Carpesium macrocephalum attenuates lipopolysaccharide-induced inflammation in macrophages by regulating the NF-κB/IκB-α, Akt, and STAT signaling pathways

American Journal of Chinese Medicine

Volumn 41, Issue 4, 2013, Pages 927-943

  Koppula, Sushruta ^a   Kim, Wan Jae ^a   Jiang, Jun ^a   Shim, Do Wan ^a   Oh, Na Hyun ^a   Kim, Tack Joong ^b   Kang, Tae Bong ^a   Lee, Kwang Ho ^a  

^a Konkuk University   (South Korea)

^b Yonsei University Wonju   (South Korea)

Author keywords

Akt; Carpesium macrocephalum; Inflammation; Macrophage; NF B; STAT

Indexed keywords

ACETIC ACID; ANTIINFECTIVE AGENT; CARPESIUM MACROCEPHALUM EXTRACT; CYCLOOXYGENASE 2; I KAPPA B ALPHA; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; PLANT EXTRACT; PROSTAGLANDIN E2; PROTEIN KINASE B; STAT1 PROTEIN; STAT3 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ATTENUATION; BLOOD VESSEL PERMEABILITY; CARPESIUM MACROCEPHALUM; CELL VIABILITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DOWN REGULATION; DRUG CYTOTOXICITY; IN VITRO STUDY; IN VIVO STUDY; MACROPHAGE; MALE; MEDICINAL PLANT; MOUSE; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

ANIMALS; ASTERACEAE; CAPILLARY PERMEABILITY; DINOPROSTONE; ENDOTOXINS; I-KAPPA B PROTEINS; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; NF-KAPPA B; NITRIC OXIDE; PLANT EXTRACTS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; STAT TRANSCRIPTION FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84881121101     PISSN: 0192415X     EISSN: None     Source Type: Journal    
DOI: 10.1142/S0192415X13500626     Document Type: Article

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