Membrane-tethered peptides patterned after the TRP domain (TRPducins) selectively inhibit TRPV1 channel activity

FASEB Journal

Volumn 25, Issue 5, 2011, Pages 1628-1640

  Valente, Pierluigi ^a,d   Fernández Carvajal, Asia ^a   Camprubí Robles, María ^a,e   Gomis, Ana ^b   Quirce, Susana ^b   Viana, Félix ^b   Fernández Ballester, Gregorio ^a   González Ros, José M ^a   Belmonte, Carlos ^b   Planells Cases, Rosa ^c   Ferrer Montiel, Antonio ^a  

^a MIGUEL HERNÁNDEZ UNIVERSITY   (Spain)

^b INSTITUTO DE NEUROCIENCIAS   (Spain)

^c CENTRO DE INVESTIGACIÓN PRÍNCIPE FELIPE   (Spain)

^d ISTITUTO ITALIANO DI TECNOLOGIA   (Italy)

^e INNSBRUCK MEDICAL UNIVERSITY   (Austria)

Author keywords

Analgesia; Inflammation; Ionotropic receptors; Pain; Pepducin

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; CAPSAICIN; DD 01050; LIPOPEPTIDE; MEMBRANE TETHERED PEPTIDE; TRANSIENT RECEPTOR POTENTIAL CHANNEL; UNCLASSIFIED DRUG; VANILLOID RECEPTOR; VANILLOID RECEPTOR 1; VANILLOID RECEPTOR 1 ANTAGONIST;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CELL MEMBRANE PERMEABILITY; CHANNEL GATING; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DRUG EFFICACY; HUMAN; HUMAN CELL; IC 50; IMMUNOCYTOCHEMISTRY; MALE; MEMBRANE CURRENT; MOUSE; NERVE FIBER; NEWBORN; NONHUMAN; PALMITOYLATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN PROTEIN INTERACTION; RAT; SENSORY NERVE CELL;

ANIMALS; ANIMALS, NEWBORN; CAPSAICIN; CELL LINE; CELLS, CULTURED; ELECTROPHYSIOLOGY; HEK293 CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; PEPTIDES; RATS; TRPV CATION CHANNELS;

RATTUS;

EID: 79955647249     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.10-174433     Document Type: Article

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