesoderm; Mouse; Neuroepithelium; Visceral endoderm

Indexed keywords

ATRIAL NATRIURETIC FACTOR; GROWTH FACTOR; MYOSIN HEAVY CHAIN; MYOSIN LIGHT CHAIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DEVELOPMENTAL GENETICS; ECTODERM; EMBRYO; ENDODERM; GASTRULATION; GENE; HEART MUSCLE CELL; MESODERM; MORPHOGENESIS; MOUSE; MOUSE MUTANT; MUSCLE DEVELOPMENT; NEUROEPITHELIUM; NONHUMAN; PLACENTA; PRIORITY JOURNAL; YOLK SAC;

ALLELES; ANIMALS; BIOLOGICAL MARKERS; CELL DIFFERENTIATION; CHIMERA; CULTURE TECHNIQUES; EPIDERMAL GROWTH FACTOR; FIBROBLASTS; GASTRULA; GENOTYPE; GROWTH SUBSTANCES; HEART; HOMOZYGOTE; MEMBRANE GLYCOPROTEINS; MESODERM; MICE; MICE, INBRED C57BL; MORPHOGENESIS; MYOCARDIUM; NEOPLASM PROTEINS; NEOVASCULARIZATION, PHYSIOLOGIC; PHENOTYPE;

ANIMALIA; MAMMALIA;

EID: 0033000369     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. Adamson, E. D., Deller, M. J. and Warshaw, J. B. (1981). Functional EGF receptors on embryonic cells. Nature 291, 656-659.
2. Auerbach, R., Gilligan, B., Lu, L. S. and Wang, S. J. (1997). Cell interactions in the mouse yolk sac - vasculogenesis and hematopoiesis. J. Cell. Physiol. 173, 202-205.
3. Baldassarre, G., Bianco, C., Tortora, G., Ruggiero, A., Moasser, M., Dmitrovsky, E., Bianco, A. R. and Ciardiello, F. (1996). Transfection with a CRIPTO anti-sense plasmid suppresses endogenous CRIPTO expression and inhibits transformation in a human embryonal carcinoma cell line. Int J Cancer 66, 538-543.
4. Biben, C. and Harvey, R. P. (1997). Homeodomain factor Nkx2-5 controls left/right asymmetric expression of bHLH gene eHAND during murine heart development. Genes Dev. 11, 1367-1369.
5. Bradley, A. (1987). Production and analysis of chimaeric mice. In Teratocarcinomas and Embryonic Stem Cells: a Practical Approach (ed. E. J. Robertson), pp. 113-151. Oxford: IRL Press.
6. Brandt, R., Normanno, N., Gullick, W. J., Lin, J.-H., Harkins, R., Scheider, D., Jones, B.-W., Ciardiello, F., Persico, M. G., Armenante, F., Kim, N. and Salomon, D. S. (1994). Identification and biological characterization of an epidermal growth factor-related protein: Cripto-1. J. Biol. Chem. 269, 17320-17328.
7. Ciccodicola, A., Dono, R., Obici, S., Simeone, A., Zollo, M. and Persico, M. G. (1989). Molecular characterization of a gene of the 'EGF family' expressed in undifferentiated human NTERA2 teratocarcinoma cells. EMBO J. 8, 1987-1991.
8. Cserjesi, P., Brown, D., Lyons, G. E. and Olson, E. N. (1995). Expression of the novel basic helix-loop-helix gene eHAND in neural crest derivatives and extraembryonic membranes during mouse development. Dev. Biol. 170, 664-678.
9. Ding, J., Yang, Y., Yan, Y.-T., Chan, A., Desai, N., Wynshaw-Boris, A. and Shen, M. M. (1998). Cripto is required for correct orientation of the anterior-posterior axis in the mouse embryo. Nature 395, 702-707.
10. Dono, R., Montuori, N., Rocchi, M., De Ponti-Zilli, L., Ciccodicola, A. and Persico, M. G. (1991). Isolation and characterization of the CRIPTO autosomal gene and its X-linked related sequence. Amer. J. Hum. Genet. 49, 555-565.
11. Dono, R., Scalera, L., Pacifico, F., Acampora, D., Persico, M. G. and Simeone, A. (1993). The murine cripto gene: expression during mesoderm induction and early heart morphogenesis. Development 118, 1157-1168.
12. Drab, M., Haller, H., Bychkov, R., Erdmann, B., Lindschau, C., Haase, H., Morano, I., Luft, F. C. and Wobus, A. M. (1997). From totipotent embryonic stem cells to spontaneously contracting smooth muscle cells: a retinoic acid and db-cAMP in vitro differentiation model. FASEB J. 11, 905-915.
13. Dziadek, M. A. and Adamson, E. D. (1978). Localization and synthesis of alphafetoprotein in post-implantation mouse embryos. J. Embryol. Exp. Morph. 43, 289-313.
14. Edmondson, D. G., Lyons, G. E., Martin, J. F. and Olson, E. N. (1994). Mef2 gene expression marks the cardiac and skeletal muscle lineages during mouse embryogenesis. Development 120, 1251-1263.
15. Fishman, M. C. and Chien, K. R. (1997). Fashioning the venebrate heart: earliest embryonic decisions. Development 124, 2099-2117.
16. Grover, A., Oshima, R. G. and Adamson, E. D. (1983). Epithelial layer formation in differentiating aggregates of F9 embryonal carcinoma cells. J. Cell. Biol. 96, 1690-1696.
17. Hogan, B. L. M., Costantini, F. and Lacy, E. (1993). Manipulating the Mouse Embryo: A Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratories.
18. Hummler, E., Barker, P., Gatzy, J., Beermann, F., Verdumo, C., Schmidt, A., Boucher, R. and Rossier, B. C. (1996). Early death due to defective neonatal lung liquid clearance in alpha-ENaC-deficient mice. Nat. Genet. 12, 325-328.
19. Johnson, S. E., Rothstein, J. L. and Knowles, B. B. (1994). Expression of epidermal growth factor family gene members in early mouse development. Dev. Dyn. 201, 216-226.
20. Kannan, S., De Santis, M., Lohmeyer, M., Riese, D. J., Smith, G. H., Hynes, N., Seno, M., Brandt, R., Bianco, C., Persico, G., Kenney, N., Normanno, N., Martinez-Lacaci, I., Ciardiello, F., Stern, D. F., Gullick, W. J. and Salomon, D. S. (1997). Cripto enhances the tyrosine phosphorylation of She and activates mitogen-activated protein kinase (MAPK) in mammary epithelial cells. J. Biol. Chem. 272, 3330-3335.
21. Kinoshita, N., Minshull, J. and Kirschner, M. W. (1995). The identification of two novel ligands of the FGF receptor by a yeast screening method and their activity in Xenopus development. Cell 83, 621-630.
22. Kubalak, S. W., Miller-Hance, W. C., O'Brien, T. X., Dyson, E. and Chien, K. R. (1994). Chamber specification of atrial myosin light chain-2 expression precedes septation during murine cardiogenesis. J. Biol. Chem. 269, 16961-16970.
23. Liguori, G., Tucci, M., Montuori, N., Dono, R., Lago, C. T., Pacifico, F., Armenante, F. and Persico, M. G. (1996) Characterization of the mouse Tdgf1 gene and Tdgf pseudogenes. Mamm. Genome 7, 344-348.
24. Lin, Q., Schwarz, J., Bucana, C. and Olson, E. N. (1997). Control of mouse cardiac morphogenesis and myogenesis by transcription factor Mef2c. Science 276, 1404-1407.
25. Lints, T. J., Parsons, L. M., Hartley, L., Lyons, I. and Harvey, R. P. (1993). Nkx-2.5: a novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants. Development 119, 419-431.
26. Lyons, G. E. (1996). Vertebrate heart development. Curr. Opin. Genet. Dev. 6, 454-460.
27. Mansfield, P. J. and Suchard, S. J. (1994). Thrombospondin promotes chemotaxis and haptotaxis of human peripheral blood monocytes. J. Immunol. 153, 4219-4229.
28. Martin, J. F., Schwarz, J. J. and Olson, E. N. (1993). Myocyte enhancer factor (MEF) 2C: a tissue-restricted member of the MEF-2 family of transcription factors. Proc. Natl. Acad. Sci. USA 90, 5282-5286.
29. Miller-Hance, W. C., LaCorbiere, M., Fuller, S. J., Evans, S. M., Lyons, G., Schmidt, C., Robbins, J. and Chien, K. R. (1993). In vitro chamber specification during embryonic stem cell cardiogenesis. Expression of the ventricular myosin light chain-2 gene is independent of heart tube formation. J. Biol. Chem. 268, 25244-25252.
30. Molkentin, J. D., Lin, Q., Duncan, S. A. and Olson, E. N. (1997). Requirement Of the Transcription Factor Gata4 For Heart Tube Formation and Ventral Morphogenesis. Genes Dev. 11, 1061-1072.
31. Niemeyer, C. C., Persico, M. G. and Adamson, E. D. (1998). Cripto: roles in mammary cell growth, survival, differentiation and transformation. Cell Death Differ. 5, 440-449.
32. Olson, E. N. (1997). Things are developing in cardiology. Circ. Res. 80, 604-606.
33. Olson, E. N. and Srivastava, D. (1996). Molecular pathways controlling heart development. Science 272, 671-676.
34. Risau, W., Sariola, H., Zerwes, H. G., Sasse, J., Ekblom, P., Kemler, R. and Doetschman, T. (1988). Vasculogenesis and angiogenesis in embryonic-stem-cell-derived embryoid bodies. Development 102, 471-478.
35. Robbins, J., Gulick, J., Sanchez, A., Howles, P. and Doetschman, T. (1990). Mouse embryonic stem cells express the cardiac myosin heavy chain genes during development in vitro. J. Biol. Chem. 265, 11905-9.
36. Robertson, E. J. (1987). Embryo-derived stem cell lines. In Teratocarcinomas and Embryonic Stem Cells: a Practical Approach (ed. E. J. Robertson), pp. 71-112. Oxford: IRL Press, Inc.
37. Shalaby, F., Rossant, J., Yamaguchi, T. P., Gertsenstein, M., Wu, X. F., Breitman, M. L. and Schuh, A. C. (1995). Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice. Nature 376, 62-66.
38. Shen, M. M., Wang, H. and Leder, P. (1997). A differential display strategy identifies Cryptic, a novel EGF-related gene expressed in the axial and lateral mesoderm during mouse gastrulation. Development 124, 429-442.
39. Srivastava, D., Thomas, T., Lin, Q., Kirby, M. L., Brown, D. and Olson, E. N. (1997). Regulation Of Cardiac Mesodermal and Neural Crest Development By the Bhlh Transcription Factor, dHand. Nature Genetics 16, 154-160.
40. Vittet, D., Prandini, M. H., Berthier, R., Schweitzer, A., Martin-Sisteron, H., Uzan, G. and Dejana, E. (1996). Embryonic stem cells differentiate in vitro to endothelial cells through successive maturation steps. Blood 88, 3424-3431.
41. Xu, C., Liguori, G., Adamson, E. D. and Persico, M. G. (1998). Cardiac differentiation is blocked in embryonic stem cells lacking Cripto-1. Dev. Biol. 196, 237-247.
42. Zhang, J., Talbot, W. S. and Schier, A. F. (1998). Positional cloning identifies zebrafish one-eyed pinhead as a permissive EGF-related ligand required during gastrulation. Cell 92, 241-251.