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Volumn 197, Issue 1, 2009, Pages 239-245

Ginsenosides attenuate kainic acid-induced synaptosomal oxidative stress via stimulation of adenosine A2A receptors in rat hippocampus

Author keywords

Adenosine A2A receptor; Ginsenosides; Hippocampus; Kainate; Oxidative stress; Synaptosome

Indexed keywords

8 (3 CHLOROSTYRYL)CAFFEINE; 8 CYCLOPENTYLTHEOPHYLLINE; ADENOSINE A2A RECEPTOR; ADRENERGIC RECEPTOR BLOCKING AGENT; ALLOXAZINE; GINSENOSIDE; KAINIC ACID; UNCLASSIFIED DRUG;

EID: 57649210760     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2008.08.038     Document Type: Article
Times cited : (22)

References (40)
  • 1
    • 2942642480 scopus 로고    scopus 로고
    • Enhancement of central dopaminergic activity in the kainate model of temporal lobe epilepsy: implication for the mechanism of epileptic psychosis
    • Ando N., Morimoto K., Watanabe T., Ninomiya T., and Suwaki H. Enhancement of central dopaminergic activity in the kainate model of temporal lobe epilepsy: implication for the mechanism of epileptic psychosis. Neuropsychopharmacology 29 (2004) 1251-1258
    • (2004) Neuropsychopharmacology , vol.29 , pp. 1251-1258
    • Ando, N.1    Morimoto, K.2    Watanabe, T.3    Ninomiya, T.4    Suwaki, H.5
  • 2
    • 0344549853 scopus 로고    scopus 로고
    • Ginseng pharmacology: multiple constituents and multiple actions
    • Attele A.S., Wu J.A., and Yuan C.S. Ginseng pharmacology: multiple constituents and multiple actions. Biochem. Pharmacol. 58 (1999) 1685-1693
    • (1999) Biochem. Pharmacol. , vol.58 , pp. 1685-1693
    • Attele, A.S.1    Wu, J.A.2    Yuan, C.S.3
  • 3
    • 0031018190 scopus 로고    scopus 로고
    • Kainate-evoked release of adenosine from the hippocampus of the anaesthetised rat: possible involvement of free radicals
    • Carswell H.V., Graham D.I., and Stone T.W. Kainate-evoked release of adenosine from the hippocampus of the anaesthetised rat: possible involvement of free radicals. J. Neurochem. 68 (1997) 240-247
    • (1997) J. Neurochem. , vol.68 , pp. 240-247
    • Carswell, H.V.1    Graham, D.I.2    Stone, T.W.3
  • 4
    • 0032403733 scopus 로고    scopus 로고
    • Progressive neurodegeneration after intracerebroventricular kainic acid administration in rats: implication for schizophrenia
    • Csernansky J.G., Csernansky C.A., Kogelman L., Montgomery E.M., and Bardgett M.E. Progressive neurodegeneration after intracerebroventricular kainic acid administration in rats: implication for schizophrenia. Biol. Psychiatry 44 (1998) 1143-1150
    • (1998) Biol. Psychiatry , vol.44 , pp. 1143-1150
    • Csernansky, J.G.1    Csernansky, C.A.2    Kogelman, L.3    Montgomery, E.M.4    Bardgett, M.E.5
  • 5
    • 0034064253 scopus 로고    scopus 로고
    • 3H]GABA release from rat hippocampus nerve terminals
    • 3H]GABA release from rat hippocampus nerve terminals. Neuropharmacology 39 7 (2000) 1156-1167
    • (2000) Neuropharmacology , vol.39 , Issue.7 , pp. 1156-1167
    • Cunha, R.A.1    Ribeiro, J.A.2
  • 6
    • 0030829317 scopus 로고    scopus 로고
    • Enhancement of basal and pentylenetetrazol (PTZ)-stimulated dopamine release in the brain of feely moving rats by PTZ-induced kindling
    • Dazzi L., Serra M., Porceddu M.L., Sanna A., Chessa M.F., and Biggio G. Enhancement of basal and pentylenetetrazol (PTZ)-stimulated dopamine release in the brain of feely moving rats by PTZ-induced kindling. Synapse 26 (1997) 351-358
    • (1997) Synapse , vol.26 , pp. 351-358
    • Dazzi, L.1    Serra, M.2    Porceddu, M.L.3    Sanna, A.4    Chessa, M.F.5    Biggio, G.6
  • 7
    • 0033823084 scopus 로고    scopus 로고
    • Adenosine: does it have a neuroprotective role after all?
    • De Mendonca A., Sebastiao A.M., and Ribeiro J.A. Adenosine: does it have a neuroprotective role after all?. Brain Res. Rev. 33 (2000) 258-274
    • (2000) Brain Res. Rev. , vol.33 , pp. 258-274
    • De Mendonca, A.1    Sebastiao, A.M.2    Ribeiro, J.A.3
  • 8
    • 0022332956 scopus 로고
    • The physiological role of adenosine in the central nervous system
    • Dunwiddie T.V. The physiological role of adenosine in the central nervous system. Int. Rev. Neurobiol. 27 (1985) 63-139
    • (1985) Int. Rev. Neurobiol. , vol.27 , pp. 63-139
    • Dunwiddie, T.V.1
  • 10
    • 0030861647 scopus 로고    scopus 로고
    • Adenosine-dopamine receptor-receptor interactions as an integrative mechanism in the basal ganglia
    • Ferr S., Fredholm B.B., Morelli M., and Fuxe K. Adenosine-dopamine receptor-receptor interactions as an integrative mechanism in the basal ganglia. Trends Neurosci. 20 (1997) 482-487
    • (1997) Trends Neurosci. , vol.20 , pp. 482-487
    • Ferr, S.1    Fredholm, B.B.2    Morelli, M.3    Fuxe, K.4
  • 12
    • 0026620868 scopus 로고
    • Role of GABA in the genesis of chemconvulsant seizures
    • Gale K. Role of GABA in the genesis of chemconvulsant seizures. Toxicol. Lett. 64-65 (1992) 417-428
    • (1992) Toxicol. Lett. , vol.64-65 , pp. 417-428
    • Gale, K.1
  • 15
    • 0028999525 scopus 로고
    • 3H]-AMPA binding sites in rat hippocampus
    • 3H]-AMPA binding sites in rat hippocampus. Br. J. Pharmacol. 115 (1995) 295-301
    • (1995) Br. J. Pharmacol. , vol.115 , pp. 295-301
    • Henley, J.M.1
  • 16
    • 0035958067 scopus 로고    scopus 로고
    • 2A adenosine receptors antagonizes apoptosis due to serum deprivation in PC12 cells
    • 2A adenosine receptors antagonizes apoptosis due to serum deprivation in PC12 cells. J. Biol. Chem. 276 17 (2001) 13838-13846
    • (2001) J. Biol. Chem. , vol.276 , Issue.17 , pp. 13838-13846
    • Huang, N.K.1    Lin, Y.W.2    Huang, C.L.3    Messing, R.O.4    Chern, Y.5
  • 18
    • 33847005101 scopus 로고    scopus 로고
    • Inflammation induces mitochondrial dysfunction and dopaminergic neurodegeneration in the nigristriatal system
    • Hunter R.L., Dragicevic N., Seifert K., Choi D.Y., Liu M., Kim H.C., et al. Inflammation induces mitochondrial dysfunction and dopaminergic neurodegeneration in the nigristriatal system. J. Neurochem. 100 (2007) 1375-1386
    • (2007) J. Neurochem. , vol.100 , pp. 1375-1386
    • Hunter, R.L.1    Dragicevic, N.2    Seifert, K.3    Choi, D.Y.4    Liu, M.5    Kim, H.C.6
  • 20
    • 0034683193 scopus 로고    scopus 로고
    • Phenidone prevents kainate-induced neurotoxicity via antioxidant mechanisms
    • Kim H.C., Jhoo W.K., Bing G., Shin E.J., Wie M.B., Kim W.K., et al. Phenidone prevents kainate-induced neurotoxicity via antioxidant mechanisms. Brain Res. 874 (2000) 15-23
    • (2000) Brain Res. , vol.874 , pp. 15-23
    • Kim, H.C.1    Jhoo, W.K.2    Bing, G.3    Shin, E.J.4    Wie, M.B.5    Kim, W.K.6
  • 22
    • 11144356904 scopus 로고    scopus 로고
    • Selegiline potentiates the effects of EGb 761 in response to ischemic brain injury
    • Kwon Y.S., Ann H.S., Nabeshima T., Shin E.J., Kim W.K., Jhoo J.H., et al. Selegiline potentiates the effects of EGb 761 in response to ischemic brain injury. Neurochem. Int. 45 (2004) 157-170
    • (2004) Neurochem. Int. , vol.45 , pp. 157-170
    • Kwon, Y.S.1    Ann, H.S.2    Nabeshima, T.3    Shin, E.J.4    Kim, W.K.5    Jhoo, J.H.6
  • 23
    • 0025087596 scopus 로고
    • Sensitive and rapid quantitation of oxygen reactive species formation in rat synaptosomes
    • Lebel C.P., and Bondy S.C. Sensitive and rapid quantitation of oxygen reactive species formation in rat synaptosomes. Neurochem. Int. 17 (1990) 435-440
    • (1990) Neurochem. Int. , vol.17 , pp. 435-440
    • Lebel, C.P.1    Bondy, S.C.2
  • 24
    • 0035853065 scopus 로고    scopus 로고
    • Activation of Trk neurotrophin receptors in the absence of neurotrophins
    • Lee F.S., and Chao M.V. Activation of Trk neurotrophin receptors in the absence of neurotrophins. Proc. Natl. Acad. Sci. U.S.A. 98 6 (2001) 3555-3560
    • (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , Issue.6 , pp. 3555-3560
    • Lee, F.S.1    Chao, M.V.2
  • 25
    • 0037036187 scopus 로고    scopus 로고
    • Protective effect of ginsenosides, active ingredients of Panax ginseng, on kainic acid-induced neurotoxicity in rat hippocampus
    • Lee J.H., Kim S.R., Bae C.S., Kim D., Hong H., and Nah S. Protective effect of ginsenosides, active ingredients of Panax ginseng, on kainic acid-induced neurotoxicity in rat hippocampus. Neurosci. Lett. 325 (2002) 129-133
    • (2002) Neurosci. Lett. , vol.325 , pp. 129-133
    • Lee, J.H.1    Kim, S.R.2    Bae, C.S.3    Kim, D.4    Hong, H.5    Nah, S.6
  • 28
    • 0027418419 scopus 로고
    • The glutamatergic nerve terminal
    • Nicholls D.G. The glutamatergic nerve terminal. Eur. J. Biochem. 212 (1993) 613-631
    • (1993) Eur. J. Biochem. , vol.212 , pp. 613-631
    • Nicholls, D.G.1
  • 30
    • 0015309163 scopus 로고
    • Modification of seizure activity by electric stimulation: II. Motor seizure
    • Racine R.J. Modification of seizure activity by electric stimulation: II. Motor seizure. EEG Clin. Neurophysiol. 32 (1972) 281-294
    • (1972) EEG Clin. Neurophysiol. , vol.32 , pp. 281-294
    • Racine, R.J.1
  • 32
    • 0032710943 scopus 로고    scopus 로고
    • Effects of adenosine and gamma-aminobutyric acid A receptor antagonists on N-methyl-d-aspartate induced neurotoxicity in the rat hippocampus
    • Robledo P., Ursu G., and Mahy N. Effects of adenosine and gamma-aminobutyric acid A receptor antagonists on N-methyl-d-aspartate induced neurotoxicity in the rat hippocampus. Hippocampus 9 5 (1999) 527-533
    • (1999) Hippocampus , vol.9 , Issue.5 , pp. 527-533
    • Robledo, P.1    Ursu, G.2    Mahy, N.3
  • 33
    • 12944327375 scopus 로고    scopus 로고
    • 2A receptors: possible involvements of the striatal reduction in AP-1 DNA binding activity and proenkephalin gene expression
    • 2A receptors: possible involvements of the striatal reduction in AP-1 DNA binding activity and proenkephalin gene expression. Behav. Brain Res. 158 (2005) 143-157
    • (2005) Behav. Brain Res. , vol.158 , pp. 143-157
    • Shin, E.J.1    Nabeshima, T.2    Suh, H.W.3    Jhoo, W.K.4    Oh, K.W.5    Lim, Y.K.6
  • 34
    • 39149091703 scopus 로고    scopus 로고
    • Kainate-induced mitochondrial oxidative stress contributes to hippocampal degeneration in senescence-accelerated mice
    • Shin E.J., Jeong J.H., Bing G., Park E.S., Chae J.S., Yen T.P.H., et al. Kainate-induced mitochondrial oxidative stress contributes to hippocampal degeneration in senescence-accelerated mice. Cell Signal 20 (2008) 645-658
    • (2008) Cell Signal , vol.20 , pp. 645-658
    • Shin, E.J.1    Jeong, J.H.2    Bing, G.3    Park, E.S.4    Chae, J.S.5    Yen, T.P.H.6
  • 35
    • 40949113606 scopus 로고    scopus 로고
    • Role of glutathione peroxidase in the ontogeny of hippocampal oxidative stress and kainate seizure sensitivity in the genetically epilepsy-prone rats
    • Shin E.J., Ko K.H., Kim W.K., Chae J.S., Yen T.P., Kim H.J., et al. Role of glutathione peroxidase in the ontogeny of hippocampal oxidative stress and kainate seizure sensitivity in the genetically epilepsy-prone rats. Neurochem. Int. 52 (2008) 1134-1147
    • (2008) Neurochem. Int. , vol.52 , pp. 1134-1147
    • Shin, E.J.1    Ko, K.H.2    Kim, W.K.3    Chae, J.S.4    Yen, T.P.5    Kim, H.J.6
  • 36
    • 0028057773 scopus 로고    scopus 로고
    • Kainic acid seizures in the rat
    • Sperk G. Kainic acid seizures in the rat. Prog. Neurobiol. 42 (1997) 1-32
    • (1997) Prog. Neurobiol. , vol.42 , pp. 1-32
    • Sperk, G.1
  • 37
    • 0028092942 scopus 로고
    • Electrical stimulation of the kindled hippocampus briefly increases excellular dopamine in the nucleus accumbens
    • Strecker R.E., and Moneta M.E. Electrical stimulation of the kindled hippocampus briefly increases excellular dopamine in the nucleus accumbens. Neurosci. Lett. 176 (1994) 173-177
    • (1994) Neurosci. Lett. , vol.176 , pp. 173-177
    • Strecker, R.E.1    Moneta, M.E.2
  • 38
    • 37249068571 scopus 로고    scopus 로고
    • 2A receptors are required for normal BDNF levels and BDNF-induced potentiation of synaptic transmission in the mouse hippocampus
    • 2A receptors are required for normal BDNF levels and BDNF-induced potentiation of synaptic transmission in the mouse hippocampus. J. Neurochem. 104 1 (2008) 279-286
    • (2008) J. Neurochem. , vol.104 , Issue.1 , pp. 279-286
    • Tebano, M.T.1    Martier, A.2    Potenza, R.L.3    Grò, C.4    Pepponi, R.5    Armida, M.6
  • 39
    • 0002358665 scopus 로고
    • The separation of synaptic vesicles from nerve-ending particles ("synaptosomes")
    • Whittaker V.P., Michaelson I.A., and Kirkland R.J. The separation of synaptic vesicles from nerve-ending particles ("synaptosomes"). Biochem. J. 90 (1964) 293-303
    • (1964) Biochem. J. , vol.90 , pp. 293-303
    • Whittaker, V.P.1    Michaelson, I.A.2    Kirkland, R.J.3
  • 40
    • 0031638281 scopus 로고    scopus 로고
    • Gut and brain effects of American ginseng root on brainstem neuronal activities in rats
    • Yuan C.S., Wu J.A., Lowell T., and Gu M. Gut and brain effects of American ginseng root on brainstem neuronal activities in rats. Am. J. Chin. Med. 26 (1998) 47-55
    • (1998) Am. J. Chin. Med. , vol.26 , pp. 47-55
    • Yuan, C.S.1    Wu, J.A.2    Lowell, T.3    Gu, M.4


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