P27 protein protects metabolically stressed cardiomyocytes from apoptosis by promoting autophagy

Journal of Biological Chemistry

Volumn 289, Issue 24, 2014, Pages 16924-16935

  Sun, Xuetao ^a   Momen, Abdul ^a   Wu, Jun ^a   Noyan, Hossein ^a   Li, Renke ^a,b   Von Harsdorf, Rüdiger ^a,b,c,d   Husain, Mansoor ^a,b,c,d,e  

^a UNIVERSITY HEALTH NETWORK   (Canada)

^b UNIVERSITY HEALTH NETWORK   (Canada)

^c UNIVERSITY HEALTH NETWORK   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

^e UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BIOELECTRIC POTENTIALS; CELL DEATH; CELL PROLIFERATION; HEART; PROTEINS;

BASAL CONDITIONS; CARDIAC FUNCTIONS; CATABOLIC PROCESS; GENETIC APPROACH; GLUCOSE DEPRIVATION; METABOLIC STRESS; MYOCARDIAL INFARCTION; MYOCARDIAL ISCHEMIA;

GLUCOSE;

3 METHYLADENINE; AUTOPHAGY PROTEIN 5; BAFILOMYCIN A1; CASPASE 3; CHLOROQUINE; GLUCOSE; LENTIVIRUS VECTOR; MICROTUBULE ASSOCIATED PROTEIN; MICROTUBULE ASSOCIATED PROTEIN LIGHT CHAIN 3; PROTEIN P27; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL SURVIVAL; CONTROLLED STUDY; CORONARY ARTERY LIGATION; DOWN REGULATION; HEART INFARCTION; HEART INFARCTION SIZE; HEART MUSCLE CELL; IN VITRO STUDY; IN VIVO STUDY; METABOLIC STRESS; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT;

APOPTOSIS; AUTOPHAGY; CARDIAC METABOLISM; CARDIOVASCULAR DISEASE; HEART FAILURE; P27;

ANIMALS; APOPTOSIS; AUTOPHAGY; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P27; GLUCOSE; MICE; MICE, INBRED C57BL; MYOCARDIAL INFARCTION; MYOCYTES, CARDIAC; PROTEINS; RATS; RATS, WISTAR;

EID: 84902440212     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.542795     Document Type: Article

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