-
1
-
-
84874373992
-
SecYEG activates GTPases to drive the completion of cotranslational protein targeting
-
Akopian, D., K. Dalal, K. Shen, F. Duong, and S.O. Shan. 2013. SecYEG activates GTPases to drive the completion of cotranslational protein targeting. J. Cell Biol. 200:397-405. http://dx.doi.org/10.1083/jcb.201208045
-
(2013)
J. Cell Biol.
, vol.200
, pp. 397-405
-
-
Akopian, D.1
Dalal, K.2
Shen, K.3
Duong, F.4
Shan, S.O.5
-
2
-
-
79951826865
-
The crystal structure of the signal recognition particle in complex with its receptor
-
Ataide, S.F., N. Schmitz, K. Shen, A. Ke, S.O. Shan, J.A. Doudna, and N. Ban. 2011. The crystal structure of the signal recognition particle in complex with its receptor. Science. 331:881-886. http://dx.doi.org/10.1126/science.1196473
-
(2011)
Science.
, vol.331
, pp. 881-886
-
-
Ataide, S.F.1
Schmitz, N.2
Shen, K.3
Ke, A.4
Shan, S.O.5
Doudna, J.A.6
Ban, N.7
-
3
-
-
43249083239
-
Signal sequence-independent membrane targeting of ribosomes containing short nascent peptides within the exit tunnel
-
Bornemann, T., J. Jöckel, M.V. Rodnina, and W. Wintermeyer. 2008. Signal sequence-independent membrane targeting of ribosomes containing short nascent peptides within the exit tunnel. Nat. Struct. Mol. Biol. 15:494-499. http://dx.doi.org/10.1038/nsmb.1402
-
(2008)
Nat. Struct. Mol. Biol.
, vol.15
, pp. 494-499
-
-
Bornemann, T.1
Jöckel, J.2
Rodnina, M.V.3
Wintermeyer, W.4
-
4
-
-
67549141512
-
Two cooperating helices constitute the lipid-binding domain of the bacterial SRP receptor
-
Braig, D., C. Bär, J.-O. Thumfart, and H.-G. Koch. 2009. Two cooperating helices constitute the lipid-binding domain of the bacterial SRP receptor. J. Mol. Biol. 390:401-413. http://dx.doi.org/10.1016/j.jmb.2009.04.061
-
(2009)
J. Mol. Biol.
, vol.390
, pp. 401-413
-
-
Braig, D.1
Bär, C.2
Thumfart, J.-O.3
Koch, H.-G.4
-
5
-
-
79959912257
-
Signal sequence-independent SRP-SR complex formation at the membrane suggests an alternative targeting pathway within the SRP cycle
-
Braig, D., M. Mircheva, I. Sachelaru, E.O. van der Sluis, L. Sturm, R. Beckmann, and H.-G. Koch. 2011. Signal sequence-independent SRP-SR complex formation at the membrane suggests an alternative targeting pathway within the SRP cycle. Mol. Biol. Cell. 22:2309-2323. http://dx.doi.org/10.1091/mbc.E11-02-0152
-
(2011)
Mol. Biol. Cell.
, vol.22
, pp. 2309-2323
-
-
Braig, D.1
Mircheva, M.2
Sachelaru, I.3
van der Sluis, E.O.4
Sturm, L.5
Beckmann, R.6
Koch, H.-G.7
-
6
-
-
12144272096
-
Identification of cytoplasmic residues of Sec61p involved in ribosome binding and cotranslational translocation
-
Cheng, Z.L., Y. Jiang, E.C. Mandon, and R. Gilmore. 2005. Identification of cytoplasmic residues of Sec61p involved in ribosome binding and cotranslational translocation. J. Cell Biol. 168:67-77. http://dx.doi.org/10.1083/jcb.200408188
-
(2005)
J. Cell Biol.
, vol.168
, pp. 67-77
-
-
Cheng, Z.L.1
Jiang, Y.2
Mandon, E.C.3
Gilmore, R.4
-
7
-
-
62849101877
-
Delivering proteins for export from the cytosol
-
Cross, B.C.S., I. Sinning, J. Luirink, and S. High. 2009. Delivering proteins for export from the cytosol. Nat. Rev. Mol. Cell Biol. 10:255-264. http://dx.doi.org/10.1038/nrm2657
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, pp. 255-264
-
-
Cross, B.C.S.1
Sinning, I.2
Luirink, J.3
High, S.4
-
8
-
-
77954733211
-
Reconstitution of the SecY translocon in nanodiscs
-
Dalal, K., and F. Duong. 2010. Reconstitution of the SecY translocon in nanodiscs. Methods Mol. Biol. 619:145-156. http://dx.doi.org/10.1007/978-1-60327-412-8_9
-
(2010)
Methods Mol. Biol.
, vol.619
, pp. 145-156
-
-
Dalal, K.1
Duong, F.2
-
9
-
-
79960923840
-
Defining the specificity of cotranslationally acting chaperones by systematic analysis of mRNAs associated with ribosome-nascent chain complexes
-
del Alamo, M., D.J. Hogan, S. Pechmann, V. Albanese, P.O. Brown, and J. Frydman. 2011. Defining the specificity of cotranslationally acting chaperones by systematic analysis of mRNAs associated with ribosome-nascent chain complexes. PLoS Biol. 9:e1001100. http://dx.doi.org/10.1371/journal.pbio.1001100
-
(2011)
PLoS Biol.
, vol.9
-
-
del Alamo, M.1
Hogan, D.J.2
Pechmann, S.3
Albanese, V.4
Brown, P.O.5
Frydman, J.6
-
10
-
-
0027523180
-
Titration of protein transport activity by incremental changes in signal peptide hydrophobicity
-
Doud, S.K., M.M. Chou, and D.A. Kendall. 1993. Titration of protein transport activity by incremental changes in signal peptide hydrophobicity. Biochemistry. 32:1251-1256. http://dx.doi.org/10.1021/bi00056a008
-
(1993)
Biochemistry.
, vol.32
, pp. 1251-1256
-
-
Doud, S.K.1
Chou, M.M.2
Kendall, D.A.3
-
11
-
-
0030959069
-
Distinct catalytic roles of the SecYE, SecG and SecDFyajC subunits of preprotein translocase holoenzyme
-
Duong, F., and W. Wickner. 1997. Distinct catalytic roles of the SecYE, SecG and SecDFyajC subunits of preprotein translocase holoenzyme. EMBO J. 16:2756-2768. http://dx.doi.org/10.1093/emboj/16.10.2756
-
(1997)
EMBO J.
, vol.16
, pp. 2756-2768
-
-
Duong, F.1
Wickner, W.2
-
12
-
-
67650173024
-
The lateral gate of SecYEG opens during protein translocation
-
du Plessis, D.J.F., G. Berrelkamp, N. Nouwen, and A.J.M. Driessen. 2009. The lateral gate of SecYEG opens during protein translocation. J. Biol. Chem. 284:15805-15814. http://dx.doi.org/10.1074/jbc.M901855200
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 15805-15814
-
-
du Plessis, D.J.F.1
Berrelkamp, G.2
Nouwen, N.3
Driessen, A.J.M.4
-
13
-
-
0347584006
-
Substrate twinning activates the signal recognition particle and its receptor
-
Egea, P.F., S.O. Shan, J. Napetschnig, D.F. Savage, P. Walter, and R.M. Stroud. 2004. Substrate twinning activates the signal recognition particle and its receptor. Nature. 427:215-221. http://dx.doi.org/10.1038/nature02250
-
(2004)
Nature.
, vol.427
, pp. 215-221
-
-
Egea, P.F.1
Shan, S.O.2
Napetschnig, J.3
Savage, D.F.4
Walter, P.5
Stroud, R.M.6
-
14
-
-
0038719738
-
Signal recognition particle binds to ribosome-bound signal sequences with fluorescence-detected subnanomolar affinity that does not diminish as the nascent chain lengthens
-
Flanagan, J.J., J.C. Chen, Y.W. Miao, Y.L. Shao, J.L. Lin, P.E. Bock, and A.E. Johnson. 2003. Signal recognition particle binds to ribosome-bound signal sequences with fluorescence-detected subnanomolar affinity that does not diminish as the nascent chain lengthens. J. Biol. Chem. 278:18628-18637. http://dx.doi.org/10.1074/jbc.M300173200
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 18628-18637
-
-
Flanagan, J.J.1
Chen, J.C.2
Miao, Y.W.3
Shao, Y.L.4
Lin, J.L.5
Bock, P.E.6
Johnson, A.E.7
-
15
-
-
0346373753
-
Heterodimeric GTPase core of the SRP targeting complex
-
Focia, P.J., I.V. Shepotinovskaya, J.A. Seidler, and D.M. Freymann. 2004. Heterodimeric GTPase core of the SRP targeting complex. Science. 303:373-377. http://dx.doi.org/10.1126/science.1090827
-
(2004)
Science.
, vol.303
, pp. 373-377
-
-
Focia, P.J.1
Shepotinovskaya, I.V.2
Seidler, J.A.3
Freymann, D.M.4
-
16
-
-
67349250817
-
It takes two to tango: regulation of G proteins by dimerization
-
Gasper, R., S. Meyer, K. Gotthardt, M. Sirajuddin, and A. Wittinghofer. 2009. It takes two to tango: regulation of G proteins by dimerization. Nat. Rev. Mol. Cell Biol. 10:423-429. http://dx.doi.org/10.1038/nrm2689
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, pp. 423-429
-
-
Gasper, R.1
Meyer, S.2
Gotthardt, K.3
Sirajuddin, M.4
Wittinghofer, A.5
-
17
-
-
0037406142
-
The signal recognition particle binds to protein L23 at the peptide exit of the Escherichia coli ribosome
-
Gu, S.Q., F. Peske, H.J. Wieden, M.V. Rodnina, and W. Wintermeyer. 2003. The signal recognition particle binds to protein L23 at the peptide exit of the Escherichia coli ribosome. RNA. 9:566-573. http://dx.doi.org/10.1261/rna.2196403
-
(2003)
RNA.
, vol.9
, pp. 566-573
-
-
Gu, S.Q.1
Peske, F.2
Wieden, H.J.3
Rodnina, M.V.4
Wintermeyer, W.5
-
18
-
-
79952363483
-
Structural basis of signal-sequence recognition by the signal recognition particle
-
Hainzl, T., S.H. Huang, G. Meriläinen, K. Brännström, and A.E. Sauer-Eriksson. 2011. Structural basis of signal-sequence recognition by the signal recognition particle. Nat. Struct. Mol. Biol. 18:389-391. http://dx.doi.org/10.1038/nsmb.1994
-
(2011)
Nat. Struct. Mol. Biol.
, vol.18
, pp. 389-391
-
-
Hainzl, T.1
Huang, S.H.2
Meriläinen, G.3
Brännström, K.4
Sauer-Eriksson, A.E.5
-
19
-
-
33751325296
-
Following the signal sequence from ribosomal tunnel exit to signal recognition particle
-
Halic, M., M. Blau, T. Becker, T. Mielke, M.R. Pool, K. Wild, I. Sinning, and R. Beckmann. 2006a. Following the signal sequence from ribosomal tunnel exit to signal recognition particle. Nature. 444:507-511. http://dx.doi.org/10.1038/nature05326
-
(2006)
Nature.
, vol.444
, pp. 507-511
-
-
Halic, M.1
Blau, M.2
Becker, T.3
Mielke, T.4
Pool, M.R.5
Wild, K.6
Sinning, I.7
Beckmann, R.8
-
20
-
-
33646442605
-
Signal recognition particle receptor exposes the ribosomal translocon binding site
-
Halic, M., M. Gartmann, O. Schlenker, T. Mielke, M.R. Pool, I. Sinning, and R. Beckmann. 2006b. Signal recognition particle receptor exposes the ribosomal translocon binding site. Science. 312:745-747. http://dx.doi.org/10.1126/science.1124864
-
(2006)
Science.
, vol.312
, pp. 745-747
-
-
Halic, M.1
Gartmann, M.2
Schlenker, O.3
Mielke, T.4
Pool, M.R.5
Sinning, I.6
Beckmann, R.7
-
21
-
-
84870817496
-
Dynamic switch of the signal recognition particle from scanning to targeting
-
Holtkamp, W., S. Lee, T. Bornemann, T. Senyushkina, M.V. Rodnina, and W. Wintermeyer. 2012. Dynamic switch of the signal recognition particle from scanning to targeting. Nat. Struct. Mol. Biol. 19:1332-1337. http://dx.doi.org/10.1038/nsmb.2421
-
(2012)
Nat. Struct. Mol. Biol.
, vol.19
, pp. 1332-1337
-
-
Holtkamp, W.1
Lee, S.2
Bornemann, T.3
Senyushkina, T.4
Rodnina, M.V.5
Wintermeyer, W.6
-
22
-
-
77953025666
-
Recognition of a signal peptide by the signal recognition particle
-
Janda, C.Y., J. Li, C. Oubridge, H. Hernández, C.V. Robinson, and K. Nagai. 2010. Recognition of a signal peptide by the signal recognition particle. Nature. 465:507-510. http://dx.doi.org/10.1038/nature08870
-
(2010)
Nature.
, vol.465
, pp. 507-510
-
-
Janda, C.Y.1
Li, J.2
Oubridge, C.3
Hernández, H.4
Robinson, C.V.5
Nagai, K.6
-
23
-
-
0029096050
-
A posttargeting signal sequence recognition event in the endoplasmic reticulum membrane
-
Jungnickel, B., and T.A. Rapoport. 1995. A posttargeting signal sequence recognition event in the endoplasmic reticulum membrane. Cell. 82:261-270. http://dx.doi.org/10.1016/0092-8674(95)90313-5
-
(1995)
Cell.
, vol.82
, pp. 261-270
-
-
Jungnickel, B.1
Rapoport, T.A.2
-
24
-
-
80455155003
-
A single copy of SecYEG is sufficient for preprotein translocation
-
Kedrov, A., I. Kusters, V.V. Krasnikov, and A.J.M. Driessen. 2011. A single copy of SecYEG is sufficient for preprotein translocation. EMBO J. 30:4387-4397. http://dx.doi.org/10.1038/emboj.2011.314
-
(2011)
EMBO J.
, vol.30
, pp. 4387-4397
-
-
Kedrov, A.1
Kusters, I.2
Krasnikov, V.V.3
Driessen, A.J.M.4
-
25
-
-
0032563163
-
Crystal structure of the signal sequence binding subunit of the signal recognition particle
-
Keenan, R.J., D.M. Freymann, P. Walter, and R.M. Stroud. 1998. Crystal structure of the signal sequence binding subunit of the signal recognition particle. Cell. 94:181-191. http://dx.doi.org/10.1016/S0092-8674(00)81418-X
-
(1998)
Cell.
, vol.94
, pp. 181-191
-
-
Keenan, R.J.1
Freymann, D.M.2
Walter, P.3
Stroud, R.M.4
-
26
-
-
0034923677
-
The signal recognition particle
-
Keenan, R.J., D.M. Freymann, R.M. Stroud, and P. Walter. 2001. The signal recognition particle. Annu. Rev. Biochem. 70:755-775. http://dx.doi.org/10.1146/annurev.biochem.70.1.755
-
(2001)
Annu. Rev. Biochem.
, vol.70
, pp. 755-775
-
-
Keenan, R.J.1
Freymann, D.M.2
Stroud, R.M.3
Walter, P.4
-
27
-
-
66849109240
-
The ribosome as a platform for co-translational processing, folding and targeting of newly synthesized proteins
-
Kramer, G., D. Boehringer, N. Ban, and B. Bukau. 2009. The ribosome as a platform for co-translational processing, folding and targeting of newly synthesized proteins. Nat. Struct. Mol. Biol. 16:589-597. http://dx.doi.org/10.1038/nsmb.1614
-
(2009)
Nat. Struct. Mol. Biol.
, vol.16
, pp. 589-597
-
-
Kramer, G.1
Boehringer, D.2
Ban, N.3
Bukau, B.4
-
28
-
-
77955881180
-
Lipid activation of the signal recognition particle receptor provides spatial coordination of protein targeting
-
Lam, V.Q., D. Akopian, M. Rome, D. Henningsen, and S.O. Shan. 2010. Lipid activation of the signal recognition particle receptor provides spatial coordination of protein targeting. J. Cell Biol. 190:623-635. http://dx.doi.org/10.1083/jcb.201004129
-
(2010)
J. Cell Biol.
, vol.190
, pp. 623-635
-
-
Lam, V.Q.1
Akopian, D.2
Rome, M.3
Henningsen, D.4
Shan, S.O.5
-
29
-
-
37349107850
-
Ribosome binding of a single copy of the SecY complex: implications for protein translocation
-
Ménétret, J.-F., J. Schaletzky, W.M. Clemons Jr., A.R. Osborne, S.S. Skånland, C. Denison, S.P. Gygi, D.S. Kirkpatrick, E. Park, S.J. Ludtke, et al. 2007. Ribosome binding of a single copy of the SecY complex: implications for protein translocation. Mol. Cell. 28:1083-1092. http://dx.doi.org/10.1016/j.molcel.2007.10.034
-
(2007)
Mol. Cell.
, vol.28
, pp. 1083-1092
-
-
Ménétret, J.-F.1
Schaletzky, J.2
Clemons, W.M.3
Osborne, A.R.4
Skånland, S.S.5
Denison, C.6
Gygi, S.P.7
Kirkpatrick, D.S.8
Park, E.9
Ludtke, S.J.10
-
30
-
-
0024334898
-
Interaction of tRNA with 23S rRNA in the ribosomal A, P, and E sites
-
Moazed, D., and H.F. Noller. 1989. Interaction of tRNA with 23S rRNA in the ribosomal A, P, and E sites. Cell. 57:585-597. http://dx.doi.org/10.1016/0092-8674(89)90128-1
-
(1989)
Cell.
, vol.57
, pp. 585-597
-
-
Moazed, D.1
Noller, H.F.2
-
31
-
-
79955901001
-
Preserving the membrane barrier for small molecules during bacterial protein translocation
-
Park, E., and T.A. Rapoport. 2011. Preserving the membrane barrier for small molecules during bacterial protein translocation. Nature. 473:239-242. http://dx.doi.org/10.1038/nature10014
-
(2011)
Nature.
, vol.473
, pp. 239-242
-
-
Park, E.1
Rapoport, T.A.2
-
32
-
-
0035909810
-
Role of SRP RNA in the GTPase cycles of ffh and FtsY
-
Peluso, P., S.O. Shan, S. Nock, D. Herschlag, and P. Walter. 2001. Role of SRP RNA in the GTPase cycles of ffh and FtsY. Biochemistry. 40:15224-15233. http://dx.doi.org/10.1021/bi011639y
-
(2001)
Biochemistry.
, vol.40
, pp. 15224-15233
-
-
Peluso, P.1
Shan, S.O.2
Nock, S.3
Herschlag, D.4
Walter, P.5
-
33
-
-
4444221565
-
UCSF Chimera-a visualization system for exploratory research and analysis
-
Pettersen, E.F., T.D. Goddard, C.C. Huang, G.S. Couch, D.M. Greenblatt, E.C. Meng, and T.E. Ferrin. 2004. UCSF Chimera-a visualization system for exploratory research and analysis. J. Comput. Chem. 25:1605-1612. http://dx.doi.org/10.1002/jcc.20084
-
(2004)
J. Comput. Chem.
, vol.25
, pp. 1605-1612
-
-
Pettersen, E.F.1
Goddard, T.D.2
Huang, C.C.3
Couch, G.S.4
Greenblatt, D.M.5
Meng, E.C.6
Ferrin, T.E.7
-
34
-
-
0037162838
-
Distinct modes of signal recognition particle interaction with the ribosome
-
Pool, M.R., J. Stumm, T.A. Fulga, I. Sinning, and B. Dobberstein. 2002. Distinct modes of signal recognition particle interaction with the ribosome. Science. 297:1345-1348. http://dx.doi.org/10.1126/science.1072366
-
(2002)
Science.
, vol.297
, pp. 1345-1348
-
-
Pool, M.R.1
Stumm, J.2
Fulga, T.A.3
Sinning, I.4
Dobberstein, B.5
-
35
-
-
0025605808
-
An E. coli ribonucleoprotein containing 4.5S RNA resembles mammalian signal recognition particle
-
Poritz, M.A., H.D. Bernstein, K. Strub, D. Zopf, H. Wilhelm, and P. Walter. 1990. An E. coli ribonucleoprotein containing 4.5S RNA resembles mammalian signal recognition particle. Science. 250:1111-1117. http://dx.doi.org/10.1126/science.1701272
-
(1990)
Science.
, vol.250
, pp. 1111-1117
-
-
Poritz, M.A.1
Bernstein, H.D.2
Strub, K.3
Zopf, D.4
Wilhelm, H.5
Walter, P.6
-
36
-
-
36749001066
-
Protein translocation across the eukaryotic endoplasmic reticulum and bacterial plasma membranes
-
Rapoport, T.A. 2007. Protein translocation across the eukaryotic endoplasmic reticulum and bacterial plasma membranes. Nature. 450:663-669. http://dx.doi.org/10.1038/nature06384
-
(2007)
Nature.
, vol.450
, pp. 663-669
-
-
Rapoport, T.A.1
-
37
-
-
79953752538
-
Molecular mechanism of co-translational protein targeting by the signal recognition particle
-
Saraogi, I., and S.O. Shan. 2011. Molecular mechanism of co-translational protein targeting by the signal recognition particle. Traffic. 12:535-542. http://dx.doi.org/10.1111/j.1600-0854.2011.01171.x
-
(2011)
Traffic.
, vol.12
, pp. 535-542
-
-
Saraogi, I.1
Shan, S.O.2
-
38
-
-
80053079082
-
Site-specific fluorescent labeling of nascent proteins on the translating ribosome
-
Saraogi, I., D. Zhang, S. Chandrasekaran, and S.O. Shan. 2011. Site-specific fluorescent labeling of nascent proteins on the translating ribosome. J. Am. Chem. Soc. 133:14936-14939. http://dx.doi.org/10.1021/ja206626g
-
(2011)
J. Am. Chem. Soc.
, vol.133
, pp. 14936-14939
-
-
Saraogi, I.1
Zhang, D.2
Chandrasekaran, S.3
Shan, S.O.4
-
39
-
-
33751325833
-
Structure of the E. coli signal recognition particle bound to a translating ribosome
-
Schaffitzel, C., M. Oswald, I. Berger, T. Ishikawa, J.P. Abrahams, H.K. Koerten, R.I. Koning, and N. Ban. 2006. Structure of the E. coli signal recognition particle bound to a translating ribosome. Nature. 444:503-506. http://dx.doi.org/10.1038/nature05182
-
(2006)
Nature.
, vol.444
, pp. 503-506
-
-
Schaffitzel, C.1
Oswald, M.2
Berger, I.3
Ishikawa, T.4
Abrahams, J.P.5
Koerten, H.K.6
Koning, R.I.7
Ban, N.8
-
40
-
-
8844253060
-
Mechanism of Association and Reciprocal Activation of Two GTPases
-
Shan, S.O., R.M. Stroud, and P. Walter. 2004. Mechanism of Association and Reciprocal Activation of Two GTPases. PLoS Biol. 2:e320. http://dx.doi.org/10.1371/journal.pbio.0020320
-
(2004)
PLoS Biol.
, vol.2
-
-
Shan, S.O.1
Stroud, R.M.2
Walter, P.3
-
41
-
-
67651230544
-
Signal recognition particle (SRP) and SRP receptor: a new paradigm for multistate regulatory GTPases
-
Shan, S.O., S.L. Schmid, and X. Zhang. 2009. Signal recognition particle (SRP) and SRP receptor: a new paradigm for multistate regulatory GTPases. Biochemistry. 48:6696-6704. http://dx.doi.org/10.1021/bi9006989
-
(2009)
Biochemistry.
, vol.48
, pp. 6696-6704
-
-
Shan, S.O.1
Schmid, S.L.2
Zhang, X.3
-
42
-
-
77952331762
-
Transient tether between the SRP RNA and SRP receptor ensures efficient cargo delivery during cotranslational protein targeting
-
Shen, K., and S.O. Shan. 2010. Transient tether between the SRP RNA and SRP receptor ensures efficient cargo delivery during cotranslational protein targeting. Proc. Natl. Acad. Sci. USA. 107:7698-7703. http://dx.doi.org/10.1073/pnas.1002968107
-
(2010)
Proc. Natl. Acad. Sci. USA.
, vol.107
, pp. 7698-7703
-
-
Shen, K.1
Shan, S.O.2
-
43
-
-
79955005771
-
Synergistic actions between the SRP RNA and translating ribosome allow efficient delivery of the correct cargos during cotranslational protein targeting
-
Shen, K., X. Zhang, and S.O. Shan. 2011. Synergistic actions between the SRP RNA and translating ribosome allow efficient delivery of the correct cargos during cotranslational protein targeting. RNA. 17:892-902. http://dx.doi.org/10.1261/rna.2610411
-
(2011)
RNA.
, vol.17
, pp. 892-902
-
-
Shen, K.1
Zhang, X.2
Shan, S.O.3
-
44
-
-
84870979537
-
Activated GTPase movement on an RNA scaffold drives co-translational protein targeting
-
Shen, K., S. Arslan, D. Akopian, T. Ha, and S.O. Shan. 2012. Activated GTPase movement on an RNA scaffold drives co-translational protein targeting. Nature. 492:271-275. http://dx.doi.org/10.1038/nature11726
-
(2012)
Nature.
, vol.492
, pp. 271-275
-
-
Shen, K.1
Arslan, S.2
Akopian, D.3
Ha, T.4
Shan, S.O.5
-
45
-
-
0034602866
-
Role of Sec61α in the regulated transfer of the ribosome-nascent chain complex from the signal recognition particle to the translocation channel
-
Song, W.Q., D. Raden, E.C. Mandon, and R. Gilmore. 2000. Role of Sec61α in the regulated transfer of the ribosome-nascent chain complex from the signal recognition particle to the translocation channel. Cell. 100:333-343. http://dx.doi.org/10.1016/S0092-8674(00)80669-8
-
(2000)
Cell.
, vol.100
, pp. 333-343
-
-
Song, W.Q.1
Raden, D.2
Mandon, E.C.3
Gilmore, R.4
-
46
-
-
79959557410
-
Lipids trigger a conformational switch that regulates signal recognition particle (SRP)-mediated protein targeting
-
Stjepanovic, G., K. Kapp, G. Bange, C. Graf, R. Parlitz, K. Wild, M.P. Mayer, and I. Sinning. 2011. Lipids trigger a conformational switch that regulates signal recognition particle (SRP)-mediated protein targeting. J. Biol. Chem. 286:23489-23497. http://dx.doi.org/10.1074/jbc.M110.212340
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 23489-23497
-
-
Stjepanovic, G.1
Kapp, K.2
Bange, G.3
Graf, C.4
Parlitz, R.5
Wild, K.6
Mayer, M.P.7
Sinning, I.8
-
47
-
-
0038360877
-
Interplay of signal recognition particle and trigger factor at L23 near the nascent chain exit site on the Escherichia coli ribosome
-
Ullers, R.S., E.N.G. Houben, A. Raine, C.M. ten Hagen-Jongman, M. Ehrenberg, J. Brunner, B. Oudega, N. Harms, and J. Luirink. 2003. Interplay of signal recognition particle and trigger factor at L23 near the nascent chain exit site on the Escherichia coli ribosome. J. Cell Biol. 161:679-684. http://dx.doi.org/10.1083/jcb.200302130
-
(2003)
J. Cell Biol.
, vol.161
, pp. 679-684
-
-
Ullers, R.S.1
Houben, E.N.G.2
Raine, A.3
ten Hagen-Jongman, C.M.4
Ehrenberg, M.5
Brunner, J.6
Oudega, B.7
Harms, N.8
Luirink, J.9
-
48
-
-
0347192985
-
X-ray structure of a protein-conducting channel
-
van den Berg, B., W.M. Clemons Jr., I. Collinson, Y. Modis, E. Hartmann, S.C. Harrison, and T.A. Rapoport. 2004. X-ray structure of a protein-conducting channel. Nature. 427:36-44. http://dx.doi.org/10.1038/nature02218
-
(2004)
Nature.
, vol.427
, pp. 36-44
-
-
van den Berg, B.1
Clemons, W.M.2
Collinson, I.3
Modis, Y.4
Hartmann, E.5
Harrison, S.C.6
Rapoport, T.A.7
-
49
-
-
84858031326
-
Competitive binding of the SecA ATPase and ribosomes to the SecYEG translocon
-
Wu, Z.C., J. de Keyzer, A. Kedrov, and A.J.M. Driessen. 2012. Competitive binding of the SecA ATPase and ribosomes to the SecYEG translocon. J. Biol. Chem. 287:7885-7895. http://dx.doi.org/10.1074/jbc.M111.297911
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 7885-7895
-
-
Wu, Z.C.1
de Keyzer, J.2
Kedrov, A.3
Driessen, A.J.M.4
-
50
-
-
47849117948
-
Demonstration of a multistep mechanism for assembly of the SRP x SRP receptor complex: implications for the catalytic role of SRP RNA
-
Zhang, X., S. Kung, and S.O. Shan. 2008. Demonstration of a multistep mechanism for assembly of the SRP x SRP receptor complex: implications for the catalytic role of SRP RNA. J. Mol. Biol. 381:581-593. http://dx.doi.org/10.1016/j.jmb.2008.05.049
-
(2008)
J. Mol. Biol.
, vol.381
, pp. 581-593
-
-
Zhang, X.1
Kung, S.2
Shan, S.O.3
-
51
-
-
60549083291
-
Multiple conformational switches in a GTPase complex control co-translational protein targeting
-
Zhang, X., C. Schaffitzel, N. Ban, and S.O. Shan. 2009. Multiple conformational switches in a GTPase complex control co-translational protein targeting. Proc. Natl. Acad. Sci. USA. 106:1754-1759. http://dx.doi.org/10.1073/pnas.0808573106
-
(2009)
Proc. Natl. Acad. Sci. USA.
, vol.106
, pp. 1754-1759
-
-
Zhang, X.1
Schaffitzel, C.2
Ban, N.3
Shan, S.O.4
-
52
-
-
77952127782
-
Sequential checkpoints govern substrate selection during cotranslational protein targeting
-
Zhang, X., R. Rashid, K. Wang, and S.O. Shan. 2010. Sequential checkpoints govern substrate selection during cotranslational protein targeting. Science. 328:757-760. http://dx.doi.org/10.1126/science.1186743
-
(2010)
Science.
, vol.328
, pp. 757-760
-
-
Zhang, X.1
Rashid, R.2
Wang, K.3
Shan, S.O.4
-
53
-
-
79955585362
-
Direct visualization reveals dynamics of a transient intermediate during protein assembly
-
Zhang, X., V.Q. Lam, Y. Mou, T. Kimura, J. Chung, S. Chandrasekar, J.R. Winkler, S.L. Mayo, and S.O. Shan. 2011. Direct visualization reveals dynamics of a transient intermediate during protein assembly. Proc. Natl. Acad. Sci. USA. 108:6450-6455. http://dx.doi.org/10.1073/pnas.1019051108
-
(2011)
Proc. Natl. Acad. Sci. USA.
, vol.108
, pp. 6450-6455
-
-
Zhang, X.1
Lam, V.Q.2
Mou, Y.3
Kimura, T.4
Chung, J.5
Chandrasekar, S.6
Winkler, J.R.7
Mayo, S.L.8
Shan, S.O.9
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